SIMEONE, ANTONIO
SIMEONE, ANTONIO
Istituto di genetica e biofisica "Adriano Buzzati Traverso"- IGB - Sede Napoli
Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson's Disease in Italian Patients
2023 Nicole Piera Palomba ; Giorgio Fortunato ; Giuseppe Pepe ; Nicola Modugno ; Sara Pietracupa ; Immacolata Damiano ; Giada Mascio ; Federica Carrillo ; Luca Giovanni Di Giovannantonio ; Laura Ianiro ; Katiuscia Martinello ; Viola Volpato ; Vincenzo Desiato ; Riccardo Acri ; Marianna Storto ; Ferdinando Nicoletti ; Caleb Webber ; Antonio Simeone ; Sergio Fucile ; Vittorio Maglione ; Teresa Esposito
Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage
2021 Di Giovannantonio L.; Acampora D.; Omodei D.; Nigro V.; Barba P.; Barbieri E.; Chambers I.; Simeone A.
Identification of sixteen novel candidate genes for late onset Parkinson's disease
2021 Gialluisi A.; Reccia M.G.; Modugno N.; Nutile T.; Lombardi A.; Di Giovannantonio L.G.; Pietracupa S.; Ruggiero D.; Scala S.; Gambardella S.; Iacoviello L.; Gianfrancesco F.; Acampora D.; D'Esposito M.; Simeone A.; Ciullo M.; Esposito T.
Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population
2020 Gialluisi, A; Reccia, Mg; Tirozzi, A; Nutile, T; Lombardi, A; De Sanctis, C; Varanese, S; Pietracupa, S; Modugno, N; Simeone, A; Ciullo, M; Esposito, T
Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors.
2019 Imbriglio T; Verhaeghe R; Martinello K; Pascarelli MT; Chece G; Bucci D; Notartomaso S; Quattromani M; Mascio G; Scalabrì F; Simeone A; Maccari S; Del Percio C; Wieloch T; Fucile S; Babiloni C; Battaglia G; Limatola C; Nicoletti F; Cannella M.
Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies
2018 Rosati, J; Ferrari, D; Altieri, F; Tardivo, S; Ricciolini, C; Fusilli, C; Zalfa, C; Profico, Dc; Pinos, F; Bernardini, L; Torres, B; Manni, I; Piaggio, G; Binda, E; Copetti, M; Lamorte, G; Mazza, T; Carella, M; Gelati, M; Valente, Em; Simeone, A; Vescovi, Al
OTX2 restricts entry to the mouse germline.
2018 Zhang, J; Zhang, M; Acampora, D; Vojtek, M; Yuan, D; Simeone, A; Chambers, I
Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells.
2017 Acampora D; Di Giovannantonio LG; Garofalo A; Nigro V; Omodei D; Lombardi A; Zhang J; Chambers I; Simeone A.
Genetic Otx2 mis-localization delays critical period plasticity across brain regions
2017 Lee, H H C; Bernard, C; Ye, Z; Acampora, D; Simeone, A; Prochiantz, A; Di Nardo, A A; Hensch, T K
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast
2016 Acampora D.; Omodei D.; Petrosino G.; Garofalo A.; Savarese M.; Nigro V.; Di Giovannantonio L.G.; Mercadante V.; Simeone A.
A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1+/- mice.
2015 Zhang J; Götz S; Vogt Weisenhorn DM; Simeone A; Wurst W; Prakash N.
Dickkopf 3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse
2015 Fukusumi Y.; Meier F.; Gotz S.; Matheus F.; Irmler M.; Beckervordersandforth R.; FausKessler T.; Minina E.; Rauser B.; Zhang J.; Arenas E.; Andersson E.; Niehrs C.; Beckers J.; Simeone A.; Wurst W.; Prakash N.
Dynamics of the imprinting maintenance ZFP57/KAP1 and associated factors network at DNA methylated targets in pluripotent ES cells and insights into a potential developmental/differentiation role
2015 Lad, S; DE FEIS, Italia; Verde, G; Cammisa, M; Riso, V; Kukreja, H; Manganelli, G; Filosa, S; Fico, A; Bellenchi, G; Baglivo, I; Pedone, Pv; Simeone, A; Riccio, A; Angelini, C; Grimaldi, G
Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons
2015 Kim H.T.; Kim S.J.; Sohn Y.I.; Paik S.S.; Caplette R.; Simonutti M.; Moon K.H.; Lee E.J.; Min K.W.; Kim M.J.; Lee D.G.; Simeone A.; Lamonerie T.; Furukawa T.; Choi J.S.; Kweon H.S.; Picaud S.; Kim I.B.; Shong M.; Kim J.W.
FGF/FGFR2 Signaling Regulates the Generation and Correct Positioning of Bergmann Glia Cells in the Developing Mouse Cerebellum
2014 Meier, Florian; Giesert, Florian; Delic, Sabit; FausKessler, Theresa; Matheus, Friederike; Simeone, Antonio; Hoelter, Sabine M.; Kuehn, Ralf; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang; Prakash, Nilima
Genome-wide profiling of the imprinting maintenance factor ZFP57 and associated chromatin regulators in murine embryonal stem cells at imprinted and non-imprinted loci and its role in the neural development of the mouse embryo
2014 Lad, S; Defeis, I; Cammisa, M; Manganelli, G; Filosa, S; Bellenchi, G; Simeone, A; Riccio, A; Angelini, C; Grimaldi, G
Genomic association of the imprinting maintenance factor ZFP57 and associated chromatin regulators in murine embryonal stem cells at imprinted and non imprinted loci and its expression in the developing mouse embryo
2014 S. LAD; I. Defeis; M. Cammisa; G. Verde; V. Riso; G. Manganelli; S. Filosa; G. Bellenchi; A. Simeone; A. Riccio; C. Angelini; G. GRIMALDI
Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes.
2014 Bernard C; Kim HT; Ibad RT; Lee EJ; Simonutti M; Picaud S; Acampora D; Simeone A; Di Nardo AA; Prochiantz A; Moya KL; Kim JW.
Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex.
2014 Kim, N; Acampora, D; Dingli, F; Loew, D; Simeone, A; Prochiantz, A; A Di Nardo, A
Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility.
2014 Tripathi, Pp; Di Giovannantonio, Lg; Sanguinetti, E; Acampora, D; Allegra, M; Caleo, M; Wurst, W; Simeone, A; Bozzi, Y
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson's Disease in Italian Patients | 1-gen-2023 | Nicole Piera Palomba ; Giorgio Fortunato ; Giuseppe Pepe ; Nicola Modugno ; Sara Pietracupa ; Immacolata Damiano ; Giada Mascio ; Federica Carrillo ; Luca Giovanni Di Giovannantonio ; Laura Ianiro ; Katiuscia Martinello ; Viola Volpato ; Vincenzo Desiato ; Riccardo Acri ; Marianna Storto ; Ferdinando Nicoletti ; Caleb Webber ; Antonio Simeone ; Sergio Fucile ; Vittorio Maglione ; Teresa Esposito | |
| Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage | 1-gen-2021 | Di Giovannantonio L.; Acampora D.; Omodei D.; Nigro V.; Barba P.; Barbieri E.; Chambers I.; Simeone A. | |
| Identification of sixteen novel candidate genes for late onset Parkinson's disease | 1-gen-2021 | Gialluisi A.; Reccia M.G.; Modugno N.; Nutile T.; Lombardi A.; Di Giovannantonio L.G.; Pietracupa S.; Ruggiero D.; Scala S.; Gambardella S.; Iacoviello L.; Gianfrancesco F.; Acampora D.; D'Esposito M.; Simeone A.; Ciullo M.; Esposito T. | |
| Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population | 1-gen-2020 | Gialluisi, A; Reccia, Mg; Tirozzi, A; Nutile, T; Lombardi, A; De Sanctis, C; Varanese, S; Pietracupa, S; Modugno, N; Simeone, A; Ciullo, M; Esposito, T | |
| Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors. | 1-gen-2019 | Imbriglio T; Verhaeghe R; Martinello K; Pascarelli MT; Chece G; Bucci D; Notartomaso S; Quattromani M; Mascio G; Scalabrì F; Simeone A; Maccari S; Del Percio C; Wieloch T; Fucile S; Babiloni C; Battaglia G; Limatola C; Nicoletti F; Cannella M. | |
| Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies | 1-gen-2018 | Rosati, J; Ferrari, D; Altieri, F; Tardivo, S; Ricciolini, C; Fusilli, C; Zalfa, C; Profico, Dc; Pinos, F; Bernardini, L; Torres, B; Manni, I; Piaggio, G; Binda, E; Copetti, M; Lamorte, G; Mazza, T; Carella, M; Gelati, M; Valente, Em; Simeone, A; Vescovi, Al | |
| OTX2 restricts entry to the mouse germline. | 1-gen-2018 | Zhang, J; Zhang, M; Acampora, D; Vojtek, M; Yuan, D; Simeone, A; Chambers, I | |
| Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells. | 1-gen-2017 | Acampora D; Di Giovannantonio LG; Garofalo A; Nigro V; Omodei D; Lombardi A; Zhang J; Chambers I; Simeone A. | |
| Genetic Otx2 mis-localization delays critical period plasticity across brain regions | 1-gen-2017 | Lee, H H C; Bernard, C; Ye, Z; Acampora, D; Simeone, A; Prochiantz, A; Di Nardo, A A; Hensch, T K | |
| Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast | 1-gen-2016 | Acampora D.; Omodei D.; Petrosino G.; Garofalo A.; Savarese M.; Nigro V.; Di Giovannantonio L.G.; Mercadante V.; Simeone A. | |
| A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1+/- mice. | 1-gen-2015 | Zhang J; Götz S; Vogt Weisenhorn DM; Simeone A; Wurst W; Prakash N. | |
| Dickkopf 3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse | 1-gen-2015 | Fukusumi Y.; Meier F.; Gotz S.; Matheus F.; Irmler M.; Beckervordersandforth R.; FausKessler T.; Minina E.; Rauser B.; Zhang J.; Arenas E.; Andersson E.; Niehrs C.; Beckers J.; Simeone A.; Wurst W.; Prakash N. | |
| Dynamics of the imprinting maintenance ZFP57/KAP1 and associated factors network at DNA methylated targets in pluripotent ES cells and insights into a potential developmental/differentiation role | 1-gen-2015 | Lad, S; DE FEIS, Italia; Verde, G; Cammisa, M; Riso, V; Kukreja, H; Manganelli, G; Filosa, S; Fico, A; Bellenchi, G; Baglivo, I; Pedone, Pv; Simeone, A; Riccio, A; Angelini, C; Grimaldi, G | |
| Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons | 1-gen-2015 | Kim H.T.; Kim S.J.; Sohn Y.I.; Paik S.S.; Caplette R.; Simonutti M.; Moon K.H.; Lee E.J.; Min K.W.; Kim M.J.; Lee D.G.; Simeone A.; Lamonerie T.; Furukawa T.; Choi J.S.; Kweon H.S.; Picaud S.; Kim I.B.; Shong M.; Kim J.W. | |
| FGF/FGFR2 Signaling Regulates the Generation and Correct Positioning of Bergmann Glia Cells in the Developing Mouse Cerebellum | 1-gen-2014 | Meier, Florian; Giesert, Florian; Delic, Sabit; FausKessler, Theresa; Matheus, Friederike; Simeone, Antonio; Hoelter, Sabine M.; Kuehn, Ralf; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang; Prakash, Nilima | |
| Genome-wide profiling of the imprinting maintenance factor ZFP57 and associated chromatin regulators in murine embryonal stem cells at imprinted and non-imprinted loci and its role in the neural development of the mouse embryo | 1-gen-2014 | Lad, S; Defeis, I; Cammisa, M; Manganelli, G; Filosa, S; Bellenchi, G; Simeone, A; Riccio, A; Angelini, C; Grimaldi, G | |
| Genomic association of the imprinting maintenance factor ZFP57 and associated chromatin regulators in murine embryonal stem cells at imprinted and non imprinted loci and its expression in the developing mouse embryo | 1-gen-2014 | S. LAD; I. Defeis; M. Cammisa; G. Verde; V. Riso; G. Manganelli; S. Filosa; G. Bellenchi; A. Simeone; A. Riccio; C. Angelini; G. GRIMALDI | |
| Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes. | 1-gen-2014 | Bernard C; Kim HT; Ibad RT; Lee EJ; Simonutti M; Picaud S; Acampora D; Simeone A; Di Nardo AA; Prochiantz A; Moya KL; Kim JW. | |
| Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex. | 1-gen-2014 | Kim, N; Acampora, D; Dingli, F; Loew, D; Simeone, A; Prochiantz, A; A Di Nardo, A | |
| Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility. | 1-gen-2014 | Tripathi, Pp; Di Giovannantonio, Lg; Sanguinetti, E; Acampora, D; Allegra, M; Caleo, M; Wurst, W; Simeone, A; Bozzi, Y |