TOSATTO, LAURA
TOSATTO, LAURA
Istituto di Biofisica - IBF - Sede Secondaria Milano
The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens
2025 Falconieri, A.; Boarolo, G.; Boschelle, C.; Spagnolli, G.; Marchioretti, C.; Zuccaro, E.; Palazzolo, I.; Tosatto, L.; Hegazy, A. K. O.; Rosati, J.; Fischbeck, K.; Basso, M.; Liedtke, H. C.; Gomez-Mestre, I.; Dalla Valle, L.; Biasini, E.; Faccioli, P.; Grapputo, A.; Pennuto, M.
Fluorescence labeling methods influence the aggregation process of α-syn in vitro differently
2023 Jadavi, S.; Dante, S.; Civiero, L.; Sandre, M.; Bubacco, L.; Tosatto, L.; Bianchini, P.; Canale, C.; Diaspro, A.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
2023 Prakasam, R.; Bonadiman, A.; Andreotti, R.; Zuccaro, E.; Dalfovo, D.; Marchioretti, C.; Tripathy, D.; Petris, G.; Anderson, E. N.; Migazzi, A.; Tosatto, L.; Cereseto, A.; Battaglioli, E.; Soraru, G.; Lim, W. F.; Rinaldi, C.; Sambataro, F.; Pourshafie, N.; Grunseich, C.; Romanel, A.; Pandey, U. B.; Contestabile, A.; Ronzitti, G.; Basso, M.; Pennuto, M.
Pathological structural conversion of alpha-synuclein at the mitochondria induces neuronal toxicity
2022 Choi Minee, L; Chappard, Alexandre; Singh Bhanu, P; Maclachlan, Catherine; Rodrigues, Margarida; Fedotova, Evgenia; Berezhnov, V Alexey; De, Suman; Peddie, Chris; Athauda, Dilan; Virdi Gurvir, S; Zhang, Weijia; Evans James, R; Wernick, Anna; Zanjani Zeinab, Shadman; Angelova Plamena, R; Esteras, Noemi; Vinikurov, Andrey; Morris, Katie; Jeacock, Kiani; Tosatto, Laura; Little, Daniel; Gissen, Paul; Clarke David, J; Kunath, Tilo; Collinson, Lucy; Klenerman, David; Abramov Andrey, Y; Horrocks Mathew, H; Gandhi, Sonia
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
2021 Migazzi, A.; Scaramuzzino, C.; Anderson, E. N.; Tripathy, D.; Hernandez, I. H.; Grant, R. A.; Roccuzzo, M.; Tosatto, L.; Virlogeux, A.; Zuccato, C.; Caricasole, A.; Ratovitski, T.; Ross, C. A.; Pandey, U. B.; Lucas, J. J.; Saudou, F.; Pennuto, M.; Basso, M.
Pharmacological inactivation of the prion protein by targeting a folding intermediate
2021 Spagnolli, G; Massignan, T; Astolfi, A; Biggi, S; Rigoli, M; Brunelli, P; Libergoli, M; Ianeselli, A; Orioli, S; Boldrini, A; Terruzzi, L; Bonaldo, V; Maietta, G; Lorenzo, Nl; Fernandez, Lc; Codeseira, Yb; Tosatto, L; Linsenmeier, L; Vignoli, B; Petris, G; Gasparotto, D; Pennuto, M; Guella, G; Canossa, M; Altmeppen, Hc; Lolli, G; Biressi, S; Pastor, Mm; Requena, Jr; Mancini, I; Barreca, Ml; Faccioli, P; Biasini, E
ClC-2-like Chloride Current Alterations in a Cell Model of Spinal and Bulbar Muscular Atrophy, a Polyglutamine Disease
2020 Martinezrojas, Va; Jimenezgarduno, Am; Michelatti, D; Tosatto, L; Marchioretto, M; Arosio, D; Basso, M; Pennuto, M; Musio, C
Alteration and amelioration of ionic currents in motoneuron-derived cellsmodelling spinal and bulbar muscular atrophy (SBMA)
2017 Jimenez Gardu no, Am; Juarezhernandez, Lj; Polanco, Mj; Tosattol, ; Michelatti, D; Arosio, D; Basso, M; Pennuto, M; Musio, C
Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA.
2017 Jiménez Garduño AM; JuárezHernández LJ; Polanco MJ; Tosatto L; Michelatti D; Arosio D; Basso M; Pennuto M; Musio C
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping
2016 Bongiovanni, M. N.; Godet, J.; Horrocks, M. H.; Tosatto, L.; Carr, A. R.; Wirthensohn, D. C.; Ranasinghe, R. T.; Lee, J. -E.; Ponjavic, A.; Fritz, J. V.; Dobson, C. M.; Klenerman, D.; Lee, S. F.
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids
2016 Horrocks, Mathew H.; Lee, Steven F.; Gandhi, Sonia; Magdalinou, Nadia K.; Chen, Serene W.; Devine, Michael J.; Tosatto, Laura; Kjaergaard, Magnus; Beckwith, Joseph S.; Zetterberg, Henrik; Iljina, Marija; Cremades, Nunilo; Dobson, Christopher M.; Wood, Nicholas W.; Klenerman, David
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of alpha-Synuclein Oligomers
2015 Horrocks M.H.; Tosatto L.; Dear A.J.; Garcia G.A.; Iljina M.; Cremades N.; Dalla Serra M.; Knowles T.P.J.; Dobson C.M.; Klenerman D.
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants
2015 Tosatto, Laura; Tosatto, Laura; Horrocks Mathew, H; Dear Alexander, J; Knowles Tuomas, Pj; Dalla Serra, Mauro; Cremades, Nunilo; Cremades, Nunilo; Dobson Christopher, M; Klenerman, David
The chaperone-like protein 14-3-3 eta interacts with human alpha-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing alpha-synuclein cellular toxicity
2014 Plotegher, Nicoletta; Kumar, Dhruv; Tessari, Isabella; Brucale, Marco; Munari, Francesca; Tosatto, Laura; Belluzzi, Elisa; Greggio, Elisa; Bisaglia, Marco; Capaldi, Stefano; Aioanei, Daniel; Mammi, Stefano; Monaco Hugo, L; Samori, Bruno; Bubacco, Luigi
Alpha-synuclein pore forming activity upon membrane association
2012 Tosatto, L; Andrighetti, Ao; Plotegher, N; Antonini, V; Tessari, I; Ricci, L; Bubacco, ; Dalla Serra, M
Covalent alpha-Synuclein Dimers: Chemico-Physical and Aggregation Properties
2012 Pivato, Micaela; De Franceschi, Giorgia; Tosatto, Laura; Frare, Erica; Kumar, Dhruv; Aioanei, Daniel; Brucale, Marco; Tessari, Isabella; Bisaglia, Marco; Samori, Bruno; de laureto, Patrizia Polverino; Bubacco, Luigi
Investigations on alpha-synuclein pore forming properties
2011 Tosatto, L.; Andrighetti, A. O.; Cronin, B.; Tessari, I.; Plotegher, N.; Ganzinger, K.; McColl, J.; Antonini, V.; Bubacco, L.; Klenerman, D.; Wallace, M.; Dalla Serra, M.
Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers
2009 Brucale, M; Sandal, M; Di Maio, S; Rampioni, A; Tessari, I; Tosatto, L; Bisaglia, M; Bubacco, L; Samori, B
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens | 1-gen-2025 | Falconieri, A.; Boarolo, G.; Boschelle, C.; Spagnolli, G.; Marchioretti, C.; Zuccaro, E.; Palazzolo, I.; Tosatto, L.; Hegazy, A. K. O.; Rosati, J.; Fischbeck, K.; Basso, M.; Liedtke, H. C.; Gomez-Mestre, I.; Dalla Valle, L.; Biasini, E.; Faccioli, P.; Grapputo, A.; Pennuto, M. | |
| Fluorescence labeling methods influence the aggregation process of α-syn in vitro differently | 1-gen-2023 | Jadavi, S.; Dante, S.; Civiero, L.; Sandre, M.; Bubacco, L.; Tosatto, L.; Bianchini, P.; Canale, C.; Diaspro, A. | |
| LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice | 1-gen-2023 | Prakasam, R.; Bonadiman, A.; Andreotti, R.; Zuccaro, E.; Dalfovo, D.; Marchioretti, C.; Tripathy, D.; Petris, G.; Anderson, E. N.; Migazzi, A.; Tosatto, L.; Cereseto, A.; Battaglioli, E.; Soraru, G.; Lim, W. F.; Rinaldi, C.; Sambataro, F.; Pourshafie, N.; Grunseich, C.; Romanel, A.; Pandey, U. B.; Contestabile, A.; Ronzitti, G.; Basso, M.; Pennuto, M. | |
| Pathological structural conversion of alpha-synuclein at the mitochondria induces neuronal toxicity | 1-gen-2022 | Choi Minee, L; Chappard, Alexandre; Singh Bhanu, P; Maclachlan, Catherine; Rodrigues, Margarida; Fedotova, Evgenia; Berezhnov, V Alexey; De, Suman; Peddie, Chris; Athauda, Dilan; Virdi Gurvir, S; Zhang, Weijia; Evans James, R; Wernick, Anna; Zanjani Zeinab, Shadman; Angelova Plamena, R; Esteras, Noemi; Vinikurov, Andrey; Morris, Katie; Jeacock, Kiani; Tosatto, Laura; Little, Daniel; Gissen, Paul; Clarke David, J; Kunath, Tilo; Collinson, Lucy; Klenerman, David; Abramov Andrey, Y; Horrocks Mathew, H; Gandhi, Sonia | |
| Huntingtin-mediated axonal transport requires arginine methylation by PRMT6 | 1-gen-2021 | Migazzi, A.; Scaramuzzino, C.; Anderson, E. N.; Tripathy, D.; Hernandez, I. H.; Grant, R. A.; Roccuzzo, M.; Tosatto, L.; Virlogeux, A.; Zuccato, C.; Caricasole, A.; Ratovitski, T.; Ross, C. A.; Pandey, U. B.; Lucas, J. J.; Saudou, F.; Pennuto, M.; Basso, M. | |
| Pharmacological inactivation of the prion protein by targeting a folding intermediate | 1-gen-2021 | Spagnolli, G; Massignan, T; Astolfi, A; Biggi, S; Rigoli, M; Brunelli, P; Libergoli, M; Ianeselli, A; Orioli, S; Boldrini, A; Terruzzi, L; Bonaldo, V; Maietta, G; Lorenzo, Nl; Fernandez, Lc; Codeseira, Yb; Tosatto, L; Linsenmeier, L; Vignoli, B; Petris, G; Gasparotto, D; Pennuto, M; Guella, G; Canossa, M; Altmeppen, Hc; Lolli, G; Biressi, S; Pastor, Mm; Requena, Jr; Mancini, I; Barreca, Ml; Faccioli, P; Biasini, E | |
| ClC-2-like Chloride Current Alterations in a Cell Model of Spinal and Bulbar Muscular Atrophy, a Polyglutamine Disease | 1-gen-2020 | Martinezrojas, Va; Jimenezgarduno, Am; Michelatti, D; Tosatto, L; Marchioretto, M; Arosio, D; Basso, M; Pennuto, M; Musio, C | |
| Alteration and amelioration of ionic currents in motoneuron-derived cellsmodelling spinal and bulbar muscular atrophy (SBMA) | 1-gen-2017 | Jimenez Gardu no, Am; Juarezhernandez, Lj; Polanco, Mj; Tosattol, ; Michelatti, D; Arosio, D; Basso, M; Pennuto, M; Musio, C | |
| Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA. | 1-gen-2017 | Jiménez Garduño AM; JuárezHernández LJ; Polanco MJ; Tosatto L; Michelatti D; Arosio D; Basso M; Pennuto M; Musio C | |
| Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping | 1-gen-2016 | Bongiovanni, M. N.; Godet, J.; Horrocks, M. H.; Tosatto, L.; Carr, A. R.; Wirthensohn, D. C.; Ranasinghe, R. T.; Lee, J. -E.; Ponjavic, A.; Fritz, J. V.; Dobson, C. M.; Klenerman, D.; Lee, S. F. | |
| Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids | 1-gen-2016 | Horrocks, Mathew H.; Lee, Steven F.; Gandhi, Sonia; Magdalinou, Nadia K.; Chen, Serene W.; Devine, Michael J.; Tosatto, Laura; Kjaergaard, Magnus; Beckwith, Joseph S.; Zetterberg, Henrik; Iljina, Marija; Cremades, Nunilo; Dobson, Christopher M.; Wood, Nicholas W.; Klenerman, David | |
| Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of alpha-Synuclein Oligomers | 1-gen-2015 | Horrocks M.H.; Tosatto L.; Dear A.J.; Garcia G.A.; Iljina M.; Cremades N.; Dalla Serra M.; Knowles T.P.J.; Dobson C.M.; Klenerman D. | |
| Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants | 1-gen-2015 | Tosatto, Laura; Tosatto, Laura; Horrocks Mathew, H; Dear Alexander, J; Knowles Tuomas, Pj; Dalla Serra, Mauro; Cremades, Nunilo; Cremades, Nunilo; Dobson Christopher, M; Klenerman, David | |
| The chaperone-like protein 14-3-3 eta interacts with human alpha-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing alpha-synuclein cellular toxicity | 1-gen-2014 | Plotegher, Nicoletta; Kumar, Dhruv; Tessari, Isabella; Brucale, Marco; Munari, Francesca; Tosatto, Laura; Belluzzi, Elisa; Greggio, Elisa; Bisaglia, Marco; Capaldi, Stefano; Aioanei, Daniel; Mammi, Stefano; Monaco Hugo, L; Samori, Bruno; Bubacco, Luigi | |
| Alpha-synuclein pore forming activity upon membrane association | 1-gen-2012 | Tosatto, L; Andrighetti, Ao; Plotegher, N; Antonini, V; Tessari, I; Ricci, L; Bubacco, ; Dalla Serra, M | |
| Covalent alpha-Synuclein Dimers: Chemico-Physical and Aggregation Properties | 1-gen-2012 | Pivato, Micaela; De Franceschi, Giorgia; Tosatto, Laura; Frare, Erica; Kumar, Dhruv; Aioanei, Daniel; Brucale, Marco; Tessari, Isabella; Bisaglia, Marco; Samori, Bruno; de laureto, Patrizia Polverino; Bubacco, Luigi | |
| Investigations on alpha-synuclein pore forming properties | 1-gen-2011 | Tosatto, L.; Andrighetti, A. O.; Cronin, B.; Tessari, I.; Plotegher, N.; Ganzinger, K.; McColl, J.; Antonini, V.; Bubacco, L.; Klenerman, D.; Wallace, M.; Dalla Serra, M. | |
| Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers | 1-gen-2009 | Brucale, M; Sandal, M; Di Maio, S; Rampioni, A; Tessari, I; Tosatto, L; Bisaglia, M; Bubacco, L; Samori, B |