PAOLETTI, FRANCESCA
PAOLETTI, FRANCESCA
Istituto di Cristallografia - IC - Sede Secondaria Trieste
ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity
2024 Paoletti, F.
Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2+
2023 Paoletti, Francesca; Covaceuszach, Sonia; Cassetta, Alberto; Calabrese Antonio, N N; Novak, Urban; Konarev, Petr; Grdadolnik, Joze; Lamba, Doriano; Grdadolnik Simona, Golic
Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions
2021 Paoletti, F; Merzel, F; Cassetta, A; Ogris, I; Covaceuszach, S; Grdadolnik, J; Lamba, D; Golic Grdadolnik, S
Small endogenous ligands modulation of nerve growth factor bioactivity: A structural biology overview
2021 Paoletti, F; Lamba, D
ATP binding to the Nerve Growth Factor: a molecular switch for neurotrophins signaling?
2019 Francesca Paoletti; Iza Ogris; Sonia Covaceuszach; Alberto Cassetta ; Joe Grdadolnik; Doriano Lamba; Simona Goli Grdadolnik
Insights into the Nerve Growth Factor / endogenous ligands binding mechanism.
2018 Paoletti, Francesca; Ogris, Iza; Covaceuszach, Sonia; Lamba, Doriano; Goli Grdadolnik, Simona
The binding of ATP to the Nerve Growth Factor: a new mechanism for neurotrophins signaling.
2018 Paoletti, Francesca; Ogris, Iza; Covaceuszach, Sonia; Lamba, Doriano; Goli Grdadolnik, Simona
Conformational rigidity within plasticity promotes differential target recognition of Nerve Growth Factor
2016 Paoletti, Francesca; de Chiara, Cesira; Kelly, Geoff; Covaceuszach, Sonia; Malerba, Francesca; Yan, Robert; Lamba, Doriano; Cattaneo, Antonino; Pastore, Annalisa
A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor.
2015 Paoletti, Francesca; Malerba, Francesca; Bruni Ercole, Bruno; Lamba, Doriano; Cattaneo, Antonino
Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications
2015 Francesca Malerba; Francesca Paoletti; Bruno Bruni Ercole; Serena Materazzi;Romina Nassini; Elisabetta Coppi; Riccardo Patacchini; Simona Capsoni;Doriano Lamba; Antonino Cattaneo;
The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?
2015 Covaceuszach, S; Konarev, Pv; Cassetta, A; Paoletti, F; Svergun, Di; Lamba, D; Cattaneo, A
proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither sinhly produces
2014 Arisi, Ivan; D'Onofrio, Mara; Brandi, Rossella; Malerba, Francesca; Paoletti, Francesca; Ennio Storti, Andrea; Florenzano, Fulvio; Fasulo, Luisa; Cattaneo, Antonino
NGF conformational changes in the context of proNGF: NMR structural studies
2013 Paoletti, F; Malerba, F; Kelly, G; Lamba, D; Pastore, A; Cattaneo, A
Intranasal "painless" human Nerve Growth Factors slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice
2012 Simona Capsoni ,; Sara Marinelli ; Marcello Ceci ; Domenico Vignone ; Gianluca Amato ; Francesca Malerba ,; Francesca Paoletti ; Giovanni Meli ; Alessandro Viegi ; Flaminia Pavone ; Antonino Cattaneo ,
Conformational plasticity of proNGF
2011 Paoletti, F; Malerba, F; Kelly, G; Noinville, S; Lamba, D; Cattaneo, A; Pastore, A
In vitro receptor binding properties of a painless NGF mutein, linked to Hereditary Sensory Autonomic Neuropathy type V
2010 Covaceuszach, S; Capsoni, S; Marinelli, S; Pavone, F; Ceci, M; Ugolini, G; Vignone, D; Amato, G; Paoletti, F; Lamba, D; Cattaneo, ; A,
New insights into the intrinsic structural disorder of mouse proNGF
2010 Paoletti F.; Malerba F.; Lamba D.; Pastore A.; Cattaneo A.
New insights into the intrinsic structural disorder of mouse proNGF
2010 Paoletti, F; Malerba, F; Lamba, D; Pastore, A; Cattaneo, A
Intrinsic structural disorder of mouse proNGF
2009 Paoletti, F; Covaceuszach, S; Konarev, Pv; Gonfloni, S; Malerba, F; Schwarz, E; Svergun, Di; Cattaneo, A; Lamba, D
Intrinsic structural disorder of mouse proNGF
2009 Paoletti, F; Covaceuszach, S; Konarev, Pv; Gonfloni, S; Malerba, F; Schwarz, E; Svergun, Di; Cattaneo, A; Lamba, D
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity | 1-gen-2024 | Paoletti, F. | |
| Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2+ | 1-gen-2023 | Paoletti, Francesca; Covaceuszach, Sonia; Cassetta, Alberto; Calabrese Antonio, N N; Novak, Urban; Konarev, Petr; Grdadolnik, Joze; Lamba, Doriano; Grdadolnik Simona, Golic | |
| Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions | 1-gen-2021 | Paoletti, F; Merzel, F; Cassetta, A; Ogris, I; Covaceuszach, S; Grdadolnik, J; Lamba, D; Golic Grdadolnik, S | |
| Small endogenous ligands modulation of nerve growth factor bioactivity: A structural biology overview | 1-gen-2021 | Paoletti, F; Lamba, D | |
| ATP binding to the Nerve Growth Factor: a molecular switch for neurotrophins signaling? | 1-gen-2019 | Francesca Paoletti; Iza Ogris; Sonia Covaceuszach; Alberto Cassetta ; Joe Grdadolnik; Doriano Lamba; Simona Goli Grdadolnik | |
| Insights into the Nerve Growth Factor / endogenous ligands binding mechanism. | 1-gen-2018 | Paoletti, Francesca; Ogris, Iza; Covaceuszach, Sonia; Lamba, Doriano; Goli Grdadolnik, Simona | |
| The binding of ATP to the Nerve Growth Factor: a new mechanism for neurotrophins signaling. | 1-gen-2018 | Paoletti, Francesca; Ogris, Iza; Covaceuszach, Sonia; Lamba, Doriano; Goli Grdadolnik, Simona | |
| Conformational rigidity within plasticity promotes differential target recognition of Nerve Growth Factor | 1-gen-2016 | Paoletti, Francesca; de Chiara, Cesira; Kelly, Geoff; Covaceuszach, Sonia; Malerba, Francesca; Yan, Robert; Lamba, Doriano; Cattaneo, Antonino; Pastore, Annalisa | |
| A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. | 1-gen-2015 | Paoletti, Francesca; Malerba, Francesca; Bruni Ercole, Bruno; Lamba, Doriano; Cattaneo, Antonino | |
| Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications | 1-gen-2015 | Francesca Malerba; Francesca Paoletti; Bruno Bruni Ercole; Serena Materazzi;Romina Nassini; Elisabetta Coppi; Riccardo Patacchini; Simona Capsoni;Doriano Lamba; Antonino Cattaneo; | |
| The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled? | 1-gen-2015 | Covaceuszach, S; Konarev, Pv; Cassetta, A; Paoletti, F; Svergun, Di; Lamba, D; Cattaneo, A | |
| proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither sinhly produces | 1-gen-2014 | Arisi, Ivan; D'Onofrio, Mara; Brandi, Rossella; Malerba, Francesca; Paoletti, Francesca; Ennio Storti, Andrea; Florenzano, Fulvio; Fasulo, Luisa; Cattaneo, Antonino | |
| NGF conformational changes in the context of proNGF: NMR structural studies | 1-gen-2013 | Paoletti, F; Malerba, F; Kelly, G; Lamba, D; Pastore, A; Cattaneo, A | |
| Intranasal "painless" human Nerve Growth Factors slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice | 1-gen-2012 | Simona Capsoni ,; Sara Marinelli ; Marcello Ceci ; Domenico Vignone ; Gianluca Amato ; Francesca Malerba ,; Francesca Paoletti ; Giovanni Meli ; Alessandro Viegi ; Flaminia Pavone ; Antonino Cattaneo , | |
| Conformational plasticity of proNGF | 1-gen-2011 | Paoletti, F; Malerba, F; Kelly, G; Noinville, S; Lamba, D; Cattaneo, A; Pastore, A | |
| In vitro receptor binding properties of a painless NGF mutein, linked to Hereditary Sensory Autonomic Neuropathy type V | 1-gen-2010 | Covaceuszach, S; Capsoni, S; Marinelli, S; Pavone, F; Ceci, M; Ugolini, G; Vignone, D; Amato, G; Paoletti, F; Lamba, D; Cattaneo, ; A, | |
| New insights into the intrinsic structural disorder of mouse proNGF | 1-gen-2010 | Paoletti F.; Malerba F.; Lamba D.; Pastore A.; Cattaneo A. | |
| New insights into the intrinsic structural disorder of mouse proNGF | 1-gen-2010 | Paoletti, F; Malerba, F; Lamba, D; Pastore, A; Cattaneo, A | |
| Intrinsic structural disorder of mouse proNGF | 1-gen-2009 | Paoletti, F; Covaceuszach, S; Konarev, Pv; Gonfloni, S; Malerba, F; Schwarz, E; Svergun, Di; Cattaneo, A; Lamba, D | |
| Intrinsic structural disorder of mouse proNGF | 1-gen-2009 | Paoletti, F; Covaceuszach, S; Konarev, Pv; Gonfloni, S; Malerba, F; Schwarz, E; Svergun, Di; Cattaneo, A; Lamba, D |