ASUNIS, ISADORA
ASUNIS, ISADORA
Istituto di Ricerca Genetica e Biomedica - IRGB
A Sardinian founder mutation in glycoprotein Ib platelet subunit beta(GP1BB) that impacts thrombocytopenia
2020 Busonero, Fabio; Steri, Maristella; Orru, Valeria; Sole, Gabriella; Olla, Stefania; Marongiu, Michele; Maschio, Andrea; Sidore, Carlo; Lai, Sandra; Mulas, Antonella; Zoledziewska, Magdalena; Floris, Matteo; Pala, Mauro; Forabosco, Paola; Asunis, Isadora; Pitzalis, Maristella; Deidda, Francesca; Masala, Marco; Caria, Cristian Antonio; Barella, Susanna; Abecasis, Goncalo R.; Schlessinger, David; Sanna, Serena; Fiorillo, Edoardo; Cucca, Francesco
Induction of therapeutic levels of HbF in genome-edited primary beta(0)39-thalassaemia haematopoietic stem and progenitor cells
2020 Mingoia, Maura; Caria Cristian, A; Ye, Lin; Asunis, Isadora; Marongiu, M Franca; Manunza, Laura; Sollaino, M Carla; Wang, Jiaming; Cabriolu, Annalisa; Kurita, Ryo; Nakamura, Yukio; Cucca, Francesco; Kan Yuet, W; Marini, M Giuseppina; Moi, Paolo
Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice
2017 Manchinu, Maria Francesca; Brancia, Carla; Caria, Cristian Antonio; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, Maria Serafina
Overexpression of the Cytokine BAFF and Autoimmunity Risk
2017 Steri, M.; Orru, V.; Idda, M. L.; Pitzalis, M.; Pala, M.; Zara, I.; Sidore, C.; Faa, V.; Floris, M.; Deiana, M.; Asunis, I.; Porcu, E.; Mulas, A.; Piras, M. G.; Lobina, M.; Lai, S.; Marongiu, M.; Serra, V.; Marongiu, M.; Sole, G.; Busonero, F.; Maschio, A.; Cusano, R.; Cuccuru, G.; Deidda, F.; Poddie, F.; Farina, G.; Dei, M.; Virdis, F.; Olla, S.; Satta, M. A.; Pani, M.; Delitala, A.; Cocco, E.; Frau, J.; Coghe, G.; Lorefice, L.; Fenu, G.; Ferrigno, P.; Ban, M.; Barizzone, N.; Leone, M.; Guerini, F. R.; Piga, M.; Firinu, D.; Kockum, I.; Bomfim, I. Lima; Olsson, T.; Alfredsson, L.; Suarez, A.; Carreira, P. E.; CastilloPalma, M. J.; Marcus, J. H.; Congia, M.; Angius, A.; Melis, M.; Gonzalez, A.; Riquelme, M. E. A.; da Silva, B. M.; Marchini, M.; Danieli, M. G.; Del Giacco, S.; Mathieu, A.; Pani, A.; Montgomery, S. B.; Rosati, G.; Hillert, J.; Sawcer, S.; D'Alfonso, S.; Todd, J. A.; Novembre, J.; Abecasis, G. R.; Whalen, M. B.; Marrosu, M. G.; Meloni, A.; Sanna, S.; Gorospe, M.; Schlessinger, D.; Fiorillo, E.; Zoledziewska, M.; Cucca, F.
INDUCTION OF GAMMA-GLOBIN GENE SYNTHESIS BY CRISPR/CAS9 DELETIONS OF THE HPFH REGION AT - 196 OF THE HBG1 GENE IN beta-K562 AND HUMAN beta-THALASSEMIA HEMATOPOIETIC STEM CELLS
2016 Mingoia, Maura; Giuseppina Marini, M; Asunis, Isadora; Franca Marongiu, M; A Caria, Cristian; Manunza, Laura; Carla Sollaino, M; Gasperini, Daniela; Arras, Marcella; Piga, Giorgio; Piras, Federica; Truca, Marcello; Moi, Paolo
Novel action of FOXL2 as mediator of Col1a2 gene autoregulation
2016 Marongiu, Mara; Deiana, Manila; Marcia, Loredana; Sbardellati, Andrea; Asunis, Isadora; Meloni, Alessandra; Angius, Andrea; Cusano, Roberto; Loi, Angela; Crobu, Francesca; Fotia, Giorgio; Cucca, Francesco; Schlessinger, David; Crisponi, Laura
Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia.
2014 Cucca F; Steri M; Pitzalis M; Zoledziewska M; Orrù V; Zara I; Porcu E; Mulas A; Deidda F; Asunis I; Sole G; Virdis F; Murru R; Whalen M; Busonero F; Maschio A; Angius A; Jones C; Cocco E; Costa G; Mancosu C; Frau J; Lorena L; Fenu G; Coghe G; Melis M; Sanna So; Poddie F; Idda ML; Morelli L; Farina G; Cossu P; Melis M; Ferrigno P; Sidore C; Rosati G; D'Alfonso S; Faa V; Olla S; Pala M; Abecasis GR; Meloni A; Floris M; Fiorillo E; Marrosu MG; Sanna Se.
Post GWAS analysis of a BCL11A intronic region to define its role in regulating HbF levels
2013 Francesca Anedda; Sonia Sanna; Isadora Asunis; Gianluca Usala; Danjou Fabrice; Cristian Antonio Caria; Luciana Perseu; Alessia Loi; Annalisa Cabriolu; Loredana Porcu; Maria Giuseppina Marini; Maria Franca Marongiu; ;Carlo Sidore; ;Riccardo Berutti; Mauro Pala; ;Angius Andrea; Fabio Busonero;Andrea Maschio; Stefania Satta; Francarosa Demartis; Liliana Maccioni; Ramaiah Nagaraja; Goncalo Abecasis; David Schlessinger; Maria Serafina Ristaldi; Renzo Galanello; Paolo Moi ;Francesco Cucca; Serena Sanna; Uda Manuela.
Post GWAS analysis of the BCL11A intronic region to define its role in regulating HbF levels.
2012 F. Anedda; S. Sanna; I. Asunis; G. Usala; F. Danjou; L. Perseu; A. Cabriolu; C. A. Caria; L. Porcu; M. G. Marini; M. F. Marongiu; C. Sidore; R. Berutti; M. Pala; A. Angius; F. Busonero; A. Maschio; S. Satta; F. Demartis; L. Maccioni; A. Meloni; R. Nagaraja; G. Abecasis; D. Schlessinger; M. S. Ristaldi; R. Galanello; P. Moi; F. Cucca; S. Sanna; M. Uda
Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin
2011 Satta, S; Perseu, L; Moi, P; Asunis, I; Cabriolu, A; Maccioni, L; Demartis, Fr; Manunza, L; Cao, A; Galanello, R
Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice
2011 Giuseppina M. Marini; Isadora Asunis; Annalisa Cabriolu; Loredana Porcu; Anna Maria Sau; Francesca Manchinu; Susanna Porcu; Franca M. Marongiu; Daniela Poddie; Lorenza Ronfani; Marco Bianchi; Anotonella Ronchi; Maria Serafina Ristaldi; Antonio Cao;Paolo Moi
HPFH From Klf1 Haploinsufficiency Combined to Transcriptional Heterozygous ?-Thalassemia
2011 Paolo Moi; Giuseppina M. Marini; Isadora Asunis; Loredana Porcu; Annalisa Cabriolu; Stefania Satta; Luciana Perseu; Liliana Maccioni; Antonio Cao;Renzo Galanello
Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis
2011 Porcu, S; Manchinu, Mf; Marongiu, Mf; Sogos, V; Poddie, D; Asunis, I; Porcu, L; Marini, Mg; Moi, P; Cao, A; Grosveld, F; Ristaldi, Ms
A novel missense mutation (C84R) in a patient with type II vitamin d-dependent rickets.
2010 Asunis I; Marini MG; Porcu L; Meloni A; Cabriolu AL; Cao A; Moi P.
IDENTIFICAZIONE DI UNA NUOVA MUTAZIONE IN POSIZIONE -52 (G->A) DEL BETA DIRECT REPEAT ELEMENT DEL PROMOTORE DEL GENE -GLOBINICO
2010 I. Asunis ; V. Faa ; A. Meloni ; F. Incani ; T. Tuveri ; L. Saba ; R. Puddu ; P. Moi ; M.C. Rosatelli
Regulation of the human HBA genes by KLF4 in erythroid cell lines.
2010 Marini, Mg; Porcu, L; Asunis, I; Loi, Mg; Ristaldi, Ms; Porcu, S; Ikuta, T; Cao, A; Moi, P
BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype.
2008 Uda, M; Galanello, R; Sanna, S; Lettre, G; G Sankaran, V; Usala, G; Busonero, F; Maschio, A; Lai, S; Crisponi, L; Naitza, S; Asunis, I; Deiana, M; Marongiu, M; Porcu, L; Lovicu, M; Nagaraja, R; Perseu, L; Satta, S; Moi, P; H Orkin, S; Al, Et
Fetal globin gene activation by Klf6.
2008 Porcu, Loredana; G Marini, Maria; Asunis, Isadora; G Loi, Maria; Ikuta, Tohru; Cao, Antonio; Moi, Paolo
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
2008 Manuela Uda; Renzo Galanello; Serena Sanna; Guillaume Lettre; Vijay G. Sankaran; Weimin Chen; Gianluca Usala; Fabio Busonero; Andrea Maschio; Giuseppe Albai; Maria Grazia Piras; Natascia Sestu; Sandra Lai; Mariano Dei; Antonella Mulas; Laura Crisponi; Silvia Naitza; Isadora Asunis; Manila Deiana; Ramaiah Nagaraja; Lucia Perseu; Stefania Satta; Maria Dolores Cipollina; Carla Sollaino; Paolo Moi; Joel N. Hirschhorn; Stuart H. Orkin; Gonçalo R. Abecasis; David Schlessinger;Antonio Cao
Regulation of the Human Alpha-Globin Genes by GKLF
2008 Paolo Moi; MD; Giuseppina Maria Marini; PhD; Loredana Porcu; PhD; Isadora Asunis; Maria Giuseppina Loi; Lisa Anna Cabriolu;Antonio Cao; M.D.;
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Sardinian founder mutation in glycoprotein Ib platelet subunit beta(GP1BB) that impacts thrombocytopenia | 1-gen-2020 | Busonero, Fabio; Steri, Maristella; Orru, Valeria; Sole, Gabriella; Olla, Stefania; Marongiu, Michele; Maschio, Andrea; Sidore, Carlo; Lai, Sandra; Mulas, Antonella; Zoledziewska, Magdalena; Floris, Matteo; Pala, Mauro; Forabosco, Paola; Asunis, Isadora; Pitzalis, Maristella; Deidda, Francesca; Masala, Marco; Caria, Cristian Antonio; Barella, Susanna; Abecasis, Goncalo R.; Schlessinger, David; Sanna, Serena; Fiorillo, Edoardo; Cucca, Francesco | |
| Induction of therapeutic levels of HbF in genome-edited primary beta(0)39-thalassaemia haematopoietic stem and progenitor cells | 1-gen-2020 | Mingoia, Maura; Caria Cristian, A; Ye, Lin; Asunis, Isadora; Marongiu, M Franca; Manunza, Laura; Sollaino, M Carla; Wang, Jiaming; Cabriolu, Annalisa; Kurita, Ryo; Nakamura, Yukio; Cucca, Francesco; Kan Yuet, W; Marini, M Giuseppina; Moi, Paolo | |
| Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice | 1-gen-2017 | Manchinu, Maria Francesca; Brancia, Carla; Caria, Cristian Antonio; Musu, Ester; Porcu, Susanna; Simbula, Michela; Asunis, Isadora; Perseu, Lucia; Ristaldi, Maria Serafina | |
| Overexpression of the Cytokine BAFF and Autoimmunity Risk | 1-gen-2017 | Steri, M.; Orru, V.; Idda, M. L.; Pitzalis, M.; Pala, M.; Zara, I.; Sidore, C.; Faa, V.; Floris, M.; Deiana, M.; Asunis, I.; Porcu, E.; Mulas, A.; Piras, M. G.; Lobina, M.; Lai, S.; Marongiu, M.; Serra, V.; Marongiu, M.; Sole, G.; Busonero, F.; Maschio, A.; Cusano, R.; Cuccuru, G.; Deidda, F.; Poddie, F.; Farina, G.; Dei, M.; Virdis, F.; Olla, S.; Satta, M. A.; Pani, M.; Delitala, A.; Cocco, E.; Frau, J.; Coghe, G.; Lorefice, L.; Fenu, G.; Ferrigno, P.; Ban, M.; Barizzone, N.; Leone, M.; Guerini, F. R.; Piga, M.; Firinu, D.; Kockum, I.; Bomfim, I. Lima; Olsson, T.; Alfredsson, L.; Suarez, A.; Carreira, P. E.; CastilloPalma, M. J.; Marcus, J. H.; Congia, M.; Angius, A.; Melis, M.; Gonzalez, A.; Riquelme, M. E. A.; da Silva, B. M.; Marchini, M.; Danieli, M. G.; Del Giacco, S.; Mathieu, A.; Pani, A.; Montgomery, S. B.; Rosati, G.; Hillert, J.; Sawcer, S.; D'Alfonso, S.; Todd, J. A.; Novembre, J.; Abecasis, G. R.; Whalen, M. B.; Marrosu, M. G.; Meloni, A.; Sanna, S.; Gorospe, M.; Schlessinger, D.; Fiorillo, E.; Zoledziewska, M.; Cucca, F. | |
| INDUCTION OF GAMMA-GLOBIN GENE SYNTHESIS BY CRISPR/CAS9 DELETIONS OF THE HPFH REGION AT - 196 OF THE HBG1 GENE IN beta-K562 AND HUMAN beta-THALASSEMIA HEMATOPOIETIC STEM CELLS | 1-gen-2016 | Mingoia, Maura; Giuseppina Marini, M; Asunis, Isadora; Franca Marongiu, M; A Caria, Cristian; Manunza, Laura; Carla Sollaino, M; Gasperini, Daniela; Arras, Marcella; Piga, Giorgio; Piras, Federica; Truca, Marcello; Moi, Paolo | |
| Novel action of FOXL2 as mediator of Col1a2 gene autoregulation | 1-gen-2016 | Marongiu, Mara; Deiana, Manila; Marcia, Loredana; Sbardellati, Andrea; Asunis, Isadora; Meloni, Alessandra; Angius, Andrea; Cusano, Roberto; Loi, Angela; Crobu, Francesca; Fotia, Giorgio; Cucca, Francesco; Schlessinger, David; Crisponi, Laura | |
| Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia. | 1-gen-2014 | Cucca F; Steri M; Pitzalis M; Zoledziewska M; Orrù V; Zara I; Porcu E; Mulas A; Deidda F; Asunis I; Sole G; Virdis F; Murru R; Whalen M; Busonero F; Maschio A; Angius A; Jones C; Cocco E; Costa G; Mancosu C; Frau J; Lorena L; Fenu G; Coghe G; Melis M; Sanna So; Poddie F; Idda ML; Morelli L; Farina G; Cossu P; Melis M; Ferrigno P; Sidore C; Rosati G; D'Alfonso S; Faa V; Olla S; Pala M; Abecasis GR; Meloni A; Floris M; Fiorillo E; Marrosu MG; Sanna Se. | |
| Post GWAS analysis of a BCL11A intronic region to define its role in regulating HbF levels | 1-gen-2013 | Francesca Anedda; Sonia Sanna; Isadora Asunis; Gianluca Usala; Danjou Fabrice; Cristian Antonio Caria; Luciana Perseu; Alessia Loi; Annalisa Cabriolu; Loredana Porcu; Maria Giuseppina Marini; Maria Franca Marongiu; ;Carlo Sidore; ;Riccardo Berutti; Mauro Pala; ;Angius Andrea; Fabio Busonero;Andrea Maschio; Stefania Satta; Francarosa Demartis; Liliana Maccioni; Ramaiah Nagaraja; Goncalo Abecasis; David Schlessinger; Maria Serafina Ristaldi; Renzo Galanello; Paolo Moi ;Francesco Cucca; Serena Sanna; Uda Manuela. | |
| Post GWAS analysis of the BCL11A intronic region to define its role in regulating HbF levels. | 1-gen-2012 | F. Anedda; S. Sanna; I. Asunis; G. Usala; F. Danjou; L. Perseu; A. Cabriolu; C. A. Caria; L. Porcu; M. G. Marini; M. F. Marongiu; C. Sidore; R. Berutti; M. Pala; A. Angius; F. Busonero; A. Maschio; S. Satta; F. Demartis; L. Maccioni; A. Meloni; R. Nagaraja; G. Abecasis; D. Schlessinger; M. S. Ristaldi; R. Galanello; P. Moi; F. Cucca; S. Sanna; M. Uda | |
| Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin | 1-gen-2011 | Satta, S; Perseu, L; Moi, P; Asunis, I; Cabriolu, A; Maccioni, L; Demartis, Fr; Manunza, L; Cao, A; Galanello, R | |
| Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice | 1-gen-2011 | Giuseppina M. Marini; Isadora Asunis; Annalisa Cabriolu; Loredana Porcu; Anna Maria Sau; Francesca Manchinu; Susanna Porcu; Franca M. Marongiu; Daniela Poddie; Lorenza Ronfani; Marco Bianchi; Anotonella Ronchi; Maria Serafina Ristaldi; Antonio Cao;Paolo Moi | |
| HPFH From Klf1 Haploinsufficiency Combined to Transcriptional Heterozygous ?-Thalassemia | 1-gen-2011 | Paolo Moi; Giuseppina M. Marini; Isadora Asunis; Loredana Porcu; Annalisa Cabriolu; Stefania Satta; Luciana Perseu; Liliana Maccioni; Antonio Cao;Renzo Galanello | |
| Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis | 1-gen-2011 | Porcu, S; Manchinu, Mf; Marongiu, Mf; Sogos, V; Poddie, D; Asunis, I; Porcu, L; Marini, Mg; Moi, P; Cao, A; Grosveld, F; Ristaldi, Ms | |
| A novel missense mutation (C84R) in a patient with type II vitamin d-dependent rickets. | 1-gen-2010 | Asunis I; Marini MG; Porcu L; Meloni A; Cabriolu AL; Cao A; Moi P. | |
| IDENTIFICAZIONE DI UNA NUOVA MUTAZIONE IN POSIZIONE -52 (G->A) DEL BETA DIRECT REPEAT ELEMENT DEL PROMOTORE DEL GENE -GLOBINICO | 1-gen-2010 | I. Asunis ; V. Faa ; A. Meloni ; F. Incani ; T. Tuveri ; L. Saba ; R. Puddu ; P. Moi ; M.C. Rosatelli | |
| Regulation of the human HBA genes by KLF4 in erythroid cell lines. | 1-gen-2010 | Marini, Mg; Porcu, L; Asunis, I; Loi, Mg; Ristaldi, Ms; Porcu, S; Ikuta, T; Cao, A; Moi, P | |
| BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype. | 1-gen-2008 | Uda, M; Galanello, R; Sanna, S; Lettre, G; G Sankaran, V; Usala, G; Busonero, F; Maschio, A; Lai, S; Crisponi, L; Naitza, S; Asunis, I; Deiana, M; Marongiu, M; Porcu, L; Lovicu, M; Nagaraja, R; Perseu, L; Satta, S; Moi, P; H Orkin, S; Al, Et | |
| Fetal globin gene activation by Klf6. | 1-gen-2008 | Porcu, Loredana; G Marini, Maria; Asunis, Isadora; G Loi, Maria; Ikuta, Tohru; Cao, Antonio; Moi, Paolo | |
| Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. | 1-gen-2008 | Manuela Uda; Renzo Galanello; Serena Sanna; Guillaume Lettre; Vijay G. Sankaran; Weimin Chen; Gianluca Usala; Fabio Busonero; Andrea Maschio; Giuseppe Albai; Maria Grazia Piras; Natascia Sestu; Sandra Lai; Mariano Dei; Antonella Mulas; Laura Crisponi; Silvia Naitza; Isadora Asunis; Manila Deiana; Ramaiah Nagaraja; Lucia Perseu; Stefania Satta; Maria Dolores Cipollina; Carla Sollaino; Paolo Moi; Joel N. Hirschhorn; Stuart H. Orkin; Gonçalo R. Abecasis; David Schlessinger;Antonio Cao | |
| Regulation of the Human Alpha-Globin Genes by GKLF | 1-gen-2008 | Paolo Moi; MD; Giuseppina Maria Marini; PhD; Loredana Porcu; PhD; Isadora Asunis; Maria Giuseppina Loi; Lisa Anna Cabriolu;Antonio Cao; M.D.; |