MAGA, GIOVANNI
MAGA, GIOVANNI
Dipartimento di Scienze Biomediche - DSB
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections
2024 Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco
Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma
2024 Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia
Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
2024 Boufaied, Nadia; Chetta, Paolo; Hallal, Tarek; Cacciatore, Stefano; Lalli, Daniela; Luthold, Carole; Homsy, Kevin; Imada, Eddie L.; Syamala, Sudeepa; Photopoulos, Cornelia; Di Matteo, Anna; de Polo, Anna; Storaci, Alessandra Maria; Huang, Ying; Giunchi, Francesca; Sheridan, Patricia A.; Michelotti, Gregory; Nguyen, Quang-De; Zhao, Xin; Liu, Yang; Davicioni, Elai; Spratt, Daniel E.; Sabbioneda, Simone; Maga, Giovanni; Mucci, Lorelei A.; Ghigna, Claudia; Marchionni, Luigi; Butler, Lisa M.; Ellis, Leigh; Bordeleau, François; Loda, Massimo; Vaira, Valentina; Labbé, David P.; Zadra, Giorgia
Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops
2024 Secchi, Massimiliano; Garbelli, Anna; Riva, Valentina; Deidda, Graziano; Santonicola, Carolina; Formica, Teresa ; Maria, ; Sabbioneda, Simone; Crespan, Emmanuele; Maga, Giovanni
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023 Poggialini, F; Vagaggini, C; Brai, A; Pasqualini, C; Crespan, E; Maga, G; Perini, C; Cabella, N; Botta, L; Musumeci, F; Frosini, M; Schenone, S; Dreassi, E
Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor
2023 Contadini, C; Cirotti, C; Carbone, A; Norouzi, M; Cianciusi, A; Crespan, E; Perini, C; Maga, G; Barilà, D; Musumeci, F; Schenone, S
Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA
2023 Lodola, C; Secchi, M; Sinigiani, V; De Palma, A; Rossi, R; Perico, D; Mauri, Pl; Maga, G
DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective
2022 Secchi, M; Lodola, C; Garbelli, A; Bione, S; Maga, G
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment
2022 Di Maria, S; Picarazzi, F; Mori, M; Cianciusi, A; Carbone, A; Crespan, E; Perini, C; Sabetta, S; Deplano, S; Poggialini, F; Molinari, A; Aronne, R; Maccioni, E; Maga, G; Angelucci, A; Schenone, S; Musumeci, F; Dreassi, E
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
2022 Cesarini, S; Vicenti, I; Poggialini, F; Secchi, M; Giammarino, F; Varasi, I; Lodola, C; Zazzi, M; Dreassi, E; Maga, G; Botta, L; Saladino, R
Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors
2022 Princiotto, S; Musso, L; Manetti, F; Marcellini, V; Maga, G; Crespan, E; Perini, C; Zaffaroni, N; Beretta, Gl; Dallavalle, S
Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect
2022 Martina, Maria Grazia; Sannio, Filomena; Crespan, Emmanuele; Pavone, Marialaura; Simoncini, Alice; Barbieri, Francesca; Perini, Cecilia; Pesce, Emanuela; Maga, Giovanni; Pedemonte, Nicoletta; Docquier, Jean‐denis; Radi, Marco
A role for human dna polymerase λ in alternative lengthening of telomeres
2021 Mentegari, E.; Bertoletti, F.; Kissova, M.; Zucca, E.; Galli, S.; Tagliavini, G.; Garbelli, A.; Maffia, A.; Bione, S.; Ferrari, E.; d'Adda di Fagagna, F.; Francia, S.; Sabbioneda, S.; Chen, L. -Y.; Lingner, J.; Bergoglio, V.; Hoffmann, J. -S.; Hubscher, U.; Crespan, E.; Maga, G.
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIII beta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses
2021 Grazia Martina, M; Vicenti, I; Bauer, L; Crespan, E; Rango, E; Boccuto, A; Olivieri, N; Incerti, M; Zwaagstra, M; Allodi, M; Bertoni, S; Dreassi, E; Zazzi, M; van Kuppeveld, Fjm; Maga, G; Radi, M
High flexibility of rnaseh2 catalytic activity with respect to non-canonical dna structures
2021 Dede, M; Napolitano, S; Melati, A; Pirota, V; Maga, G; Crespan, E
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2
2021 Vicenti, I; Martina, Mg; Boccuto, A; De Angelis, M; Giavarini, G; Dragoni, F; Marchi, S; Trombetta, Cm; Crespan, E; Maga, G; Eydoux, C; Decroly, E; Montomoli, E; Nencioni, L; Zazzi, M; Radi, M
Targeting ddx3x helicase activity with ba103 shows promising therapeutic effects in preclinical glioblastoma models
2021 Brai, A; Riva, V; Clementi, L; Falsitta, L; Zamperini, C; Sinigiani, V; Festuccia, C; Sabetta, S; Aiello, D; Roselli, C; Garbelli, A; Trivisani, Ci; Maccari, L; Bugli, F; Sanguinetti, M; Calandro, P; Chiariello, M; Quaranta, P; Botta, L; Angelucci, A; Maga, G; Botta, M
A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping
2020 Romano, M; Ruggiero, A; Squeglia, F; Maga, G; Berisio, R
DDX3X Inhibitors, an Effective Way to Overcome HIV-1 Resistance Targeting Host Proteins
2020 Brai, A; Riva, V; Saladini, F; Zamperini, C; Trivisani, Ci; Garbelli, A; Pennisi, C; Giannini, A; Boccuto, A; Bugli, F; Martini, M; Sanguinetti, M; Zazzi, M; Dreassi, E; Botta, M; Maga, G
Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor
2020 Brai, A; Boccuto, A; Monti, M; Marchi, S; Vicenti, I; Saladini, F; Trivisani, Ci; Pollutri, A; Trombetta, Cm; Montomoli, E; Riva, V; Garbelli, A; Nola, Em; Zazzi, M; Maga, G; Dreassi, E; Botta, M
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections | 1-gen-2024 | Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco | |
| Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma | 1-gen-2024 | Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia | |
| Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer | 1-gen-2024 | Boufaied, Nadia; Chetta, Paolo; Hallal, Tarek; Cacciatore, Stefano; Lalli, Daniela; Luthold, Carole; Homsy, Kevin; Imada, Eddie L.; Syamala, Sudeepa; Photopoulos, Cornelia; Di Matteo, Anna; de Polo, Anna; Storaci, Alessandra Maria; Huang, Ying; Giunchi, Francesca; Sheridan, Patricia A.; Michelotti, Gregory; Nguyen, Quang-De; Zhao, Xin; Liu, Yang; Davicioni, Elai; Spratt, Daniel E.; Sabbioneda, Simone; Maga, Giovanni; Mucci, Lorelei A.; Ghigna, Claudia; Marchionni, Luigi; Butler, Lisa M.; Ellis, Leigh; Bordeleau, François; Loda, Massimo; Vaira, Valentina; Labbé, David P.; Zadra, Giorgia | |
| Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops | 1-gen-2024 | Secchi, Massimiliano; Garbelli, Anna; Riva, Valentina; Deidda, Graziano; Santonicola, Carolina; Formica, Teresa ; Maria, ; Sabbioneda, Simone; Crespan, Emmanuele; Maga, Giovanni | |
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini, F; Vagaggini, C; Brai, A; Pasqualini, C; Crespan, E; Maga, G; Perini, C; Cabella, N; Botta, L; Musumeci, F; Frosini, M; Schenone, S; Dreassi, E | |
| Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor | 1-gen-2023 | Contadini, C; Cirotti, C; Carbone, A; Norouzi, M; Cianciusi, A; Crespan, E; Perini, C; Maga, G; Barilà, D; Musumeci, F; Schenone, S | |
| Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA | 1-gen-2023 | Lodola, C; Secchi, M; Sinigiani, V; De Palma, A; Rossi, R; Perico, D; Mauri, Pl; Maga, G | |
| DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective | 1-gen-2022 | Secchi, M; Lodola, C; Garbelli, A; Bione, S; Maga, G | |
| Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment | 1-gen-2022 | Di Maria, S; Picarazzi, F; Mori, M; Cianciusi, A; Carbone, A; Crespan, E; Perini, C; Sabetta, S; Deplano, S; Poggialini, F; Molinari, A; Aronne, R; Maccioni, E; Maga, G; Angelucci, A; Schenone, S; Musumeci, F; Dreassi, E | |
| Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity | 1-gen-2022 | Cesarini, S; Vicenti, I; Poggialini, F; Secchi, M; Giammarino, F; Varasi, I; Lodola, C; Zazzi, M; Dreassi, E; Maga, G; Botta, L; Saladino, R | |
| Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors | 1-gen-2022 | Princiotto, S; Musso, L; Manetti, F; Marcellini, V; Maga, G; Crespan, E; Perini, C; Zaffaroni, N; Beretta, Gl; Dallavalle, S | |
| Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect | 1-gen-2022 | Martina, Maria Grazia; Sannio, Filomena; Crespan, Emmanuele; Pavone, Marialaura; Simoncini, Alice; Barbieri, Francesca; Perini, Cecilia; Pesce, Emanuela; Maga, Giovanni; Pedemonte, Nicoletta; Docquier, Jean‐denis; Radi, Marco | |
| A role for human dna polymerase λ in alternative lengthening of telomeres | 1-gen-2021 | Mentegari, E.; Bertoletti, F.; Kissova, M.; Zucca, E.; Galli, S.; Tagliavini, G.; Garbelli, A.; Maffia, A.; Bione, S.; Ferrari, E.; d'Adda di Fagagna, F.; Francia, S.; Sabbioneda, S.; Chen, L. -Y.; Lingner, J.; Bergoglio, V.; Hoffmann, J. -S.; Hubscher, U.; Crespan, E.; Maga, G. | |
| Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIII beta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses | 1-gen-2021 | Grazia Martina, M; Vicenti, I; Bauer, L; Crespan, E; Rango, E; Boccuto, A; Olivieri, N; Incerti, M; Zwaagstra, M; Allodi, M; Bertoni, S; Dreassi, E; Zazzi, M; van Kuppeveld, Fjm; Maga, G; Radi, M | |
| High flexibility of rnaseh2 catalytic activity with respect to non-canonical dna structures | 1-gen-2021 | Dede, M; Napolitano, S; Melati, A; Pirota, V; Maga, G; Crespan, E | |
| System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2 | 1-gen-2021 | Vicenti, I; Martina, Mg; Boccuto, A; De Angelis, M; Giavarini, G; Dragoni, F; Marchi, S; Trombetta, Cm; Crespan, E; Maga, G; Eydoux, C; Decroly, E; Montomoli, E; Nencioni, L; Zazzi, M; Radi, M | |
| Targeting ddx3x helicase activity with ba103 shows promising therapeutic effects in preclinical glioblastoma models | 1-gen-2021 | Brai, A; Riva, V; Clementi, L; Falsitta, L; Zamperini, C; Sinigiani, V; Festuccia, C; Sabetta, S; Aiello, D; Roselli, C; Garbelli, A; Trivisani, Ci; Maccari, L; Bugli, F; Sanguinetti, M; Calandro, P; Chiariello, M; Quaranta, P; Botta, L; Angelucci, A; Maga, G; Botta, M | |
| A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping | 1-gen-2020 | Romano, M; Ruggiero, A; Squeglia, F; Maga, G; Berisio, R | |
| DDX3X Inhibitors, an Effective Way to Overcome HIV-1 Resistance Targeting Host Proteins | 1-gen-2020 | Brai, A; Riva, V; Saladini, F; Zamperini, C; Trivisani, Ci; Garbelli, A; Pennisi, C; Giannini, A; Boccuto, A; Bugli, F; Martini, M; Sanguinetti, M; Zazzi, M; Dreassi, E; Botta, M; Maga, G | |
| Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor | 1-gen-2020 | Brai, A; Boccuto, A; Monti, M; Marchi, S; Vicenti, I; Saladini, F; Trivisani, Ci; Pollutri, A; Trombetta, Cm; Montomoli, E; Riva, V; Garbelli, A; Nola, Em; Zazzi, M; Maga, G; Dreassi, E; Botta, M |