VILLA, ANNA
VILLA, ANNA
Istituto di Tecnologie Biomediche - ITB
Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning
2024 Penna, S; Zecchillo, A; Di Verniere, M; Fontana, E; Iannello, V; Palagano, E; Mantero, S; Andrea, Cappelleri; Rizzoli, E; Santi, L; Crisafulli, L; Filibian, M; Forlino, A; Basso-Ricci, L; Scala, S; Scanziani, E; Schinke, T; Ficara, F; Sobacchi, C; Villa, A; Capo, V
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency
2024 Castiello, M. C.; Brandas, C.; Ferrari, S.; Porcellini, S.; Sacchetti, N.; Canarutto, D.; Draghici, E.; Merelli, I.; Barcella, M.; Pelosi, G.; Vavassori, V.; Varesi, A.; Jacob, A.; Scala, S.; Ricci, L. B.; Paulis, M.; Strina, D.; Di Verniere, M.; Sergi, L. S.; Serafini, M.; Holland, S. M.; Bergerson, J. R. E.; De Ravin, S. S.; Malech, H. L.; Pala, F.; Bosticardo, M.; Brombin, C.; Cugnata, F.; Calzoni, E.; Crooks, G. M.; Notarangelo, L. D.; Genovese, P.; Naldini, L.; Villa, A.
Pneumocystis murina lesions in lungs of experimentally infected Cd40l–/– mice
2024 Cappelleri, A.; Canesi, S.; Bertola, L.; Capo, V.; Zecchillo, A.; Albano, L.; Villa, A.; Scanziani, E.; Recordati, C.
HyperIgE in hypomorphic recombination-activating gene defects
2023 Castiello, MARIA CARMINA; Brandas, Chiara; Capo, Valentina; Villa, Anna
Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations
2023 Castiello, Maria Carmina; Di Verniere, Martina; Draghici, Elena; Fontana, Elena; Penna, Sara; Sereni, Lucia; Zecchillo, Alessandra; Minuta, Denise; Uva, Paolo; Zahn, Marco; GilFarina, Irene; Annoni, Andrea; Iaia, Silvia; Ott de Bruin, Lisa M.; Notarangelo, Luigi D.; PikeOverzet, Karin; Staal, Frank J.T.; Villa, Anna; Capo, Valentina
Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4+ T-cells for the treatment of Hyper IgM1
2023 Canarutto, Daniele; Asperti, Claudia; Vavassori, Valentina; Porcellini, Simona; Rovelli, Elisabetta; Paulis, Marianna; Ferrari, Samuele; Varesi, Angelica; Fiumara, Martina; Jacob, Aurelien; Sergi Sergi, Lucia; Visigalli, Ilaria; Ferrua, Francesca; GonzálezGranado Luis, Ignacio; Lougaris, Vassilios; Finocchi, Andrea; Villa, Anna; Radrizzani, Marina; Naldini, Luigi
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells
2022 Ferrari, Samuele; Jacob, Aurelien; Cesana, Daniela; Laugel, Marianne; Beretta, Stefano; Varesi, Angelica; Unali, Giulia; Conti, Anastasia; Canarutto, Daniele; Albano, Luisa; Calabria, Andrea; Vavassori, Valentina; Cipriani, Carlo; Castiello, Maria Carmina; Esposito, Simona; Brombin, Chiara; Cugnata, Federica; Adjali, Oumeya; Ayuso, Eduard; Merelli, Ivan; Villa, Anna; Di Micco, Raffaella; KajasteRudnitski, Anna; Montini, Eugenio; PenaudBudloo, Magalie; Naldini, Luigi
Osteoclast rich osteopetrosis due to defects in the TCIRG1 gene
2022 Capo, Valentina; Abinun, Mario; Villa, Anna
A novel intronic variant in PIGB in Acrofrontofacionasal dysostosis type 1 patients expands the spectrum of phenotypes associated with GPI biosynthesis defects
2021 Palagano E.; Gordon C.T.; Uva P.; Strina D.; Dimartino C.; Villa A.; Amiel J.; GuionAlmeida M.L.; VendraminiPittoli S.; KokitsuNakata N.M.; ZechiCeide R.M.; Sobacchi C.
Autosomal recessive osteopetrosis: Mechanisms and treatments
2021 Penna, Sara; Villa, Anna; Capo, Valentina
Expanded circulating hematopoietic stem/ progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis
2021 Capo, Valentina; Penna, Sara; Merelli, Ivan; Barcella, Matteo; Scala, Serena; Bassoricci, Luca; Draghici, Elena; Palagano, Eleonora; Zonari, Erika; Desantis, Giacomo; Uva, Paolo; Cusano, Roberto; Sergi Lucia, Sergi; Crisafulli, Laura; Moshous, Despina; Stepensky, Polina; Drabko, Katarzyna; Kaya, Zühre; Unal, Ekrem; Gezdiric, Alper; Menna, Giuseppe; Serafini, Marta; Aiuti, Alessandro; Locatelli Silvia, Laura; Carlostella, Carmelo; Schulz Ansgar, S; Ficara, Francesca; Sobacchi, Cristina; Gentner, Bernhard; Villa, Anna
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome
2021 Vavassori, Valentina; Mercuri, Elisabetta; Marcovecchio, Genni E.; Castiello, Maria C.; Schiroli, Giulia; Albano, Luisa; Margulies, Carrie; Buquicchio, Frank; Fontana, Elena; Beretta, Stefano; Merelli, Ivan; Cappelleri, Andrea; Rancoita, Paola M.V.; Lougaris, Vassilios; Plebani, Alessandro; Kanariou, Maria; Lankester, Arjan; Ferrua, Francesca; Scanziani, Eugenio; CottaRamusino, Cecilia; Villa, Anna; Naldini, Luigi; Genovese, Pietro
Pathobiologic Mechanisms of Neurodegeneration in Osteopetrosis Derived from Structural and Functional Analysis of 14 ClC-7 Mutants
2021 Di Zanni, Eleonora; Palagano, Eleonora; Lagostena, Laura; Strina, Dario; Rehman, Asma; Abinun, Mario; De Somer, Lien; Martire, Baldassarre; Brown, Justin; Kariminejad, Ariana; Balasubramanian, Shanti; Baynam, Gareth; Gurrieri, Fiorella; A Pisanti, Maria; De Maggio, Ilaria; R Abboud, Miguel; Chiesa, Robert; P Burren, Christine; Villa, Anna; Sobacchi, Cristina; Picollo, Alessandra
PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm
2021 Muggeo, Sharon; Crisafulli, Laura; Uva, Paolo; Fontana, Elena; Ubezio, Marta; Morenghi, Emanuela; Colombo, Federico Simone; Rigoni, Rosita; Peano, Clelia; Vezzoni, Paolo; Della Porta, Matteo Giovanni; Villa, Anna; Ficara, Francesca
Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients
2021 Marcovecchio, Genni Enza; Ferrua, Francesca; Fontana, Elena; Beretta, Stefano; Genua, Marco; Bortolomai, Ileana; Conti, Anastasia; Montin, Davide; Cascarano, Maria Teresa; Bergante, Sonia; D'Oria, Veronica; Giamberti, Alessandro; Amodio, Donato; Cancrini, Caterina; Carotti, Adriano; Di Micco, Raffaella; Merelli, Ivan; Bosticardo, Marita; Villa, Anna
Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia
2020 Bosticardo, M; Pala, F; Calzoni, E; Delmonte, Om; Dobbs, K; Gardner, Cl; Sacchetti, N; Kawai, T; Garabedian, Ek; Draper, D; Bergerson, Jre; Deravin, Ss; Freeman, Af; Gungor, T; Hartog, N; Holland, Sm; Kohn, Db; Malech, Hl; Markert, Ml; Weinacht, Kg; Villa, A; Seet, Cs; Montelhagen, A; Crooks, Gm; Notarangelo, Ld
Chromosome Transplantation: A Possible Approach to Treat Human X-linked Disorders
2020 Paulis, M; Susani, L; Castelli, A; Suzuki, T; Hara, T; Straniero, L; Duga, S; Strina, D; Mantero, S; Caldana, E; Sergi, Ls; Villa, A; Vezzoni, P
Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn syndrome
2020 Rigoni, R; Fontana, E; Dobbs, K; Marrella, V; Taverniti, V; Maina, V; Facoetti, A; D'Amico, G; Alherz, W; Cruzmunoz, Me; Schuetz, C; Gennery, Ar; Garabedian, Ek; Giliani, S; Draper, D; Dbaibo, G; Geha, Rs; Meyts, I; Tousseyn, T; Neven, B; Moshous, D; Fischer, A; Schulz, A; Finocchi, A; Kuhns, Db; Fink, Dl; Lionakis, Ms; Swamydas, M; Guglielmetti, S; Alejo, J; Myles, Ia; Pittaluga, S; Notarangelo, Ld; Villa, A; Cassani, B
Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency
2020 Castiello M.C.; Bosticardo M.; Sacchetti N.; Calzoni E.; Fontana E.; Yamazaki Y.; Draghici E.; Corsino C.; Bortolomai I.; Sereni L.; Yu H.H.; Uva P.; Palchaudhuri R.; Scadden D.T.; Villa A.; Notarangelo L.D.
Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis
2020 Valentina Capo; Sara Penna; Ivan Merelli; Matteo Barcella; Serena Scala; Luca BassoRicci; Elena Draghici; Eleonora Palagano; Erika Zonari; Giacomo Desantis; Paolo Uva; Roberto Cusano; Lucia Sergi Sergi; Laura Crisafulli; Despina Moshous; Polina Stepensky; Katarzyna Drabko; Zühre Kaya; Ekrem Unal; Alper Gezdirici; Giuseppe Menna; Marta Serafini; Alessandro Aiuti; Silvia Laura Locatelli; Carmelo CarloStella; Ansgar S. Schulz; Francesca Ficara; Cristina Sobacchi; Bernhard Gentner;Anna Villa
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning | 1-gen-2024 | Penna, S; Zecchillo, A; Di Verniere, M; Fontana, E; Iannello, V; Palagano, E; Mantero, S; Andrea, Cappelleri; Rizzoli, E; Santi, L; Crisafulli, L; Filibian, M; Forlino, A; Basso-Ricci, L; Scala, S; Scanziani, E; Schinke, T; Ficara, F; Sobacchi, C; Villa, A; Capo, V | |
| Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency | 1-gen-2024 | Castiello, M. C.; Brandas, C.; Ferrari, S.; Porcellini, S.; Sacchetti, N.; Canarutto, D.; Draghici, E.; Merelli, I.; Barcella, M.; Pelosi, G.; Vavassori, V.; Varesi, A.; Jacob, A.; Scala, S.; Ricci, L. B.; Paulis, M.; Strina, D.; Di Verniere, M.; Sergi, L. S.; Serafini, M.; Holland, S. M.; Bergerson, J. R. E.; De Ravin, S. S.; Malech, H. L.; Pala, F.; Bosticardo, M.; Brombin, C.; Cugnata, F.; Calzoni, E.; Crooks, G. M.; Notarangelo, L. D.; Genovese, P.; Naldini, L.; Villa, A. | |
| Pneumocystis murina lesions in lungs of experimentally infected Cd40l–/– mice | 1-gen-2024 | Cappelleri, A.; Canesi, S.; Bertola, L.; Capo, V.; Zecchillo, A.; Albano, L.; Villa, A.; Scanziani, E.; Recordati, C. | |
| HyperIgE in hypomorphic recombination-activating gene defects | 1-gen-2023 | Castiello, MARIA CARMINA; Brandas, Chiara; Capo, Valentina; Villa, Anna | |
| Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations | 1-gen-2023 | Castiello, Maria Carmina; Di Verniere, Martina; Draghici, Elena; Fontana, Elena; Penna, Sara; Sereni, Lucia; Zecchillo, Alessandra; Minuta, Denise; Uva, Paolo; Zahn, Marco; GilFarina, Irene; Annoni, Andrea; Iaia, Silvia; Ott de Bruin, Lisa M.; Notarangelo, Luigi D.; PikeOverzet, Karin; Staal, Frank J.T.; Villa, Anna; Capo, Valentina | |
| Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4<sup>+</sup> T-cells for the treatment of Hyper IgM1 | 1-gen-2023 | Canarutto, Daniele; Asperti, Claudia; Vavassori, Valentina; Porcellini, Simona; Rovelli, Elisabetta; Paulis, Marianna; Ferrari, Samuele; Varesi, Angelica; Fiumara, Martina; Jacob, Aurelien; Sergi Sergi, Lucia; Visigalli, Ilaria; Ferrua, Francesca; GonzálezGranado Luis, Ignacio; Lougaris, Vassilios; Finocchi, Andrea; Villa, Anna; Radrizzani, Marina; Naldini, Luigi | |
| Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells | 1-gen-2022 | Ferrari, Samuele; Jacob, Aurelien; Cesana, Daniela; Laugel, Marianne; Beretta, Stefano; Varesi, Angelica; Unali, Giulia; Conti, Anastasia; Canarutto, Daniele; Albano, Luisa; Calabria, Andrea; Vavassori, Valentina; Cipriani, Carlo; Castiello, Maria Carmina; Esposito, Simona; Brombin, Chiara; Cugnata, Federica; Adjali, Oumeya; Ayuso, Eduard; Merelli, Ivan; Villa, Anna; Di Micco, Raffaella; KajasteRudnitski, Anna; Montini, Eugenio; PenaudBudloo, Magalie; Naldini, Luigi | |
| Osteoclast rich osteopetrosis due to defects in the TCIRG1 gene | 1-gen-2022 | Capo, Valentina; Abinun, Mario; Villa, Anna | |
| A novel intronic variant in PIGB in Acrofrontofacionasal dysostosis type 1 patients expands the spectrum of phenotypes associated with GPI biosynthesis defects | 1-gen-2021 | Palagano E.; Gordon C.T.; Uva P.; Strina D.; Dimartino C.; Villa A.; Amiel J.; GuionAlmeida M.L.; VendraminiPittoli S.; KokitsuNakata N.M.; ZechiCeide R.M.; Sobacchi C. | |
| Autosomal recessive osteopetrosis: Mechanisms and treatments | 1-gen-2021 | Penna, Sara; Villa, Anna; Capo, Valentina | |
| Expanded circulating hematopoietic stem/ progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis | 1-gen-2021 | Capo, Valentina; Penna, Sara; Merelli, Ivan; Barcella, Matteo; Scala, Serena; Bassoricci, Luca; Draghici, Elena; Palagano, Eleonora; Zonari, Erika; Desantis, Giacomo; Uva, Paolo; Cusano, Roberto; Sergi Lucia, Sergi; Crisafulli, Laura; Moshous, Despina; Stepensky, Polina; Drabko, Katarzyna; Kaya, Zühre; Unal, Ekrem; Gezdiric, Alper; Menna, Giuseppe; Serafini, Marta; Aiuti, Alessandro; Locatelli Silvia, Laura; Carlostella, Carmelo; Schulz Ansgar, S; Ficara, Francesca; Sobacchi, Cristina; Gentner, Bernhard; Villa, Anna | |
| Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome | 1-gen-2021 | Vavassori, Valentina; Mercuri, Elisabetta; Marcovecchio, Genni E.; Castiello, Maria C.; Schiroli, Giulia; Albano, Luisa; Margulies, Carrie; Buquicchio, Frank; Fontana, Elena; Beretta, Stefano; Merelli, Ivan; Cappelleri, Andrea; Rancoita, Paola M.V.; Lougaris, Vassilios; Plebani, Alessandro; Kanariou, Maria; Lankester, Arjan; Ferrua, Francesca; Scanziani, Eugenio; CottaRamusino, Cecilia; Villa, Anna; Naldini, Luigi; Genovese, Pietro | |
| Pathobiologic Mechanisms of Neurodegeneration in Osteopetrosis Derived from Structural and Functional Analysis of 14 ClC-7 Mutants | 1-gen-2021 | Di Zanni, Eleonora; Palagano, Eleonora; Lagostena, Laura; Strina, Dario; Rehman, Asma; Abinun, Mario; De Somer, Lien; Martire, Baldassarre; Brown, Justin; Kariminejad, Ariana; Balasubramanian, Shanti; Baynam, Gareth; Gurrieri, Fiorella; A Pisanti, Maria; De Maggio, Ilaria; R Abboud, Miguel; Chiesa, Robert; P Burren, Christine; Villa, Anna; Sobacchi, Cristina; Picollo, Alessandra | |
| PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm | 1-gen-2021 | Muggeo, Sharon; Crisafulli, Laura; Uva, Paolo; Fontana, Elena; Ubezio, Marta; Morenghi, Emanuela; Colombo, Federico Simone; Rigoni, Rosita; Peano, Clelia; Vezzoni, Paolo; Della Porta, Matteo Giovanni; Villa, Anna; Ficara, Francesca | |
| Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients | 1-gen-2021 | Marcovecchio, Genni Enza; Ferrua, Francesca; Fontana, Elena; Beretta, Stefano; Genua, Marco; Bortolomai, Ileana; Conti, Anastasia; Montin, Davide; Cascarano, Maria Teresa; Bergante, Sonia; D'Oria, Veronica; Giamberti, Alessandro; Amodio, Donato; Cancrini, Caterina; Carotti, Adriano; Di Micco, Raffaella; Merelli, Ivan; Bosticardo, Marita; Villa, Anna | |
| Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia | 1-gen-2020 | Bosticardo, M; Pala, F; Calzoni, E; Delmonte, Om; Dobbs, K; Gardner, Cl; Sacchetti, N; Kawai, T; Garabedian, Ek; Draper, D; Bergerson, Jre; Deravin, Ss; Freeman, Af; Gungor, T; Hartog, N; Holland, Sm; Kohn, Db; Malech, Hl; Markert, Ml; Weinacht, Kg; Villa, A; Seet, Cs; Montelhagen, A; Crooks, Gm; Notarangelo, Ld | |
| Chromosome Transplantation: A Possible Approach to Treat Human X-linked Disorders | 1-gen-2020 | Paulis, M; Susani, L; Castelli, A; Suzuki, T; Hara, T; Straniero, L; Duga, S; Strina, D; Mantero, S; Caldana, E; Sergi, Ls; Villa, A; Vezzoni, P | |
| Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn syndrome | 1-gen-2020 | Rigoni, R; Fontana, E; Dobbs, K; Marrella, V; Taverniti, V; Maina, V; Facoetti, A; D'Amico, G; Alherz, W; Cruzmunoz, Me; Schuetz, C; Gennery, Ar; Garabedian, Ek; Giliani, S; Draper, D; Dbaibo, G; Geha, Rs; Meyts, I; Tousseyn, T; Neven, B; Moshous, D; Fischer, A; Schulz, A; Finocchi, A; Kuhns, Db; Fink, Dl; Lionakis, Ms; Swamydas, M; Guglielmetti, S; Alejo, J; Myles, Ia; Pittaluga, S; Notarangelo, Ld; Villa, A; Cassani, B | |
| Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency | 1-gen-2020 | Castiello M.C.; Bosticardo M.; Sacchetti N.; Calzoni E.; Fontana E.; Yamazaki Y.; Draghici E.; Corsino C.; Bortolomai I.; Sereni L.; Yu H.H.; Uva P.; Palchaudhuri R.; Scadden D.T.; Villa A.; Notarangelo L.D. | |
| Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis | 1-gen-2020 | Valentina Capo; Sara Penna; Ivan Merelli; Matteo Barcella; Serena Scala; Luca BassoRicci; Elena Draghici; Eleonora Palagano; Erika Zonari; Giacomo Desantis; Paolo Uva; Roberto Cusano; Lucia Sergi Sergi; Laura Crisafulli; Despina Moshous; Polina Stepensky; Katarzyna Drabko; Zühre Kaya; Ekrem Unal; Alper Gezdirici; Giuseppe Menna; Marta Serafini; Alessandro Aiuti; Silvia Laura Locatelli; Carmelo CarloStella; Ansgar S. Schulz; Francesca Ficara; Cristina Sobacchi; Bernhard Gentner;Anna Villa |