LANZAFAME, MANUELA
LANZAFAME, MANUELA
Istituto di Genetica Molecolare "Luigi Luca Cavalli Sforza"
TFIIH stabilization recovers the DNA repair and transcription dysfunctions in thermo-sensitive trichothiodystrophy
2022 Lanzafame, M; Nardo, T; Ricotti, R; Pantaleoni, C; D'Arrigo, S; Stanzial, F; Benedicenti, F; Thomas, Ma; Stefanini, M; Orioli, D; Botta, E
Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation
2021 Lanzafame, M; Branca, G; Landi, C; Qiang, M; Vaz, B; Nardo, T; Ferri, D; Mura, M; Iben, S; Stefanini, M; Peverali, Af; Bini, L; Orioli, D.
Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma
2021 Witzigmann, Dominik; Grossen, Philip; Quintavalle, Cristina; Lanzafame, Manuela; Schenk, Susanne H; Tran, Xue-Ting; Englinger, Bernhard; Hauswirth, Patrick; Grünig, David; van Schoonhoven, Sushilla; Krähenbühl, Stephan; Terracciano, Luigi M; Berger, Walter; Piscuoglio, Salvatore; Quagliata, Luca; Rommelaere, Jean; Nüesch, Jürg P F; Huwyler, Jörg
Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens
2021 Montazeri, H.; Coto-Llerena, M.; Bianco, G.; Zangene, E.; Taha-Mehlitz, S.; Paradiso, V.; Srivatsa, S.; De Weck, A.; Roma, G.; Lanzafame, M.; Bolli, M.; Beerenwinkel, N.; Von Flue, M.; Terracciano, L. M.; Piscuoglio, S.; Ng, C. K. Y.
The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway
2021 Tlili, Hajer; Macovei, Anca; Buonocore, Daniela; Lanzafame, Manuela; Najjaa, Hanen; Lombardi, Anita; Pagano, Andrea; Dossena, Maurizia; Verri, Manuela; Arfa, Abdelkarim Ben; Neffati, Mohamed; Doria, Enrico
Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation
2020 Ghosh, Souvik; Guimaraes, Joao C; Lanzafame, Manuela; Schmidt, Alexander; Syed, Afzal Pasha; Dimitriades, Beatrice; Börsch, Anastasiya; Ghosh, Shreemoyee; Mittal, Nitish; Montavon, Thomas; Correia, Ana Luisa; Danner, Johannes; Meister, Gunter; Terracciano, Luigi M; Pfeffer, Sébastien; Piscuoglio, Salvatore; Zavolan, Mihaela
Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome.
2018 Calmels, N; Botta, E; Jia, N; Fawcett, H; Nardo, T; Nakazawa, Y; Lanzafame, M; Moriwaki, S; Sugita, K; Kubota, M; Obringer, C; Spitz, Ma; Stefanini, M; Laugel, V; Orioli, D; Ogi, T; Lehmann, Ar
Genetic profiling using plasma-derived cell-free DNA in therapy-naive hepatocellular carcinoma patients: A pilot study
2018 Ng C.K.Y.; Di Costanzo G.G.; Tosti N.; Paradiso V.; CotoLlerena M.; Roscigno G.; Perrina V.; Quintavalle C.; Boldanova T.; Wieland S.; MarinoMarsilia G.; Lanzafame M.; Quagliata L.; Condorelli G.; Matter M.S.; Tortora R.; Heim M.H.; Terracciano L.M.; Piscuoglio S.
High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models
2018 Quagliata, Luca; Quintavalle, Cristina; Lanzafame, Manuela; Matter, Matthias S.; Novello, Chiara; di Tommaso, Luca; Pressiani, Tiziana; Rimassa, Lorenza; Tornillo, Luigi; Roncalli, Massimo; Cillo, Clemente; Pallante, Pierlorenzo; Piscuoglio, Salvatore; Ng, Charlotte K. Y.; Terracciano, Luigi M.
GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
2016 Kuschal C.; Botta E.; Orioli D.; Digiovanna J.J.; Seneca S.; Keymolen K.; Tamura D.; Heller E.; Khan S.G.; Caligiuri G.; Lanzafame M.; Nardo T.; Ricotti R.; Peverali F.A.; Stephens R.; Zhao Y.; Lehmann A.R.; Baranello L.; Levens D.; Kraemer K.; Stefanini M.
Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells.
2016 Pascucci B.; D'Errico M.; Romagnoli A.; De Nuccio C.; Savino M.; Pietraforte D.; Lanzafame M.; Calcagnile A.S.; Fortini P.; Baccarini S.; Orioli D.; Degan P.; Visentin S.; Stefanini M.; Isidoro C.; Fimia G.M.; Dogliotti E.
Reference genes for gene expression analysis in proliferating and differentiating human keratinocytes
2015 Lanzafame, M; Botta, E; Teson, M; Fortugno, P; Zambruno, G; Stefanini, M; Orioli, D
TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin
2015 Arseni, L; Lanzafame, M; Compe, E; Fortugno, P; Afonsobarroso, A; Peverali, Fa; Lehmann, Ar; Zambruno, G; Egly, Jm; Stefanini, M; Orioli, D
The role of mitochondrial dysfunction in Cockayne Syndrome
2015 Mariarosaria D'Errico; Barbara Pascucci; Alessandra Romagnoli; Chiara De Nuccio; Miriam Savino; Donatella Pietraforte; Manuela Lanzafame; Angelo Salvatore Calcagnile; Paola Fortini; Sara Baccarini; Donata Orioli; Paolo Degan; Sergio Visentin; Miria Stefanini; Ciro Isidoro; Gian Maria Fimia; Eugenia Dogliotti
TFIIH-dependent transcriptional impairments contribute to the phenotypic differences associated with distinct XPD mutations
2014 Arseni L; Lanzafame M; Compe E; Fortugno P; AfonsoBarroso A; Peverali FA; Zambruno G; Egly JM; Stefanini M; Orioli D
TFIIH-dependent transcriptional impairments contribute to the phenotypic differences associated with distinct XPD mutations
2014 Orioli, D; Arseni, L; Lanzafame, M; Nardo, T; Botta, E; Peverali, Fa; Compe, E; Egly, Jm; Stefanini, M
Dalla conferma della diagnosi clinica dei pazienti alla dissezione dei pathways coinvolti nella risposta a stress ossidativo e radiazione UV
2013 Lanzafame M; Botta E; Nardo T; Garbelli M; Ricotti R; Orioli D; Stefanini M
Does CSA play a role in mitochondrial quality control?
2013 Pascucci, B; Lanzafame, M; Orioli, D; Stefanini, M; Fimia, G; Romagnoli, A; Visentin, S; De Nuccio, C; Calcagnile, A; Vaz, B; Degan, P; Dogliotti, E; D'Errico, M
Does CSA play a role in mitochondrial quality control?
2013 Pascucci B.; Lanzafame M.; Orioli D.; Stefanini M.; Fimia G.; Romagnoli A.; Visentin S.; De Nuccio C.; Calcagnile A.; Vaz B.; Degan P.; Dogliotti E.; D'Errico M.
From laboratory tests to functional characterisation of Cockayne syndrome
2013 Lanzafame, M; Vaz, B; Nardo, T; Botta, E; Orioli, D; Stefanini, M
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| TFIIH stabilization recovers the DNA repair and transcription dysfunctions in thermo-sensitive trichothiodystrophy | 1-gen-2022 | Lanzafame, M; Nardo, T; Ricotti, R; Pantaleoni, C; D'Arrigo, S; Stanzial, F; Benedicenti, F; Thomas, Ma; Stefanini, M; Orioli, D; Botta, E | |
| Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation | 1-gen-2021 | Lanzafame, M; Branca, G; Landi, C; Qiang, M; Vaz, B; Nardo, T; Ferri, D; Mura, M; Iben, S; Stefanini, M; Peverali, Af; Bini, L; Orioli, D. | |
| Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma | 1-gen-2021 | Witzigmann, Dominik; Grossen, Philip; Quintavalle, Cristina; Lanzafame, Manuela; Schenk, Susanne H; Tran, Xue-Ting; Englinger, Bernhard; Hauswirth, Patrick; Grünig, David; van Schoonhoven, Sushilla; Krähenbühl, Stephan; Terracciano, Luigi M; Berger, Walter; Piscuoglio, Salvatore; Quagliata, Luca; Rommelaere, Jean; Nüesch, Jürg P F; Huwyler, Jörg | |
| Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens | 1-gen-2021 | Montazeri, H.; Coto-Llerena, M.; Bianco, G.; Zangene, E.; Taha-Mehlitz, S.; Paradiso, V.; Srivatsa, S.; De Weck, A.; Roma, G.; Lanzafame, M.; Bolli, M.; Beerenwinkel, N.; Von Flue, M.; Terracciano, L. M.; Piscuoglio, S.; Ng, C. K. Y. | |
| The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway | 1-gen-2021 | Tlili, Hajer; Macovei, Anca; Buonocore, Daniela; Lanzafame, Manuela; Najjaa, Hanen; Lombardi, Anita; Pagano, Andrea; Dossena, Maurizia; Verri, Manuela; Arfa, Abdelkarim Ben; Neffati, Mohamed; Doria, Enrico | |
| Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation | 1-gen-2020 | Ghosh, Souvik; Guimaraes, Joao C; Lanzafame, Manuela; Schmidt, Alexander; Syed, Afzal Pasha; Dimitriades, Beatrice; Börsch, Anastasiya; Ghosh, Shreemoyee; Mittal, Nitish; Montavon, Thomas; Correia, Ana Luisa; Danner, Johannes; Meister, Gunter; Terracciano, Luigi M; Pfeffer, Sébastien; Piscuoglio, Salvatore; Zavolan, Mihaela | |
| Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome. | 1-gen-2018 | Calmels, N; Botta, E; Jia, N; Fawcett, H; Nardo, T; Nakazawa, Y; Lanzafame, M; Moriwaki, S; Sugita, K; Kubota, M; Obringer, C; Spitz, Ma; Stefanini, M; Laugel, V; Orioli, D; Ogi, T; Lehmann, Ar | |
| Genetic profiling using plasma-derived cell-free DNA in therapy-naive hepatocellular carcinoma patients: A pilot study | 1-gen-2018 | Ng C.K.Y.; Di Costanzo G.G.; Tosti N.; Paradiso V.; CotoLlerena M.; Roscigno G.; Perrina V.; Quintavalle C.; Boldanova T.; Wieland S.; MarinoMarsilia G.; Lanzafame M.; Quagliata L.; Condorelli G.; Matter M.S.; Tortora R.; Heim M.H.; Terracciano L.M.; Piscuoglio S. | |
| High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models | 1-gen-2018 | Quagliata, Luca; Quintavalle, Cristina; Lanzafame, Manuela; Matter, Matthias S.; Novello, Chiara; di Tommaso, Luca; Pressiani, Tiziana; Rimassa, Lorenza; Tornillo, Luigi; Roncalli, Massimo; Cillo, Clemente; Pallante, Pierlorenzo; Piscuoglio, Salvatore; Ng, Charlotte K. Y.; Terracciano, Luigi M. | |
| GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy | 1-gen-2016 | Kuschal C.; Botta E.; Orioli D.; Digiovanna J.J.; Seneca S.; Keymolen K.; Tamura D.; Heller E.; Khan S.G.; Caligiuri G.; Lanzafame M.; Nardo T.; Ricotti R.; Peverali F.A.; Stephens R.; Zhao Y.; Lehmann A.R.; Baranello L.; Levens D.; Kraemer K.; Stefanini M. | |
| Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells. | 1-gen-2016 | Pascucci B.; D'Errico M.; Romagnoli A.; De Nuccio C.; Savino M.; Pietraforte D.; Lanzafame M.; Calcagnile A.S.; Fortini P.; Baccarini S.; Orioli D.; Degan P.; Visentin S.; Stefanini M.; Isidoro C.; Fimia G.M.; Dogliotti E. | |
| Reference genes for gene expression analysis in proliferating and differentiating human keratinocytes | 1-gen-2015 | Lanzafame, M; Botta, E; Teson, M; Fortugno, P; Zambruno, G; Stefanini, M; Orioli, D | |
| TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin | 1-gen-2015 | Arseni, L; Lanzafame, M; Compe, E; Fortugno, P; Afonsobarroso, A; Peverali, Fa; Lehmann, Ar; Zambruno, G; Egly, Jm; Stefanini, M; Orioli, D | |
| The role of mitochondrial dysfunction in Cockayne Syndrome | 1-gen-2015 | Mariarosaria D'Errico; Barbara Pascucci; Alessandra Romagnoli; Chiara De Nuccio; Miriam Savino; Donatella Pietraforte; Manuela Lanzafame; Angelo Salvatore Calcagnile; Paola Fortini; Sara Baccarini; Donata Orioli; Paolo Degan; Sergio Visentin; Miria Stefanini; Ciro Isidoro; Gian Maria Fimia; Eugenia Dogliotti | |
| TFIIH-dependent transcriptional impairments contribute to the phenotypic differences associated with distinct XPD mutations | 1-gen-2014 | Arseni L; Lanzafame M; Compe E; Fortugno P; AfonsoBarroso A; Peverali FA; Zambruno G; Egly JM; Stefanini M; Orioli D | |
| TFIIH-dependent transcriptional impairments contribute to the phenotypic differences associated with distinct XPD mutations | 1-gen-2014 | Orioli, D; Arseni, L; Lanzafame, M; Nardo, T; Botta, E; Peverali, Fa; Compe, E; Egly, Jm; Stefanini, M | |
| Dalla conferma della diagnosi clinica dei pazienti alla dissezione dei pathways coinvolti nella risposta a stress ossidativo e radiazione UV | 1-gen-2013 | Lanzafame M; Botta E; Nardo T; Garbelli M; Ricotti R; Orioli D; Stefanini M | |
| Does CSA play a role in mitochondrial quality control? | 1-gen-2013 | Pascucci, B; Lanzafame, M; Orioli, D; Stefanini, M; Fimia, G; Romagnoli, A; Visentin, S; De Nuccio, C; Calcagnile, A; Vaz, B; Degan, P; Dogliotti, E; D'Errico, M | |
| Does CSA play a role in mitochondrial quality control? | 1-gen-2013 | Pascucci B.; Lanzafame M.; Orioli D.; Stefanini M.; Fimia G.; Romagnoli A.; Visentin S.; De Nuccio C.; Calcagnile A.; Vaz B.; Degan P.; Dogliotti E.; D'Errico M. | |
| From laboratory tests to functional characterisation of Cockayne syndrome | 1-gen-2013 | Lanzafame, M; Vaz, B; Nardo, T; Botta, E; Orioli, D; Stefanini, M |