VITALE, ROSA MARIA
VITALE, ROSA MARIA
Istituto di Chimica Biomolecolare - ICB - Sede Pozzuoli
Eukaryotic Initiation Translation Factor 2A activation by cannabidiolic acid alters the protein homeostasis balance in glioblastoma cells
2024 Bellone, Maria Laura; Syed, Azmal Ali; Vitale, Rosa Maria; Sigismondo, Gianluca; Mensitieri, Francesca; Pollastro, Federica; Amodeo, Pietro; Appendino, Giovanni; De Tommasi, Nunziatina; Krijgsveld, Jeroen; Piaz, Fabrizio Dal
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists
2024 Kosar, Miroslav; Sarott, Roman C.; Sykes, David A.; Viray, Alexander E. G.; Vitale, Rosa Maria; Tomašević, Nataša; Li, Xiaoting; Ganzoni, Rudolf L. Z.; Kicin, Bilal; Reichert, Lisa; Patej, Kacper J.; Gómez-Bouzó, Uxía; Guba, Wolfgang; Mccormick, Peter J.; Hua, Tian; Gruber, Christian W.; Veprintsev, Dmitry B.; Frank, James A.; Grether, Uwe; Carreira, Erick M.
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE‐1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Studies
2024 Vitale, ROSA MARIA; Maria Morace, Andrea; D'Errico, Antonio; Ricciardi, Federica; Fusco, Antimo; Boccella, Serena; Guida, Francesca; Nasso, Rosarita; Rading, Sebastian; Karsak, Meliha; Caprioglio, Diego; Iannotti, FABIO ARTURO; Arcone, Rosaria; Luongo, Livio; Masullo, Mariorosario; Maione, Sabatino; Amodeo, Pietro
Phytochemical Characterization and TRPA1/TRPM8 Modulation Profile of the Cannabigerol-Rich Cannabis sativa L. Chemotype IV
2024 Gargiulo, Ernesto; Moriello, Aniello Schiano; Benetti, Emanuele; Pagni, Luca; Arnoldi, Lolita; De Petrocellis, Luciano; Chianese, Giuseppina; Vitale, Rosa Maria; Taglialatela-Scafati, Orazio
Editorial: "Small molecules targeting transmembrane receptors and ion channels in drug discovery"
2023 Vitale, ROSA MARIA; Iannotti, FABIO ARTURO; Florio, Tullio
Marine Natural and Nature-Inspired Compounds Targeting Peroxisome Proliferator Activated Receptors (PPARs)
2023 D'Aniello, Enrico; Amodeo, Pietro; Vitale, ROSA MARIA
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells
2023 Kosar, Miroslav; A Sykes, David; G Viray, Alexander E; Vitale, ROSA MARIA; C Sarott, Roman; L Ganzoni, Rudolf; Onion, David; M Tobias, Janelle; Leippe, Philipp; Ullmer, Christoph; A Zirwes, Elisabeth; Guba, Wolfgang; Grether, Uwe; A Frank, James; B Veprintsev, Dmitry; M Carreira, Erick
PPARα/γ-Targeting Amorfrutin Phytocannabinoids from Aerial Parts of Glycyrrhiza foetida
2023 Serino, E.; Iannotti, F. A.; Al-Hmadi, H. B.; Caprioglio, D.; Moriello, C.; Masi, F.; Hammami, S.; Appendino, G.; Vitale, R. M.; Taglialatela-Scafati, O.
2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play
2022 Infantino, R; Boccella, S; Scuteri, D; Perrone, M; Ricciardi, F; M Vitale, R; Bonsale, R; Parente, A; Allocca, I; Virtuoso, A; De Luca, C; Belardo, C; Amodeo, P; Gentile, V; Cirillo, G; Bagetta, G; Luongo, L; Maione, S; Guida, F
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors
2021 Boccella, Serena; Guida, Francesca; Iannotta, Monica; Iannotti, Fabio Arturo; Infantino, Rosmara; Ricciardi, Flavia; Cristiano, Claudia; Vitale, Rosa Maria; Amodeo, Pietro; Marabese, Ida; Belardo, Carmela; de Novellis, Vito; Paino, Salvatore; Palazzo, Enza; Calignano, Antonio; Di Marzo, Vincenzo; Maione, Sabatino; Luongo, Livio
Beneficial effects of akkermansia muciniphila are not associated with major changes in the circulating endocannabinoidome but linked to higher mono-palmitoyl-glycerol levels as new pparα agonists
2021 Depommier, C.; Vitale, R. M.; Iannotti, F. A.; Silvestri, C.; Flamand, N.; Druart, C.; Everard, A.; Pelicaen, R.; Maiter, D.; Thissen, J. -P.; Loumaye, A.; Hermans, M. P.; Delzenne, N. M.; de Vos, W. M.; Di Marzo, V.; Cani, P. D.
Biosynthesis of the novel endogenous 15-lipoxygenase metabolites N-13-hydroxy-octodecadienoyl-ethanolamine and 13-hydroxy-octodecadienoyl-glycerol by human neutrophils and Eosinophils
2021 Archambault, As; Tinto, F; Dumais, E; Rakotoarivelo, V; Kostrzewa, M; Plante, Pl; Martin, C; Simard, M; Silvestri, C; Pouliot, R; Laviolette, M; Boulet, Lp; Vitale, Rm; Ligresti, A; Di Marzo, V; Flamand, N
Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation
2021 Vitale, Rm; Iannotti, Fa; Moriello, As; Tunisi, L; Piscitelli, F; Savopoulos, R; Cristino, L; De Petrocellis, L; Amodeo, P; Gray, R; Di Marzo, V
N-palmitoyl-d-glucosamine, a natural monosaccharide-based glycolipid, inhibits tlr4 and prevents lps-induced inflammation and neuropathic pain in mice
2021 Iannotta M.; Belardo C.; Trotta M.C.; Iannotti F.A.; Vitale R.M.; Maisto R.; Boccella S.; Infantino R.; Ricciardi F.; Mirto B.F.; Ferraraccio F.; Panarese I.; Amodeo P.; Tunisi L.; Cristino L.; D'amico M.; Di Marzo V.; Luongo L.; Maione S.; Guida F.
The (Poly)pharmacology of cannabidiol in neurological and neuropsychiatric disorders: Molecular mechanisms and targets
2021 Vitale, Rm; Iannotti, Fa; Amodeo, P
The combined effect of branching and elongation on the bioactivity profile of phytocannabinoids. Part i: Thermo-trps
2021 Mattoteia, D; Moriello, As; Taglialatelascafati, O; Amodeo, P; De Petrocellis, L; Appendino, G; Vitale, Rm; Caprioglio, D
The endocannabinoid system and ppars: Focus on their signalling crosstalk, action and transcriptional regulation
2021 Iannotti, Fa; Vitale, Rm
Cannabitwinol, a Dimeric Phytocannabinoid from Hemp, Cannabis sativa L., Is a Selective Thermo-TRP Modulator
2020 Chianese, Giuseppina; Lopatriello, Annalisa; Schianomoriello, Aniello; Caprioglio, Diego; Mattoteia, Daiana; Benetti, Emanuele; Ciceri, Daniele; Arnoldi, Lolita; De Combarieu, Eric; Vitale Rosa, M; Amodeo, Pietro; Appendino, Giovanni; DE PETROCELLIS, Luciano; Taglialatelascafati, Orazio
Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes
2020 Mazzotta, Sarah; Carullo, Gabriele; Schiano Moriello, Aniello; Amodeo, Pietro; DI MARZO, Vincenzo; Vegaholm, Margarita; Vitale, ROSA MARIA; Aiello, Francesca; Brizzi, Antonella; DE PETROCELLIS, Luciano
Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides
2020 Vitale, Rm; Avonto, C; Del Prete, D; Moriello, As; Amodeo, P; Appendino, G; De Petrocellis, L
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Eukaryotic Initiation Translation Factor 2A activation by cannabidiolic acid alters the protein homeostasis balance in glioblastoma cells | 1-gen-2024 | Bellone, Maria Laura; Syed, Azmal Ali; Vitale, Rosa Maria; Sigismondo, Gianluca; Mensitieri, Francesca; Pollastro, Federica; Amodeo, Pietro; Appendino, Giovanni; De Tommasi, Nunziatina; Krijgsveld, Jeroen; Piaz, Fabrizio Dal | |
| Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists | 1-gen-2024 | Kosar, Miroslav; Sarott, Roman C.; Sykes, David A.; Viray, Alexander E. G.; Vitale, Rosa Maria; Tomašević, Nataša; Li, Xiaoting; Ganzoni, Rudolf L. Z.; Kicin, Bilal; Reichert, Lisa; Patej, Kacper J.; Gómez-Bouzó, Uxía; Guba, Wolfgang; Mccormick, Peter J.; Hua, Tian; Gruber, Christian W.; Veprintsev, Dmitry B.; Frank, James A.; Grether, Uwe; Carreira, Erick M. | |
| Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE‐1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Studies | 1-gen-2024 | Vitale, ROSA MARIA; Maria Morace, Andrea; D'Errico, Antonio; Ricciardi, Federica; Fusco, Antimo; Boccella, Serena; Guida, Francesca; Nasso, Rosarita; Rading, Sebastian; Karsak, Meliha; Caprioglio, Diego; Iannotti, FABIO ARTURO; Arcone, Rosaria; Luongo, Livio; Masullo, Mariorosario; Maione, Sabatino; Amodeo, Pietro | |
| Phytochemical Characterization and TRPA1/TRPM8 Modulation Profile of the Cannabigerol-Rich Cannabis sativa L. Chemotype IV | 1-gen-2024 | Gargiulo, Ernesto; Moriello, Aniello Schiano; Benetti, Emanuele; Pagni, Luca; Arnoldi, Lolita; De Petrocellis, Luciano; Chianese, Giuseppina; Vitale, Rosa Maria; Taglialatela-Scafati, Orazio | |
| Editorial: "Small molecules targeting transmembrane receptors and ion channels in drug discovery" | 1-gen-2023 | Vitale, ROSA MARIA; Iannotti, FABIO ARTURO; Florio, Tullio | |
| Marine Natural and Nature-Inspired Compounds Targeting Peroxisome Proliferator Activated Receptors (PPARs) | 1-gen-2023 | D'Aniello, Enrico; Amodeo, Pietro; Vitale, ROSA MARIA | |
| Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells | 1-gen-2023 | Kosar, Miroslav; A Sykes, David; G Viray, Alexander E; Vitale, ROSA MARIA; C Sarott, Roman; L Ganzoni, Rudolf; Onion, David; M Tobias, Janelle; Leippe, Philipp; Ullmer, Christoph; A Zirwes, Elisabeth; Guba, Wolfgang; Grether, Uwe; A Frank, James; B Veprintsev, Dmitry; M Carreira, Erick | |
| PPARα/γ-Targeting Amorfrutin Phytocannabinoids from Aerial Parts of Glycyrrhiza foetida | 1-gen-2023 | Serino, E.; Iannotti, F. A.; Al-Hmadi, H. B.; Caprioglio, D.; Moriello, C.; Masi, F.; Hammami, S.; Appendino, G.; Vitale, R. M.; Taglialatela-Scafati, O. | |
| 2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play | 1-gen-2022 | Infantino, R; Boccella, S; Scuteri, D; Perrone, M; Ricciardi, F; M Vitale, R; Bonsale, R; Parente, A; Allocca, I; Virtuoso, A; De Luca, C; Belardo, C; Amodeo, P; Gentile, V; Cirillo, G; Bagetta, G; Luongo, L; Maione, S; Guida, F | |
| 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors | 1-gen-2021 | Boccella, Serena; Guida, Francesca; Iannotta, Monica; Iannotti, Fabio Arturo; Infantino, Rosmara; Ricciardi, Flavia; Cristiano, Claudia; Vitale, Rosa Maria; Amodeo, Pietro; Marabese, Ida; Belardo, Carmela; de Novellis, Vito; Paino, Salvatore; Palazzo, Enza; Calignano, Antonio; Di Marzo, Vincenzo; Maione, Sabatino; Luongo, Livio | |
| Beneficial effects of akkermansia muciniphila are not associated with major changes in the circulating endocannabinoidome but linked to higher mono-palmitoyl-glycerol levels as new pparα agonists | 1-gen-2021 | Depommier, C.; Vitale, R. M.; Iannotti, F. A.; Silvestri, C.; Flamand, N.; Druart, C.; Everard, A.; Pelicaen, R.; Maiter, D.; Thissen, J. -P.; Loumaye, A.; Hermans, M. P.; Delzenne, N. M.; de Vos, W. M.; Di Marzo, V.; Cani, P. D. | |
| Biosynthesis of the novel endogenous 15-lipoxygenase metabolites N-13-hydroxy-octodecadienoyl-ethanolamine and 13-hydroxy-octodecadienoyl-glycerol by human neutrophils and Eosinophils | 1-gen-2021 | Archambault, As; Tinto, F; Dumais, E; Rakotoarivelo, V; Kostrzewa, M; Plante, Pl; Martin, C; Simard, M; Silvestri, C; Pouliot, R; Laviolette, M; Boulet, Lp; Vitale, Rm; Ligresti, A; Di Marzo, V; Flamand, N | |
| Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation | 1-gen-2021 | Vitale, Rm; Iannotti, Fa; Moriello, As; Tunisi, L; Piscitelli, F; Savopoulos, R; Cristino, L; De Petrocellis, L; Amodeo, P; Gray, R; Di Marzo, V | |
| N-palmitoyl-d-glucosamine, a natural monosaccharide-based glycolipid, inhibits tlr4 and prevents lps-induced inflammation and neuropathic pain in mice | 1-gen-2021 | Iannotta M.; Belardo C.; Trotta M.C.; Iannotti F.A.; Vitale R.M.; Maisto R.; Boccella S.; Infantino R.; Ricciardi F.; Mirto B.F.; Ferraraccio F.; Panarese I.; Amodeo P.; Tunisi L.; Cristino L.; D'amico M.; Di Marzo V.; Luongo L.; Maione S.; Guida F. | |
| The (Poly)pharmacology of cannabidiol in neurological and neuropsychiatric disorders: Molecular mechanisms and targets | 1-gen-2021 | Vitale, Rm; Iannotti, Fa; Amodeo, P | |
| The combined effect of branching and elongation on the bioactivity profile of phytocannabinoids. Part i: Thermo-trps | 1-gen-2021 | Mattoteia, D; Moriello, As; Taglialatelascafati, O; Amodeo, P; De Petrocellis, L; Appendino, G; Vitale, Rm; Caprioglio, D | |
| The endocannabinoid system and ppars: Focus on their signalling crosstalk, action and transcriptional regulation | 1-gen-2021 | Iannotti, Fa; Vitale, Rm | |
| Cannabitwinol, a Dimeric Phytocannabinoid from Hemp, Cannabis sativa L., Is a Selective Thermo-TRP Modulator | 1-gen-2020 | Chianese, Giuseppina; Lopatriello, Annalisa; Schianomoriello, Aniello; Caprioglio, Diego; Mattoteia, Daiana; Benetti, Emanuele; Ciceri, Daniele; Arnoldi, Lolita; De Combarieu, Eric; Vitale Rosa, M; Amodeo, Pietro; Appendino, Giovanni; DE PETROCELLIS, Luciano; Taglialatelascafati, Orazio | |
| Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes | 1-gen-2020 | Mazzotta, Sarah; Carullo, Gabriele; Schiano Moriello, Aniello; Amodeo, Pietro; DI MARZO, Vincenzo; Vegaholm, Margarita; Vitale, ROSA MARIA; Aiello, Francesca; Brizzi, Antonella; DE PETROCELLIS, Luciano | |
| Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides | 1-gen-2020 | Vitale, Rm; Avonto, C; Del Prete, D; Moriello, As; Amodeo, P; Appendino, G; De Petrocellis, L |