DE FALCO, VALENTINA
DE FALCO, VALENTINA
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure
2004 Orgiana, Giuseppina; Pinna Giovanni, Battista; Camedda, A; DE FALCO, Valentina; Santoro Massimo, Mattia; Melillo Rosa, Marina; Elisei, Rossella; Romei, Cristina; Lai, S; Carcassi, Carlo; Mariotti, Stefano
A novel pathway of cell growth regulation mediated by a PLA2alpha-derived phosphoinositide metabolite
2006 Mariggiò, S; Sebastià, J; Filippi, Bm; Iurisci, C; Volonté, C; Amadio, S; De Falco, V; Santoro, M; Corda, D
A novel pathway of cell growth regulation mediated by a PLA2{alpha}-derived phosphoinositide metabolite.
2006 Mariggio, S; Sebastia, J; Filippi, Bm; Iurisci, C; Volontè, C; Amadio, S; De Falco, V; Santoro, M; Corda, D
Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma.
2006 Moretti, S; Macchiarulo, A; De Falco, V; Avenia, N; Barbi, F; Carta, C; Cavaliere, A; Melillo, Rm; Passeri, L; Santeusanio, F; Tartaglia, M; Santoro, M; Puxeddu, E
Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer
2007 De Falco, V; Guarino, V; Avilla, E; Castellone, ; M, D; Salerno, P; Salvatore, G; Faviana, P; Basolo, F; Santoro, M; Melillo, ; R, M
BRAF is a therapeutic target in aggressive thyroid carcinoma.
2006 Salvatore G; De Falco V; Salerno P; Nappi TC; Pepe S; Troncone G; Carlomagno F; Melillo RM; Wilhelm SM; Santoro M.
Calcium/calmodulin-dependent protein kinase II and its endogenous inhibitor ? in medullary thyroid cancer.
2014 Russo, E; Salzano, M; De Falco, V; Mian, C; Barollo, S; Secondo, A; Bifulco, M; Vitale, M
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
2023 Anand, U.; Dey, A.; Chandel, A. K. S.; Sanyal, R.; Mishra, A.; Pandey, D. K.; De Falco, V.; Upadhyay, A.; Kandimalla, R.; Chaudhary, A.; Dhanjal, J. K.; Dewanjee, S.; Vallamkondu, J.; Perez de la Lastra, J. M.
CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells.
2012 De Falco V; Tamburrino A; Ventre S; Castellone MD; Malek M; Manié SN; Santoro M.
Cytosolic phospholipase A2? regulates cell growth in RET/PTC-transformed thyroid cells
2007 Mariggiò S; Filippi BM; Iurisci C; Dragani LK; De Falco V; Santoro M; Corda D.
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells
2010 Salerno, Paolo; De Falco, Valentina; Tamburrino, Anna; Nappi, Tito Claudio; Vecchio, Giancarlo; Schweppe, Rebecca E.; Bollag, Gideon E.; Santoro, Massimo Mattia; Salvátore, Giuliana
Effects of combined administration of rapamycin, tolvaptan and AEZ-131 on progression of polycystic disease in PCK rats.
2014 Sabbatini, M; Russo, L; Cappellaio, F; Troncone, G; Bellevicine, C; De Falco, V; Buonocore, P; Riccio, E; Bisesti, V; Federico, S; Pisani, A
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology
2015 Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu
Functional characterization of the novel T599I-VKSRdel BRAF mutation in a follicular variant papillary thyroid carcinoma.
2008 De Falco, V; Giannini, R; Tamburrino, A; Ugolini, C; Lupi, C; Puxeddu, E; Santoro, M; Basolo, F
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas
2004 Castellone, Maria Domenica; Guarino, Valentina; De Falco, Valentina; Carlomagno, Francesca; Basolo, Fulvio; Faviana, Pinuccia; Kruhøffer, Mogens; Örntoft, Torben Falck; Russell, John P.; Rothstein, Jay L.; Fusco, Alfredo; Santoro, Massimo Mattia; Melillo, Rosa Marina
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif
2009 Moretti, Sonia; DE FALCO, Valentina; Tamburrino, Anna; Barbi, Flavia; Tavano, Maria; Avenia, N; Santeusanio, Fausto; Santoro Massimo, Mattia; Macchiarulo, Antonio; Puxeddu, Efisio
Mitochondrial Localization and Regulation of BRAF(V600E) in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAF(V600E)
2011 Lee, Min Hee; Lee, Seong Eun; Kim, Dong Wook; Ryu, Min Jeong; Kim, Sung Jin; Kim, Sung Joong; Kim, Yong Kyoung; Park, Ji Hoon; Kweon, Gi Ryang; Kim, Jin Man; Lee, Jung Uee; De Falco, Valentina; Jo, Young Suk; Shong, Minho
Molecular genetics of medullary thyroid carcinoma: The quest for novel therapeutic targets
2009 Cerrato, A; De Falco, V; Santoro, ; M,
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: Identification of gain-of-function mutations in the RET proto-oncogene
2018 Mendes Oliveira, D; Grillone, K; Mignogna, C; De Falco, V; Laudanna, C; Biamonte, F; Locane, R; Corcione, F; Fabozzi, M; Sacco, R; Viglietto, G; Malanga, D; Rizzuto, A
Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness
2005 Guarino, V; Faviana, P; Salvatore, G; Castellone, ; M, D; Cirafici, ; A, M; De Falco, V; Celetti, A; Giannini, R; Basolo, F; Melillo, ; R, M; Santoro, ; M,
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure | 1-gen-2004 | Orgiana, Giuseppina; Pinna Giovanni, Battista; Camedda, A; DE FALCO, Valentina; Santoro Massimo, Mattia; Melillo Rosa, Marina; Elisei, Rossella; Romei, Cristina; Lai, S; Carcassi, Carlo; Mariotti, Stefano | |
A novel pathway of cell growth regulation mediated by a PLA2alpha-derived phosphoinositide metabolite | 1-gen-2006 | Mariggiò, S; Sebastià, J; Filippi, Bm; Iurisci, C; Volonté, C; Amadio, S; De Falco, V; Santoro, M; Corda, D | |
A novel pathway of cell growth regulation mediated by a PLA2{alpha}-derived phosphoinositide metabolite. | 1-gen-2006 | Mariggio, S; Sebastia, J; Filippi, Bm; Iurisci, C; Volontè, C; Amadio, S; De Falco, V; Santoro, M; Corda, D | |
Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma. | 1-gen-2006 | Moretti, S; Macchiarulo, A; De Falco, V; Avenia, N; Barbi, F; Carta, C; Cavaliere, A; Melillo, Rm; Passeri, L; Santeusanio, F; Tartaglia, M; Santoro, M; Puxeddu, E | |
Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer | 1-gen-2007 | De Falco, V; Guarino, V; Avilla, E; Castellone, ; M, D; Salerno, P; Salvatore, G; Faviana, P; Basolo, F; Santoro, M; Melillo, ; R, M | |
BRAF is a therapeutic target in aggressive thyroid carcinoma. | 1-gen-2006 | Salvatore G; De Falco V; Salerno P; Nappi TC; Pepe S; Troncone G; Carlomagno F; Melillo RM; Wilhelm SM; Santoro M. | |
Calcium/calmodulin-dependent protein kinase II and its endogenous inhibitor ? in medullary thyroid cancer. | 1-gen-2014 | Russo, E; Salzano, M; De Falco, V; Mian, C; Barollo, S; Secondo, A; Bifulco, M; Vitale, M | |
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics | 1-gen-2023 | Anand, U.; Dey, A.; Chandel, A. K. S.; Sanyal, R.; Mishra, A.; Pandey, D. K.; De Falco, V.; Upadhyay, A.; Kandimalla, R.; Chaudhary, A.; Dhanjal, J. K.; Dewanjee, S.; Vallamkondu, J.; Perez de la Lastra, J. M. | |
CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells. | 1-gen-2012 | De Falco V; Tamburrino A; Ventre S; Castellone MD; Malek M; Manié SN; Santoro M. | |
Cytosolic phospholipase A2? regulates cell growth in RET/PTC-transformed thyroid cells | 1-gen-2007 | Mariggiò S; Filippi BM; Iurisci C; Dragani LK; De Falco V; Santoro M; Corda D. | |
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells | 1-gen-2010 | Salerno, Paolo; De Falco, Valentina; Tamburrino, Anna; Nappi, Tito Claudio; Vecchio, Giancarlo; Schweppe, Rebecca E.; Bollag, Gideon E.; Santoro, Massimo Mattia; Salvátore, Giuliana | |
Effects of combined administration of rapamycin, tolvaptan and AEZ-131 on progression of polycystic disease in PCK rats. | 1-gen-2014 | Sabbatini, M; Russo, L; Cappellaio, F; Troncone, G; Bellevicine, C; De Falco, V; Buonocore, P; Riccio, E; Bisesti, V; Federico, S; Pisani, A | |
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology | 1-gen-2015 | Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu | |
Functional characterization of the novel T599I-VKSRdel BRAF mutation in a follicular variant papillary thyroid carcinoma. | 1-gen-2008 | De Falco, V; Giannini, R; Tamburrino, A; Ugolini, C; Lupi, C; Puxeddu, E; Santoro, M; Basolo, F | |
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas | 1-gen-2004 | Castellone, Maria Domenica; Guarino, Valentina; De Falco, Valentina; Carlomagno, Francesca; Basolo, Fulvio; Faviana, Pinuccia; Kruhøffer, Mogens; Örntoft, Torben Falck; Russell, John P.; Rothstein, Jay L.; Fusco, Alfredo; Santoro, Massimo Mattia; Melillo, Rosa Marina | |
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif | 1-gen-2009 | Moretti, Sonia; DE FALCO, Valentina; Tamburrino, Anna; Barbi, Flavia; Tavano, Maria; Avenia, N; Santeusanio, Fausto; Santoro Massimo, Mattia; Macchiarulo, Antonio; Puxeddu, Efisio | |
Mitochondrial Localization and Regulation of BRAF(V600E) in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAF(V600E) | 1-gen-2011 | Lee, Min Hee; Lee, Seong Eun; Kim, Dong Wook; Ryu, Min Jeong; Kim, Sung Jin; Kim, Sung Joong; Kim, Yong Kyoung; Park, Ji Hoon; Kweon, Gi Ryang; Kim, Jin Man; Lee, Jung Uee; De Falco, Valentina; Jo, Young Suk; Shong, Minho | |
Molecular genetics of medullary thyroid carcinoma: The quest for novel therapeutic targets | 1-gen-2009 | Cerrato, A; De Falco, V; Santoro, ; M, | |
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: Identification of gain-of-function mutations in the RET proto-oncogene | 1-gen-2018 | Mendes Oliveira, D; Grillone, K; Mignogna, C; De Falco, V; Laudanna, C; Biamonte, F; Locane, R; Corcione, F; Fabozzi, M; Sacco, R; Viglietto, G; Malanga, D; Rizzuto, A | |
Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness | 1-gen-2005 | Guarino, V; Faviana, P; Salvatore, G; Castellone, ; M, D; Cirafici, ; A, M; De Falco, V; Celetti, A; Giannini, R; Basolo, F; Melillo, ; R, M; Santoro, ; M, |