TIRONE, FELICE
TIRONE, FELICE
Istituto di Biochimica e Biologia Cellulare - IBBC - Sede Secondaria Monterotondo
Intracerebellar administration of the chemokine Cxcl3 reduces the volume of medulloblastoma lesions at an advanced stage by promoting the migration and differentiation of preneoplastic precursor cells
2024 Ceccarelli, Manuela; Rossi, Sabrina; Bonaventura, Fabrizio; Massari, Roberto; D'Elia, Annunziata; Soluri, Andrea; Micheli, Laura; D'Andrea, Giorgio; Mancini, Barbara; Raspa, Marcello; Scavizzi, Ferdinando; Alaggio, Rita; Del Bufalo, Francesca; Miele, Evelina; Carai, Andrea; Mastronuzzi, Angela; Tirone, Felice
Cyclin D3 deficiency promotes a slower, more oxidative skeletal muscle phenotype and ameliorates pathophysiology in the mdx mouse model of Duchenne muscular dystrophy
2023 Bonato, Agnese; Raparelli, Giada; Luvisetto, Siro; Forconi, Flavia; Cosentino, Marianna; Tirone, Felice; Rizzuto, Emanuele; Caruso, Maurizia
Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota
2023 Micheli, Laura; Bertini, Laura; Bonato, Agnese; Villanova, Noemi; Caruso, Carla; Caruso, Maurizia; Bernini, Roberta; Tirone, Felice
Transcriptome analysis reveals genes associated with stem cell activation by physical exercise in the dentate gyrus of aged p16Ink4a knockout mice.
2023 Micheli, Laura; D'Andrea, Giorgio; Creanza, TERESA MARIA; Volpe, Daniel; Ancona, Nicola; Scardigli, Raffaella; Tirone, Felice
Adult hippocampal neurogenesis and social behavioural deficits in the R451C Neuroligin3 mouse model of autism are reverted by the antidepressant fluoxetine
2022 Gioia, Roberta; Seri, Tommaso; Diamanti, Tamara; Fimmano, Stefania; Vitale, Marina; Ahlenius, Henrik; Kokaia, Zaal; Tirone, Felice; Micheli, Laura; Biagioni, Stefano; Lupo, Giuseppe; Rinaldi, Arianna; De Jaco, Antonella; Cacci, Emanuele
Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neurogenesis
2021 Micheli, L; Creanza, Tm; Ceccarelli, M; D'Andrea, G; Giacovazzo, G; Ancona, N; Coccurello, R; Scardigli, R; Tirone, F
Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/-/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611
2021 Ceccarelli, Manuela; D'Andrea, Giorgio; Micheli, Laura; Gentile, Giulia; Cavallaro, Sebastiano; Merlino, Giuseppe; Papoff, Giuliana; Tirone, Felice
Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor Frequency
2020 Ceccarelli, M; D'Andrea, G; Micheli, L; Tirone, F
Hydroxytyrosol stimulates neurogenesis in aged dentate gyrus by enhancing stem and progenitor cell proliferation and neuron survival
2020 D'Andrea, Giorgio; Ceccarelli, Manuela; Bernini, Roberta; Santi, Luca; Caruso, Carla; Micheli, Laura; Tirone, Felice; Clemente, Mariangela
Interaction Between Neurogenic Stimuli and the Gene Network Controlling the Activation of Stem Cells of the Adult Neurogenic Niches, in Physiological and Pathological Conditions
2020 Ceccarelli, Manuela; D'Andrea, Giorgio; Micheli, Laura; Tirone, Felice
p16Ink4a Prevents the Activation of Aged Quiescent Dentate Gyrus Stem Cells by Physical Exercise
2019 Micheli, Laura; D'Andrea, Giorgio; Ceccarelli, Manuela; Ferri, Alessandra; Scardigli, Raffaella; Tirone, Felice
Running-Activated Neural Stem Cells Enhance Subventricular Neurogenesis and Improve Olfactory Behavior in p21 Knockout Mice.
2019 Nicolis di Robilant, V; Scardigli, R; Strimpakos, G; Tirone, F; Middei, S; Scopa, C; De Bardi, M; Battistini, L; Saraulli, D; Farioli Vecchioli, S
Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise
2018 Micheli, Laura; Ceccarelli, Manuela; D'Andrea, Giorgio; Tirone, Felice
Fluoxetine or Sox2 reactivate proliferation-defective stem and progenitor cells of the adult and aged dentate gyrus
2018 Micheli, L; Ceccarelli, M; D'Andrea, G; Costanzi, M; Giacovazzo, G; Coccurello, R; Caruso, C; Tirone, F.
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-?-OTX2-SNAIL via PTEN inhibition
2018 Ferrucci, V; De Antonellis, P; Pennino, Fp; Asadzadeh, F; Virgilio, A; Montanaro, D; Galeone, A; Boffa, I; Pisano, I; Scognamiglio, I; Navas, L; Diana, D; Pedone, E; Gargiulo, S; Gramanzini, M; Brunetti, A; Danielson, L; Carotenuto, M; Liguori, L; Verrico, A; Quaglietta, L; Errico, Me; Del Monaco, V; D'Argenio, V; Tirone, F; Mastronuzzi, A; Donofrio, V; Giangaspero, F; Picard, D; Remke, M; Garzia, L; Daniels, C; Delattre, O; Swartling, Fj; Weiss, Wa; Salvatore, F; Fattorusso, R; Chesler, L; Taylor, Md; Cinalli, G; Zollo, M
Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model
2018 Presutti, Dario; Ceccarelli, Manuela; Micheli, Laura; Papoff, Giuliana; Santini, Simonetta; Samperna, Simone; Lalli, Cristiana; Zentilin, Lorena; Ruberti, Giovina; Tirone, Felice
Physical exercise rescues defective neural stem cells and neurogenesis in the adult subventricular zone of Btg1 knockout mice.
2017 Mastrorilli, Valentina; Scopa, Chiara; Saraulli, Daniele; Costanzi, Marco; Scardigli, Raffaella; Rouault, Jeanpierre; Fariolivecchioli, Stefano; Tirone, Felice
Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2
2017 Micheli, Laura; Ceccarelli, Manuela; Gioia, Roberta; D'Andrea, Giorgio; Fariolivecchioli, Stefano; Costanzi, Marco; Saraulli, Daniele; Cestari, Vincenzo; Tirone, Felice
Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development
2016 Gentile, Giulia; Ceccarelli, Manuela; Micheli, Laura; Tirone, Felice; Cavallaro, Sebastiano
HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression
2016 Micheli L; D'Andrea G; Leonardi L; Tirone F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Intracerebellar administration of the chemokine Cxcl3 reduces the volume of medulloblastoma lesions at an advanced stage by promoting the migration and differentiation of preneoplastic precursor cells | 1-gen-2024 | Ceccarelli, Manuela; Rossi, Sabrina; Bonaventura, Fabrizio; Massari, Roberto; D'Elia, Annunziata; Soluri, Andrea; Micheli, Laura; D'Andrea, Giorgio; Mancini, Barbara; Raspa, Marcello; Scavizzi, Ferdinando; Alaggio, Rita; Del Bufalo, Francesca; Miele, Evelina; Carai, Andrea; Mastronuzzi, Angela; Tirone, Felice | |
| Cyclin D3 deficiency promotes a slower, more oxidative skeletal muscle phenotype and ameliorates pathophysiology in the mdx mouse model of Duchenne muscular dystrophy | 1-gen-2023 | Bonato, Agnese; Raparelli, Giada; Luvisetto, Siro; Forconi, Flavia; Cosentino, Marianna; Tirone, Felice; Rizzuto, Emanuele; Caruso, Maurizia | |
| Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota | 1-gen-2023 | Micheli, Laura; Bertini, Laura; Bonato, Agnese; Villanova, Noemi; Caruso, Carla; Caruso, Maurizia; Bernini, Roberta; Tirone, Felice | |
| Transcriptome analysis reveals genes associated with stem cell activation by physical exercise in the dentate gyrus of aged p16Ink4a knockout mice. | 1-gen-2023 | Micheli, Laura; D'Andrea, Giorgio; Creanza, TERESA MARIA; Volpe, Daniel; Ancona, Nicola; Scardigli, Raffaella; Tirone, Felice | |
| Adult hippocampal neurogenesis and social behavioural deficits in the R451C Neuroligin3 mouse model of autism are reverted by the antidepressant fluoxetine | 1-gen-2022 | Gioia, Roberta; Seri, Tommaso; Diamanti, Tamara; Fimmano, Stefania; Vitale, Marina; Ahlenius, Henrik; Kokaia, Zaal; Tirone, Felice; Micheli, Laura; Biagioni, Stefano; Lupo, Giuseppe; Rinaldi, Arianna; De Jaco, Antonella; Cacci, Emanuele | |
| Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neurogenesis | 1-gen-2021 | Micheli, L; Creanza, Tm; Ceccarelli, M; D'Andrea, G; Giacovazzo, G; Ancona, N; Coccurello, R; Scardigli, R; Tirone, F | |
| Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/-/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611 | 1-gen-2021 | Ceccarelli, Manuela; D'Andrea, Giorgio; Micheli, Laura; Gentile, Giulia; Cavallaro, Sebastiano; Merlino, Giuseppe; Papoff, Giuliana; Tirone, Felice | |
| Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor Frequency | 1-gen-2020 | Ceccarelli, M; D'Andrea, G; Micheli, L; Tirone, F | |
| Hydroxytyrosol stimulates neurogenesis in aged dentate gyrus by enhancing stem and progenitor cell proliferation and neuron survival | 1-gen-2020 | D'Andrea, Giorgio; Ceccarelli, Manuela; Bernini, Roberta; Santi, Luca; Caruso, Carla; Micheli, Laura; Tirone, Felice; Clemente, Mariangela | |
| Interaction Between Neurogenic Stimuli and the Gene Network Controlling the Activation of Stem Cells of the Adult Neurogenic Niches, in Physiological and Pathological Conditions | 1-gen-2020 | Ceccarelli, Manuela; D'Andrea, Giorgio; Micheli, Laura; Tirone, Felice | |
| p16Ink4a Prevents the Activation of Aged Quiescent Dentate Gyrus Stem Cells by Physical Exercise | 1-gen-2019 | Micheli, Laura; D'Andrea, Giorgio; Ceccarelli, Manuela; Ferri, Alessandra; Scardigli, Raffaella; Tirone, Felice | |
| Running-Activated Neural Stem Cells Enhance Subventricular Neurogenesis and Improve Olfactory Behavior in p21 Knockout Mice. | 1-gen-2019 | Nicolis di Robilant, V; Scardigli, R; Strimpakos, G; Tirone, F; Middei, S; Scopa, C; De Bardi, M; Battistini, L; Saraulli, D; Farioli Vecchioli, S | |
| Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise | 1-gen-2018 | Micheli, Laura; Ceccarelli, Manuela; D'Andrea, Giorgio; Tirone, Felice | |
| Fluoxetine or Sox2 reactivate proliferation-defective stem and progenitor cells of the adult and aged dentate gyrus | 1-gen-2018 | Micheli, L; Ceccarelli, M; D'Andrea, G; Costanzi, M; Giacovazzo, G; Coccurello, R; Caruso, C; Tirone, F. | |
| Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-?-OTX2-SNAIL via PTEN inhibition | 1-gen-2018 | Ferrucci, V; De Antonellis, P; Pennino, Fp; Asadzadeh, F; Virgilio, A; Montanaro, D; Galeone, A; Boffa, I; Pisano, I; Scognamiglio, I; Navas, L; Diana, D; Pedone, E; Gargiulo, S; Gramanzini, M; Brunetti, A; Danielson, L; Carotenuto, M; Liguori, L; Verrico, A; Quaglietta, L; Errico, Me; Del Monaco, V; D'Argenio, V; Tirone, F; Mastronuzzi, A; Donofrio, V; Giangaspero, F; Picard, D; Remke, M; Garzia, L; Daniels, C; Delattre, O; Swartling, Fj; Weiss, Wa; Salvatore, F; Fattorusso, R; Chesler, L; Taylor, Md; Cinalli, G; Zollo, M | |
| Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model | 1-gen-2018 | Presutti, Dario; Ceccarelli, Manuela; Micheli, Laura; Papoff, Giuliana; Santini, Simonetta; Samperna, Simone; Lalli, Cristiana; Zentilin, Lorena; Ruberti, Giovina; Tirone, Felice | |
| Physical exercise rescues defective neural stem cells and neurogenesis in the adult subventricular zone of Btg1 knockout mice. | 1-gen-2017 | Mastrorilli, Valentina; Scopa, Chiara; Saraulli, Daniele; Costanzi, Marco; Scardigli, Raffaella; Rouault, Jeanpierre; Fariolivecchioli, Stefano; Tirone, Felice | |
| Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2 | 1-gen-2017 | Micheli, Laura; Ceccarelli, Manuela; Gioia, Roberta; D'Andrea, Giorgio; Fariolivecchioli, Stefano; Costanzi, Marco; Saraulli, Daniele; Cestari, Vincenzo; Tirone, Felice | |
| Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development | 1-gen-2016 | Gentile, Giulia; Ceccarelli, Manuela; Micheli, Laura; Tirone, Felice; Cavallaro, Sebastiano | |
| HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression | 1-gen-2016 | Micheli L; D'Andrea G; Leonardi L; Tirone F. |