DE SIMONE, GIUSEPPINA
DE SIMONE, GIUSEPPINA
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
(In)organic anions as carbonic anhydrase inhibitors
2012 De Simone G; Supuran CT.
-RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications
2009 Alterio, V; Di Fiore, A; Dambrosio, K; T Supuran, C; DE SIMONE, Giuseppina
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo
2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity
2006 M. P. Leese; B. LeBlond; S. P. Newman; A. Di Fiore; G. De Simone; C. T. Supuran; A. Purohit; M. J. Reed; B. V. L. Potter.
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases
2016 Langella, Emma; D'Ambrosio, Katia; D'Ascenzio, Melissa; Carradori, Simone; Monti, Simona M.; Supuran, Claudiu T.; De Simone, Giuseppina
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
2023 Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo
A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY
2010 Pirone, L; Correale, S; DI GAETANO, Sonia; De Paola, I; Zaccaro, L; DE SIMONE, Giuseppina; Vitagliano, L; Pedone, C; Pedone, E
A NEW LEAD COMPOUND FOR THE DEVELOPMENT OF CARBONIC ANHYDRASE INHIBITORS
2015 Giuseppina De Simone; Alessandro Vergara; Marco Caterino; Vincenzo Alterio; Simona M. Monti; Joanna Ombouma; Pascal Dumy; Daniela Vullo; Claudiu T. Supuran; JeanYves Winum; Anna Di Fiore.
A new role of Human Carbonic Anhydrase VII in the protection of the cells from oxidative damage
2013 Monti, Dm; Del Giudice, R; Sandomenico, A; Buonanno, M; Supuran, Ct; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
2020 Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella
A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics.
2006 D'Ambrosio, Katia; Pedone, EMILIA MARIA; Langella, Emma; DE SIMONE, Giuseppina; Rossi, Mose'; Pedone, Carlo; Bartolucci, Simonetta
A substrate-induced switch in the reaction mechanism of a thermophilic esterase. Kinetic evidences and structutal basis
2004 De Simone, G; Mandrich, L; Menchise, V; Giordano, V; Febbraio, F; Rossi, M; Pedone, C; Manco, G
ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications
2009 M. Hilvo; G. De Simone; C.T. Supuran ;S. Parkkila
ALPHA-CARBONIC ANHYDRASES
2019 DI FIORE, Anna; D'Ambrosio, Katia; Ayoub, Joelle; Alterio, Vincenzo; DE SIMONE, Giuseppina
Amine, amino acid and oligopeptide carbonic anhydrase activators
2014 De Simone, G.; Capasso, C.; Supuran, C. T.
An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
2003 Bartolucci, Simonetta; De Simone, Giuseppina; Galdiero, Stefania; Improta, Roberto; Menchise, Valeria; Pedone, Carlo; Pedone, Emilia; Saviano, Michele
Anticancer carbonic anhydrase inhibitors: a patent review (2008-2013)
2013 Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina
Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography.
2008 Woo, Lw; Fischer, Ds; Sharland, Cm; Trusselle, M; Foster, Pa; Chander, Sk; Di Fiore, A; Supuran, Ct; De Simone, G; Purohit, A; Reed, Mj; Potter, Bv
Antiobesity carbonic anhydrase inhibitors
2007 De Simone G; Supuran CT
Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs?
2008 De Simone G; Di Fiore A; Supuran CT.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (In)organic anions as carbonic anhydrase inhibitors | 1-gen-2012 | De Simone G; Supuran CT. | |
| -RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications | 1-gen-2009 | Alterio, V; Di Fiore, A; Dambrosio, K; T Supuran, C; DE SIMONE, Giuseppina | |
| 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site | 1-gen-2020 | Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo | |
| 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity | 1-gen-2006 | M. P. Leese; B. LeBlond; S. P. Newman; A. Di Fiore; G. De Simone; C. T. Supuran; A. Purohit; M. J. Reed; B. V. L. Potter. | |
| A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases | 1-gen-2016 | Langella, Emma; D'Ambrosio, Katia; D'Ascenzio, Melissa; Carradori, Simone; Monti, Simona M.; Supuran, Claudiu T.; De Simone, Giuseppina | |
| A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors | 1-gen-2023 | Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo | |
| A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY | 1-gen-2010 | Pirone, L; Correale, S; DI GAETANO, Sonia; De Paola, I; Zaccaro, L; DE SIMONE, Giuseppina; Vitagliano, L; Pedone, C; Pedone, E | |
| A NEW LEAD COMPOUND FOR THE DEVELOPMENT OF CARBONIC ANHYDRASE INHIBITORS | 1-gen-2015 | Giuseppina De Simone; Alessandro Vergara; Marco Caterino; Vincenzo Alterio; Simona M. Monti; Joanna Ombouma; Pascal Dumy; Daniela Vullo; Claudiu T. Supuran; JeanYves Winum; Anna Di Fiore. | |
| A new role of Human Carbonic Anhydrase VII in the protection of the cells from oxidative damage | 1-gen-2013 | Monti, Dm; Del Giudice, R; Sandomenico, A; Buonanno, M; Supuran, Ct; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm | |
| A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity | 1-gen-2020 | Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella | |
| A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics. | 1-gen-2006 | D'Ambrosio, Katia; Pedone, EMILIA MARIA; Langella, Emma; DE SIMONE, Giuseppina; Rossi, Mose'; Pedone, Carlo; Bartolucci, Simonetta | |
| A substrate-induced switch in the reaction mechanism of a thermophilic esterase. Kinetic evidences and structutal basis | 1-gen-2004 | De Simone, G; Mandrich, L; Menchise, V; Giordano, V; Febbraio, F; Rossi, M; Pedone, C; Manco, G | |
| ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications | 1-gen-2009 | M. Hilvo; G. De Simone; C.T. Supuran ;S. Parkkila | |
| ALPHA-CARBONIC ANHYDRASES | 1-gen-2019 | DI FIORE, Anna; D'Ambrosio, Katia; Ayoub, Joelle; Alterio, Vincenzo; DE SIMONE, Giuseppina | |
| Amine, amino acid and oligopeptide carbonic anhydrase activators | 1-gen-2014 | De Simone, G.; Capasso, C.; Supuran, C. T. | |
| An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius | 1-gen-2003 | Bartolucci, Simonetta; De Simone, Giuseppina; Galdiero, Stefania; Improta, Roberto; Menchise, Valeria; Pedone, Carlo; Pedone, Emilia; Saviano, Michele | |
| Anticancer carbonic anhydrase inhibitors: a patent review (2008-2013) | 1-gen-2013 | Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina | |
| Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. | 1-gen-2008 | Woo, Lw; Fischer, Ds; Sharland, Cm; Trusselle, M; Foster, Pa; Chander, Sk; Di Fiore, A; Supuran, Ct; De Simone, G; Purohit, A; Reed, Mj; Potter, Bv | |
| Antiobesity carbonic anhydrase inhibitors | 1-gen-2007 | De Simone G; Supuran CT | |
| Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? | 1-gen-2008 | De Simone G; Di Fiore A; Supuran CT. |