VACCA, ROSA ANNA
 Distribuzione geografica
Continente #
AS - Asia 1.823
NA - Nord America 1.119
EU - Europa 534
SA - Sud America 298
AF - Africa 39
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.818
Nazione #
US - Stati Uniti d'America 1.058
SG - Singapore 762
CN - Cina 452
BR - Brasile 240
IT - Italia 201
VN - Vietnam 173
HK - Hong Kong 169
FR - Francia 120
KR - Corea 70
JP - Giappone 61
NL - Olanda 43
GB - Regno Unito 36
IN - India 34
DE - Germania 31
BD - Bangladesh 26
CA - Canada 26
FI - Finlandia 26
MX - Messico 21
AR - Argentina 16
ID - Indonesia 16
EC - Ecuador 14
ZA - Sudafrica 13
IL - Israele 10
PL - Polonia 9
ES - Italia 8
IQ - Iraq 8
TR - Turchia 8
SE - Svezia 7
AE - Emirati Arabi Uniti 6
AT - Austria 6
CO - Colombia 6
RU - Federazione Russa 6
UA - Ucraina 6
VE - Venezuela 6
AL - Albania 5
CL - Cile 5
HU - Ungheria 5
JM - Giamaica 5
MA - Marocco 5
UZ - Uzbekistan 5
KE - Kenya 4
LV - Lettonia 4
NP - Nepal 4
PY - Paraguay 4
CZ - Repubblica Ceca 3
PE - Perù 3
PK - Pakistan 3
PT - Portogallo 3
SA - Arabia Saudita 3
TT - Trinidad e Tobago 3
AU - Australia 2
AZ - Azerbaigian 2
BF - Burkina Faso 2
BO - Bolivia 2
BS - Bahamas 2
CH - Svizzera 2
CM - Camerun 2
EG - Egitto 2
GR - Grecia 2
IE - Irlanda 2
JO - Giordania 2
KZ - Kazakistan 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
PH - Filippine 2
RO - Romania 2
TH - Thailandia 2
UY - Uruguay 2
AO - Angola 1
BE - Belgio 1
BG - Bulgaria 1
BH - Bahrain 1
BW - Botswana 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GH - Ghana 1
HN - Honduras 1
HR - Croazia 1
LB - Libano 1
LT - Lituania 1
MG - Madagascar 1
MZ - Mozambico 1
PS - Palestinian Territory 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
TC - Turks e Caicos 1
TN - Tunisia 1
TZ - Tanzania 1
UG - Uganda 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 3.818
Città #
Singapore 442
Santa Clara 396
Hefei 186
San Jose 170
Hong Kong 168
Beijing 113
Ashburn 92
Lauterbourg 80
Seoul 70
Ho Chi Minh City 56
Tokyo 53
Dallas 38
Bari 35
Hanoi 34
Los Angeles 30
São Paulo 24
Frankfurt am Main 19
Milan 18
New York 18
Helsinki 15
Rome 15
Buffalo 13
Orem 13
Haiphong 11
Potenza 10
Lappeenranta 9
Naples 9
Phoenix 9
Toronto 9
Bengaluru 8
Council Bluffs 8
Minamishinagawa 8
Chennai 7
Genoa 7
Johannesburg 7
Stockholm 7
Boston 6
Brasília 6
Juiz de Fora 6
Messina 6
Portsmouth 6
Warsaw 6
Biên Hòa 5
Bắc Ninh 5
Campinas 5
Da Nang 5
Guayaquil 5
Gustavo Adolfo Madero 5
Houston 5
Livorno 5
London 5
Rio de Janeiro 5
Shanghai 5
Amsterdam 4
Atlanta 4
Baghdad 4
Brooklyn 4
Denver 4
Düsseldorf 4
Fortaleza 4
Goiânia 4
Guangzhou 4
Kingston 4
Miami 4
Nairobi 4
Palermo 4
Phủ Lý 4
Poplar 4
Quito 4
Riga 4
Santiago 4
Tashkent 4
Ankara 3
Asunción 3
Belo Horizonte 3
Betim 3
Bologna 3
Can Tho 3
Catania 3
City of London 3
Dhaka 3
Dubai 3
Ha Long 3
Hyderabad 3
Lima 3
Louisville 3
Madrid 3
Marigliano 3
Mexico City 3
Montreal 3
Munich 3
Ninh Bình 3
Nuremberg 3
Porto Alegre 3
Pune 3
Quận Một 3
San Francisco 3
Vigodarzere 3
Wroclaw 3
Amman 2
Totale 2.457
Nome #
Serious Games in the new era of digital-health interventions: A narrative review of their therapeutic applications to manage neurobehavior in neurodevelopmental disorders 121
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis 102
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through# INPST hashtag analysis 90
The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model 89
Mitochondrial alterations in a mouse model of Fragile X syndrome 83
Autism spectrum disorder from the womb to adulthood: Suggestions for a paradigm shift 81
Pharmacological inhibition of the CB1 cannabinoid receptor restores abnormal brain mitochondrial CB1 receptor expression and rescues bioenergetic and cognitive defects in a female mouse model of Rett syndrome 78
Serious Games as Emerging E-Health Interventions: Design of an Exergame for the SMILER Project 77
Natural products in drug discovery: advances and opportunities 77
Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome 75
Aberrant mitochondrial bioenergetics in the cerebral cortex of the Fmr1 knockout mouse model of fragile X syndrome 73
Targeting Epigenetics in Cancer: Therapeutic Potential of Flavonoids 73
A transient proteasome activation is needed for acetic acid-induce programmed cell death to occur in Saccharomyces cerevisiae 71
Role of Nitric Oxide in Neurodegeneration: Function, Regulation and Inhibition 70
Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F0F1-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy 66
β1C Integrin Expression in Human Endometrial Proliferative Diseases 65
Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention 64
Brain Mitochondrial Bioenergetics in Genetic Neurodevelopmental Disorders: Focus on Down, Rett and Fragile X Syndromes 62
Natural products, PGC-1alpha, and Duchenne muscular dystrophy 61
Treatment with the Bacterial Toxin CNF1 Selectively Rescues Cognitive and Brain Mitochondrial Deficits in a Female Mouse Model of Rett Syndrome Carrying a MeCP2-Null Mutation 60
Primary and Secondary Mitochondrial Diseases: Etiologies and Therapeutic Strategies 54
Mitochondria can cross cell boundaries: An overview of the biological relevance, pathophysiological implications and therapeutic perspectives of intercellular mitochondrial transfer 52
The Underestimated Role of the p53 Pathway in Renal Cancer 51
Impaired brain mitochondrial bioenergetics in the ts65dn mouse model of down syndrome is restored by neonatal treatment with the polyphenol 7,8-dihydroxyflavone 49
Erratum: Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity (Eur. J. Biochem. Vol. 227, No. 1/2) 48
Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder 46
Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma. 45
Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco Bright-Yellow 2 cells. 44
Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome 44
The Anti-Diabetic Drug Metformin Rescues Aberrant Mitochondrial Activity and Restrains Oxidative Stress in a Female Mouse Model of Rett Syndrome 44
3-Bromopyruvate induces rapid human prostate cancer cell death by affecting cell energy metabolism, GSH pool and the glyoxalase system 43
Alternatively Spliced Variants of B1 Integrin Are Involved in the Modulation of Human Endometrial Transformation in Different Physiological/Pathological conditions 42
Helium-Neon laser irradiation of hepatocytes can trigger increase of the mitochondrial membrane potential and can stimulate c-fos expression in a Ca2+-dependent manner 42
Multifactorial Impairment of mitochondrial oxidative phosphorylation in human skin fibroblasts with chromosome 21 trisomy 41
Polydatin and its potential protective effect on COVID-19 41
Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model 41
Thyroid hormone administration to hypothyroid rats restores the mitochondrial membrane permeability properties 40
Impairment of ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy 39
b1C integrin expression in human endometrial proliferative diseases. 39
Molecular basis of cystic fibrosis in Lithuania. Incomplete CFTR mutation detection by PCR-based screening protocols 39
Mitochondria as pharmacological targets in Down syndrome 39
Targeting STATs in neuroinflammation: The road less traveled! 38
Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: Protective effect of CNF1 38
Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy 38
Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells 38
Alternatively Spliced Variants of Beta1 Integrin Are Involved in the Modulation of Human Endometrial Transformation in Different Physiological/Pathological Conditions 38
Hypothyroidism affects mitochondrial functions in rat liver 37
Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas 37
ROLE OF MITOCHONDRIAL DYSFUNCTIONS IN DOWN SYNDROME PATHOGENESIS: NEW MOLECULAR TARGETS AND THERAPEUTIC STRATEGIES 37
Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway 36
Brain-Immune Alterations and Mitochondrial Dysfunctions in a Mouse Model of Paediatric Autoimmune Disorder Associated with Streptococcus: Exacerbation by Chronic Psychosocial Stress 36
Increase in cytosolic and mitochondrial protein synthesis in rat hepatocytes irradiated in vitro by He-Ne laser 35
Cytochrome c Is Released in a Reactive Oxygen Species-Dependent Manner and Is Degraded via Caspase-Like Proteases in Tobacco Bright-Yellow 2 Cells en Route to Heat Shock-Induced Cell Death. 35
Integrin B1C role in the human proliferative disease. 34
Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome 33
Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders 32
Green tea EGCG plus fish oil omega-3 dietary supplements rescue mitochondrial dysfunctions and are safe in a Down's syndrome child 32
Active-site Arg --> Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase. 31
Novel therapeutic strategies for stroke: The role of autophagy 30
Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome 30
B-1C integrin expression is regulated in human proliferative diseases 30
Modulation of Rho GTPases rescues brain mitochondrial dysfunction and cognitive deficits in a mouse model of Rett syndrome 30
The irradiation of hepatocytes with He-Ne laser causes an increase of cytosolic free calcium concentration and an increase of cell membrane potential, correlated with it, both increases taking place in an oscillatory manner 30
Plasma and urinary metabolomic profiles of Down syndrome correlate with alteration of mitochondrial metabolism. 29
A transient proteasome activation is needed for acetic acid-induced programmed cell death to occur in Saccharomyces cerevisiae. 29
Down syndrome: Neurobiological alterations and therapeutic targets 29
In the early phase of programmed cell death in Tobacco Bright Yellow 2 cells the mitochondrial adenine nucleotide translocator, adenylate kinase and nucleoside diphosphate kinase are impaired in a reactive oxygen species-dependent manner. 29
Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome 29
Perspectives of protein engineering in the study of molecular basis of human inherited diseases. 29
Targeting ubiquitin-proteasome pathway by natural, in particular polyphenols, anticancer agents: Lessons learned from clinical trials 28
Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome 28
Mitochondrial Bioenergetics in Human skin fibroblasts with chromosome 21 trisomy: deficiency in complex I and production of mitochondrial ATP and increase in mitochondrial mass, reactive oxygen species and production of lactate 28
Unbalance of the ascorbate and glutathione redox state and downregulation of the cytosolic ascorbate peroxidase are early events in the programmed cell death induced by heat shock in tobacco BY-2 cells 27
Therapeutic role of sirtuins in neurodegenerative disease and their modulation by polyphenols 27
Import of mutant forms of mitochondrial aspartate aminotransferase into isolated mitochondria 27
Comparison of the efficacy of gesture-verbal treatment and doll therapy for managing neuropsychiatric symptoms in older patients with dementia 27
IMPAIRMENT OF OXIDATIVE PHOSPHORYLATION APPARATUS AND OVERPRODUCTION OF RADICAL SPECIES BY MITOCHONDRIA IN DOWN SYNDROME 26
Molecular targets and role of mitochondria dysfunction in Down syndrome pathogenesis 26
Helium-Neon laser irradiation of hepatocytes can trigger increase of the mitochondrial membrane potential and can stimulate c-fos expression in a Ca2+-dependent manner 26
Correlation among the biochemical events that occur in isolated hepatocytes after Helium-Neon laser irradiatio 25
Estrogen receptor beta activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo. 25
The molecular evolution of B6 enzymes: ribonuclease A as a model pyridoxal-5 -phosphate-dependent protoenzyme. 25
Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration 23
Increase of both transcription and translation activities following separate irradiation of the in vitro system components with He-Ne laser 23
Regulation of mRNA and protein levels of beta 1 integrin variants in human prostate carcinoma 23
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. 23
Polydatin reactivates mitochondrial bioenergetics and mitophagy while preventing premature senescence by modulating microRNA-155 and its direct targets in human fibroblasts with trisomy 21 23
Plant polyphenols as natural drugs for the management of Down syndrome and related disorders. 23
Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity 22
Le applicazioni terapeutiche della molecola del tè verde 22
Differential expression of b1C integrin messenger ribonucleic acid and protein levels in human endometrium and decidua during the menstrual cycle and pregnancy. 22
Helium-Neon laser activation of mitochondrial biogenesis 22
Activation of mitochondrial DNA replication by He-Ne laser irradiation 21
Dalla natura una speranza per le persone down 21
Effect of He-Ne Laser irradiation on DNA replication and transcription and protein synthesis. 20
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells 18
Totale 4.041
Categoria #
all - tutte 13.268
article - articoli 11.745
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 621
Totale 25.634


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202416 0 0 0 0 0 0 0 0 2 1 10 3
2024/20251.775 2 4 119 54 408 68 44 287 53 103 327 306
2025/20262.250 123 257 157 348 429 97 279 162 133 165 100 0
Totale 4.041