SILVESTRI, ILARIA
SILVESTRI, ILARIA
Istituto di Cristallografia - IC
Structure-based identification of a non-covalent thioredoxin reductase inhibitor with proven ADMET suitability
2025 Lamanna, G.; Augello, G.; Ronga, L.; Tesauro, D.; Silvestri, I.; Azzolina, A.; Cervello, M.; Mangiatordi, G. F.; Saviano, M.
Targeting the conserved active site of splicing machines with specific and selective small molecule modulators
2024 Silvestri, I.; Manigrasso, J.; Andreani, A.; Brindani, N.; Mas, C.; Reiser, J. -B.; Vidossich, P.; Martino, G.; Mccarthy, A. A.; De Vivo, M.; Marcia, M.
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
2022 Fata, Francesca; Gencheva, Radosveta; Cheng, Qing; Lullo, Rachel; Ardini, Matteo; Silvestri, Ilaria; Gabriele, Federica; Ippoliti, Rodolfo; Bulman, Christina A.; Sakanari, Judy A.; Williams, David L.; Arn('(e))r, Elias S. J.; Angelucci, Francesco
Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments
2021 Fata, F; Silvestri, I; Ardini, M; Ippoliti, R; Di Leandro, L; Demitri, N; Polentarutti, M; Di Matteo, A; Lyu, H; Thatcher, Grj; Petukhov, Pa; Williams, Dl; Angelucci, F
The folding and aggregation properties of a single KH-domain protein: Ribosome binding factor A (RbfA) from Pseudomonas aeruginosa
2021 Santorelli, D; Rocchio, S; Fata, F; Silvestri, I; Angelucci, F; Imperi, F; Marasco, D; Diaferia, C; Gigli, L; Demitri, N; Federici, L; Di Matteo, A; Travagliniallocatelli, C
A ring-shaped protein clusters gold nanoparticles acting as molecular scaffold for plasmonic surfaces
2020 Ardini, M.; Huang, J. -A.; Caprettini, V.; De Angelis, F.; Fata, F.; Silvestri, I.; Cimini, A.; Giansanti, F.; Angelucci, F.; Ippoliti, R.
Ectopic suicide inhibition of thioredoxin glutathione reductase
2020 Silvestri, I.; Lyu, H.; Fata, F.; Banta, P. R.; Mattei, B.; Ippoliti, R.; Bellelli, A.; Pitari, G.; Ardini, M.; Petukhova, V.; Thatcher, G. R. J.; Petukhov, P. A.; Williams, D. L.; Angelucci, F.
Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "doorstop" for NADPH Entry
2018 Silvestri, I.; Lyu, H.; Fata, F.; Boumis, G.; Miele, A. E.; Ardini, M.; Ippoliti, R.; Bellelli, A.; Jadhav, A.; Lea, W. A.; Simeonov, A.; Cheng, Q.; Arner, E. S. J.; Thatcher, G. R. J.; Petukhov, P. A.; Williams, D. L.; Angelucci, F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Structure-based identification of a non-covalent thioredoxin reductase inhibitor with proven ADMET suitability | 1-gen-2025 | Lamanna, G.; Augello, G.; Ronga, L.; Tesauro, D.; Silvestri, I.; Azzolina, A.; Cervello, M.; Mangiatordi, G. F.; Saviano, M. | |
| Targeting the conserved active site of splicing machines with specific and selective small molecule modulators | 1-gen-2024 | Silvestri, I.; Manigrasso, J.; Andreani, A.; Brindani, N.; Mas, C.; Reiser, J. -B.; Vidossich, P.; Martino, G.; Mccarthy, A. A.; De Vivo, M.; Marcia, M. | |
| Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus | 1-gen-2022 | Fata, Francesca; Gencheva, Radosveta; Cheng, Qing; Lullo, Rachel; Ardini, Matteo; Silvestri, Ilaria; Gabriele, Federica; Ippoliti, Rodolfo; Bulman, Christina A.; Sakanari, Judy A.; Williams, David L.; Arn('(e))r, Elias S. J.; Angelucci, Francesco | |
| Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments | 1-gen-2021 | Fata, F; Silvestri, I; Ardini, M; Ippoliti, R; Di Leandro, L; Demitri, N; Polentarutti, M; Di Matteo, A; Lyu, H; Thatcher, Grj; Petukhov, Pa; Williams, Dl; Angelucci, F | |
| The folding and aggregation properties of a single KH-domain protein: Ribosome binding factor A (RbfA) from Pseudomonas aeruginosa | 1-gen-2021 | Santorelli, D; Rocchio, S; Fata, F; Silvestri, I; Angelucci, F; Imperi, F; Marasco, D; Diaferia, C; Gigli, L; Demitri, N; Federici, L; Di Matteo, A; Travagliniallocatelli, C | |
| A ring-shaped protein clusters gold nanoparticles acting as molecular scaffold for plasmonic surfaces | 1-gen-2020 | Ardini, M.; Huang, J. -A.; Caprettini, V.; De Angelis, F.; Fata, F.; Silvestri, I.; Cimini, A.; Giansanti, F.; Angelucci, F.; Ippoliti, R. | |
| Ectopic suicide inhibition of thioredoxin glutathione reductase | 1-gen-2020 | Silvestri, I.; Lyu, H.; Fata, F.; Banta, P. R.; Mattei, B.; Ippoliti, R.; Bellelli, A.; Pitari, G.; Ardini, M.; Petukhova, V.; Thatcher, G. R. J.; Petukhov, P. A.; Williams, D. L.; Angelucci, F. | |
| Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "doorstop" for NADPH Entry | 1-gen-2018 | Silvestri, I.; Lyu, H.; Fata, F.; Boumis, G.; Miele, A. E.; Ardini, M.; Ippoliti, R.; Bellelli, A.; Jadhav, A.; Lea, W. A.; Simeonov, A.; Cheng, Q.; Arner, E. S. J.; Thatcher, G. R. J.; Petukhov, P. A.; Williams, D. L.; Angelucci, F. |