D'URSI, PASQUALINA
D'URSI, PASQUALINA
Istituto di Tecnologie Biomediche - ITB
Implementation of a drug discovery pipeline on the D4Science platform
2023 Orro, A; D'Ursi, P; Fossa, P; Candela, L; Panichi, G
Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin
2021 Caccuri, F; D'Ursi, P; Uggeri, M; Bugatti, A; Mazzuca, P; Zani, A; Filippini, F; Salmona, M; Ribatti, D; Slevin, M; Orro, A; Lu, W; Lio, P; Gallo, Rc; Caruso, A
In silico drug repositioning on F508del-CFTR: A proof-of-concept study on the AIFA library
2021 Orro, A; Uggeri, M; Rusnati, M; Urbinati, C; Pedemonte, N; Pesce, E; Moscatelli, M; Padoan, R; Cichero, E; Fossa, P; D'Ursi, P
B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation
2020 Giagulli, C; Caccuri, F; Zorzan, S; Bugatti, A; Zani, A; Filippini, F; Manocha, E; D'Ursi, P; Orro, A; Dolcetti, R; Caruso, A
Recent Strategic Advances in CFTR Drug Discovery: An Overview
2020 Rusnati, Marco; D'Ursi, Pasqualina; Pedemonte, Nicoletta; Urbinati, Chiara; Ford Robert, C; Cichero, Elena; Uggeri, Matteo; Orro, Alessandro; Fossa, Paola
Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy
2019 Bella, Pamela; Farini, Andrea; Banfi, Stefania; Parolini, Daniele; Tonna, Noemi; Meregalli, Mirella; Belicchi, Marzia; Erratico, Silvia; D'Ursi, Pasqualina; Bianco, Fabio; Legato, Mariella; Ruocco, Chiara; Sitzia, Clementina; Sangiorgi, Simone; Villa, Chiara; D'Antona, Giuseppe; Milanesi, Luciano; Nisoli, Enzo; Mauri, Pierluigi; Torrente, Yvan
Exploitation of a novel biosensor based on the full-length human F508de1-CFTR with computational studies, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue
2019 D'Ursi, P; Uggeri, M; Urbinati, C; Millo, E; Paiardi, G; Milanesi, L; Ford, R C; Clews, J; Meng, X; Bergese, P; Ridolfi, A; Pedemonte, N; Fossa, P; Orro, A; Rusnati, M
Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications
2019 Bugatti A.; Paiardi G.; Urbinati C.; Chiodelli P.; Orro A.; Uggeri M.; Milanesi L.; Caruso A.; Caccuri F.; D'Ursi P.; Rusnati M.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders
2018 Fontana, L.; Bedeschi, M. F.; Maitz, S.; Cereda, A.; Fare, C.; Motta, S.; Seresini, A.; D'Ursi, P.; Orro, A.; Pecile, V.; Calvello, M.; Selicorni, A.; Lalatta, F.; Milani, D.; Sirchia, S. M.; Miozzo, M.; Tabano, S.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders
2018 Fontana L; Bedeschi MF; Maitz S; Cereda A; Faré C; Motta S; Seresini A; D'Ursi P; Orro A; Pecile V; Calvello M; Selicorni A; Lalatta F; Milani D; Sirchia SM; Miozzo M; Tabano S.
Genome-based analysis for the identification of genes involved in o-xylene degradation in Rhodococcus opacus R7
2018 Di Canito, Alessandra; Zampolli, Jessica; Orro, Alessandro; D'Ursi, Pasqualina; Milanesi, Luciano; Sello, Guido; Steinbuechel, Alexander; Di Gennaro, Patrizia
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
2018 Rusnati, Marco; Sala, Davide; Orro, Alessandro; Bugatti, Antonella; Trombetti, GABRIELE ANTONIO; Cichero, Elena; Urbinati, Chiara; Di Somma, Margherita; Millo, Enrico; Galietta Luis, J V; Milanesi, Luciano; Fossa, Paola; D'Ursi, Pasqualina
A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17
2017 Giagulli, Cinzia; D'Ursi, Pasqualina; He, Wangxiao; Zorzan, Simone; Caccuri, Francesca; Varney, Kristen; Orro, Alessandro; Marsico, Stefania; Otjacques, Benoit; Laudanna, Carlo; Milanesi, Luciano; Dolcetti, Riccardo; Fiorentini, Simona; Lu, Wuyuan; Caruso, Arnaldo
Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy
2016 D'Avila, Francesca; Meregalli, Mirella; Lupoli, Sara; Barcella, Matteo; Orro, Alessandro; De Santis, Francesca; Sitzia, Clementina; Farini, Andrea; D'Ursi, Pasqualina; Erratico, Silvia; Cristofani, Riccardo; Milanesi, Luciano; Braga, Daniele; Cusi, Daniele; Poletti, Angelo; Barlassina, Cristina; Torrente, Yvan
Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics
2016 D'Ursi, Pasqualina; Guariento, Sara; Trombetti, GABRIELE ANTONIO; Orro, Alessandro; Cichero, Elena; Milanesi, Luciano; Fossa, Paola; Bruno, Olga
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment
2016 Brullo, Chiara; Ricciarelli, Roberta; Prickaerts, Jos; Arancio, Ottavio; Massa, Matteo; Rotolo, Chiara; Romussi, Alessia; Rebosio, Claudia; Marengo, Barbara; Pronzato, Maria Adelaide; van Hagen, Britt T J; van Goethem, Nick P.; D'Ursi, Pasqualina; Orro, Alessandro; Milanesi, Luciano; Guariento, Sara; Cichero, Elena; Fossa, Paola; Fedele, Ernesto; Fedele, Ernesto; Bruno, Olga
Phenotype microarray analysis may unravel genetic determinants of the stress response by Rhodococcus aetherivorans BCP1 and Rhodococcus opacus R7
2016 Cappelletti, Martina; Fedi, Stefani; Zampolli, Jessica; Di Canito, Alessandra; D'Ursi, Pasqualina; Orro, Alessandro; Viti, Carlo; Milanesi, Luciano; Zannoni, Davide; Di Gennaro, Patrizia
Genome and Phenotype Microarray Analyses of Rhodococcus sp BCP1 and Rhodococcus opacus R7: Genetic Determinants and Metabolic Abilities with Environmental Relevance
2015 Orro, Alessandro; Cappelletti, Martina; D'Ursi, Pasqualina; Milanesi, Luciano; Di Canito, Alessandra; Zampolli, Jessica; Collina, Elena; Decorosi, Francesca; Viti, Carlo; Fedi, Stefano; Presentato, Alessandro; Zannoni, Davide; Di Gennaro, Patrizia
Exhaustive molecular dynamics on GPU architectures unveil side chain flexibilities in PDE4D catalytic site and suggest new opportunities for designing selectve inhibitors.
2014 Guariento Sara; ; D'Ursi Pasqualina; ; Fossa Paola; .
Genome Sequence of Rhodococcus opacus Strain R7, a Biodegrader of Mono- and Polycyclic Aromatic Hydrocarbons.
2014 Di Gennaro, P; Zampolli, J; Presti, I; Cappelletti, M; D'Ursi, P; Orro, A; Mezzelani, A; Milanesi, L
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Implementation of a drug discovery pipeline on the D4Science platform | 1-gen-2023 | Orro, A; D'Ursi, P; Fossa, P; Candela, L; Panichi, G | |
| Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin | 1-gen-2021 | Caccuri, F; D'Ursi, P; Uggeri, M; Bugatti, A; Mazzuca, P; Zani, A; Filippini, F; Salmona, M; Ribatti, D; Slevin, M; Orro, A; Lu, W; Lio, P; Gallo, Rc; Caruso, A | |
| In silico drug repositioning on F508del-CFTR: A proof-of-concept study on the AIFA library | 1-gen-2021 | Orro, A; Uggeri, M; Rusnati, M; Urbinati, C; Pedemonte, N; Pesce, E; Moscatelli, M; Padoan, R; Cichero, E; Fossa, P; D'Ursi, P | |
| B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation | 1-gen-2020 | Giagulli, C; Caccuri, F; Zorzan, S; Bugatti, A; Zani, A; Filippini, F; Manocha, E; D'Ursi, P; Orro, A; Dolcetti, R; Caruso, A | |
| Recent Strategic Advances in CFTR Drug Discovery: An Overview | 1-gen-2020 | Rusnati, Marco; D'Ursi, Pasqualina; Pedemonte, Nicoletta; Urbinati, Chiara; Ford Robert, C; Cichero, Elena; Uggeri, Matteo; Orro, Alessandro; Fossa, Paola | |
| Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy | 1-gen-2019 | Bella, Pamela; Farini, Andrea; Banfi, Stefania; Parolini, Daniele; Tonna, Noemi; Meregalli, Mirella; Belicchi, Marzia; Erratico, Silvia; D'Ursi, Pasqualina; Bianco, Fabio; Legato, Mariella; Ruocco, Chiara; Sitzia, Clementina; Sangiorgi, Simone; Villa, Chiara; D'Antona, Giuseppe; Milanesi, Luciano; Nisoli, Enzo; Mauri, Pierluigi; Torrente, Yvan | |
| Exploitation of a novel biosensor based on the full-length human F508de1-CFTR with computational studies, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue | 1-gen-2019 | D'Ursi, P; Uggeri, M; Urbinati, C; Millo, E; Paiardi, G; Milanesi, L; Ford, R C; Clews, J; Meng, X; Bergese, P; Ridolfi, A; Pedemonte, N; Fossa, P; Orro, A; Rusnati, M | |
| Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications | 1-gen-2019 | Bugatti A.; Paiardi G.; Urbinati C.; Chiodelli P.; Orro A.; Uggeri M.; Milanesi L.; Caruso A.; Caccuri F.; D'Ursi P.; Rusnati M. | |
| Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders | 1-gen-2018 | Fontana, L.; Bedeschi, M. F.; Maitz, S.; Cereda, A.; Fare, C.; Motta, S.; Seresini, A.; D'Ursi, P.; Orro, A.; Pecile, V.; Calvello, M.; Selicorni, A.; Lalatta, F.; Milani, D.; Sirchia, S. M.; Miozzo, M.; Tabano, S. | |
| Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders | 1-gen-2018 | Fontana L; Bedeschi MF; Maitz S; Cereda A; Faré C; Motta S; Seresini A; D'Ursi P; Orro A; Pecile V; Calvello M; Selicorni A; Lalatta F; Milani D; Sirchia SM; Miozzo M; Tabano S. | |
| Genome-based analysis for the identification of genes involved in o-xylene degradation in Rhodococcus opacus R7 | 1-gen-2018 | Di Canito, Alessandra; Zampolli, Jessica; Orro, Alessandro; D'Ursi, Pasqualina; Milanesi, Luciano; Sello, Guido; Steinbuechel, Alexander; Di Gennaro, Patrizia | |
| Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance. | 1-gen-2018 | Rusnati, Marco; Sala, Davide; Orro, Alessandro; Bugatti, Antonella; Trombetti, GABRIELE ANTONIO; Cichero, Elena; Urbinati, Chiara; Di Somma, Margherita; Millo, Enrico; Galietta Luis, J V; Milanesi, Luciano; Fossa, Paola; D'Ursi, Pasqualina | |
| A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17 | 1-gen-2017 | Giagulli, Cinzia; D'Ursi, Pasqualina; He, Wangxiao; Zorzan, Simone; Caccuri, Francesca; Varney, Kristen; Orro, Alessandro; Marsico, Stefania; Otjacques, Benoit; Laudanna, Carlo; Milanesi, Luciano; Dolcetti, Riccardo; Fiorentini, Simona; Lu, Wuyuan; Caruso, Arnaldo | |
| Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy | 1-gen-2016 | D'Avila, Francesca; Meregalli, Mirella; Lupoli, Sara; Barcella, Matteo; Orro, Alessandro; De Santis, Francesca; Sitzia, Clementina; Farini, Andrea; D'Ursi, Pasqualina; Erratico, Silvia; Cristofani, Riccardo; Milanesi, Luciano; Braga, Daniele; Cusi, Daniele; Poletti, Angelo; Barlassina, Cristina; Torrente, Yvan | |
| Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics | 1-gen-2016 | D'Ursi, Pasqualina; Guariento, Sara; Trombetti, GABRIELE ANTONIO; Orro, Alessandro; Cichero, Elena; Milanesi, Luciano; Fossa, Paola; Bruno, Olga | |
| New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment | 1-gen-2016 | Brullo, Chiara; Ricciarelli, Roberta; Prickaerts, Jos; Arancio, Ottavio; Massa, Matteo; Rotolo, Chiara; Romussi, Alessia; Rebosio, Claudia; Marengo, Barbara; Pronzato, Maria Adelaide; van Hagen, Britt T J; van Goethem, Nick P.; D'Ursi, Pasqualina; Orro, Alessandro; Milanesi, Luciano; Guariento, Sara; Cichero, Elena; Fossa, Paola; Fedele, Ernesto; Fedele, Ernesto; Bruno, Olga | |
| Phenotype microarray analysis may unravel genetic determinants of the stress response by Rhodococcus aetherivorans BCP1 and Rhodococcus opacus R7 | 1-gen-2016 | Cappelletti, Martina; Fedi, Stefani; Zampolli, Jessica; Di Canito, Alessandra; D'Ursi, Pasqualina; Orro, Alessandro; Viti, Carlo; Milanesi, Luciano; Zannoni, Davide; Di Gennaro, Patrizia | |
| Genome and Phenotype Microarray Analyses of Rhodococcus sp BCP1 and Rhodococcus opacus R7: Genetic Determinants and Metabolic Abilities with Environmental Relevance | 1-gen-2015 | Orro, Alessandro; Cappelletti, Martina; D'Ursi, Pasqualina; Milanesi, Luciano; Di Canito, Alessandra; Zampolli, Jessica; Collina, Elena; Decorosi, Francesca; Viti, Carlo; Fedi, Stefano; Presentato, Alessandro; Zannoni, Davide; Di Gennaro, Patrizia | |
| Exhaustive molecular dynamics on GPU architectures unveil side chain flexibilities in PDE4D catalytic site and suggest new opportunities for designing selectve inhibitors. | 1-gen-2014 | Guariento Sara; ; D'Ursi Pasqualina; ; Fossa Paola; . | |
| Genome Sequence of Rhodococcus opacus Strain R7, a Biodegrader of Mono- and Polycyclic Aromatic Hydrocarbons. | 1-gen-2014 | Di Gennaro, P; Zampolli, J; Presti, I; Cappelletti, M; D'Ursi, P; Orro, A; Mezzelani, A; Milanesi, L |