D'URSI, PASQUALINA

D'URSI, PASQUALINA  

Istituto di Tecnologie Biomediche - ITB  

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Molecular Mechanisms Involved in the B Cell Growth and Clonogenic Activity of HIV-1 Matrix Protein p17 Variants 1-gen-2024 D'Ursi, Pasqualina; Rondina, Alessandro; Zani, Alberto; Uggeri, Matteo; Messali, Serena; Caruso, Arnaldo; Caccuri, Francesca
An innovative strategy to investigate microbial protein modifications in a reliable fast and sensitive way: A therapy oriented proof of concept based on UV-C irradiation of SARS-CoV-2 spike protein 1-gen-2023 Strizzi, Sergio; Bernardo, Letizia; D’Ursi, Pasqualina; Urbinati, Chiara; Bianco, Andrea; Limanaqi, Fiona; Manconi, Andrea; Milanesi, Maria; Macchi, Alberto; DI SILVESTRE, Dario; Cavalleri, Adalberto; Pareschi, Giovanni; Rusnati, Marco; Clerici, Mario; Mauri, Pierluigi; Biasin, Mara
Germline NUP98 Variants in Two Siblings with a Rothmund-Thomson-Like Spectrum: Protein Functional Changes Predicted by Molecular Modeling 1-gen-2023 Colombo, Elisa Adele; Valiante, Michele; Uggeri, Matteo; Orro, Alessandro; Majore, Silvia; Grammatico, Paola; Gentilini, Davide; Finelli, Palma; Gervasini, Cristina; D'Ursi, Pasqualina; Larizza, Lidia
Implementation of a drug discovery pipeline on the D4Science platform 1-gen-2023 Orro, A; D'Ursi, P; Fossa, P; Candela, L; Panichi, G
An Update on CFTR Drug Discovery: Opportunities and Challenges 1-gen-2022 D'Ursi, Pasqualina; Fossa, Paola
Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin 1-gen-2022 Rusnati, Marco; Paiardi, Giulia; Tobia, Chiara; Urbinati, Chiara; Lodola, Alessio; D'Ursi, Pasqualina; Corrado, Miriam; Castelli, Riccardo; Wade, Rebecca C.; Tognolini, Massimiliano; Chiodelli, Paola
Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host 1-gen-2022 Caccuri, F; Messali, S; Bortolotti, D; Di Silvestre, D; De Palma, A; Cattaneo, C; Bertelli, A; Zani, A; Milanesi, M; Giovanetti, M; Campisi, G; Gentili, V; Bugatti, A; Filippini, F; Scaltriti, E; Pongolini, S; Tucci, A; Fiorentini, S; D'Ursi, P; Ciccozzi, M; Mauri, P; Rizzo, R; Caruso, A
Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing 1-gen-2022 Fossa, Paola; Uggeri, Matteo; Orro, Alessandro; Urbinati, Chiara; Rondina, Alessandro; Milanesi, Maria; Pedemonte, Nicoletta; Pesce, Emanuela; Padoan, Rita; Ford, Robert C.; Meng, Xin; Rusnati, Marco; D'Ursi, Pasqualina
A Bittersweet Computational Journey among Glycosaminoglycans 1-gen-2021 Paiardi, Giulia; Milanesi, Maria; Wade, Rebecca C.; D???ursi, Pasqualina; Rusnati, Marco
Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin 1-gen-2021 Caccuri, F; D'Ursi, P; Uggeri, M; Bugatti, A; Mazzuca, P; Zani, A; Filippini, F; Salmona, M; Ribatti, D; Slevin, M; Orro, A; Lu, W; Lio, P; Gallo, Rc; Caruso, A
HIV-1 Tat and Heparan Sulfate Proteoglycans Orchestrate the Setup of in Cis and in Trans Cell-Surface Interactions Functional to Lymphocyte Trans-Endothelial Migration 1-gen-2021 Urbinati, Chiara; Milanesi, Maria; Lauro, Nicola; Bertelli, Cinzia; David, Guido; D'Ursi, Pasqualina; Rusnati, Marco; Chiodelli, Paola
In silico drug repositioning on F508del-CFTR: A proof-of-concept study on the AIFA library 1-gen-2021 Orro, A; Uggeri, M; Rusnati, M; Urbinati, C; Pedemonte, N; Pesce, E; Moscatelli, M; Padoan, R; Cichero, E; Fossa, P; D'Ursi, P
Role of Q675H Mutation in Improving SARS-CoV-2 Spike Interaction with the Furin Binding Pocket 1-gen-2021 Bertelli, Anna; D'Ursi, Pasqualina; Campisi, Giovanni; Messali, Serena; Milanesi, Maria; Giovanetti, Marta; Ciccozzi, Massimo; Caccuri, Francesca; Caruso, Arnaldo
B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation 1-gen-2020 Giagulli, C; Caccuri, F; Zorzan, S; Bugatti, A; Zani, A; Filippini, F; Manocha, E; D'Ursi, P; Orro, A; Dolcetti, R; Caruso, A
Recent Strategic Advances in CFTR Drug Discovery: An Overview 1-gen-2020 Rusnati, Marco; D'Ursi, Pasqualina; Pedemonte, Nicoletta; Urbinati, Chiara; Ford Robert, C; Cichero, Elena; Uggeri, Matteo; Orro, Alessandro; Fossa, Paola
Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy 1-gen-2019 Bella, Pamela; Farini, Andrea; Banfi, Stefania; Parolini, Daniele; Tonna, Noemi; Meregalli, Mirella; Belicchi, Marzia; Erratico, Silvia; D'Ursi, Pasqualina; Bianco, Fabio; Legato, Mariella; Ruocco, Chiara; Sitzia, Clementina; Sangiorgi, Simone; Villa, Chiara; D'Antona, Giuseppe; Milanesi, Luciano; Nisoli, Enzo; Mauri, Pierluigi; Torrente, Yvan
Exploitation of a novel biosensor based on the full-length human F508de1-CFTR with computational studies, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue 1-gen-2019 D'Ursi, P; Uggeri, M; Urbinati, C; Millo, E; Paiardi, G; Milanesi, L; Ford, R C; Clews, J; Meng, X; Bergese, P; Ridolfi, A; Pedemonte, N; Fossa, P; Orro, A; Rusnati, M
Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications 1-gen-2019 Bugatti A.; Paiardi G.; Urbinati C.; Chiodelli P.; Orro A.; Uggeri M.; Milanesi L.; Caruso A.; Caccuri F.; D'Ursi P.; Rusnati M.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders 1-gen-2018 Fontana L; Bedeschi MF; Maitz S; Cereda A; Faré C; Motta S; Seresini A; D'Ursi P; Orro A; Pecile V; Calvello M; Selicorni A; Lalatta F; Milani D; Sirchia SM; Miozzo M; Tabano S.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders 1-gen-2018 Fontana, L.; Bedeschi, M. F.; Maitz, S.; Cereda, A.; Fare, C.; Motta, S.; Seresini, A.; D'Ursi, P.; Orro, A.; Pecile, V.; Calvello, M.; Selicorni, A.; Lalatta, F.; Milani, D.; Sirchia, S. M.; Miozzo, M.; Tabano, S.