PAPPALARDO, GIUSEPPE
PAPPALARDO, GIUSEPPE
Istituto di Cristallografia - IC - Sede Secondaria Catania
Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life
2025 Latina, Valentina; De Introna, Margherita; Malerba, Francesca; Florio, Rita; Balzamino, Bijorn Omar; Di Natale, Giuseppe; Sciacca, Michele Francesco Maria; Pappalardo, Giuseppe; Micera, Alessandra; Pignataro, Annabella; Calissano, Pietro; Amadoro, Giuseppina
Bioinspired RGD-Functionalized Gold Nanoparticles for Integrin-Driven Interaction with Melanoma Cells
2025 Del Gatto, A.; Di Pietro, P.; Saviano, M.; Tomasello, M. F.; Pappalardo, G.; Snyders, R.; Forte, G.; Satriano, C.; Zaccaro, L.
Functionalizing cryogels with the GPGKLVFF peptide for amyloid-β binding: A comparative study of two synthetic pathways
2025 Hu, Kaiyue; Mecca, Tommaso; Sabatino, Giuseppina; Satriano, Cristina; Brambilla, Luigi; Dattilo, Sandro; Giglio, Valentina; Di Natale, Giuseppe; Castiglioni, Chiara; Cunsolo, Francesca; Pappalardo, Giuseppe
KLVFF Functionalized Graphene Oxide for Aβ42 Peptide Electrical Detection: A Promising Nanomaterial for the Development of Alzheimer's Disease Diagnostic Devices
2025 Scuderi, Viviana; Turnaturi, Rita; Filice, Simona; Crispi, Simona; Natale, Giuseppe Di; Sabatino, Giuseppina; Ricciarelli, Damiano; Fisicaro, Giuseppe; Pappalardo, Giuseppe; La Magna, Antonino; Scalese, Silvia
Memantine and amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice
2025 Bocchieri, Eleonora; Zimbone, Stefania; Giuffrida, Maria Laura; Di Natale, Giuseppe; Sabatino, Giuseppina; Vecchio, Graziella; Pappalardo, Giuseppe; Chiechio, Santina
The hydrolytic stability of the human tubulin α 1A protein fragment – a potential reason for the role of metal ions in the development of neurodegenerative diseases
2025 Sándor, Balázs; Grenács, Ágnes; Sajtos, Gergő Zoltán; Sabatino, Giuseppina; Di Natale, Giuseppe; Pappalardo, Giuseppe; Várnagy, Katalin
A Spectroscopic Study on the Amyloid‐β Interaction with Clicked Peptide‐Porphyrin Conjugates: a Vision Toward the Detection of Aβ Peptides in Aqueous Solution
2024 Tosto, Rita; Zimbone, Stefania; Sabatino, Giuseppina; Di Natale, Giuseppe; Laura Giuffrida, Maria; Flora Tomasello, Marianna; Lanzanò, Luca; Campagna, Tiziana; Covaceuszach, Sonia; Vecchio, Graziella; Pappalardo, Giuseppe
A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction
2024 Tosto, Rita; Zimbone, Stefania; Di Natale, Giuseppe; Giuffrida, Maria Laura; Campagna, Tiziana; Pappalardo, Giuseppe; Sabatino, Giuseppina
Functional modification of graphene nanoparticles: covalent grafting of peptides and π bonding for drug loading and delivery
2024 Hu, Kaiyue; Brambilla, Luigi; Moretti, Paola; Bertarelli, Chiara; Castiglioni, Chiara; Pappalardo, Giuseppe; Sabatino, Giuseppina
New Conjugates of Hyaluronic Acid with γ-Cyclodextrin as Sorafenib Carrier in Cancer Cells
2024 Bognanni, N.; Viale, M.; Sabatino, G.; Pappalardo, G.; Vecchio, G.
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment
2023 Zimbone, S.; Giuffrida, M. L.; Sabatino, G.; Di Natale, G.; Tosto, R.; Consoli, G. M. L.; Milardi, D.; Pappalardo, G.; Sciacca, M. F. M.
The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment
2023 Zimbone, Stefania; Giuffrida, MARIA LAURA; Sabatino, Giuseppina; DI NATALE, Giuseppe; Tosto, Rita; Consoli, Grazia M. L.; Milardi, Danilo; Pappalardo, Giuseppe; Sciacca, Michele F. M.
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease?
2022 DI NATALE, Giuseppe; Sabatino, Giuseppina; Sciacca, MICHELE FRANCESCO MARIA; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe
KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing
2022 Mazzaglia, Antonino; DI NATALE, Giuseppe; Tosto, Rita; Scala, Angela; Sortino, Giuseppe; Piperno, Anna; Casaletto, MARIA PIA; Riminucci, Alberto; Giuffrida, MARIA LAURA; Mineo Placido, G; Villari, Valentina; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe
Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study
2021 Balogh, Bd; Szakacs, B; Di Natale, G; Tabbi, G; Pappalardo, G; Sovago, I; Varnagy, K
Cyclodextrin Polymers as Delivery Systems for Targeted Anti-Cancer Chemoth
2021 Bognanni Maurizio Viale, Noemi; Distefano, Alessia; Tosto, Rita; Bertola, Nadia; Loiacono, Fabrizio; Ponassi, Marco; Spinelli, Domenico; Pappalardo, Giuseppe; Vecchio, Graziella
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro
2021 Consoli, GRAZIA MARIA LETIZIA; Tosto, R.; Baglieri, A.; Petralia, S.; Campagna, T.; DI NATALE, Giuseppe; Zimbone, S.; Giuffrida, M. L.; Pappalardo, Giuseppe.
Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles
2021 Sciacca, MICHELE FRANCESCO MARIA; Di Natale, G; Milardi, D; Pappalardo, G
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence
2020 Sciacca, Michele Francesco Maria; Di Natale, Giuseppe; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe
Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study
2019 Lukacs M.; Szunyog G.; Grenacs A.; Lihi N.; Kallay C.; Di Natale G.; Campagna T.; Lanza V.; Tabbi G.; Pappalardo G.; Sovago I.; Varnagy K.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life | 1-gen-2025 | Latina, Valentina; De Introna, Margherita; Malerba, Francesca; Florio, Rita; Balzamino, Bijorn Omar; Di Natale, Giuseppe; Sciacca, Michele Francesco Maria; Pappalardo, Giuseppe; Micera, Alessandra; Pignataro, Annabella; Calissano, Pietro; Amadoro, Giuseppina | |
| Bioinspired RGD-Functionalized Gold Nanoparticles for Integrin-Driven Interaction with Melanoma Cells | 1-gen-2025 | Del Gatto, A.; Di Pietro, P.; Saviano, M.; Tomasello, M. F.; Pappalardo, G.; Snyders, R.; Forte, G.; Satriano, C.; Zaccaro, L. | |
| Functionalizing cryogels with the GPGKLVFF peptide for amyloid-β binding: A comparative study of two synthetic pathways | 1-gen-2025 | Hu, Kaiyue; Mecca, Tommaso; Sabatino, Giuseppina; Satriano, Cristina; Brambilla, Luigi; Dattilo, Sandro; Giglio, Valentina; Di Natale, Giuseppe; Castiglioni, Chiara; Cunsolo, Francesca; Pappalardo, Giuseppe | |
| KLVFF Functionalized Graphene Oxide for Aβ42 Peptide Electrical Detection: A Promising Nanomaterial for the Development of Alzheimer's Disease Diagnostic Devices | 1-gen-2025 | Scuderi, Viviana; Turnaturi, Rita; Filice, Simona; Crispi, Simona; Natale, Giuseppe Di; Sabatino, Giuseppina; Ricciarelli, Damiano; Fisicaro, Giuseppe; Pappalardo, Giuseppe; La Magna, Antonino; Scalese, Silvia | |
| Memantine and amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice | 1-gen-2025 | Bocchieri, Eleonora; Zimbone, Stefania; Giuffrida, Maria Laura; Di Natale, Giuseppe; Sabatino, Giuseppina; Vecchio, Graziella; Pappalardo, Giuseppe; Chiechio, Santina | |
| The hydrolytic stability of the human tubulin α 1A protein fragment – a potential reason for the role of metal ions in the development of neurodegenerative diseases | 1-gen-2025 | Sándor, Balázs; Grenács, Ágnes; Sajtos, Gergő Zoltán; Sabatino, Giuseppina; Di Natale, Giuseppe; Pappalardo, Giuseppe; Várnagy, Katalin | |
| A Spectroscopic Study on the Amyloid‐β Interaction with Clicked Peptide‐Porphyrin Conjugates: a Vision Toward the Detection of Aβ Peptides in Aqueous Solution | 1-gen-2024 | Tosto, Rita; Zimbone, Stefania; Sabatino, Giuseppina; Di Natale, Giuseppe; Laura Giuffrida, Maria; Flora Tomasello, Marianna; Lanzanò, Luca; Campagna, Tiziana; Covaceuszach, Sonia; Vecchio, Graziella; Pappalardo, Giuseppe | |
| A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction | 1-gen-2024 | Tosto, Rita; Zimbone, Stefania; Di Natale, Giuseppe; Giuffrida, Maria Laura; Campagna, Tiziana; Pappalardo, Giuseppe; Sabatino, Giuseppina | |
| Functional modification of graphene nanoparticles: covalent grafting of peptides and π bonding for drug loading and delivery | 1-gen-2024 | Hu, Kaiyue; Brambilla, Luigi; Moretti, Paola; Bertarelli, Chiara; Castiglioni, Chiara; Pappalardo, Giuseppe; Sabatino, Giuseppina | |
| New Conjugates of Hyaluronic Acid with γ-Cyclodextrin as Sorafenib Carrier in Cancer Cells | 1-gen-2024 | Bognanni, N.; Viale, M.; Sabatino, G.; Pappalardo, G.; Vecchio, G. | |
| Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment | 1-gen-2023 | Zimbone, S.; Giuffrida, M. L.; Sabatino, G.; Di Natale, G.; Tosto, R.; Consoli, G. M. L.; Milardi, D.; Pappalardo, G.; Sciacca, M. F. M. | |
| The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment | 1-gen-2023 | Zimbone, Stefania; Giuffrida, MARIA LAURA; Sabatino, Giuseppina; DI NATALE, Giuseppe; Tosto, Rita; Consoli, Grazia M. L.; Milardi, Danilo; Pappalardo, Giuseppe; Sciacca, Michele F. M. | |
| A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? | 1-gen-2022 | DI NATALE, Giuseppe; Sabatino, Giuseppina; Sciacca, MICHELE FRANCESCO MARIA; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe | |
| KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing | 1-gen-2022 | Mazzaglia, Antonino; DI NATALE, Giuseppe; Tosto, Rita; Scala, Angela; Sortino, Giuseppe; Piperno, Anna; Casaletto, MARIA PIA; Riminucci, Alberto; Giuffrida, MARIA LAURA; Mineo Placido, G; Villari, Valentina; Micali, NORBERTO LIBORIO; Pappalardo, Giuseppe | |
| Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study | 1-gen-2021 | Balogh, Bd; Szakacs, B; Di Natale, G; Tabbi, G; Pappalardo, G; Sovago, I; Varnagy, K | |
| Cyclodextrin Polymers as Delivery Systems for Targeted Anti-Cancer Chemoth | 1-gen-2021 | Bognanni Maurizio Viale, Noemi; Distefano, Alessia; Tosto, Rita; Bertola, Nadia; Loiacono, Fabrizio; Ponassi, Marco; Spinelli, Domenico; Pappalardo, Giuseppe; Vecchio, Graziella | |
| Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro | 1-gen-2021 | Consoli, GRAZIA MARIA LETIZIA; Tosto, R.; Baglieri, A.; Petralia, S.; Campagna, T.; DI NATALE, Giuseppe; Zimbone, S.; Giuffrida, M. L.; Pappalardo, Giuseppe. | |
| Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles | 1-gen-2021 | Sciacca, MICHELE FRANCESCO MARIA; Di Natale, G; Milardi, D; Pappalardo, G | |
| Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence | 1-gen-2020 | Sciacca, Michele Francesco Maria; Di Natale, Giuseppe; Tosto, Rita; Milardi, Danilo; Pappalardo, Giuseppe | |
| Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study | 1-gen-2019 | Lukacs M.; Szunyog G.; Grenacs A.; Lihi N.; Kallay C.; Di Natale G.; Campagna T.; Lanza V.; Tabbi G.; Pappalardo G.; Sovago I.; Varnagy K. |