PESARESI, ALESSANDRO
PESARESI, ALESSANDRO
Istituto di Cristallografia - IC - Sede Secondaria Trieste
Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged‐like inactive complex susceptible to reactivation by a combination of nucleophiles
2024 Stojan, Jure; Pesaresi, Alessandro; Meden, Anže; Lamba, Doriano
Mixed and non-competitive enzyme inhibition: underlying mechanisms andmechanistic irrelevance of the formal two-site model
2023 Pesaresi, Alessandro
Nonallosteric activation of posttranslational modification enzymes by active site-directed inhibitors
2023 Pesaresi, Alessandro
Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives
2022 Pesaresi, A; Lamba, D; Vezenkov, L; Tsekova, D; Lozanov, V
Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine
2022 Lamba, Doriano; Pesaresi, Alessandro
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 Chalupova K.; Korabecny J.; Bartolini M.; Monti B.; Lamba D.; Caliandro R.; Pesaresi A.; Brazzolotto X.; Gastellier A.J.; Nachon F.; Pejchal J.; Jarosova M.; Hepnarova V.; Jun D.; Hrabinova M.; Dolezal R.; Zdarova Karasova J.; Mzik M.; Kristofikova Z.; Misik J.; Muckova L.; Jost P.; Soukup O.; Benkova M.; Setnicka V.; Habartova L.; Chvojkova M.; Kleteckova L.; Vales K.; Mezeiova E.; Uliassi E.; Valis M.; Nepovimova E.; Bolognesi M.L.; Kuca K.
"Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid Analogues"
2018 Caliandro R.; Pesaresi A.; Cariati L. Procopio A.; Oliverio M.; Lamba D.
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease:Design, Synthesis, Biological Evaluation and X-ray Crystallography
2016 Zha, Xiaoming; Lamba, Doriano; Zhanga, Lili; A, Yinghan Lou; D, ; Xua, Changxu; Dikanga, ; Chen, Li; Xu, Yungen; Zhang, Luyong; De Simone, Angela; B, Sarah Samez; F, ; Pesaresi, Alessandro; Stojan, Jure; G Lopez, Manuela; Egea, Javier; Vincenzaandrisano, ; Bartolini, Manuela
Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects
2014 Nepovímová, Eugenie; Uliassi, Elisa; Korábecný, Jan; PeñaAltamira, Luis Emiliano; Samez, Sarah; Pesaresi, Alessandro; Garcia, Gregory E.; Bartolini, Manuela; Andrisano, Vincenza; Bergamini, Christian; Fato, Romana; Lamba, Doriano; Roberti, Marinella; Kuca, Kamil; Monti, Barbara; Bolognesi, M. L.
Evaluation and computational characterization of the facilitated transport of Glc carbon C-1 oxime reactivators across a blood brain barrier model
2013 Bhonsle, ; J, B; Causey, R; Oyler, ; B, L; Bartolucci, C; Lamba, D; Pesaresi, A; Bhamare, ; N, K; Soojhawon, I; Garcia, ; G, E
Role of metal ions on the activity of Mycobacterium tuberculosis pyrazinamidase
2012 Sheen P; Ferrer P; Gilman; R H; Christiansen G; MorenoRomán P; Gutiérrez; A H; Sotelo J; Evangelista W; Fuentes P; Rueda D; Flores M; Olivera P; Solis J; Pesaresi A; Lamba D; Zimic; M
In vitro characterization of Arabidopsis CP12 isoforms reveals common biochemical and molecular properties.
2010 Marri L; Pesaresi A; Valerio C; Lamba D; Pupillo P; Trost P; Sparla F.
Insights into the fatty acid chain length specificity of the carboxylesterase PA3859 from Pseudomonas aeruginosa: A combined structural, biochemical and computational study.
2010 Pesaresi A.; Lamba D.
Crystallization, X-ray diffraction analysis and phasing of carboxylesterase PA3859 from Pseudomonas aeruginosa.
2005 Pesaresi, A; Lamba, D
Isolation, characterization, and heterologous expression of a carboxylesterase of Pseudomonas aeruginosa PAO1.
2005 Pesaresi, A; Devescovi, G; Lamba, D; Venturi, V; Degrassi, G