SANTORO, ANNA MARIA
SANTORO, ANNA MARIA
Istituto di Cristallografia - IC
Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging
2023 D'Urso, Alessandro; Purrello, Roberto; Cunsolo, Alessandra; Milardi, Danilo; Fattorusso, Caterina; Persico, Marco; Gaczynska, Maria; Osmulski Pawel, A; Santoro, ANNA MARIA
Targeting immunoproteasome in neurodegeneration: A glance to the future
2023 Tundo, Gr; Cascio, P; Milardi, D; Santoro, Am; Graziani, G; Lacal, Pm; Bocedi, A; Oddone, F; Parravano, M; Coletta, A; Coletta, M; Sbardella, D
Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813))
2022 Persico, Marco; Garcíaviñuales, Sara; Santoro, ANNA MARIA; Lanza, Valeria; Tundo Grazia, Raffaella; Sbardella, Diego; Coletta, Massimiliano; Romanucci, Valeria; Zarrelli, Armando; Di Fabio, Giovanni; Fattorusso, Caterina; Milardi, Danilo
Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug
2022 Tundo G.R.; Sbardella D.; Oddone F.; Grasso G.; Marini S.; Atzori M.G.; Santoro A.M.; Milardi D.; Bellia F.; Macari G.; Graziani G.; Polticelli F.; Cascio P.; Parravano M.; Coletta M.
Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution
2022 Persico, Marco; Santoro, Anna Maria; D'urso, Alessandro; Milardi, Danilo; Purrello, Roberto; Cunsolo, Alessandra; Gobbo, Marina; Fattorusso, Roberto; Diana, Donatella; Stefanelli, Manuela; Tundo, Grazia R.; Sbardella, Diego; Coletta, Massimo; Fattorusso, Caterina
Silybins are stereospecific regulators of the 20S proteasome
2022 Persico, M; Garciavinuales, S; Santoro, Am; Lanza, V; Tundo, Gr; Sbardella, D; Coletta, M; Romanucci, V; Zarrelli, A; Di Fabio, G; Fattorusso, C; Milardi, D
Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions
2022 Garciavinuales, S; Ilie, Im; Santoro, Am; Romanucci, V; Zarrelli, A; Di Fabio, G; Caflisch, A; Milardi, D
The interplay between lipid and A? amyloid homeostasis in Alzheimer's Disease: risk factors and therapeutic opportunities
2021 GarciaVinuales S.; Sciacca M.F.M.; Lanza V.; Santoro A.M.; Grasso G.; Tundo G.R.; Sbardella D.; Coletta M.; Grasso G.; La Rosa C.; Milardi D.
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States
2020 Santoro, Anna Maria; D'Urso, Alessandro; Cunsolo, Alessandra; Milardi, Danilo; Purrello, Roberto; Sbardella, Diego; Tundo, Grazia R.; Diana, Donatella; Fattorusso, Roberto; Di Dato, Antonio; Paladino, Antonella; Persico, Marco; Coletta, Massimo; Fattorusso, Caterina
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations
2020 Sbardella, Diego; Tundo, Grazia Raffaella; Cunsolo, Vincenzo; Grasso, Giuseppe; Cascella, Raffaella; Caputo, Valerio; Santoro, Anna Maria; Milardi, Danilo; Pecorelli, Alessandra; Ciaccio, Chiara; Di Pierro, Donato; Leoncini, Silvia; Campagnolo, Luisa; Pironi, Virginia; Oddone, Francesco; Manni, Priscilla; Foti, Salvatore; Giardina, Emiliano; De Felice, Claudio; Hayek, Joussef; Curatolo, Paolo; Galasso, Cinzia; Valacchi, Giuseppe; Coletta, Massimiliano; Graziani, Grazia; Marini, Stefano
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from ?-Amyloid Toxicity
2020 Santoro, Am; Lanza, V; Bellia, F; Sbardella, D; Tundo, Gr; Cannizzo, A; Grasso, G; Arizzi, M; Nicoletti, Vg; Alcaro, S; Costa, G; Pietropaolo, A; Malgieri, G; D'Abrosca, G; Fattorusso, R; Garciavinuales, S; Ahmed, Imm; Coletta, M; Milardi, D
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells
2020 Zimbone, Stefania; Santoro, Anna M.; La Mendola, Diego; Giacomelli, Chiara; Trincavelli, Maria L.; Tomasello, Marianna F.; Milardi, Danilo; GarcíaViñuales, Sara; Sciacca, Michele F.M.; Martini, Claudia; Grasso, Giulia
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
2020 Tundo, G R; Sbardella, D; Santoro, A M; Coletta, A; Oddone, F; Grasso, G; Milardi, D; Lacal, P M; Marini, S; Purrello, R; Graziani, G; Coletta, M
The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine-Proline-Rich Peptide
2020 Santoro, ANNA MARIA; Zimbone, Stefania; Magri, Antonio; La Mendola, Diego; Grasso, Giulia
Peptides derived from the histidine-proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties
2018 Magrì, Antonio; Grasso, Giulia; Corti, Federico; Finetti, Federica; Greco, Valentina; Santoro, Anna Maria; Sciuto, Sebastiano; La Mendola, Diego; Morbidelli, Lucia; Rizzarelli, Enrico
Peptides derived from the histidine-proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties
2018 Antonio Magri; Giulia Grasso; Federico Corti; Federica Finetti; Valentina Greco; Anna Maria Santoro; Sebastiano Sciuto; Diego La Mendola; Lucia Morbidelli; Enrico Rizzarelli
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S
2018 Sbardella, Diego; Tundo Grazia, R; Coletta, Andrea; Marcoux, Julien; Koufogeorgou Efthymia, Ioanna; Ciaccio, Chiara; Santoro Anna, M; Milardi, Danilo; Grasso, Giuseppe; Cozza, Paola; Bousquetdubouch, Mariepierre; Marini, Stefano; Coletta, Massimo
Electrostatic Map of Proteasome ?-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding
2017 Dato, Ad; Cunsolo, A; Persico, M; Santoro, Am; D'Urso, A; Milardi, D; Purrello, R; Stefanelli, M; Paolesse, R; Tundo, Gr; Sbardella, D; Fattorusso, C; Coletta, M
The double faced role of copper in A beta homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration
2017 Grasso, Giuseppe; Santoro, ANNA MARIA; Lanza, Valeria; Sbardella, Diego; Tundo Grazia, Raffaella; Ciaccio, Chiara; Marini, Stefano; Coletta, Massimo; Milardi, Danilo
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study
2016 Anna Maria Santoro; Irene Monaco; Francesco Attanasio; Valeria Lanza;Giuseppe Pappalardo; Marianna Flora Tomasello; Alessandra Cunsolo; Enrico Rizzarelli;Ada De Luigi; Mario Salmona;Danilo Milardi
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging | 1-gen-2023 | D'Urso, Alessandro; Purrello, Roberto; Cunsolo, Alessandra; Milardi, Danilo; Fattorusso, Caterina; Persico, Marco; Gaczynska, Maria; Osmulski Pawel, A; Santoro, ANNA MARIA | |
| Targeting immunoproteasome in neurodegeneration: A glance to the future | 1-gen-2023 | Tundo, Gr; Cascio, P; Milardi, D; Santoro, Am; Graziani, G; Lacal, Pm; Bocedi, A; Oddone, F; Parravano, M; Coletta, A; Coletta, M; Sbardella, D | |
| Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) | 1-gen-2022 | Persico, Marco; Garcíaviñuales, Sara; Santoro, ANNA MARIA; Lanza, Valeria; Tundo Grazia, Raffaella; Sbardella, Diego; Coletta, Massimiliano; Romanucci, Valeria; Zarrelli, Armando; Di Fabio, Giovanni; Fattorusso, Caterina; Milardi, Danilo | |
| Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug | 1-gen-2022 | Tundo G.R.; Sbardella D.; Oddone F.; Grasso G.; Marini S.; Atzori M.G.; Santoro A.M.; Milardi D.; Bellia F.; Macari G.; Graziani G.; Polticelli F.; Cascio P.; Parravano M.; Coletta M. | |
| Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution | 1-gen-2022 | Persico, Marco; Santoro, Anna Maria; D'urso, Alessandro; Milardi, Danilo; Purrello, Roberto; Cunsolo, Alessandra; Gobbo, Marina; Fattorusso, Roberto; Diana, Donatella; Stefanelli, Manuela; Tundo, Grazia R.; Sbardella, Diego; Coletta, Massimo; Fattorusso, Caterina | |
| Silybins are stereospecific regulators of the 20S proteasome | 1-gen-2022 | Persico, M; Garciavinuales, S; Santoro, Am; Lanza, V; Tundo, Gr; Sbardella, D; Coletta, M; Romanucci, V; Zarrelli, A; Di Fabio, G; Fattorusso, C; Milardi, D | |
| Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions | 1-gen-2022 | Garciavinuales, S; Ilie, Im; Santoro, Am; Romanucci, V; Zarrelli, A; Di Fabio, G; Caflisch, A; Milardi, D | |
| The interplay between lipid and A? amyloid homeostasis in Alzheimer's Disease: risk factors and therapeutic opportunities | 1-gen-2021 | GarciaVinuales S.; Sciacca M.F.M.; Lanza V.; Santoro A.M.; Grasso G.; Tundo G.R.; Sbardella D.; Coletta M.; Grasso G.; La Rosa C.; Milardi D. | |
| Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States | 1-gen-2020 | Santoro, Anna Maria; D'Urso, Alessandro; Cunsolo, Alessandra; Milardi, Danilo; Purrello, Roberto; Sbardella, Diego; Tundo, Grazia R.; Diana, Donatella; Fattorusso, Roberto; Di Dato, Antonio; Paladino, Antonella; Persico, Marco; Coletta, Massimo; Fattorusso, Caterina | |
| Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations | 1-gen-2020 | Sbardella, Diego; Tundo, Grazia Raffaella; Cunsolo, Vincenzo; Grasso, Giuseppe; Cascella, Raffaella; Caputo, Valerio; Santoro, Anna Maria; Milardi, Danilo; Pecorelli, Alessandra; Ciaccio, Chiara; Di Pierro, Donato; Leoncini, Silvia; Campagnolo, Luisa; Pironi, Virginia; Oddone, Francesco; Manni, Priscilla; Foti, Salvatore; Giardina, Emiliano; De Felice, Claudio; Hayek, Joussef; Curatolo, Paolo; Galasso, Cinzia; Valacchi, Giuseppe; Coletta, Massimiliano; Graziani, Grazia; Marini, Stefano | |
| Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from ?-Amyloid Toxicity | 1-gen-2020 | Santoro, Am; Lanza, V; Bellia, F; Sbardella, D; Tundo, Gr; Cannizzo, A; Grasso, G; Arizzi, M; Nicoletti, Vg; Alcaro, S; Costa, G; Pietropaolo, A; Malgieri, G; D'Abrosca, G; Fattorusso, R; Garciavinuales, S; Ahmed, Imm; Coletta, M; Milardi, D | |
| The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells | 1-gen-2020 | Zimbone, Stefania; Santoro, Anna M.; La Mendola, Diego; Giacomelli, Chiara; Trincavelli, Maria L.; Tomasello, Marianna F.; Milardi, Danilo; GarcíaViñuales, Sara; Sciacca, Michele F.M.; Martini, Claudia; Grasso, Giulia | |
| The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges | 1-gen-2020 | Tundo, G R; Sbardella, D; Santoro, A M; Coletta, A; Oddone, F; Grasso, G; Milardi, D; Lacal, P M; Marini, S; Purrello, R; Graziani, G; Coletta, M | |
| The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine-Proline-Rich Peptide | 1-gen-2020 | Santoro, ANNA MARIA; Zimbone, Stefania; Magri, Antonio; La Mendola, Diego; Grasso, Giulia | |
| Peptides derived from the histidine-proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties | 1-gen-2018 | Magrì, Antonio; Grasso, Giulia; Corti, Federico; Finetti, Federica; Greco, Valentina; Santoro, Anna Maria; Sciuto, Sebastiano; La Mendola, Diego; Morbidelli, Lucia; Rizzarelli, Enrico | |
| Peptides derived from the histidine-proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties | 1-gen-2018 | Antonio Magri; Giulia Grasso; Federico Corti; Federica Finetti; Valentina Greco; Anna Maria Santoro; Sebastiano Sciuto; Diego La Mendola; Lucia Morbidelli; Enrico Rizzarelli | |
| The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S | 1-gen-2018 | Sbardella, Diego; Tundo Grazia, R; Coletta, Andrea; Marcoux, Julien; Koufogeorgou Efthymia, Ioanna; Ciaccio, Chiara; Santoro Anna, M; Milardi, Danilo; Grasso, Giuseppe; Cozza, Paola; Bousquetdubouch, Mariepierre; Marini, Stefano; Coletta, Massimo | |
| Electrostatic Map of Proteasome ?-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding | 1-gen-2017 | Dato, Ad; Cunsolo, A; Persico, M; Santoro, Am; D'Urso, A; Milardi, D; Purrello, R; Stefanelli, M; Paolesse, R; Tundo, Gr; Sbardella, D; Fattorusso, C; Coletta, M | |
| The double faced role of copper in A beta homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration | 1-gen-2017 | Grasso, Giuseppe; Santoro, ANNA MARIA; Lanza, Valeria; Sbardella, Diego; Tundo Grazia, Raffaella; Ciaccio, Chiara; Marini, Stefano; Coletta, Massimo; Milardi, Danilo | |
| Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study | 1-gen-2016 | Anna Maria Santoro; Irene Monaco; Francesco Attanasio; Valeria Lanza;Giuseppe Pappalardo; Marianna Flora Tomasello; Alessandra Cunsolo; Enrico Rizzarelli;Ada De Luigi; Mario Salmona;Danilo Milardi |