DI NATALE, GIUSEPPE
DI NATALE, GIUSEPPE
Istituto di Cristallografia - IC
A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction
2024 Tosto, Rita; Zimbone, Stefania; Di Natale, Giuseppe; Giuffrida, Maria Laura; Campagna, Tiziana; Pappalardo, Giuseppe; Sabatino, Giuseppina
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment
2023 Zimbone, S.; Giuffrida, M. L.; Sabatino, G.; Di Natale, G.; Tosto, R.; Consoli, G. M. L.; Milardi, D.; Pappalardo, G.; Sciacca, M. F. M.
The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment
2023 Stefania Zimbone; Maria Laura Giuffrida; Giuseppina Sabatino; Giuseppe Di Natale; Rita Tosto; Grazia M. L. Consoli; Danilo Milardi; Giuseppe Pappalardo; Michele F.M. Sciacca
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease?
2022 DI NATALE, Giuseppe; Sabatino, Giuseppina; Sciacca, MICHELE FRANCESCO MARIA; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe
KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing
2022 Mazzaglia, Antonino; DI NATALE, Giuseppe; Tosto, Rita; Scala, Angela; Sortino, Giuseppe; Piperno, Anna; Casaletto, MARIA PIA; Riminucci, Alberto; Giuffrida, MARIA LAURA; Mineo Placido, G; Villari, Valentina; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe
Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study
2021 Balogh, Bd; Szakacs, B; Di Natale, G; Tabbi, G; Pappalardo, G; Sovago, I; Varnagy, K
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro
2021 Consoli, GRAZIA MARIA LETIZIA; Tosto, R.; Baglieri, A.; Petralia, S.; Campagna, T.; DI NATALE, Giuseppe; Zimbone, S.; Giuffrida, M. L.; Pappalardo, Giuseppe.
Tau/A? chimera peptides: A Thioflavin-T and MALDI-TOF study of A? amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles
2021 Sciacca, Mfm; Di Natale, G; Milardi, D; Pappalardo, G
Interaction between hemin and prion peptides: Binding, oxidative reactivity and aggregation
2020 Dell'acqua S.; Massardi E.; Monzani E.; Di Natale G.; Rizzarelli E.; Casella L.
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence
2020 Sciacca, Michele Francesco Maria; Di Natale, Giuseppe; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe
Zinc Interactions with a Soluble Mutated Rat Amylin to Mimic Whole Human Amylin: An Experimental and Simulation Approach to Understand Stoichiometry, Speciation and Coordination of the Metal Complexes
2020 Magri A.; Tabbi G.; Di Natale G.; La Mendola D.; Pietropaolo A.; Zoroddu M.A.; Peana M.; Rizzarelli E.
Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study
2019 Lukacs M.; Szunyog G.; Grenacs A.; Lihi N.; Kallay C.; Di Natale G.; Campagna T.; Lanza V.; Tabbi G.; Pappalardo G.; Sovago I.; Varnagy K.
Copper-assisted interaction between amyloid-? and prion: Ternary metal complexes with A? N-terminus and octarepeat
2018 Magri, A; Di Natale, G; Rizzarelli, E
Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose-conjugated beta sheet breaker peptides
2018 Di Natale, G.; Zimbone, S.; Bellia, F.; Tomasello, M. F.; Giuffrida, M. L.; Pappalardo, G.; Rizzarelli, E.
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases
2018 Lanza, Valeria; Milardi, Danilo; DI NATALE, Giuseppe; Pappalardo, Giuseppe
Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-? aggregation
2018 Di Natale G.; Bellia F.; Sciacca M.F.M.; Campagna T.; Pappalardo G.
A Metalloporphyrin-Peptide Conjugate as an Effective Inhibitor of Amyloid-beta Peptide Fibrillation and Cytotoxicity
2017 Villari, Valentina; Villari, Valentina; Tosto, Rita; Tosto, Rita; Natale, Di; Pappalardo, Giuseppe; Sinopoli, ; Alessandro, ; Tomasello, MARIANNA FLORA; Marianna, F; Lazzaro, ; Serena, ; Micali, NORBERTO LIBORIO; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe; Pappalardo, Giuseppe
New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway
2017 Tomasello, Marianna F.; Nardon, Chiara; Lanza, Valeria; Di Natale, Giuseppe; Pettenuzzo, Nicolo; Salmaso, Stefano; Milardi, Danilo; Caliceti, Paolo; Pappalardo, Giuseppe; Fregona, Dolores
Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress
2017 Dell'Acqua S.; Bacchella C.; Monzani E.; Nicolis S.; Di Natale G.; Rizzarelli E.; Casella L.
Copper(II) coordination properties of the A?(1-16)2 peptidomimetic: an experimental evidence of intermolecular macrochelate complex species in the A? dimer
2016 Giuseppe Di Natale; Alessandro Sinopoli; Agnes Grenacs; Daniele Sanna; Imre Sovago ; Giuseppe Pappalardo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction | 1-gen-2024 | Tosto, Rita; Zimbone, Stefania; Di Natale, Giuseppe; Giuffrida, Maria Laura; Campagna, Tiziana; Pappalardo, Giuseppe; Sabatino, Giuseppina | |
| Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment | 1-gen-2023 | Zimbone, S.; Giuffrida, M. L.; Sabatino, G.; Di Natale, G.; Tosto, R.; Consoli, G. M. L.; Milardi, D.; Pappalardo, G.; Sciacca, M. F. M. | |
| The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment | 1-gen-2023 | Stefania Zimbone; Maria Laura Giuffrida; Giuseppina Sabatino; Giuseppe Di Natale; Rita Tosto; Grazia M. L. Consoli; Danilo Milardi; Giuseppe Pappalardo; Michele F.M. Sciacca | |
| A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? | 1-gen-2022 | DI NATALE, Giuseppe; Sabatino, Giuseppina; Sciacca, MICHELE FRANCESCO MARIA; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe | |
| KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing | 1-gen-2022 | Mazzaglia, Antonino; DI NATALE, Giuseppe; Tosto, Rita; Scala, Angela; Sortino, Giuseppe; Piperno, Anna; Casaletto, MARIA PIA; Riminucci, Alberto; Giuffrida, MARIA LAURA; Mineo Placido, G; Villari, Valentina; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe | |
| Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study | 1-gen-2021 | Balogh, Bd; Szakacs, B; Di Natale, G; Tabbi, G; Pappalardo, G; Sovago, I; Varnagy, K | |
| Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro | 1-gen-2021 | Consoli, GRAZIA MARIA LETIZIA; Tosto, R.; Baglieri, A.; Petralia, S.; Campagna, T.; DI NATALE, Giuseppe; Zimbone, S.; Giuffrida, M. L.; Pappalardo, Giuseppe. | |
| Tau/A? chimera peptides: A Thioflavin-T and MALDI-TOF study of A? amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles | 1-gen-2021 | Sciacca, Mfm; Di Natale, G; Milardi, D; Pappalardo, G | |
| Interaction between hemin and prion peptides: Binding, oxidative reactivity and aggregation | 1-gen-2020 | Dell'acqua S.; Massardi E.; Monzani E.; Di Natale G.; Rizzarelli E.; Casella L. | |
| Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence | 1-gen-2020 | Sciacca, Michele Francesco Maria; Di Natale, Giuseppe; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe | |
| Zinc Interactions with a Soluble Mutated Rat Amylin to Mimic Whole Human Amylin: An Experimental and Simulation Approach to Understand Stoichiometry, Speciation and Coordination of the Metal Complexes | 1-gen-2020 | Magri A.; Tabbi G.; Di Natale G.; La Mendola D.; Pietropaolo A.; Zoroddu M.A.; Peana M.; Rizzarelli E. | |
| Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study | 1-gen-2019 | Lukacs M.; Szunyog G.; Grenacs A.; Lihi N.; Kallay C.; Di Natale G.; Campagna T.; Lanza V.; Tabbi G.; Pappalardo G.; Sovago I.; Varnagy K. | |
| Copper-assisted interaction between amyloid-? and prion: Ternary metal complexes with A? N-terminus and octarepeat | 1-gen-2018 | Magri, A; Di Natale, G; Rizzarelli, E | |
| Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose-conjugated beta sheet breaker peptides | 1-gen-2018 | Di Natale, G.; Zimbone, S.; Bellia, F.; Tomasello, M. F.; Giuffrida, M. L.; Pappalardo, G.; Rizzarelli, E. | |
| Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases | 1-gen-2018 | Lanza, Valeria; Milardi, Danilo; DI NATALE, Giuseppe; Pappalardo, Giuseppe | |
| Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-? aggregation | 1-gen-2018 | Di Natale G.; Bellia F.; Sciacca M.F.M.; Campagna T.; Pappalardo G. | |
| A Metalloporphyrin-Peptide Conjugate as an Effective Inhibitor of Amyloid-beta Peptide Fibrillation and Cytotoxicity | 1-gen-2017 | Villari, Valentina; Villari, Valentina; Tosto, Rita; Tosto, Rita; Natale, Di; Pappalardo, Giuseppe; Sinopoli, ; Alessandro, ; Tomasello, MARIANNA FLORA; Marianna, F; Lazzaro, ; Serena, ; Micali, NORBERTO LIBORIO; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe; Pappalardo, Giuseppe | |
| New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway | 1-gen-2017 | Tomasello, Marianna F.; Nardon, Chiara; Lanza, Valeria; Di Natale, Giuseppe; Pettenuzzo, Nicolo; Salmaso, Stefano; Milardi, Danilo; Caliceti, Paolo; Pappalardo, Giuseppe; Fregona, Dolores | |
| Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress | 1-gen-2017 | Dell'Acqua S.; Bacchella C.; Monzani E.; Nicolis S.; Di Natale G.; Rizzarelli E.; Casella L. | |
| Copper(II) coordination properties of the A?(1-16)2 peptidomimetic: an experimental evidence of intermolecular macrochelate complex species in the A? dimer | 1-gen-2016 | Giuseppe Di Natale; Alessandro Sinopoli; Agnes Grenacs; Daniele Sanna; Imre Sovago ; Giuseppe Pappalardo |