DE ROSA, MATTEO
DE ROSA, MATTEO
Istituto di Biofisica - IBF
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint
2023 Guay Kevin, P.; Ibba, Roberta; Kiappes, J. L.; Vasiljević, Snezana; Bonì, Francesco; DE BENEDICTIS, Maria; Zeni, Ilaria; Le Cornu James, D.; Hensen, Mario; Chandran Anu, V.; Kantsadi Anastassia, L.; Caputo Alessandro, T.; Blanco Capurro Juan, I.; Bayo, Yusupha; Hill Johan, C.; Hudson, Kieran; Lia, Andrea; Brun, Juliane; Withers Stephen, G.; Martí, Marcelo; Biasini, Emiliano; Santino, Angelo; DE ROSA, Matteo; MILANI DE MAYO DE MARI, Mario; Modenutti Carlos, P.; Hebert Daniel, N.; Zitzmann, Nicole; Roversi, Pietro
Rational Design of a Peptidomimetic Inhibitor of Gelsolin Amyloid Aggregation
2022 Bollati, M; Peqini, K; Barone, L; Natale, C; Beeg, M; Gobbi, M; Diomede, L; Trucchi, M; de Rosa, M; Pellegrino, S
A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation
2021 Bollati, Michela; Diomede, Luisa; Giorgino, Toni; Natale, Carmina; Fagnani, Elisa; Boniardi, Irene; Barbiroli, Alberto; Alemani, Rebecca; Beeg, Marten; Gobbi, Marco; Fakin, Ana; Mastrangelo, Eloise; MILANI DE MAYO DE MARI, Mario; Presciuttini, Gianluca; Gabellieri, Edi; Cioni, Patrizia; DE ROSA, Matteo
Clinical and histopathological features of gelsolin amyloidosis associated with a novel gsn variant p.Glu580lys
2021 Potrc, M; Volk, M; de Rosa, M; Pizem, J; Teran, N; Jaklic, H; Maver, A; Drnovsekolup, B; Bollati, M; Vogelnik, K; Hocevar, A; Gornik, A; Pfeifer, V; Peterlin, B; Hawlina, M; Fakin, A
Covalent inhibition of P. falciparum ferredoxin-NADP plus reductase: Exploring alternative strategies for the development of new antimalarial drugs
2021 Rosa, De; DE ROSA, Matteo; Nonnis, ; Simona, ; Aliverti, ; Alessandro,
The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties
2020 De Rosa Matteo; Barbiroli Alberto; Bonì Francesco; Scalone Emanuele; Mattioni Davide; Vanoni Maria A.; Patrone Marco; Bollati Michela; Mastrangelo Eloise; Giorgino Toni; Milani Mario
An alternative non-proteolytic mechanism may underlie AGel amyloidosis
2019 Bonì F; Milani M; Mastrangelo E; Babiroli A; Diomede L; de Rosa M
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion
2019 Bollati, M; Scalone, E; Bonì, F; Mastrangelo, E; Giorgino, T; Milani, M; de Rosa, M
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant
2019 Giorgino, T; Mattioni, D; Hassan, A; Milani, M; Mastrangelo, E; Barbiroli, A; Verhelle, A; Gettemans, J; Barzago, Mm; Diomede, L; de Rosa, M
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
2018 Le Marchand T.; De Rosa M.; Salvi N.; Sala B.M.; Andreas L.B.; BarbetMassin E.; Sormanni P.; Barbiroli A.; Porcari R.; Sousa Mota C.; De Sanctis D.; Bolognesi M.; Emsley L.; Bellotti V.; Blackledge M.; Camilloni C.; Pintacuda G.; Ricagno S.
Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein
2018 Bonì, F; Milani, M; Barbiroli, A; Diomede, L; Mastrangelo, E; de Rosa, M
Identification of a small molecule that compromises the structural integrity of viroplasms and rotavirus double-layered particles
2018 Eichwald C; De Lorenzo G; Schraner EM; Papa G; Bollati M; Swuec P; de Rosa M; Milani M; Mastrangelo E; Ackermann M; Burrone OR; Arnoldi F
Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs
2018 Corti A; Milani M; Lecis D; Seneci P; de Rosa M; Mastrangelo E; Cossu F
An Asp to Asn mutation is a toxic trigger in beta-2 microglobulin: structure and biophysics
2017 de Rosa M; Halabelian L; Barbiroli A; Bolognesi M; Bellotti V; Ricagno S
Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice
2017 Brambilla, V; Martignago, D; Goretti, D; Cerise, M; Somssich, M; de Rosa, M; Galbiati, F; Shrestha, R; Lazzaro, F; Simon, R; Fornara, F
Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant
2016 Bonì F; Milani M; Porcari R; Barbiroli A; Ricagno S; de Rosa M
Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability
2016 Camilloni C; Sala BM; Sormanni P; Porcari R; Corazza A; De Rosa M; Zanini S; Barbiroli A; Esposito G; Bolognesi M; Bellotti V; Vendruscolo M; Ricagno S
Decoding the Structural Bases of D76N beta 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis
2015 DE ROSA, Matteo; Barbiroli, Alberto; Giorgetti, Sofia; Mangione Patrizia, P; Bolognesi, Martino; Ricagno, Stefano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint | 1-gen-2023 | Guay Kevin, P.; Ibba, Roberta; Kiappes, J. L.; Vasiljević, Snezana; Bonì, Francesco; DE BENEDICTIS, Maria; Zeni, Ilaria; Le Cornu James, D.; Hensen, Mario; Chandran Anu, V.; Kantsadi Anastassia, L.; Caputo Alessandro, T.; Blanco Capurro Juan, I.; Bayo, Yusupha; Hill Johan, C.; Hudson, Kieran; Lia, Andrea; Brun, Juliane; Withers Stephen, G.; Martí, Marcelo; Biasini, Emiliano; Santino, Angelo; DE ROSA, Matteo; MILANI DE MAYO DE MARI, Mario; Modenutti Carlos, P.; Hebert Daniel, N.; Zitzmann, Nicole; Roversi, Pietro | |
| Rational Design of a Peptidomimetic Inhibitor of Gelsolin Amyloid Aggregation | 1-gen-2022 | Bollati, M; Peqini, K; Barone, L; Natale, C; Beeg, M; Gobbi, M; Diomede, L; Trucchi, M; de Rosa, M; Pellegrino, S | |
| A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation | 1-gen-2021 | Bollati, Michela; Diomede, Luisa; Giorgino, Toni; Natale, Carmina; Fagnani, Elisa; Boniardi, Irene; Barbiroli, Alberto; Alemani, Rebecca; Beeg, Marten; Gobbi, Marco; Fakin, Ana; Mastrangelo, Eloise; MILANI DE MAYO DE MARI, Mario; Presciuttini, Gianluca; Gabellieri, Edi; Cioni, Patrizia; DE ROSA, Matteo | |
| Clinical and histopathological features of gelsolin amyloidosis associated with a novel gsn variant p.Glu580lys | 1-gen-2021 | Potrc, M; Volk, M; de Rosa, M; Pizem, J; Teran, N; Jaklic, H; Maver, A; Drnovsekolup, B; Bollati, M; Vogelnik, K; Hocevar, A; Gornik, A; Pfeifer, V; Peterlin, B; Hawlina, M; Fakin, A | |
| Covalent inhibition of P. falciparum ferredoxin-NADP plus reductase: Exploring alternative strategies for the development of new antimalarial drugs | 1-gen-2021 | Rosa, De; DE ROSA, Matteo; Nonnis, ; Simona, ; Aliverti, ; Alessandro, | |
| The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties | 1-gen-2020 | De Rosa Matteo; Barbiroli Alberto; Bonì Francesco; Scalone Emanuele; Mattioni Davide; Vanoni Maria A.; Patrone Marco; Bollati Michela; Mastrangelo Eloise; Giorgino Toni; Milani Mario | |
| An alternative non-proteolytic mechanism may underlie AGel amyloidosis | 1-gen-2019 | Bonì F; Milani M; Mastrangelo E; Babiroli A; Diomede L; de Rosa M | |
| High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion | 1-gen-2019 | Bollati, M; Scalone, E; Bonì, F; Mastrangelo, E; Giorgino, T; Milani, M; de Rosa, M | |
| Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant | 1-gen-2019 | Giorgino, T; Mattioni, D; Hassan, A; Milani, M; Mastrangelo, E; Barbiroli, A; Verhelle, A; Gettemans, J; Barzago, Mm; Diomede, L; de Rosa, M | |
| Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity | 1-gen-2018 | Le Marchand T.; De Rosa M.; Salvi N.; Sala B.M.; Andreas L.B.; BarbetMassin E.; Sormanni P.; Barbiroli A.; Porcari R.; Sousa Mota C.; De Sanctis D.; Bolognesi M.; Emsley L.; Bellotti V.; Blackledge M.; Camilloni C.; Pintacuda G.; Ricagno S. | |
| Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein | 1-gen-2018 | Bonì, F; Milani, M; Barbiroli, A; Diomede, L; Mastrangelo, E; de Rosa, M | |
| Identification of a small molecule that compromises the structural integrity of viroplasms and rotavirus double-layered particles | 1-gen-2018 | Eichwald C; De Lorenzo G; Schraner EM; Papa G; Bollati M; Swuec P; de Rosa M; Milani M; Mastrangelo E; Ackermann M; Burrone OR; Arnoldi F | |
| Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs | 1-gen-2018 | Corti A; Milani M; Lecis D; Seneci P; de Rosa M; Mastrangelo E; Cossu F | |
| An Asp to Asn mutation is a toxic trigger in beta-2 microglobulin: structure and biophysics | 1-gen-2017 | de Rosa M; Halabelian L; Barbiroli A; Bolognesi M; Bellotti V; Ricagno S | |
| Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice | 1-gen-2017 | Brambilla, V; Martignago, D; Goretti, D; Cerise, M; Somssich, M; de Rosa, M; Galbiati, F; Shrestha, R; Lazzaro, F; Simon, R; Fornara, F | |
| Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant | 1-gen-2016 | Bonì F; Milani M; Porcari R; Barbiroli A; Ricagno S; de Rosa M | |
| Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability | 1-gen-2016 | Camilloni C; Sala BM; Sormanni P; Porcari R; Corazza A; De Rosa M; Zanini S; Barbiroli A; Esposito G; Bolognesi M; Bellotti V; Vendruscolo M; Ricagno S | |
| Decoding the Structural Bases of D76N beta 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis | 1-gen-2015 | DE ROSA, Matteo; Barbiroli, Alberto; Giorgetti, Sofia; Mangione Patrizia, P; Bolognesi, Martino; Ricagno, Stefano |