DI FIORE, ANNA
DI FIORE, ANNA
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity
2006 M. P. Leese; B. LeBlond; S. P. Newman; A. Di Fiore; G. De Simone; C. T. Supuran; A. Purohit; M. J. Reed; B. V. L. Potter.
Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography.
2008 Woo, Lw; Fischer, Ds; Sharland, Cm; Trusselle, M; Foster, Pa; Chander, Sk; Di Fiore, A; Supuran, Ct; De Simone, G; Purohit, A; Reed, Mj; Potter, Bv
Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs?
2008 De Simone G; Di Fiore A; Supuran CT.
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition
2016 Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves
Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis
2020 Urbanski, Linda J.; Di Fiore, Anna; Azizi, Latifeh; Hytonen, Vesa P.; Kuuslahti, Marianne; Buonanno, Martina; Monti, Simona M.; Angeli, Andrea; Emameh, Reza Zolfaghari; Supuran, Claudiu T.; De Simone, Giuseppina; Parkkila, Seppo
Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes.
2008 Hilvo, M; Baranauskiene, L; Salzano, Am; Scaloni, A; Matulis, D; Innocenti, A; Scozzafava, A; Monti, Sm; Di Fiore, A; De Simone, G; Lindfors, M; Jänis, J; Valjakka, J; Pastoreková, S; Pastorek, J; Kulomaa, Ms; Nordlund, Hr; Supuran, Ct; Parkkila, S
Biochemical, structural, and computational studies of a ?-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei
2022 Di Fiore A.; De Luca V.; Langella E.; Nocentini A.; Buonanno M.; Monti S.M.; Supuran C.T.; Capasso C.; De Simone G.
Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity
2008 Supuran, Ct; Di Fiore, A; De Simone, G
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.
2010 Di Fiore, A; Monti, Sm; Innocenti, A; Winum, Jy; De Simone, G; Supuran, Ct
Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX
2006 DE SIMONE, Giuseppina; Vitale, ROSA MARIA; DI FIORE, Anna; Pedone, Carlo; Scozzafava, Andrea; Montero, Jeanlouis; Winum, Jeanyves; Supuran Claudiu, T
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors.
2008 Di Fiore, A; Pedone, C; Antel, J; Waldeck, H; Witte, A; Wurl, M; Scozzafava, A; Supuran, Ct; De Simone, G
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
2006 DI FIORE, Anna; Pedone, Carlo; D'Ambrosio, Katia; Scozzafava, Andrea; DE SIMONE, Giuseppina; Supuran Claudiu, T
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II
2005 DI FIORE, Anna; DE SIMONE, Giuseppina; Menchise, Valeria; Pedone, Carlo; Casini, Angela; Scozzafava, Andrea; Supuran Claudiu, T
CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II
2006 Menchise, V; DE SIMONE, Giuseppina; DI FIORE, Anna; Scozzafava, A; T Supuran, C
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors
2012 Truppo, E; Supuran, Ct; Sandomenico, A; Vullo, D; Innocenti, A; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm
Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II
2011 Di Fiore, A; Maresca, A; Alterio, V; Supuran, Ct; De Simone, G
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide.
2010 Dathan, NINA ALAYNE; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; DI FIORE, Anna
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.
2009 Alterio, V; Hilvo, M; Di Fiore, A; Supuran, Ct; Pan, P; Parkkila, S; Scaloni, A; Pastorek, J; Pastorekova, S; Pedone, C; Scozzafava, A; Monti, Sm; De Simone, G
Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense
2015 De Simone, G; Monti, Sm; Alterio, V; Buonanno, M; De Luca, V; Rossi, M; Carginale, V; Supuran, Ct; Capasso, C; Di Fiore, A
Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements.
2017 Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity | 1-gen-2006 | M. P. Leese; B. LeBlond; S. P. Newman; A. Di Fiore; G. De Simone; C. T. Supuran; A. Purohit; M. J. Reed; B. V. L. Potter. | |
| Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. | 1-gen-2008 | Woo, Lw; Fischer, Ds; Sharland, Cm; Trusselle, M; Foster, Pa; Chander, Sk; Di Fiore, A; Supuran, Ct; De Simone, G; Purohit, A; Reed, Mj; Potter, Bv | |
| Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? | 1-gen-2008 | De Simone G; Di Fiore A; Supuran CT. | |
| Benzoxaborole as a new chemotype for carbonic anhydrase inhibition | 1-gen-2016 | Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves | |
| Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis | 1-gen-2020 | Urbanski, Linda J.; Di Fiore, Anna; Azizi, Latifeh; Hytonen, Vesa P.; Kuuslahti, Marianne; Buonanno, Martina; Monti, Simona M.; Angeli, Andrea; Emameh, Reza Zolfaghari; Supuran, Claudiu T.; De Simone, Giuseppina; Parkkila, Seppo | |
| Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes. | 1-gen-2008 | Hilvo, M; Baranauskiene, L; Salzano, Am; Scaloni, A; Matulis, D; Innocenti, A; Scozzafava, A; Monti, Sm; Di Fiore, A; De Simone, G; Lindfors, M; Jänis, J; Valjakka, J; Pastoreková, S; Pastorek, J; Kulomaa, Ms; Nordlund, Hr; Supuran, Ct; Parkkila, S | |
| Biochemical, structural, and computational studies of a ?-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei | 1-gen-2022 | Di Fiore A.; De Luca V.; Langella E.; Nocentini A.; Buonanno M.; Monti S.M.; Supuran C.T.; Capasso C.; De Simone G. | |
| Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity | 1-gen-2008 | Supuran, Ct; Di Fiore, A; De Simone, G | |
| Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. | 1-gen-2010 | Di Fiore, A; Monti, Sm; Innocenti, A; Winum, Jy; De Simone, G; Supuran, Ct | |
| Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX | 1-gen-2006 | DE SIMONE, Giuseppina; Vitale, ROSA MARIA; DI FIORE, Anna; Pedone, Carlo; Scozzafava, Andrea; Montero, Jeanlouis; Winum, Jeanyves; Supuran Claudiu, T | |
| Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors. | 1-gen-2008 | Di Fiore, A; Pedone, C; Antel, J; Waldeck, H; Witte, A; Wurl, M; Scozzafava, A; Supuran, Ct; De Simone, G | |
| Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. | 1-gen-2006 | DI FIORE, Anna; Pedone, Carlo; D'Ambrosio, Katia; Scozzafava, Andrea; DE SIMONE, Giuseppina; Supuran Claudiu, T | |
| Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II | 1-gen-2005 | DI FIORE, Anna; DE SIMONE, Giuseppina; Menchise, Valeria; Pedone, Carlo; Casini, Angela; Scozzafava, Andrea; Supuran Claudiu, T | |
| CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II | 1-gen-2006 | Menchise, V; DE SIMONE, Giuseppina; DI FIORE, Anna; Scozzafava, A; T Supuran, C | |
| Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors | 1-gen-2012 | Truppo, E; Supuran, Ct; Sandomenico, A; Vullo, D; Innocenti, A; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm | |
| Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II | 1-gen-2011 | Di Fiore, A; Maresca, A; Alterio, V; Supuran, Ct; De Simone, G | |
| Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. | 1-gen-2010 | Dathan, NINA ALAYNE; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; DI FIORE, Anna | |
| Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. | 1-gen-2009 | Alterio, V; Hilvo, M; Di Fiore, A; Supuran, Ct; Pan, P; Parkkila, S; Scaloni, A; Pastorek, J; Pastorekova, S; Pedone, C; Scozzafava, A; Monti, Sm; De Simone, G | |
| Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense | 1-gen-2015 | De Simone, G; Monti, Sm; Alterio, V; Buonanno, M; De Luca, V; Rossi, M; Carginale, V; Supuran, Ct; Capasso, C; Di Fiore, A | |
| Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements. | 1-gen-2017 | Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G |