GUIDI, ALESSANDRA
GUIDI, ALESSANDRA
Istituto di Biologia e Patologia Molecolari - IBPM
Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites
2022 Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
2022 Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G
(+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages
2020 Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma
Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy
2020 Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone
2020 Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M.
Luminescence-based, low- and medium-throughput assays for drug screening in schistosoma mansoni larval stage
2020 Guidi, Alessandra; Gimmelli, Roberto; Bresciani, Alberto; Ruberti, Giovina
Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents
2019 Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G
Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability.
2019 Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G.
Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production
2018 Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G
Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.
2017 Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G
Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.
2016 Guidi, Alessandra; Lalli, Cristiana; Perlas, Emerald; Bolasco, Giulia; Nibbio, Martina; Monteagudo, Edith; Bresciani, Alberto; Ruberti, Giovina
Application of RNAi to Genomic Drug Target Validation in Schistosomes
2015 Guidi, Alessandra; Mansour, Nuha R.; Paveley, Ross A.; Carruthers, Ian M.; Besnard, Jeremy; Hopkins, Andrew L.; Gilbert, Ian H.; Bickle, Quentin D.
Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni.
2015 Lalli C; Guidi A; Gennari N; Altamura S; Bresciani A; Ruberti G.
Structural and functional characterization of the enantiomers of the antischistosomal drug oxamniquine
2015 Alexander B. Taylor; Livia PicaMattoccia; Chiara M. Polcaro; Enrica Donati;Xiaohang Cao; Annalisa Basso; Alessandra Guidi; Anastasia R. Rugel; StephenP. Holloway; Timothy J. C. Anderson; P. John Hart;; Donato Cioli; PhilipT. LoVerde;
Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.
2015 Taylor, A B; Picamattoccia, L; Polcaro, C M; Donati, E; Cao, X; Basso, A; Guidi, A; Rugel, A R; Holloway, S P; Anderson, T J C; Hart, P J; Cioli, D; Loverde, P T
Schistosomiasis control: Praziquantel forever?
2014 Cioli D.; PicaMattoccia L.; Basso A.; Guidi A.
Use of Perhexiline
2014 Ruberti, G; Lalli, C; Guidi, A; Bresciani, A; Gennari, N; Paonessa, G; Nizzi, E
Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases
2012 Paveley, Ross A.; Mansour, Nuha R.; Hallyburton, Irene; Bleicher, Leo S.; Benn, Alex E.; Mikic, Ivana; Guidi, Alessandra; Gilbert, Ian H.; Hopkins, Andrew L.; Bickle, Quentin D.
Praziquantel efficacy and long-term appraisal of schistosomiasis control in Pemba Island.
2010 Guidi A; Andolina C; Makame Ame S; Albonico M; Cioli D; Juma Haji H.
Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni
2009 PicaMattoccia L; Doenhoff MJ; Valle C; Basso A; Troiani AR; Liberti P; Festucci A; Guidi A; Cioli D
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites | 1-gen-2022 | Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina | |
| Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors | 1-gen-2022 | Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G | |
| (+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages | 1-gen-2020 | Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma | |
| Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy | 1-gen-2020 | Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G | |
| Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone | 1-gen-2020 | Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M. | |
| Luminescence-based, low- and medium-throughput assays for drug screening in schistosoma mansoni larval stage | 1-gen-2020 | Guidi, Alessandra; Gimmelli, Roberto; Bresciani, Alberto; Ruberti, Giovina | |
| Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents | 1-gen-2019 | Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G | |
| Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability. | 1-gen-2019 | Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G. | |
| Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production | 1-gen-2018 | Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G | |
| Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production. | 1-gen-2017 | Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G | |
| Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems. | 1-gen-2016 | Guidi, Alessandra; Lalli, Cristiana; Perlas, Emerald; Bolasco, Giulia; Nibbio, Martina; Monteagudo, Edith; Bresciani, Alberto; Ruberti, Giovina | |
| Application of RNAi to Genomic Drug Target Validation in Schistosomes | 1-gen-2015 | Guidi, Alessandra; Mansour, Nuha R.; Paveley, Ross A.; Carruthers, Ian M.; Besnard, Jeremy; Hopkins, Andrew L.; Gilbert, Ian H.; Bickle, Quentin D. | |
| Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni. | 1-gen-2015 | Lalli C; Guidi A; Gennari N; Altamura S; Bresciani A; Ruberti G. | |
| Structural and functional characterization of the enantiomers of the antischistosomal drug oxamniquine | 1-gen-2015 | Alexander B. Taylor; Livia PicaMattoccia; Chiara M. Polcaro; Enrica Donati;Xiaohang Cao; Annalisa Basso; Alessandra Guidi; Anastasia R. Rugel; StephenP. Holloway; Timothy J. C. Anderson; P. John Hart;; Donato Cioli; PhilipT. LoVerde; | |
| Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine. | 1-gen-2015 | Taylor, A B; Picamattoccia, L; Polcaro, C M; Donati, E; Cao, X; Basso, A; Guidi, A; Rugel, A R; Holloway, S P; Anderson, T J C; Hart, P J; Cioli, D; Loverde, P T | |
| Schistosomiasis control: Praziquantel forever? | 1-gen-2014 | Cioli D.; PicaMattoccia L.; Basso A.; Guidi A. | |
| Use of Perhexiline | 1-gen-2014 | Ruberti, G; Lalli, C; Guidi, A; Bresciani, A; Gennari, N; Paonessa, G; Nizzi, E | |
| Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases | 1-gen-2012 | Paveley, Ross A.; Mansour, Nuha R.; Hallyburton, Irene; Bleicher, Leo S.; Benn, Alex E.; Mikic, Ivana; Guidi, Alessandra; Gilbert, Ian H.; Hopkins, Andrew L.; Bickle, Quentin D. | |
| Praziquantel efficacy and long-term appraisal of schistosomiasis control in Pemba Island. | 1-gen-2010 | Guidi A; Andolina C; Makame Ame S; Albonico M; Cioli D; Juma Haji H. | |
| Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni | 1-gen-2009 | PicaMattoccia L; Doenhoff MJ; Valle C; Basso A; Troiani AR; Liberti P; Festucci A; Guidi A; Cioli D |