Di Spiezio, Alessandro
Di Spiezio, Alessandro
Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis
2021 Di Spiezio, Alessandro; Marques, André R.A.; Schmidt, Lina; Thießen, Niklas; Gallwitz, Lisa; Fogh, Jens; Bartsch, Udo; Saftig, Paul
Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease
2022 Gallwitz, Lisa; Schmidt, Lina; Marques André, Ra; Tholey, Andreas; Cassidy, Liam; Ulku, Irem; Multhaup, Gerhard; Di Spiezio, Alessandro; Saftig, Paul
Endothelial LRP1 transports amyloid-?1-42 across the blood-brain barrier
2016 Storck, Steffen E.; Meister, Sabrina; Nahrath, Julius; Meißner, Julius N.; Schubert, Nils; Di Spiezio, Alessandro; Baches, Sandra; Vandenbroucke, Roosmarijn E.; Bouter, Yvonne; Prikulis, Ingrid; Korth, Carsten; Weggen, Sascha; Heimann, Axel; Schwaninger, Markus; Bayer, Thomas A.; Pietrzik, Claus U.
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis
2020 Marques André, Ra; Di Spiezio, Alessandro; Thießen, Niklas; Schmidt, Lina; Grötzinger, Joachim; Lüllmannrauch, Renate; Damme, Markus; Storck Steffen, E; Pietrzik Claus, U; Fogh, Jens; Bär, Julia; Mikhaylova, Marina; Glatzel, Markus; Bassal, Mahmoud; Bartsch, Udo; Saftig, Paul
Intravitreal gene therapy restores the autophagy-lysosomal pathway and attenuates retinal degeneration in cathepsin D-deficient mice
2022 Liu, Junling; Bassal, Mahmoud; Schlichting, Stefanie; Braren, Ingke; Di Spiezio, Alessandro; Saftig, Paul; Bartsch, Udo
Ion Channels and Ionotropic Receptors in Astrocytes: Physiological Functions and Alterations in Alzheimer's Disease and Glioblastoma
2023 Lia, Annamaria; Di Spiezio, Alessandro; Vitalini, Lorenzo; Tore, Manuela; Puja, Giulia; Losi, Gabriele
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 Pedram, Kayvon; Laqtom Nouf, N; Shon, D Judy; Di Spiezio, Alessandro; Riley Nicholas, M; Saftig, Paul; Aburemaileh, Monther; Bertozzi Carolyn, R
Mechanisms of amyloid-?34 generation indicate a pivotal role for BACE1 in amyloid homeostasis
2023 Ulku, Irem; Liebsch, Filip; Akerman, S. Can; Schulz, Jana F.; Kulic, Luka; Hock, Christoph; Pietrzik, Claus; Di Spiezio, Alessandro; Thinakaran, Gopal; Saftig, Paul; Multhaup, Gerhard
Nesfatin-1 decreases the motivational and rewarding value of food
2020 Dore R.; Krotenko R.; Reising J.P.; Murru L.; Sundaram S.M.; Di Spiezio A.; MullerFielitz H.; Schwaninger M.; Johren O.; Mittag J.; Passafaro M.; Shanabrough M.; Horvath T.L.; Schulz C.; Lehnert H.
Recombinant pro-CTSD (cathepsin D) enhances SNCA/?-Synuclein degradation in ?-Synucleinopathy models
2022 Prieto Huarcaya, Susy; Drobny, Alice; Marques, André R.A.; Di Spiezio, Alessandro; Dobert, Jan Philipp; Balta, Denise; Werner, Christian; Rizo, Tania; Gallwitz, Lisa; Bub, Simon; Stojkovska, Iva; Belur, Nandkishore R.; Fogh, Jens; Mazzulli, Joseph R.; Xiang, Wei; Fulzele, Amitkumar; Dejung, Mario; Sauer, Markus; Winner, Beate; RoseJohn, Stefan; Arnold, Philipp; Saftig, Paul; Zunke, Friederike
The LepR-mediated leptin transport across brain barriers controls food reward
2018 Di Spiezio, Alessandro; Sandin, Elvira Sonia; Dore, Riccardo; MüllerFielitz, Helge; Storck, Steffen E.; Bernau, Mareike; Mier, Walter; Oster, Henrik; Jöhren, Olaf; Pietrzik, Claus U.; Lehnert, Hendrik; Schwaninger, Markus
Two decades of astrocytes in neurovascular coupling
2023 Lia, Annamaria;Di Spiezio, Alessandro; Speggiorin, Michele; Zonta, Micaela
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis | 1-gen-2021 | Di Spiezio, Alessandro; Marques, André R.A.; Schmidt, Lina; Thießen, Niklas; Gallwitz, Lisa; Fogh, Jens; Bartsch, Udo; Saftig, Paul | |
| Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease | 1-gen-2022 | Gallwitz, Lisa; Schmidt, Lina; Marques André, Ra; Tholey, Andreas; Cassidy, Liam; Ulku, Irem; Multhaup, Gerhard; Di Spiezio, Alessandro; Saftig, Paul | |
| Endothelial LRP1 transports amyloid-?1-42 across the blood-brain barrier | 1-gen-2016 | Storck, Steffen E.; Meister, Sabrina; Nahrath, Julius; Meißner, Julius N.; Schubert, Nils; Di Spiezio, Alessandro; Baches, Sandra; Vandenbroucke, Roosmarijn E.; Bouter, Yvonne; Prikulis, Ingrid; Korth, Carsten; Weggen, Sascha; Heimann, Axel; Schwaninger, Markus; Bayer, Thomas A.; Pietrzik, Claus U. | |
| Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis | 1-gen-2020 | Marques André, Ra; Di Spiezio, Alessandro; Thießen, Niklas; Schmidt, Lina; Grötzinger, Joachim; Lüllmannrauch, Renate; Damme, Markus; Storck Steffen, E; Pietrzik Claus, U; Fogh, Jens; Bär, Julia; Mikhaylova, Marina; Glatzel, Markus; Bassal, Mahmoud; Bartsch, Udo; Saftig, Paul | |
| Intravitreal gene therapy restores the autophagy-lysosomal pathway and attenuates retinal degeneration in cathepsin D-deficient mice | 1-gen-2022 | Liu, Junling; Bassal, Mahmoud; Schlichting, Stefanie; Braren, Ingke; Di Spiezio, Alessandro; Saftig, Paul; Bartsch, Udo | |
| Ion Channels and Ionotropic Receptors in Astrocytes: Physiological Functions and Alterations in Alzheimer's Disease and Glioblastoma | 1-gen-2023 | Lia, Annamaria; Di Spiezio, Alessandro; Vitalini, Lorenzo; Tore, Manuela; Puja, Giulia; Losi, Gabriele | |
| Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals | 1-gen-2022 | Pedram, Kayvon; Laqtom Nouf, N; Shon, D Judy; Di Spiezio, Alessandro; Riley Nicholas, M; Saftig, Paul; Aburemaileh, Monther; Bertozzi Carolyn, R | |
| Mechanisms of amyloid-?34 generation indicate a pivotal role for BACE1 in amyloid homeostasis | 1-gen-2023 | Ulku, Irem; Liebsch, Filip; Akerman, S. Can; Schulz, Jana F.; Kulic, Luka; Hock, Christoph; Pietrzik, Claus; Di Spiezio, Alessandro; Thinakaran, Gopal; Saftig, Paul; Multhaup, Gerhard | |
| Nesfatin-1 decreases the motivational and rewarding value of food | 1-gen-2020 | Dore R.; Krotenko R.; Reising J.P.; Murru L.; Sundaram S.M.; Di Spiezio A.; MullerFielitz H.; Schwaninger M.; Johren O.; Mittag J.; Passafaro M.; Shanabrough M.; Horvath T.L.; Schulz C.; Lehnert H. | |
| Recombinant pro-CTSD (cathepsin D) enhances SNCA/?-Synuclein degradation in ?-Synucleinopathy models | 1-gen-2022 | Prieto Huarcaya, Susy; Drobny, Alice; Marques, André R.A.; Di Spiezio, Alessandro; Dobert, Jan Philipp; Balta, Denise; Werner, Christian; Rizo, Tania; Gallwitz, Lisa; Bub, Simon; Stojkovska, Iva; Belur, Nandkishore R.; Fogh, Jens; Mazzulli, Joseph R.; Xiang, Wei; Fulzele, Amitkumar; Dejung, Mario; Sauer, Markus; Winner, Beate; RoseJohn, Stefan; Arnold, Philipp; Saftig, Paul; Zunke, Friederike | |
| The LepR-mediated leptin transport across brain barriers controls food reward | 1-gen-2018 | Di Spiezio, Alessandro; Sandin, Elvira Sonia; Dore, Riccardo; MüllerFielitz, Helge; Storck, Steffen E.; Bernau, Mareike; Mier, Walter; Oster, Henrik; Jöhren, Olaf; Pietrzik, Claus U.; Lehnert, Hendrik; Schwaninger, Markus | |
| Two decades of astrocytes in neurovascular coupling | 1-gen-2023 | Lia, Annamaria;Di Spiezio, Alessandro; Speggiorin, Michele; Zonta, Micaela |