DE FALCO, VALENTINA
DE FALCO, VALENTINA
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
2023 Anand, U.; Dey, A.; Chandel, A. K. S.; Sanyal, R.; Mishra, A.; Pandey, D. K.; De Falco, V.; Upadhyay, A.; Kandimalla, R.; Chaudhary, A.; Dhanjal, J. K.; Dewanjee, S.; Vallamkondu, J.; Perez de la Lastra, J. M.
p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors
2022 Maietta, I.; Del Peschio, F.; Buonocore, P.; Viscusi, E.; Laudati, S.; Iannaci, G.; Minopoli, M.; Motti, M. L.; De Falco, V.
Targeted Cancer Therapy and Mechanisms of Resistance
2022 DE FALCO, Valentina
The Role of Nutrients in Prevention, Treatment and Post-Coronavirus Disease-2019 (COVID-19)
2022 Motti, M. L.; Tafuri, D.; Donini, L.; Masucci, M. T.; De Falco, V.; Mazzeo, F.
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: Identification of gain-of-function mutations in the RET proto-oncogene
2018 Mendes Oliveira, D; Grillone, K; Mignogna, C; De Falco, V; Laudanna, C; Biamonte, F; Locane, R; Corcione, F; Fabozzi, M; Sacco, R; Viglietto, G; Malanga, D; Rizzuto, A
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer
2017 De Falco V.; Carlomagno F.; Li H.Y.; Santoro M.
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology
2015 Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu
Calcium/calmodulin-dependent protein kinase II and its endogenous inhibitor ? in medullary thyroid cancer.
2014 Russo, E; Salzano, M; De Falco, V; Mian, C; Barollo, S; Secondo, A; Bifulco, M; Vitale, M
Effects of combined administration of rapamycin, tolvaptan and AEZ-131 on progression of polycystic disease in PCK rats.
2014 Sabbatini, M; Russo, L; Cappellaio, F; Troncone, G; Bellevicine, C; De Falco, V; Buonocore, P; Riccio, E; Bisesti, V; Federico, S; Pisani, A
Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer.
2013 De Falco, V; Buonocore, P; Muthu, M; Torregrossa, L; Basolo, F; Billaud, M; Gozgit, Jm; Carlomagno, F; Santoro, M
CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells.
2012 De Falco V; Tamburrino A; Ventre S; Castellone MD; Malek M; Manié SN; Santoro M.
XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt.
2012 Shiozaki, A; Shentu, G; Bai, X; Iitaka, D; De Falco, V; Santoro, M; Keshavjee, S; Liu, M
Mitochondrial Localization and Regulation of BRAF(V600E) in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAF(V600E)
2011 Lee, Min Hee; Lee, Seong Eun; Kim, Dong Wook; Ryu, Min Jeong; Kim, Sung Jin; Kim, Sung Joong; Kim, Yong Kyoung; Park, Ji Hoon; Kweon, Gi Ryang; Kim, Jin Man; Lee, Jung Uee; De Falco, Valentina; Jo, Young Suk; Shong, Minho
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells
2011 Vitagliano, Donata; DE FALCO, Valentina; Tamburrino, Anna; Coluzzi, Sabrina; Troncone, Giancarlo; Chiappetta, Gennaro; Ciardiello, Fortunato; Tortora, Giampaolo; Fagin James, A; Ryan Anderson, J; Carlomagno, Francesca; Santoro, Massimo
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells.
2011 Vitagliano, D; De Falco, V; Tamburrino, A; Coluzzi, S; Troncone, G; Chiappetta, G; Ciardiello, F; Tortora, G; Fagin, Ja; Ryan, Aj; Carlomagno, F; Santoro, M
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells
2010 Salerno, Paolo; De Falco, Valentina; Tamburrino, Anna; Nappi, Tito Claudio; Vecchio, Giancarlo; Schweppe, Rebecca E.; Bollag, Gideon E.; Santoro, Massimo Mattia; Salvátore, Giuliana
The Ca2+-calmodulin-dependent kinase II is activated in papillary thyroid carcinoma (PTC) and mediates cell proliferation stimulated by RET/PTC
2010 Rusciano Maria, Rosaria; Salzano, Marcella; Monaco, Sara; Sapio Maria, Rosaria; Illario, Maddalena; DE FALCO, Valentina; Santoro Massimo, Mattia; Campiglia, Pietro; Pastore, Lucio; Fenzi Gianfranco, F; Rossi, Guido; Vitale Mario, A
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif
2009 Moretti, Sonia; DE FALCO, Valentina; Tamburrino, Anna; Barbi, Flavia; Tavano, Maria; Avenia, N; Santeusanio, Fausto; Santoro Massimo, Mattia; Macchiarulo, Antonio; Puxeddu, Efisio
Molecular genetics of medullary thyroid carcinoma: The quest for novel therapeutic targets
2009 Cerrato, A; De Falco, V; Santoro, ; M,
XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.
2009 M Lodyga; V De Falco; Xh Bai; A Kapus; R M Melillo; M Santoro; M Liu
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics | 1-gen-2023 | Anand, U.; Dey, A.; Chandel, A. K. S.; Sanyal, R.; Mishra, A.; Pandey, D. K.; De Falco, V.; Upadhyay, A.; Kandimalla, R.; Chaudhary, A.; Dhanjal, J. K.; Dewanjee, S.; Vallamkondu, J.; Perez de la Lastra, J. M. | |
p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors | 1-gen-2022 | Maietta, I.; Del Peschio, F.; Buonocore, P.; Viscusi, E.; Laudati, S.; Iannaci, G.; Minopoli, M.; Motti, M. L.; De Falco, V. | |
Targeted Cancer Therapy and Mechanisms of Resistance | 1-gen-2022 | DE FALCO, Valentina | |
The Role of Nutrients in Prevention, Treatment and Post-Coronavirus Disease-2019 (COVID-19) | 1-gen-2022 | Motti, M. L.; Tafuri, D.; Donini, L.; Masucci, M. T.; De Falco, V.; Mazzeo, F. | |
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: Identification of gain-of-function mutations in the RET proto-oncogene | 1-gen-2018 | Mendes Oliveira, D; Grillone, K; Mignogna, C; De Falco, V; Laudanna, C; Biamonte, F; Locane, R; Corcione, F; Fabozzi, M; Sacco, R; Viglietto, G; Malanga, D; Rizzuto, A | |
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer | 1-gen-2017 | De Falco V.; Carlomagno F.; Li H.Y.; Santoro M. | |
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology | 1-gen-2015 | Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu | |
Calcium/calmodulin-dependent protein kinase II and its endogenous inhibitor ? in medullary thyroid cancer. | 1-gen-2014 | Russo, E; Salzano, M; De Falco, V; Mian, C; Barollo, S; Secondo, A; Bifulco, M; Vitale, M | |
Effects of combined administration of rapamycin, tolvaptan and AEZ-131 on progression of polycystic disease in PCK rats. | 1-gen-2014 | Sabbatini, M; Russo, L; Cappellaio, F; Troncone, G; Bellevicine, C; De Falco, V; Buonocore, P; Riccio, E; Bisesti, V; Federico, S; Pisani, A | |
Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer. | 1-gen-2013 | De Falco, V; Buonocore, P; Muthu, M; Torregrossa, L; Basolo, F; Billaud, M; Gozgit, Jm; Carlomagno, F; Santoro, M | |
CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells. | 1-gen-2012 | De Falco V; Tamburrino A; Ventre S; Castellone MD; Malek M; Manié SN; Santoro M. | |
XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt. | 1-gen-2012 | Shiozaki, A; Shentu, G; Bai, X; Iitaka, D; De Falco, V; Santoro, M; Keshavjee, S; Liu, M | |
Mitochondrial Localization and Regulation of BRAF(V600E) in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAF(V600E) | 1-gen-2011 | Lee, Min Hee; Lee, Seong Eun; Kim, Dong Wook; Ryu, Min Jeong; Kim, Sung Jin; Kim, Sung Joong; Kim, Yong Kyoung; Park, Ji Hoon; Kweon, Gi Ryang; Kim, Jin Man; Lee, Jung Uee; De Falco, Valentina; Jo, Young Suk; Shong, Minho | |
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells | 1-gen-2011 | Vitagliano, Donata; DE FALCO, Valentina; Tamburrino, Anna; Coluzzi, Sabrina; Troncone, Giancarlo; Chiappetta, Gennaro; Ciardiello, Fortunato; Tortora, Giampaolo; Fagin James, A; Ryan Anderson, J; Carlomagno, Francesca; Santoro, Massimo | |
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells. | 1-gen-2011 | Vitagliano, D; De Falco, V; Tamburrino, A; Coluzzi, S; Troncone, G; Chiappetta, G; Ciardiello, F; Tortora, G; Fagin, Ja; Ryan, Aj; Carlomagno, F; Santoro, M | |
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells | 1-gen-2010 | Salerno, Paolo; De Falco, Valentina; Tamburrino, Anna; Nappi, Tito Claudio; Vecchio, Giancarlo; Schweppe, Rebecca E.; Bollag, Gideon E.; Santoro, Massimo Mattia; Salvátore, Giuliana | |
The Ca2+-calmodulin-dependent kinase II is activated in papillary thyroid carcinoma (PTC) and mediates cell proliferation stimulated by RET/PTC | 1-gen-2010 | Rusciano Maria, Rosaria; Salzano, Marcella; Monaco, Sara; Sapio Maria, Rosaria; Illario, Maddalena; DE FALCO, Valentina; Santoro Massimo, Mattia; Campiglia, Pietro; Pastore, Lucio; Fenzi Gianfranco, F; Rossi, Guido; Vitale Mario, A | |
Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif | 1-gen-2009 | Moretti, Sonia; DE FALCO, Valentina; Tamburrino, Anna; Barbi, Flavia; Tavano, Maria; Avenia, N; Santeusanio, Fausto; Santoro Massimo, Mattia; Macchiarulo, Antonio; Puxeddu, Efisio | |
Molecular genetics of medullary thyroid carcinoma: The quest for novel therapeutic targets | 1-gen-2009 | Cerrato, A; De Falco, V; Santoro, ; M, | |
XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway. | 1-gen-2009 | M Lodyga; V De Falco; Xh Bai; A Kapus; R M Melillo; M Santoro; M Liu |