SIMBULA, MICHELA
SIMBULA, MICHELA
Istituto di Ricerca Genetica e Biomedica - IRGB
Drugs Repurposing of Molecules Modulating Human Delta Globin Gene Expression via a Model of Transgenic Foetal Liver Cells: Implications for Beta-Hemoglobinopathy Therapeutics
2025 Simbula, Michela; Manchinu, Maria Francesca; Olla, Stefania; Congiu, Michela; Vaccargiu, Simona; Caria, Cristian Antonio; Poddie, Daniela; Ristaldi, Maria Serafina
TDP-43 Regulates Rab4 Levels to Support Synaptic Vesicle Recycling and Neuromuscular Connectivity in Drosophila and Human ALS Models
2025 Gbadamosi, Monsurat; Romano, Giulia; Simbula, Michela; Canarutto, Giulia; Ottoboni, Linda; Corti, Stefania; Fabian Feiguin, And
miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation
2023 Simbula, Michela; Manchinu, MARIA FRANCESCA; Mingoia, Maura; Pala, Mauro; Asunis, Isadora; Caria Cristian, Antonio; Perseu, Lucia; Shah, Manan; Crossley, Merlin; Moi, Paolo; Ristaldi, MARIA SERAFINA
Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait
2023 Trucas, Marcello; Burattini, Sabrina; Porcu, Susanna; Simbula, Michela; Ristaldi, MARIA SERAFINA; Kowalik Marta, Anna; Serra Maria, Pina; Gobbi, Pietro; Battistelli, Michela; Perra, Andrea; Quartu, Marina
Delta-globin gene expression improves sickle cell disease in a humanised mouse model
2021 Porcu, Susanna; Simbula, Michela; Marongiu, MARIA FRANCA; Perra, Andrea; Poddie, Daniela; Perseu, Lucia; A Kowalik, Marta; Littera, Roberto; Barella, Susanna; A Caria, Cristian; R Demartis, Franca; Ristaldi, MARIA SERAFINA
Delta-Globin Gene Expression Is Enhanced in vivo by Interferon Type I
2020 Manchinu, MARIA FRANCESCA; Simbula, Michela; Caria, CRISTIAN ANTONIO; Musu, Ester; Perseu, Lucia; Porcu, Susanna; Steri, Maristella; Poddie, Daniela; Frau, Jessica; Cocco, Eleonora; Manunza, Laura; Barella, Susanna; Ristaldi, MARIA SERAFINA
Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice
2017 Manchinu, MARIA FRANCESCA; Brancia, Carla; Caria, CRISTIAN ANTONIO; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, MARIA SERAFINA
In vivo activation of the human delta-globin gene: the therapeutic potential in beta-thalassemic mice
2013 Manchinu, Mf; Marongiu, Mf; Poddie, D; Casu, C; Latini, V; Simbula, M; Galanello, R; Moi, P; Cao, A; Porcu, S; Ristaldi, Ms
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Drugs Repurposing of Molecules Modulating Human Delta Globin Gene Expression via a Model of Transgenic Foetal Liver Cells: Implications for Beta-Hemoglobinopathy Therapeutics | 1-gen-2025 | Simbula, Michela; Manchinu, Maria Francesca; Olla, Stefania; Congiu, Michela; Vaccargiu, Simona; Caria, Cristian Antonio; Poddie, Daniela; Ristaldi, Maria Serafina | |
| TDP-43 Regulates Rab4 Levels to Support Synaptic Vesicle Recycling and Neuromuscular Connectivity in Drosophila and Human ALS Models | 1-gen-2025 | Gbadamosi, Monsurat; Romano, Giulia; Simbula, Michela; Canarutto, Giulia; Ottoboni, Linda; Corti, Stefania; Fabian Feiguin, And | |
| miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation | 1-gen-2023 | Simbula, Michela; Manchinu, MARIA FRANCESCA; Mingoia, Maura; Pala, Mauro; Asunis, Isadora; Caria Cristian, Antonio; Perseu, Lucia; Shah, Manan; Crossley, Merlin; Moi, Paolo; Ristaldi, MARIA SERAFINA | |
| Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait | 1-gen-2023 | Trucas, Marcello; Burattini, Sabrina; Porcu, Susanna; Simbula, Michela; Ristaldi, MARIA SERAFINA; Kowalik Marta, Anna; Serra Maria, Pina; Gobbi, Pietro; Battistelli, Michela; Perra, Andrea; Quartu, Marina | |
| Delta-globin gene expression improves sickle cell disease in a humanised mouse model | 1-gen-2021 | Porcu, Susanna; Simbula, Michela; Marongiu, MARIA FRANCA; Perra, Andrea; Poddie, Daniela; Perseu, Lucia; A Kowalik, Marta; Littera, Roberto; Barella, Susanna; A Caria, Cristian; R Demartis, Franca; Ristaldi, MARIA SERAFINA | |
| Delta-Globin Gene Expression Is Enhanced in vivo by Interferon Type I | 1-gen-2020 | Manchinu, MARIA FRANCESCA; Simbula, Michela; Caria, CRISTIAN ANTONIO; Musu, Ester; Perseu, Lucia; Porcu, Susanna; Steri, Maristella; Poddie, Daniela; Frau, Jessica; Cocco, Eleonora; Manunza, Laura; Barella, Susanna; Ristaldi, MARIA SERAFINA | |
| Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice | 1-gen-2017 | Manchinu, MARIA FRANCESCA; Brancia, Carla; Caria, CRISTIAN ANTONIO; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, MARIA SERAFINA | |
| In vivo activation of the human delta-globin gene: the therapeutic potential in beta-thalassemic mice | 1-gen-2013 | Manchinu, Mf; Marongiu, Mf; Poddie, D; Casu, C; Latini, V; Simbula, M; Galanello, R; Moi, P; Cao, A; Porcu, S; Ristaldi, Ms |