CARLOMAGNO, FRANCESCA
CARLOMAGNO, FRANCESCA
Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia "G. Salvatore" (IEOMI)
D898_E901 RET Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms
2023 Porcelli, Tommaso; Moccia, Marialuisa; De Stefano, Maria Angela; Ambrosio, Raffaele; Capoluongo, Ettore; Santoro, Massimo; Hadoux, Julien; Schlumberger, Martin; Carlomagno, Francesca; Salvatore, Domenico
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose
2022 Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C.; Bharate, Jaideep B.; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q.; Carlomagno, Francesca; Li, Hong-yu
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation
2021 Yan, Wei; Zhang, Lingtian; Lv, Fengping; Moccia, Marialuisa; Carlomagno, Francesca; Landry, Christophe; Santoro, Massimo; Gosselet, Fabien; Frett, Brendan; Li, Hong-yu
Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases
2021 Moccia, Marialuisa; Yang, Donglin; Lakkaniga, Naga Rajiv; Frett, Brendan; Mcconnell, Nicholas; Zhang, Lingtian; Brescia, Annalisa; Federico, Giorgia; Zhang, Lingzhi; Salerno, Paolo; Santoro, Massimo; Li, Hong-yu; Carlomagno, Francesca
Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology
2020 Moccia, M; Frett, B; Zhang, L; Lakkaniga, Nr; Briggs, Dc; Chauhan, R; Brescia, A; Federico, G; Yan, W; Santoro, M; Mcdonald, Nq; Li, Hy; Carlomagno, F
NCOA4-mediated Ferritinophagy in Macrophages Is Crucial to Sustain Erythropoiesis in Mice
2020 Nai, Antonella; Rosa Lidonnici, Maria; Federico, Giorgia; Pettinato, Mariateresa; Olivari, Violante; Carrillo, Federica; Geninatti Crich, Simonetta; Ferrari, Giuliana; Camaschella, Clara; Silvestri, Laura; Carlomagno, Francesca
Ret gene fusions in malignancies of the thyroid and other tissues
2020 Santoro, M; Moccia, M; Federico, G; Carlomagno, F
Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms
2019 Affinito, Ornella; Salerno, Paolo; D'Alessio, Alfonso; Cuomo, Mariella; Florio, Ermanno; Carlomagno, Francesca; Proietti, Agnese; Giannini, Riccardo; Basolo, Fulvio; Chiariotti, Lorenzo; Cocozza, Sergio; Santoro, Massimo
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application
2019 Yan W.; Lakkaniga N.R.; Carlomagno F.; Santoro M.; McDonald N.Q.; Lv F.; Gunaganti N.; Frett B.; Li H.Y.
Iron and ferritin modulate MHC Class i expression and NK cell recognition
2019 Sottile R.; Federico G.; Garofalo C.; Tallerico R.; Faniello M.C.; Quaresima B.; Cristiani C.M.; Di Sanzo M.; Cuda G.; Ventura V.; Wagner A.K.; Contro G.; Perrotti N.; Gulletta E.; Ferrone S.; Karre K.; Costanzo F.S.; Carlomagno F.; Carbone E.
Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis
2019 Nai A.; Pettinato M.; Federico G.; Olivari V.; Carlomagno F.; Silvestri L.
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis
2018 Matte, A; De Falco, L; Federti, E; Cozzi, A; Iolascon, A; Levi, S; Mohandas, N; Zamo, A; Bruno, M; Lebouef, C; Janin, A; Siciliano, A; Ganz, T; Federico, G; Carlomagno, F; Mueller, S; Silva, I; Carbone, C; Melisi, D; Kim, Dw; Choi, Sy; De Franceschi, L
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer
2017 De Falco V.; Carlomagno F.; Li H.Y.; Santoro M.
NCOA4 deficiency impairs systemic iron homeostasis
2016 Bellelli, R; Federico, G; Mattè, A; Colecchia, D; Iolascon, A; Chiariello, M; Santoro, M; De Franceschi, L; Carlomagno, F
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology
2015 Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu
Identification of novel small molecule inhibitors of oncogenic RET kinase
2015 Moccia, M; Liu, Q; Guida, T; Federico, G; Brescia, A; Zhao, Z; Choi, Hg; Deng, X; Tan, L; Wang, J; Billaud, M; Gray, Ns; Carlomagno, F; Santoro, M
Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies
2014 Bossi D.; Carlomagno F.; Pallavicini I.; Pruneri G.; Trubia M.; Raviele P.R.; Marinelli A.; Anaganti S.; Cox M.C.; Viale G.; Santoro M.; Di Fiore P.P.; Minucci S.
Growth factor transduction pathways: Paradigm of anti-neoplastic targeted therapy
2014 Carlomagno F.; Chiariello M.
Identification of two novel RET kinase inhibitors through MCR-based drug discovery: Design, synthesis and evaluation
2014 Frett, B; Moccia, M; Carlomagno, F; Santoro, M; Li, Hy
Attacking cancer with molecularly targeted agents Editorial overview
2013 Santoro, M; Carlomagno, F
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
D898_E901 RET Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms | 1-gen-2023 | Porcelli, Tommaso; Moccia, Marialuisa; De Stefano, Maria Angela; Ambrosio, Raffaele; Capoluongo, Ettore; Santoro, Massimo; Hadoux, Julien; Schlumberger, Martin; Carlomagno, Francesca; Salvatore, Domenico | |
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose | 1-gen-2022 | Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C.; Bharate, Jaideep B.; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q.; Carlomagno, Francesca; Li, Hong-yu | |
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation | 1-gen-2021 | Yan, Wei; Zhang, Lingtian; Lv, Fengping; Moccia, Marialuisa; Carlomagno, Francesca; Landry, Christophe; Santoro, Massimo; Gosselet, Fabien; Frett, Brendan; Li, Hong-yu | |
Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases | 1-gen-2021 | Moccia, Marialuisa; Yang, Donglin; Lakkaniga, Naga Rajiv; Frett, Brendan; Mcconnell, Nicholas; Zhang, Lingtian; Brescia, Annalisa; Federico, Giorgia; Zhang, Lingzhi; Salerno, Paolo; Santoro, Massimo; Li, Hong-yu; Carlomagno, Francesca | |
Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology | 1-gen-2020 | Moccia, M; Frett, B; Zhang, L; Lakkaniga, Nr; Briggs, Dc; Chauhan, R; Brescia, A; Federico, G; Yan, W; Santoro, M; Mcdonald, Nq; Li, Hy; Carlomagno, F | |
NCOA4-mediated Ferritinophagy in Macrophages Is Crucial to Sustain Erythropoiesis in Mice | 1-gen-2020 | Nai, Antonella; Rosa Lidonnici, Maria; Federico, Giorgia; Pettinato, Mariateresa; Olivari, Violante; Carrillo, Federica; Geninatti Crich, Simonetta; Ferrari, Giuliana; Camaschella, Clara; Silvestri, Laura; Carlomagno, Francesca | |
Ret gene fusions in malignancies of the thyroid and other tissues | 1-gen-2020 | Santoro, M; Moccia, M; Federico, G; Carlomagno, F | |
Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms | 1-gen-2019 | Affinito, Ornella; Salerno, Paolo; D'Alessio, Alfonso; Cuomo, Mariella; Florio, Ermanno; Carlomagno, Francesca; Proietti, Agnese; Giannini, Riccardo; Basolo, Fulvio; Chiariotti, Lorenzo; Cocozza, Sergio; Santoro, Massimo | |
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application | 1-gen-2019 | Yan W.; Lakkaniga N.R.; Carlomagno F.; Santoro M.; McDonald N.Q.; Lv F.; Gunaganti N.; Frett B.; Li H.Y. | |
Iron and ferritin modulate MHC Class i expression and NK cell recognition | 1-gen-2019 | Sottile R.; Federico G.; Garofalo C.; Tallerico R.; Faniello M.C.; Quaresima B.; Cristiani C.M.; Di Sanzo M.; Cuda G.; Ventura V.; Wagner A.K.; Contro G.; Perrotti N.; Gulletta E.; Ferrone S.; Karre K.; Costanzo F.S.; Carlomagno F.; Carbone E. | |
Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis | 1-gen-2019 | Nai A.; Pettinato M.; Federico G.; Olivari V.; Carlomagno F.; Silvestri L. | |
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis | 1-gen-2018 | Matte, A; De Falco, L; Federti, E; Cozzi, A; Iolascon, A; Levi, S; Mohandas, N; Zamo, A; Bruno, M; Lebouef, C; Janin, A; Siciliano, A; Ganz, T; Federico, G; Carlomagno, F; Mueller, S; Silva, I; Carbone, C; Melisi, D; Kim, Dw; Choi, Sy; De Franceschi, L | |
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer | 1-gen-2017 | De Falco V.; Carlomagno F.; Li H.Y.; Santoro M. | |
NCOA4 deficiency impairs systemic iron homeostasis | 1-gen-2016 | Bellelli, R; Federico, G; Mattè, A; Colecchia, D; Iolascon, A; Chiariello, M; Santoro, M; De Franceschi, L; Carlomagno, F | |
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology | 1-gen-2015 | Frett, Brendan; Carlomagno, Francesca; Moccia Maria, Luisa; Brescia, Annalisa; Federico, Giorgia; DE FALCO, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hongyu | |
Identification of novel small molecule inhibitors of oncogenic RET kinase | 1-gen-2015 | Moccia, M; Liu, Q; Guida, T; Federico, G; Brescia, A; Zhao, Z; Choi, Hg; Deng, X; Tan, L; Wang, J; Billaud, M; Gray, Ns; Carlomagno, F; Santoro, M | |
Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies | 1-gen-2014 | Bossi D.; Carlomagno F.; Pallavicini I.; Pruneri G.; Trubia M.; Raviele P.R.; Marinelli A.; Anaganti S.; Cox M.C.; Viale G.; Santoro M.; Di Fiore P.P.; Minucci S. | |
Growth factor transduction pathways: Paradigm of anti-neoplastic targeted therapy | 1-gen-2014 | Carlomagno F.; Chiariello M. | |
Identification of two novel RET kinase inhibitors through MCR-based drug discovery: Design, synthesis and evaluation | 1-gen-2014 | Frett, B; Moccia, M; Carlomagno, F; Santoro, M; Li, Hy | |
Attacking cancer with molecularly targeted agents Editorial overview | 1-gen-2013 | Santoro, M; Carlomagno, F |