CESTRA, GIANLUCA
CESTRA, GIANLUCA
Istituto di Biologia e Patologia Molecolari - IBPM
Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models
2024 Sardina, F.; Carsetti, C.; Giorgini, L.; Fattorini, G.; Cestra, G.; Rinaldo, C.
C9orf72 Toxic Species Affect ArfGAP-1 Function
2023 Rossi, S.; Di Salvio, M.; Bali, M.; De Simone, A.; Apolloni, S.; D'Ambrosi, N.; Arisi, I.; Cipressa, F.; Cozzolino, M.; Cestra, G.
Biallelic mutations in RNF220 cause laminopathies featuring leukodystrophy, ataxia and deafness
2021 Sferra, A; Fortugno, P; Motta, M; Aiello, C; Petrini, S; Ciolfi, A; Cipressa, F; Moroni, I; Leuzzi, V; Pieroni, L; Marini, F; Boespflug Tanguy, O; Eymardpierre, E; Danti, Fr; Compagnucci, C; Zambruno, G; Brusco, A; Santorelli, Fm; Chiapparini, L; Francalanci, P; Loizzo, Al; Tartaglia, M; Cestra, G; Bertini, E
Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model
2021 AzoulayGinsburg S.; Di Salvio M.; Weitman M.; Afri M.; Ribeiro S.; Ebbinghaus S.; Cestra G.; Gruzman A.
A Lipophilic 4-Phenylbutyric Acid Derivative That Prevents Aggregation and Retention of Misfolded Proteins
2020 AzoulayGinsburg, Salome; Trobiani, Laura; Setini, Andrea; Favaloro, Flores Lietta; Giorda, Ezio; Jacob, Avi; Hauschner, Hagit; Levy, Laura; Cestra, Gianluca; De Jaco, Antonella; Gruzman, Arie
HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo
2020 Sanna, Simona; Esposito, Sonia; Masala, Alessandra; Sini, Paola; Nieddu, Gabriele; Galioto, Manuela; Fais, Milena; Iaccarino, Ciro; Cestra, Gianluca; Crosio, Claudia
TUBB Variants Underlying Different Phenotypes Result in Altered Vesicle Trafficking and Microtubule Dynamics
2020 Sferra, Antonella; Petrini, Stefania; Bellacchio, Emanuele; Nicita, Francesco; Scibelli, Francesco; Dentici, Maria Lisa; Alfieri, Paolo; Cestra, Gianluca; Bertini, Enrico Silvio; Zanni, Ginevra
UsnRNP trafficking is regulated by stress granules and compromised by mutant ALS proteins.
2020 Rossi S; Rompietti V; Antonucci Y; Giovannini D; Scopa C; Scaricamazza S; Scardigli R; Cestra G; Serafino A; Carrì MT; D'Ambrosi N; Cozzolino M
Regulation of UsnRNP trafficking by the Integrated Stress Response is compromised by mutant ALS proteins
2019 Rossi, Simona; Rompietti, Valentina; Antonucci, Ylenia; Cestra, Gianluca; Teresa Carrì, Maria; D'Ambrosi, Nadia; Cozzolino, Mauro
SPLICEALS - DISSECTING THE FUNCTIONAL INTERACTION BETWEEN FUS AND HNRNP A2/B1 IN THE PATHOGENESIS OF ALS
2019 Simona Rossi; Savina Apolloni; Michela Di Salvio; Eleonora Mammarella; Martina Milani; Ylenia Antonucci; Assia De Simone; Serena Lattante; Mario Sabatelli; Gianluca Cestra; Nadia D'Ambrosi; Mauro Cozzolino
Recessive mutations in the neuronal isoforms of DST, encoding dystonin, lead to abnormal actin cytoskeleton organization and HSAN type VI
2018 Fortugno, Paola; Angelucci, Francesco; Cestra, Gianluca; Camerota, Letizia; Salvatore Ferraro, Angelo; Cordisco, Sonia; Uccioli, Luigi; Castiglia, Daniele; De Angelis, Barbara; Kurth, Ingo; Kornak, Uwe; Brancati, Francesco
Control of mRNA Translation in ALS Proteinopathy
2017 Cestra, Gianluca; Rossi, Simona; DI SALVIO, Michela; Cozzolino, Mauro
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice
2017 Mirra, Alessia; Rossi, Simona; Scaricamazza, Silvia; Di Salvio, Michela; Salvatori, Illari; Valle, Cristiana; Rusmini, Paola; Poletti, Angelo; Cestra, Gianluca; Carri, Maria Teresa; Cozzolino, Mauro
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice
2017 Mirra, Alessia; Rossi, Simona; Scaricamazza, Silvia; Salvatori, Illari; Valle, Cristiana; Rusmini, Paola; Poletti, Angelo; Cestra, Gianluca; Teresa Carrì, Maria; Cozzolino, Mauro; Di Salvio, Michela
G4C2 repeat affects nuclear mRNA export pathway in a cellular model of C9orf72-ALS
2016 ROSSI S ; SERRANO A ; MIRRA A ; CESTRA G ; CARRÌ MT ; ; COZZOLINO M ;
nArgBP2 regulates excitatory synapse formation by controlling dendritic spine morphology
2016 Lee, Sangeun; Kim, Yoonju; Han, Jeongkyu; Park, Hoyong; Lee, Unghwi; Na, Myeongsu; Jeong, Soomin; Chung, Chihye; Cestra, Gianluca; Chang, Sunghoe
Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS
2015 Rossi, S; Serrano, A; Gerbino, V; Giorgi, A; Di Francesco, L; Nencini, M; Bozzo, F; Schinina, Me; Bagni, C; Cestra, G; Carri, Mt; Achsel, T; Cozzolino, M
Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.
2015 DI SALVIO, Michela; Piccinni, V; Gerbino, V; Mantoni, F; Camerini, S; Lenzi, J; Rosa, A; Chellini, L; Loreni, F; T Carrì, M; Bozzoni, I; Cozzolino, M; Cestra, G
Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.
2015 Piccinni, Violetta; Gerbino, Valeria; Mantoni, Federico; Camerini, Serena; Lenzi, Jessica; Rosa, Alessandro; Chellini, Lidia; Loreni, Fabrizio; Teresa Carrì, Maria; Bozzoni, Irene; Cozzolino, Mauro; Cestra, Gianluca; Di Salvio, Michela
Translational repression in the pathogenesis of FUS- and C9orf72-dependent ALS
2015 Cozzolino, Mauro; Rossi, Simona; Cestra, Gianluca
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models | 1-gen-2024 | Sardina, F.; Carsetti, C.; Giorgini, L.; Fattorini, G.; Cestra, G.; Rinaldo, C. | |
| C9orf72 Toxic Species Affect ArfGAP-1 Function | 1-gen-2023 | Rossi, S.; Di Salvio, M.; Bali, M.; De Simone, A.; Apolloni, S.; D'Ambrosi, N.; Arisi, I.; Cipressa, F.; Cozzolino, M.; Cestra, G. | |
| Biallelic mutations in RNF220 cause laminopathies featuring leukodystrophy, ataxia and deafness | 1-gen-2021 | Sferra, A; Fortugno, P; Motta, M; Aiello, C; Petrini, S; Ciolfi, A; Cipressa, F; Moroni, I; Leuzzi, V; Pieroni, L; Marini, F; Boespflug Tanguy, O; Eymardpierre, E; Danti, Fr; Compagnucci, C; Zambruno, G; Brusco, A; Santorelli, Fm; Chiapparini, L; Francalanci, P; Loizzo, Al; Tartaglia, M; Cestra, G; Bertini, E | |
| Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model | 1-gen-2021 | AzoulayGinsburg S.; Di Salvio M.; Weitman M.; Afri M.; Ribeiro S.; Ebbinghaus S.; Cestra G.; Gruzman A. | |
| A Lipophilic 4-Phenylbutyric Acid Derivative That Prevents Aggregation and Retention of Misfolded Proteins | 1-gen-2020 | AzoulayGinsburg, Salome; Trobiani, Laura; Setini, Andrea; Favaloro, Flores Lietta; Giorda, Ezio; Jacob, Avi; Hauschner, Hagit; Levy, Laura; Cestra, Gianluca; De Jaco, Antonella; Gruzman, Arie | |
| HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo | 1-gen-2020 | Sanna, Simona; Esposito, Sonia; Masala, Alessandra; Sini, Paola; Nieddu, Gabriele; Galioto, Manuela; Fais, Milena; Iaccarino, Ciro; Cestra, Gianluca; Crosio, Claudia | |
| TUBB Variants Underlying Different Phenotypes Result in Altered Vesicle Trafficking and Microtubule Dynamics | 1-gen-2020 | Sferra, Antonella; Petrini, Stefania; Bellacchio, Emanuele; Nicita, Francesco; Scibelli, Francesco; Dentici, Maria Lisa; Alfieri, Paolo; Cestra, Gianluca; Bertini, Enrico Silvio; Zanni, Ginevra | |
| UsnRNP trafficking is regulated by stress granules and compromised by mutant ALS proteins. | 1-gen-2020 | Rossi S; Rompietti V; Antonucci Y; Giovannini D; Scopa C; Scaricamazza S; Scardigli R; Cestra G; Serafino A; Carrì MT; D'Ambrosi N; Cozzolino M | |
| Regulation of UsnRNP trafficking by the Integrated Stress Response is compromised by mutant ALS proteins | 1-gen-2019 | Rossi, Simona; Rompietti, Valentina; Antonucci, Ylenia; Cestra, Gianluca; Teresa Carrì, Maria; D'Ambrosi, Nadia; Cozzolino, Mauro | |
| SPLICEALS - DISSECTING THE FUNCTIONAL INTERACTION BETWEEN FUS AND HNRNP A2/B1 IN THE PATHOGENESIS OF ALS | 1-gen-2019 | Simona Rossi; Savina Apolloni; Michela Di Salvio; Eleonora Mammarella; Martina Milani; Ylenia Antonucci; Assia De Simone; Serena Lattante; Mario Sabatelli; Gianluca Cestra; Nadia D'Ambrosi; Mauro Cozzolino | |
| Recessive mutations in the neuronal isoforms of DST, encoding dystonin, lead to abnormal actin cytoskeleton organization and HSAN type VI | 1-gen-2018 | Fortugno, Paola; Angelucci, Francesco; Cestra, Gianluca; Camerota, Letizia; Salvatore Ferraro, Angelo; Cordisco, Sonia; Uccioli, Luigi; Castiglia, Daniele; De Angelis, Barbara; Kurth, Ingo; Kornak, Uwe; Brancati, Francesco | |
| Control of mRNA Translation in ALS Proteinopathy | 1-gen-2017 | Cestra, Gianluca; Rossi, Simona; DI SALVIO, Michela; Cozzolino, Mauro | |
| Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice | 1-gen-2017 | Mirra, Alessia; Rossi, Simona; Scaricamazza, Silvia; Di Salvio, Michela; Salvatori, Illari; Valle, Cristiana; Rusmini, Paola; Poletti, Angelo; Cestra, Gianluca; Carri, Maria Teresa; Cozzolino, Mauro | |
| Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice | 1-gen-2017 | Mirra, Alessia; Rossi, Simona; Scaricamazza, Silvia; Salvatori, Illari; Valle, Cristiana; Rusmini, Paola; Poletti, Angelo; Cestra, Gianluca; Teresa Carrì, Maria; Cozzolino, Mauro; Di Salvio, Michela | |
| G4C2 repeat affects nuclear mRNA export pathway in a cellular model of C9orf72-ALS | 1-gen-2016 | ROSSI S ; SERRANO A ; MIRRA A ; CESTRA G ; CARRÌ MT ; ; COZZOLINO M ; | |
| nArgBP2 regulates excitatory synapse formation by controlling dendritic spine morphology | 1-gen-2016 | Lee, Sangeun; Kim, Yoonju; Han, Jeongkyu; Park, Hoyong; Lee, Unghwi; Na, Myeongsu; Jeong, Soomin; Chung, Chihye; Cestra, Gianluca; Chang, Sunghoe | |
| Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS | 1-gen-2015 | Rossi, S; Serrano, A; Gerbino, V; Giorgi, A; Di Francesco, L; Nencini, M; Bozzo, F; Schinina, Me; Bagni, C; Cestra, G; Carri, Mt; Achsel, T; Cozzolino, M | |
| Pur-alpha functionally interacts with FUS carrying ALS-associated mutations. | 1-gen-2015 | DI SALVIO, Michela; Piccinni, V; Gerbino, V; Mantoni, F; Camerini, S; Lenzi, J; Rosa, A; Chellini, L; Loreni, F; T Carrì, M; Bozzoni, I; Cozzolino, M; Cestra, G | |
| Pur-alpha functionally interacts with FUS carrying ALS-associated mutations. | 1-gen-2015 | Piccinni, Violetta; Gerbino, Valeria; Mantoni, Federico; Camerini, Serena; Lenzi, Jessica; Rosa, Alessandro; Chellini, Lidia; Loreni, Fabrizio; Teresa Carrì, Maria; Bozzoni, Irene; Cozzolino, Mauro; Cestra, Gianluca; Di Salvio, Michela | |
| Translational repression in the pathogenesis of FUS- and C9orf72-dependent ALS | 1-gen-2015 | Cozzolino, Mauro; Rossi, Simona; Cestra, Gianluca |