ASUNIS, ISADORA
ASUNIS, ISADORA
Istituto di Ricerca Genetica e Biomedica - IRGB
"in vivo " activation of the human delta globin gene promoter
2005 Marongiu MF; Mascia P; Melis m; Poddie D; Asunis i ; Moi P; Cao A;Ristalid MS
A novel missense mutation (C84R) in a patient with type II vitamin d-dependent rickets.
2010 Asunis I; Marini MG; Porcu L; Meloni A; Cabriolu AL; Cao A; Moi P.
A novel silent beta-thalassemia mutation in the distal CACCC box affects the binding and responsiveness to EKLF.
2004 Moi, P; Faà, V; Marini, Mg; Asunis, I; Ibba, G; Cao, A; Rosatelli, Mc
A Sardinian founder mutation in glycoprotein Ib platelet subunit beta(GP1BB) that impacts thrombocytopenia
2020 Busonero, Fabio; Steri, Maristella; Orru, Valeria; Sole, Gabriella; Olla, Stefania; Marongiu, Michele; Maschio, Andrea; Sidore, Carlo; Lai, Sandra; Mulas, Antonella; Zoledziewska, Magdalena; Floris, Matteo; Pala, Mauro; Forabosco, Paola; Asunis, Isadora; Pitzalis, Maristella; Deidda, Francesca; Masala, Marco; Caria, Cristian Antonio; Barella, Susanna; Abecasis, Goncalo R.; Schlessinger, David; Sanna, Serena; Fiorillo, Edoardo; Cucca, Francesco
BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype.
2008 Uda, M; Galanello, R; Sanna, S; Lettre, G; G Sankaran, V; Usala, G; Busonero, F; Maschio, A; Lai, S; Crisponi, L; Naitza, S; Asunis, I; Deiana, M; Marongiu, M; Porcu, L; Lovicu, M; Nagaraja, R; Perseu, L; Satta, S; Moi, P; H Orkin, S; Al, Et
Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation.
2002 Marini, Mg; Asunis, I; Chan, K; Chan, Jy; Kan, Yw; Porcu, L; Cao, A; Moi, P
Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin
2011 Satta, S; Perseu, L; Moi, P; Asunis, I; Cabriolu, A; Maccioni, L; Demartis, Fr; Manunza, L; Cao, A; Galanello, R
Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice
2017 Manchinu, Maria Francesca; Brancia, Carla; Caria, Cristian Antonio; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, Maria Serafina
Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice
2011 Giuseppina M. Marini; Isadora Asunis; Annalisa Cabriolu; Loredana Porcu; Anna Maria Sau; Francesca Manchinu; Susanna Porcu; Franca M. Marongiu; Daniela Poddie; Lorenza Ronfani; Marco Bianchi; Anotonella Ronchi; Maria Serafina Ristaldi; Antonio Cao;Paolo Moi
Differential Modulation of the ß-Like Globin Genes by KLFs Isolated with a g-Globin CACCC Bait.
2005 Moi, Paolo; Md, ; Porcu, Loredana; Phd, ; G Marini, Maria; Phd, ; Asunis, Isadora; G Loi, Maria; Phd, ; Ikuta, Tohru; Md, ; Cao, Antonio; Md,
Fetal globin gene activation by Klf6.
2008 Porcu, Loredana; G Marini, Maria; Asunis, Isadora; G Loi, Maria; Ikuta, Tohru; Cao, Antonio; Moi, Paolo
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
2008 Manuela Uda; Renzo Galanello; Serena Sanna; Guillaume Lettre; Vijay G. Sankaran; Weimin Chen; Gianluca Usala; Fabio Busonero; Andrea Maschio; Giuseppe Albai; Maria Grazia Piras; Natascia Sestu; Sandra Lai; Mariano Dei; Antonella Mulas; Laura Crisponi; Silvia Naitza; Isadora Asunis; Manila Deiana; Ramaiah Nagaraja; Lucia Perseu; Stefania Satta; Maria Dolores Cipollina; Carla Sollaino; Paolo Moi; Joel N. Hirschhorn; Stuart H. Orkin; Gonçalo R. Abecasis; David Schlessinger;Antonio Cao
HPFH From Klf1 Haploinsufficiency Combined to Transcriptional Heterozygous ?-Thalassemia
2011 Paolo Moi; Giuseppina M. Marini; Isadora Asunis; Loredana Porcu; Annalisa Cabriolu; Stefania Satta; Luciana Perseu; Liliana Maccioni; Antonio Cao;Renzo Galanello
IDENTIFICAZIONE DI UNA NUOVA MUTAZIONE IN POSIZIONE -52 (G->A) DEL BETA DIRECT REPEAT ELEMENT DEL PROMOTORE DEL GENE -GLOBINICO
2010 I. Asunis ; V. Faa ; A. Meloni ; F. Incani ; T. Tuveri ; L. Saba ; R. Puddu ; P. Moi ; M.C. Rosatelli
Identificazione di una nuova mutazione localizzata nel CACCC box distale del gene beta-globinico: studi di espressione in vivo e in vitro
2004 Moi P; Faa' V; Marini MG; Asunis I; Ibba G; Cao A; Rosatelli MC
Impaired LKLF Binding and b-Globin Transactivation in the Thalassemia Mutants of the b-Globin CACCC Box
2003 Pmoi, ; Lporcu, ; Asunis, I; Mgmarini, ; Mgsalgo, ; Gloi, ; Acao,
In vivo activation of the human delta globin gene promoter
2005 Porcu S; Marongiu MF;.Mascia P; Melis M.; Poddie D; Asunis I; Moi P; Cao A.;Ristaldi MS.
INDUCTION OF GAMMA-GLOBIN GENE SYNTHESIS BY CRISPR/CAS9 DELETIONS OF THE HPFH REGION AT - 196 OF THE HBG1 GENE IN beta-K562 AND HUMAN beta-THALASSEMIA HEMATOPOIETIC STEM CELLS
2016 Mingoia, Maura; Giuseppina Marini, M; Asunis, Isadora; Franca Marongiu, M; A Caria, Cristian; Manunza, Laura; Carla Sollaino, M; Gasperini, Daniela; Arras, Marcella; Piga, Giorgio; Piras, Federica; Truca, Marcello; Moi, Paolo
Induction of therapeutic levels of HbF in genome-edited primary beta(0)39-thalassaemia haematopoietic stem and progenitor cells
2020 Mingoia, Maura; Caria Cristian, A; Ye, Lin; Asunis, Isadora; Marongiu, M Franca; Manunza, Laura; Sollaino, M Carla; Wang, Jiaming; Cabriolu, Annalisa; Kurita, Ryo; Nakamura, Yukio; Cucca, Francesco; Kan Yuet, W; Marini, M Giuseppina; Moi, Paolo
Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis
2011 Porcu, S; Manchinu, Mf; Marongiu, Mf; Sogos, V; Poddie, D; Asunis, I; Porcu, L; Marini, Mg; Moi, P; Cao, A; Grosveld, F; Ristaldi, Ms
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| "in vivo " activation of the human delta globin gene promoter | 1-gen-2005 | Marongiu MF; Mascia P; Melis m; Poddie D; Asunis i ; Moi P; Cao A;Ristalid MS | |
| A novel missense mutation (C84R) in a patient with type II vitamin d-dependent rickets. | 1-gen-2010 | Asunis I; Marini MG; Porcu L; Meloni A; Cabriolu AL; Cao A; Moi P. | |
| A novel silent beta-thalassemia mutation in the distal CACCC box affects the binding and responsiveness to EKLF. | 1-gen-2004 | Moi, P; Faà, V; Marini, Mg; Asunis, I; Ibba, G; Cao, A; Rosatelli, Mc | |
| A Sardinian founder mutation in glycoprotein Ib platelet subunit beta(GP1BB) that impacts thrombocytopenia | 1-gen-2020 | Busonero, Fabio; Steri, Maristella; Orru, Valeria; Sole, Gabriella; Olla, Stefania; Marongiu, Michele; Maschio, Andrea; Sidore, Carlo; Lai, Sandra; Mulas, Antonella; Zoledziewska, Magdalena; Floris, Matteo; Pala, Mauro; Forabosco, Paola; Asunis, Isadora; Pitzalis, Maristella; Deidda, Francesca; Masala, Marco; Caria, Cristian Antonio; Barella, Susanna; Abecasis, Goncalo R.; Schlessinger, David; Sanna, Serena; Fiorillo, Edoardo; Cucca, Francesco | |
| BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype. | 1-gen-2008 | Uda, M; Galanello, R; Sanna, S; Lettre, G; G Sankaran, V; Usala, G; Busonero, F; Maschio, A; Lai, S; Crisponi, L; Naitza, S; Asunis, I; Deiana, M; Marongiu, M; Porcu, L; Lovicu, M; Nagaraja, R; Perseu, L; Satta, S; Moi, P; H Orkin, S; Al, Et | |
| Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation. | 1-gen-2002 | Marini, Mg; Asunis, I; Chan, K; Chan, Jy; Kan, Yw; Porcu, L; Cao, A; Moi, P | |
| Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin | 1-gen-2011 | Satta, S; Perseu, L; Moi, P; Asunis, I; Cabriolu, A; Maccioni, L; Demartis, Fr; Manunza, L; Cao, A; Galanello, R | |
| Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice | 1-gen-2017 | Manchinu, Maria Francesca; Brancia, Carla; Caria, Cristian Antonio; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, Maria Serafina | |
| Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice | 1-gen-2011 | Giuseppina M. Marini; Isadora Asunis; Annalisa Cabriolu; Loredana Porcu; Anna Maria Sau; Francesca Manchinu; Susanna Porcu; Franca M. Marongiu; Daniela Poddie; Lorenza Ronfani; Marco Bianchi; Anotonella Ronchi; Maria Serafina Ristaldi; Antonio Cao;Paolo Moi | |
| Differential Modulation of the ß-Like Globin Genes by KLFs Isolated with a g-Globin CACCC Bait. | 1-gen-2005 | Moi, Paolo; Md, ; Porcu, Loredana; Phd, ; G Marini, Maria; Phd, ; Asunis, Isadora; G Loi, Maria; Phd, ; Ikuta, Tohru; Md, ; Cao, Antonio; Md, | |
| Fetal globin gene activation by Klf6. | 1-gen-2008 | Porcu, Loredana; G Marini, Maria; Asunis, Isadora; G Loi, Maria; Ikuta, Tohru; Cao, Antonio; Moi, Paolo | |
| Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. | 1-gen-2008 | Manuela Uda; Renzo Galanello; Serena Sanna; Guillaume Lettre; Vijay G. Sankaran; Weimin Chen; Gianluca Usala; Fabio Busonero; Andrea Maschio; Giuseppe Albai; Maria Grazia Piras; Natascia Sestu; Sandra Lai; Mariano Dei; Antonella Mulas; Laura Crisponi; Silvia Naitza; Isadora Asunis; Manila Deiana; Ramaiah Nagaraja; Lucia Perseu; Stefania Satta; Maria Dolores Cipollina; Carla Sollaino; Paolo Moi; Joel N. Hirschhorn; Stuart H. Orkin; Gonçalo R. Abecasis; David Schlessinger;Antonio Cao | |
| HPFH From Klf1 Haploinsufficiency Combined to Transcriptional Heterozygous ?-Thalassemia | 1-gen-2011 | Paolo Moi; Giuseppina M. Marini; Isadora Asunis; Loredana Porcu; Annalisa Cabriolu; Stefania Satta; Luciana Perseu; Liliana Maccioni; Antonio Cao;Renzo Galanello | |
| IDENTIFICAZIONE DI UNA NUOVA MUTAZIONE IN POSIZIONE -52 (G->A) DEL BETA DIRECT REPEAT ELEMENT DEL PROMOTORE DEL GENE -GLOBINICO | 1-gen-2010 | I. Asunis ; V. Faa ; A. Meloni ; F. Incani ; T. Tuveri ; L. Saba ; R. Puddu ; P. Moi ; M.C. Rosatelli | |
| Identificazione di una nuova mutazione localizzata nel CACCC box distale del gene beta-globinico: studi di espressione in vivo e in vitro | 1-gen-2004 | Moi P; Faa' V; Marini MG; Asunis I; Ibba G; Cao A; Rosatelli MC | |
| Impaired LKLF Binding and b-Globin Transactivation in the Thalassemia Mutants of the b-Globin CACCC Box | 1-gen-2003 | Pmoi, ; Lporcu, ; Asunis, I; Mgmarini, ; Mgsalgo, ; Gloi, ; Acao, | |
| In vivo activation of the human delta globin gene promoter | 1-gen-2005 | Porcu S; Marongiu MF;.Mascia P; Melis M.; Poddie D; Asunis I; Moi P; Cao A.;Ristaldi MS. | |
| INDUCTION OF GAMMA-GLOBIN GENE SYNTHESIS BY CRISPR/CAS9 DELETIONS OF THE HPFH REGION AT - 196 OF THE HBG1 GENE IN beta-K562 AND HUMAN beta-THALASSEMIA HEMATOPOIETIC STEM CELLS | 1-gen-2016 | Mingoia, Maura; Giuseppina Marini, M; Asunis, Isadora; Franca Marongiu, M; A Caria, Cristian; Manunza, Laura; Carla Sollaino, M; Gasperini, Daniela; Arras, Marcella; Piga, Giorgio; Piras, Federica; Truca, Marcello; Moi, Paolo | |
| Induction of therapeutic levels of HbF in genome-edited primary beta(0)39-thalassaemia haematopoietic stem and progenitor cells | 1-gen-2020 | Mingoia, Maura; Caria Cristian, A; Ye, Lin; Asunis, Isadora; Marongiu, M Franca; Manunza, Laura; Sollaino, M Carla; Wang, Jiaming; Cabriolu, Annalisa; Kurita, Ryo; Nakamura, Yukio; Cucca, Francesco; Kan Yuet, W; Marini, M Giuseppina; Moi, Paolo | |
| Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis | 1-gen-2011 | Porcu, S; Manchinu, Mf; Marongiu, Mf; Sogos, V; Poddie, D; Asunis, I; Porcu, L; Marini, Mg; Moi, P; Cao, A; Grosveld, F; Ristaldi, Ms |