DE SIMONE, GIUSEPPINA
DE SIMONE, GIUSEPPINA
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
Anticancer drugs: where are we now?
2024 De Simone, Giuseppina; Supuran, Claudiu T.
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography
2023 Nocentini, Alessio; Bonardi, Alessandro; Bazzicalupi, Carla; Alterio, Vincenzo; Esposito, Davide; Monti, SIMONA MARIA; Smietana, Michael; DE SIMONE, Giuseppina; Supuran, Claudiu T.; Gratteri, Paola; Winum, Jean-Yves
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
2023 Langella, Emma; Esposito, Davide; Monti, SIMONA MARIA; Supuran, Claudiu T.; DE SIMONE, Giuseppina; Alterio, Vincenzo
Carbonic anhydrase IX subcellular localization in normoxic and hypoxic SH-SY5Y neuroblastoma cells is assisted by its C-terminal protein interaction domain
2023 Succoio, Mariangela; Amiranda, Sara; Sasso, Emanuele; Marciano, Carmen; Finizio, Arianna; De Simone, Giuseppina; Garbi, Corrado; Zambrano, Nicola
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for mi-Opioid receptor for Safer and long-lasting analgesia
2023 Angeli, Andrea; Micheli, Laura; Turnaturi, Rita; Pasquinucci, Lorella; Parenti, Carmela; Alterio, Vincenzo; DI FIORE, Anna; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Carta, Fabrizio; Mannelli Lorenzo Di, Cesare; Ghelardini, Carla; Supuran Claudiu, T
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells
2023 Sarnella, Annachiara; Ferrara, Ylenia; Albanese, Sandra; Omodei, Daniela; Cerchia, Laura; De Simone, Giuseppina; Supuran, Claudiu T; Zannetti, Antonella
Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1
2022 Ayoub, Joëlle; Buonanno, Martina; Di Fiore, Anna; De Simone, Giuseppina; Monti, Simona Maria
Biochemical, structural, and computational studies of a ?-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei
2022 Di Fiore, A; De Luca, V; Langella, E; Nocentini, A; Buonanno, M; Monti, Sm; Supuran, Ct; Capasso, C; De Simone, G
Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
2022 Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella
Post-translational modifications in tumor-associated carbonic anhydrases
2022 DI FIORE, Anna; T Supuran, Claudiu; Scaloni, Andrea; DE SIMONE, Giuseppina
Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain
2022 Akgül, Özlem; Lucarini, Elena; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; D'Ambrosio, Katia; Buonanno, Martina; Monti, Simona Maria; De Simone, Giuseppina; Angeli, Andrea; Supuran, Claudiu T.; Carta, Fabrizio
α-CAs from Photosynthetic Organisms
2022 Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
2021 De Simone, G; Bua, S; Supuran, Ct; Alterio, V
Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides
2021 Urbański, Linda J.; Angeli, Andrea; Hytönen, Vesa P.; Di Fiore, Anna; De Simone, Giuseppina; Parkkila, Seppo; Supuran, Claudiu T.
Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain
2021 Langella, Emma; Buonanno, Martina; DE SIMONE, Giuseppina; Monti, SIMONA MARIA
The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development
2021 D'Ambrosio, Katia; DI FIORE, Anna; Buonanno, Martina; Kumari, Shikha; Tiwari, Manisha; Supuran Claudiu, T; Mishra Chandra, Bhushan; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
2021 Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag, Murat; Supuran Claudiu, T; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; Alterio, Vincenzo
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
2020 Sarnella, Annachiara; D'Avino, Giuliana; Hill, Billy Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella
Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis
2020 Urbanski Linda, J; DI FIORE, Anna; Azizi, Latifeh; Hytonen Vesa, P; Kuuslahti, Marianne; Buonanno, Martina; Monti Simona, M; Angeli, Andrea; Emameh Reza, Zolfaghari; Supuran Claudiu, T; DE SIMONE, Giuseppina; Parkkila, Seppo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Anticancer drugs: where are we now? | 1-gen-2024 | De Simone, Giuseppina; Supuran, Claudiu T. | |
| 6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography | 1-gen-2023 | Nocentini, Alessio; Bonardi, Alessandro; Bazzicalupi, Carla; Alterio, Vincenzo; Esposito, Davide; Monti, SIMONA MARIA; Smietana, Michael; DE SIMONE, Giuseppina; Supuran, Claudiu T.; Gratteri, Paola; Winum, Jean-Yves | |
| A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors | 1-gen-2023 | Langella, Emma; Esposito, Davide; Monti, SIMONA MARIA; Supuran, Claudiu T.; DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| Carbonic anhydrase IX subcellular localization in normoxic and hypoxic SH-SY5Y neuroblastoma cells is assisted by its C-terminal protein interaction domain | 1-gen-2023 | Succoio, Mariangela; Amiranda, Sara; Sasso, Emanuele; Marciano, Carmen; Finizio, Arianna; De Simone, Giuseppina; Garbi, Corrado; Zambrano, Nicola | |
| Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for mi-Opioid receptor for Safer and long-lasting analgesia | 1-gen-2023 | Angeli, Andrea; Micheli, Laura; Turnaturi, Rita; Pasquinucci, Lorella; Parenti, Carmela; Alterio, Vincenzo; DI FIORE, Anna; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Carta, Fabrizio; Mannelli Lorenzo Di, Cesare; Ghelardini, Carla; Supuran Claudiu, T | |
| Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells | 1-gen-2023 | Sarnella, Annachiara; Ferrara, Ylenia; Albanese, Sandra; Omodei, Daniela; Cerchia, Laura; De Simone, Giuseppina; Supuran, Claudiu T; Zannetti, Antonella | |
| Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1 | 1-gen-2022 | Ayoub, Joëlle; Buonanno, Martina; Di Fiore, Anna; De Simone, Giuseppina; Monti, Simona Maria | |
| Biochemical, structural, and computational studies of a ?-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei | 1-gen-2022 | Di Fiore, A; De Luca, V; Langella, E; Nocentini, A; Buonanno, M; Monti, Sm; Supuran, Ct; Capasso, C; De Simone, G | |
| Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion | 1-gen-2022 | Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella | |
| Post-translational modifications in tumor-associated carbonic anhydrases | 1-gen-2022 | DI FIORE, Anna; T Supuran, Claudiu; Scaloni, Andrea; DE SIMONE, Giuseppina | |
| Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain | 1-gen-2022 | Akgül, Özlem; Lucarini, Elena; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; D'Ambrosio, Katia; Buonanno, Martina; Monti, Simona Maria; De Simone, Giuseppina; Angeli, Andrea; Supuran, Claudiu T.; Carta, Fabrizio | |
| α-CAs from Photosynthetic Organisms | 1-gen-2022 | Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia | |
| Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule | 1-gen-2021 | De Simone, G; Bua, S; Supuran, Ct; Alterio, V | |
| Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides | 1-gen-2021 | Urbański, Linda J.; Angeli, Andrea; Hytönen, Vesa P.; Di Fiore, Anna; De Simone, Giuseppina; Parkkila, Seppo; Supuran, Claudiu T. | |
| Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain | 1-gen-2021 | Langella, Emma; Buonanno, Martina; DE SIMONE, Giuseppina; Monti, SIMONA MARIA | |
| The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development | 1-gen-2021 | D'Ambrosio, Katia; DI FIORE, Anna; Buonanno, Martina; Kumari, Shikha; Tiwari, Manisha; Supuran Claudiu, T; Mishra Chandra, Bhushan; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? | 1-gen-2021 | Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site | 1-gen-2020 | Bozdag, Murat; Supuran Claudiu, T; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity | 1-gen-2020 | Sarnella, Annachiara; D'Avino, Giuliana; Hill, Billy Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella | |
| Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis | 1-gen-2020 | Urbanski Linda, J; DI FIORE, Anna; Azizi, Latifeh; Hytonen Vesa, P; Kuuslahti, Marianne; Buonanno, Martina; Monti Simona, M; Angeli, Andrea; Emameh Reza, Zolfaghari; Supuran Claudiu, T; DE SIMONE, Giuseppina; Parkkila, Seppo |