LAEZZA, CHIARA
 Distribuzione geografica
Continente #
AS - Asia 1.899
NA - Nord America 1.067
SA - Sud America 378
EU - Europa 281
AF - Africa 44
OC - Oceania 2
Totale 3.671
Nazione #
US - Stati Uniti d'America 1.040
SG - Singapore 830
CN - Cina 461
BR - Brasile 321
HK - Hong Kong 217
VN - Vietnam 168
FR - Francia 100
KR - Corea 75
IT - Italia 69
NL - Olanda 34
JP - Giappone 32
IN - India 24
AR - Argentina 20
DE - Germania 16
GB - Regno Unito 16
IL - Israele 15
ZA - Sudafrica 15
ID - Indonesia 10
MX - Messico 10
CA - Canada 9
VE - Venezuela 9
CO - Colombia 8
EC - Ecuador 8
SA - Arabia Saudita 8
TN - Tunisia 8
UA - Ucraina 8
BD - Bangladesh 7
FI - Finlandia 7
TR - Turchia 7
UZ - Uzbekistan 7
EG - Egitto 6
IQ - Iraq 6
MA - Marocco 6
PK - Pakistan 6
AT - Austria 5
PY - Paraguay 5
RO - Romania 5
AZ - Azerbaigian 4
AE - Emirati Arabi Uniti 3
CL - Cile 3
JM - Giamaica 3
PL - Polonia 3
SE - Svezia 3
TH - Thailandia 3
TW - Taiwan 3
CZ - Repubblica Ceca 2
ES - Italia 2
GE - Georgia 2
KE - Kenya 2
KZ - Kazakistan 2
MY - Malesia 2
PE - Perù 2
RS - Serbia 2
UY - Uruguay 2
AU - Australia 1
BA - Bosnia-Erzegovina 1
BE - Belgio 1
BH - Bahrain 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CH - Svizzera 1
CI - Costa d'Avorio 1
DM - Dominica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
IE - Irlanda 1
JO - Giordania 1
KG - Kirghizistan 1
LB - Libano 1
LT - Lituania 1
MN - Mongolia 1
NG - Nigeria 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PT - Portogallo 1
RU - Federazione Russa 1
RW - Ruanda 1
TT - Trinidad e Tobago 1
Totale 3.671
Città #
Santa Clara 583
Singapore 487
Hong Kong 215
Hefei 179
Beijing 118
Lauterbourg 90
San Jose 86
Seoul 74
Ashburn 58
Ho Chi Minh City 53
Los Angeles 35
Hanoi 30
Dallas 22
São Paulo 20
Tokyo 18
New York 15
Buffalo 12
Haiphong 12
Naples 12
Minamishinagawa 11
Da Nang 10
Curitiba 9
Brasília 8
Can Tho 8
Marigliano 8
Orem 8
Rio de Janeiro 8
Bengaluru 7
Frankfurt am Main 7
Ninh Bình 7
Atlanta 6
Belo Horizonte 6
Chicago 6
Helsinki 6
Porto Alegre 6
Shanghai 6
Tashkent 6
Campinas 5
Capaci 5
Cape Town 5
Chengdu 5
Riyadh 5
Thái Bình 5
Baku 4
Boston 4
Cairo 4
Carapicuíba 4
Hải Dương 4
Johannesburg 4
Milan 4
Salvador 4
Thái Nguyên 4
Tunis 4
Wuhan 4
Asunción 3
Bauru 3
Bắc Ninh 3
Cachoeirinha 3
Casablanca 3
Cuiabá 3
Guarujá 3
Guarulhos 3
Houston 3
Jacksonville 3
Jakarta 3
Leme 3
Limeira 3
Montreal 3
Mumbai 3
Osasco 3
Porto Seguro 3
Rome 3
Sorocaba 3
Teresina 3
Warsaw 3
Amsterdam 2
Ankara 2
Baghdad 2
Bangkok 2
Barcelona 2
Belgrade 2
Belém 2
Betim 2
Birmingham 2
Biên Hòa 2
Blumenau 2
Buenos Aires 2
Bắc Giang 2
Cabo Frio 2
Campo Grande 2
Campos dos Goytacazes 2
Canoas 2
Capão da Canoa 2
Caracas 2
Colton 2
Contagem 2
Cúcuta 2
Dhaka 2
Divinópolis 2
Dubai 2
Totale 2.439
Nome #
N6-isopentenyladenosine inhibits aerobic glycolysis in glioblastoma cells by targeting PKM2 expression and activity 99
Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin. 69
Anandamide inhibits adhesion and migration of breast cancer cells. 62
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis. 59
Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice. 58
Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state. 56
Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells. 56
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells. 54
Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosis. 54
The endocannabinoid system: A target for cancer treatment 51
Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer. 51
Antiangiogenetic activity of the endocannabinoid anandamide.Correlation to its tumour-suppressor efficacy 50
N6-Isopentenyladenosine Enhances the Radiosensitivity of Glioblastoma Cells by Inhibiting the Homologous Recombination Repair Protein RAD51 Expression 50
Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets 49
N6-Isopentenyladenosine Impairs Mitochondrial Metabolism through Inhibition of EGFR Translocation on Mitochondria in Glioblastoma Cells 47
Novel role for cannabidiol in circadian clock function 46
Cannabinoids in the Modulation of Oxidative Signaling 46
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. 45
N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation. 45
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. I. Identification and characterization of a cyclic AMP-responsive element in the rat reductase promoter. 44
Advances in “adiponcosis”: Insights in the inner mechanisms at the base of adipose and tumour tissues interplay 43
Association of Alpha B-Crystallin Expression with Tumor Differentiation Grade in Colorectal Cancer Patients 40
N6-isopentenyladenosine inhibits colorectal cancer and improves sensitivity to 5-fluorouracil-targeting FBXW7 tumor suppressor 40
N6-Isopentenyladenosine Hinders the Vasculogenic Mimicry in Human Glioblastoma Cells through Src-120 Catenin Pathway Modulation and RhoA Activity Inhibition 39
Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. 39
Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris 39
Antitumoral Activity of the Universal Methyl Donor S-Adenosylmethionine in Glioblastoma Cells 38
Modified Adenosines Sensitize Glioblastoma Cells to Temozolomide by Affecting DNA Methyltransferases 38
The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice. 37
Cannabinoids and Neuro-Inflammation: Regulation of Brain Immune Response. 37
N6-isopentenyladenosine induces cell death through necroptosis in human glioblastoma cells 37
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogene. 37
Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice. 36
Cannabinoids: Therapeutic Use in Clinical Practice 36
Anandamide inhibits the Wnt/?-catenin signalling pathway in human breast cancer MDA MB 231 cells 36
Reply to the letter to the editor 34
Impacts of Environmental Pollution on Brain Tumorigenesis 34
Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells. 34
Recognition by natural killer cells of N6-isopentenyladenosine-treated human glioma cell lines 34
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. 34
Immune-Modulation and Properties of Absorption and Blood Brain Barrier Permeability of 1,8-Naphthyridine Derivatives. 34
Immuno-modulatory Properties of a Quinolin-2-(1H)-on-3-carboxamide Derivative: Relevance in Multiple Sclerosis. 33
Involvement of Akt/NF-ºB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cells. 33
Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells. 33
Cannabidiol: State of the art and new challenges for therapeutic applications 33
Molecular Mechanism of Cannabinoids in Cancer Progression 32
Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines. 32
N6-isopentenyladenosine, an endogenous isoprenoid end product, directly affects cytotoxic and regulatory functions of human NK cells through FDPS modulation. 32
Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma 32
Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. 32
Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis. 32
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway. 32
Cannabinoid receptor CB1 antagonists state of the art and challenges. 32
Immuno-modulatory and anti-inflammatory effects of dihydrogracilin a, a terpene derived from the marine sponge Dendrilla membranosa 32
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma 31
Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells. 31
N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A. 31
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 31
PPARα-Selective Antagonist GW6471 Inhibits Cell Growth in Breast Cancer Stem Cells Inducing Energy Imbalance and Metabolic Stress 31
Antiangiogenic effects of N6-isopentenyladenosine, an endogenous isoprenoid end product, mediated by AMPK activation. 31
Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer. 30
Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon 30
1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. 30
Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. 30
The Cannabinoid CB1 Receptor Antagonist Rimonabant (SR141716) Inhibits Human Breast Cancer Cell Proliferation through a Lipid Raft-Mediated Mechanism. 30
Immunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15 30
Cannabinoids and cancer: pros and cons of an antitumour strategy. 30
The N-Terminal Domain of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Harbors a GTP/ATP Binding Site. 30
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. 29
Antiglioma effects of N6-isopentenyladenosine, an endogenous isoprenoid end product, through the downregulation of epidermal growth factor receptor 29
Update on the endocannabinoid system as an anticancer target. 29
Energy metabolism in glioblastoma stem cells: PPAR? a metabolic adaptor to intratumoral microenvironment 29
Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity 29
Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration 29
Anandamide Drives Cell Cycle Progression through CB1 Receptors in a Rat Model of Synchronized Liver Regeneration. 29
Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. 28
The endocannabinoid signaling system in cancer. 28
Increased farnesyltransferase activity in human colorectal cancer: relationship with clinicopathological features and K-ras mutation 28
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. 28
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. 27
Endocannabinoids in endocrine and related tumours. 27
A new role of anandamide in human sperm: focus on metabolism. 27
N6-isopentenyladenosine affects cytotoxic activity and cytokines production by IL-2 activated NK cells and exerts topical anti-inflammatory activity in mice 27
Statins in neurological disorders: An overview and update 27
PPAR? Antagonist AA452 Triggers Metabolic Reprogramming and Increases Sensitivity to Radiation Therapy in Human Glioblastoma Primary Cells 26
Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis 26
N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux 26
p53 regulates the mevalonate pathway in human glioblastoma multiforme. 25
Association between Cannabinoid type-1 receptor polymorphism and body mass index in a Southern Italian population. 25
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells 25
Human Sperm Anatomy: Ultrastructural Localization of the Cannabinoid1 Receptor and a Potential Role of Anandamide in Sperm Survival and Acrosome Reaction. 25
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. 24
Endocannabionoid System in Neurological Disorders. 24
The anandamide analogue, Met-F-AEA, controls human breast cancer cell migration via the RhoA/Rho kinase signaling pathway. 24
Inhibitory effects of cannabinoid CB 1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis. 24
HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway 23
Arvanil inhibits T-lynphocyte activation and ameliorates the course and progression of experimental autoimmune encephalomyelitis 22
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation 22
Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines. 21
Endocannabinoids as emergine suppressors of angiogenesis and tumor invasion 21
Totale 3.546
Categoria #
all - tutte 11.827
article - articoli 11.366
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.193


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202413 0 0 0 0 0 0 0 0 3 0 8 2
2024/20251.642 6 5 87 59 503 90 33 109 55 31 334 330
2025/20262.099 128 270 212 350 370 57 329 121 138 78 43 3
Totale 3.754