COLOMBO, GIANCARLO
COLOMBO, GIANCARLO
Istituto di Neuroscienze - IN -
Delving into the reducing effects of the GABAB positive allosteric modulator, KK-92A, on alcohol-related behaviors in rats
2023 Paola Maccioni; Katarzyna Kaczanowska; Carla Lobina; Laura Regonini Somenzi; Valentina Bassareo; Gian Luigi Gessa; Harshani R Lawrence; Patricia McDonald; Giancarlo Colombo
Exposure to an enriched environment exerts anxiolytic effects in Sardinian alcohol-preferring rats
2023 Lobina, Carla; Maccioni, Paola; Luigi Gessa, Gian; Colombo, Giancarlo
Reducing effect of intragastrically administered saikosaponin A on alcohol and sucrose self-administration in rats
2023 Maccioni, Paola; Chin, YoungWon; Corelli, Federico; Kwon, Hak Cheol; Colombo, Giancarlo
Analgesic effects of saikosaponin A in a rat model of chronic inflammatory pain
2022 Lobina C.; Lee J.H.; Pel P.; Chin Y.W.; Kwon H.C.; Colombo G.
Blockade of the GABAB receptor suppressed alcohol self-administration in rats: An effect similar to that produced by GABAB receptor activation
2022 Maccioni, P; Lorrai, I; Carai, Mam; Gessa, Gl; Colombo, G
Development of partial tolerance to the suppressing effect of the positive allosteric modulator of the GABAB receptor, KK-92A, on alcohol self-administration in rats
2022 Maccioni, Paola; Kaczanowska, Katarzyna; Mcdonald, Patricia; Colombo, Giancarlo
Development of tolerance upon repeated administration with the GABAB receptor positive allosteric modulator, COR659, on alcohol drinking in rodents
2022 Lorrai, I; Shankula, C; Marquez Gaytan, J; Maccioni, R; Lobina, C; Maccioni, P; Brizzi, A; Mugnaini, C; Gessa, Gl; Sanna, Pp; Corelli, F; Colombo, G
Environmental enrichment augments binge-like alcohol drinking in Sardinian alcohol-preferring rats
2022 Maccioni, Paola; Regoninisomenzi, Laura; Lobina, Carla; M Carai, Mauro A; Luigi Gessa, Gian; Colombo, Giancarlo
Exposure to an enriched environment reduces alcohol self-administration in Sardinian alcohol-preferring rats
2022 Maccioni P.; Bratzu J.; Lobina C.; Acciaro C.; Corrias G.; Capra A.; Carai M.A.M.; Agabio R.; Muntoni A.L.; Gessa G.L.; Colombo G.
Reducing Effect of Cannabidiol on Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats
2022 Maccioni, P; Bratzu, J; Carai, Mam; Colombo, G; Gessa, Gl
Reducing effect of the novel positive allosteric modulator of the GABA B receptor, COR659, on binge-like alcohol drinking in male mice and rats
2022 Lorrai, I.; Shankula, C.; Gaytan, J.M.; Kawamura, T.; Maccioni, P.; Mugnaini, C.; Corelli, F.; Gessa, G.L.; Sanna, P.P.; Colombo G.
Suppressing effect of a saikosaponin-enriched extract of Bupleurum falcatum on alcohol and chocolate self-administration in rats
2022 Maccioni, P; Colombo, G; Lorrai, I; Lee, Jh; Pel, P; Chin, Yw; Kwon, Hc
Analgesic properties of a food grade lecithin delivery system of Zingiber officinale and Acmella oleracea standardized extracts in rats
2021 Lobina C.; Sau R.; Fara F.; Maccioni P.; Carai M.A.M.; Colombo G.
Role of inflammation in alcohol-related brain abnormalities: a translational study.
2021 Anastasia, Lanquetin; Sophie, Leclercq; de Timary Philippe, ; Shailendra, Segobin; Mikaël, Naveau; Laurent, Coulbault; Maccioni, Paola; Lorrai, Irene; Colombo, Giancarlo; Denis, Vivien; Marina, Rubio; Annelise, Pitel
Suppressing effect of the novel positive allosteric modulator of the GABA(B) receptor, COR659, on locomotor hyperactivity induced by different drugs of abuse
2021 Lobina, Carla; Maccioni, Paola; Lorrai, Irene; Zaru, Alessandro; Collu, Maria; Carai, Mauro A. M.; Brizzi, Antonella; Mugnaini, Claudia; Gessa, Gian Luigi; Corelli, Federico; Colombo, Giancarlo
The effect of telmisartan, an angiotensin receptor blocker, on alcohol consumption and alcohol-induced dopamine release in the nucleus accumbens
2021 Tezcan, K; Yananli, Hr; Demirkapu, Mj; Goren, Mz; Sakalli, He; Colombo, G; Gulhan, R
The Novel Positive Allosteric Modulator of the GABA B Receptor, KK-92A, Suppresses Alcohol Self-Administration and Cue-Induced Reinstatement of Alcohol Seeking in Rats
2021 Maccioni, Paola; Kaczanowska, Katarzyna; Lawrence, Harshani; Yunsang, ; Bratzu Jessica, Bratzu; Gessa, GIAN LUIGI; Mcdonald, Patricia; Colombo, Giancarlo
Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo
2020 Mugnaini C.; Kostrzewa M.; Bryk M.; Mahmoud A.M.; Brizzi A.; Lamponi S.; Giorgi G.; Ferlenghi F.; Vacondio F.; Maccioni P.; Colombo G.; Mor M.; Starowicz K.; Di Marzo V.; Ligresti A.; Corelli F.
Differential Effects of Saikosaponins A, B-2, B-4, C and D on Alcohol and Chocolate Self-Administration in Rats
2020 Maccioni, Paola; Lorrai, Irene; Fara, Federica; Carai, Mauro A. M.; Gessa, Gian Luigi; Chin, YoungWon; Lee, Jung Hwan; Kwon, Hak Cheol; Corelli, Federico; Colombo, Giancarlo
The GABAB receptor positive allosteric modulator COR659: In vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives
2020 Ferlenghi, F; Maccioni, P; Mugnaini, C; Brizzi, A; Fara, F; Mostallino, R; Maccioni, Paola; Colombo, G; Mor, M; Vacondio, F; Corelli, F
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Delving into the reducing effects of the GABAB positive allosteric modulator, KK-92A, on alcohol-related behaviors in rats | 1-gen-2023 | Paola Maccioni; Katarzyna Kaczanowska; Carla Lobina; Laura Regonini Somenzi; Valentina Bassareo; Gian Luigi Gessa; Harshani R Lawrence; Patricia McDonald; Giancarlo Colombo | |
| Exposure to an enriched environment exerts anxiolytic effects in Sardinian alcohol-preferring rats | 1-gen-2023 | Lobina, Carla; Maccioni, Paola; Luigi Gessa, Gian; Colombo, Giancarlo | |
| Reducing effect of intragastrically administered saikosaponin A on alcohol and sucrose self-administration in rats | 1-gen-2023 | Maccioni, Paola; Chin, YoungWon; Corelli, Federico; Kwon, Hak Cheol; Colombo, Giancarlo | |
| Analgesic effects of saikosaponin A in a rat model of chronic inflammatory pain | 1-gen-2022 | Lobina C.; Lee J.H.; Pel P.; Chin Y.W.; Kwon H.C.; Colombo G. | |
| Blockade of the GABAB receptor suppressed alcohol self-administration in rats: An effect similar to that produced by GABAB receptor activation | 1-gen-2022 | Maccioni, P; Lorrai, I; Carai, Mam; Gessa, Gl; Colombo, G | |
| Development of partial tolerance to the suppressing effect of the positive allosteric modulator of the GABAB receptor, KK-92A, on alcohol self-administration in rats | 1-gen-2022 | Maccioni, Paola; Kaczanowska, Katarzyna; Mcdonald, Patricia; Colombo, Giancarlo | |
| Development of tolerance upon repeated administration with the GABAB receptor positive allosteric modulator, COR659, on alcohol drinking in rodents | 1-gen-2022 | Lorrai, I; Shankula, C; Marquez Gaytan, J; Maccioni, R; Lobina, C; Maccioni, P; Brizzi, A; Mugnaini, C; Gessa, Gl; Sanna, Pp; Corelli, F; Colombo, G | |
| Environmental enrichment augments binge-like alcohol drinking in Sardinian alcohol-preferring rats | 1-gen-2022 | Maccioni, Paola; Regoninisomenzi, Laura; Lobina, Carla; M Carai, Mauro A; Luigi Gessa, Gian; Colombo, Giancarlo | |
| Exposure to an enriched environment reduces alcohol self-administration in Sardinian alcohol-preferring rats | 1-gen-2022 | Maccioni P.; Bratzu J.; Lobina C.; Acciaro C.; Corrias G.; Capra A.; Carai M.A.M.; Agabio R.; Muntoni A.L.; Gessa G.L.; Colombo G. | |
| Reducing Effect of Cannabidiol on Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats | 1-gen-2022 | Maccioni, P; Bratzu, J; Carai, Mam; Colombo, G; Gessa, Gl | |
| Reducing effect of the novel positive allosteric modulator of the GABA B receptor, COR659, on binge-like alcohol drinking in male mice and rats | 1-gen-2022 | Lorrai, I.; Shankula, C.; Gaytan, J.M.; Kawamura, T.; Maccioni, P.; Mugnaini, C.; Corelli, F.; Gessa, G.L.; Sanna, P.P.; Colombo G. | |
| Suppressing effect of a saikosaponin-enriched extract of Bupleurum falcatum on alcohol and chocolate self-administration in rats | 1-gen-2022 | Maccioni, P; Colombo, G; Lorrai, I; Lee, Jh; Pel, P; Chin, Yw; Kwon, Hc | |
| Analgesic properties of a food grade lecithin delivery system of Zingiber officinale and Acmella oleracea standardized extracts in rats | 1-gen-2021 | Lobina C.; Sau R.; Fara F.; Maccioni P.; Carai M.A.M.; Colombo G. | |
| Role of inflammation in alcohol-related brain abnormalities: a translational study. | 1-gen-2021 | Anastasia, Lanquetin; Sophie, Leclercq; de Timary Philippe, ; Shailendra, Segobin; Mikaël, Naveau; Laurent, Coulbault; Maccioni, Paola; Lorrai, Irene; Colombo, Giancarlo; Denis, Vivien; Marina, Rubio; Annelise, Pitel | |
| Suppressing effect of the novel positive allosteric modulator of the GABA(B) receptor, COR659, on locomotor hyperactivity induced by different drugs of abuse | 1-gen-2021 | Lobina, Carla; Maccioni, Paola; Lorrai, Irene; Zaru, Alessandro; Collu, Maria; Carai, Mauro A. M.; Brizzi, Antonella; Mugnaini, Claudia; Gessa, Gian Luigi; Corelli, Federico; Colombo, Giancarlo | |
| The effect of telmisartan, an angiotensin receptor blocker, on alcohol consumption and alcohol-induced dopamine release in the nucleus accumbens | 1-gen-2021 | Tezcan, K; Yananli, Hr; Demirkapu, Mj; Goren, Mz; Sakalli, He; Colombo, G; Gulhan, R | |
| The Novel Positive Allosteric Modulator of the GABA B Receptor, KK-92A, Suppresses Alcohol Self-Administration and Cue-Induced Reinstatement of Alcohol Seeking in Rats | 1-gen-2021 | Maccioni, Paola; Kaczanowska, Katarzyna; Lawrence, Harshani; Yunsang, ; Bratzu Jessica, Bratzu; Gessa, GIAN LUIGI; Mcdonald, Patricia; Colombo, Giancarlo | |
| Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo | 1-gen-2020 | Mugnaini C.; Kostrzewa M.; Bryk M.; Mahmoud A.M.; Brizzi A.; Lamponi S.; Giorgi G.; Ferlenghi F.; Vacondio F.; Maccioni P.; Colombo G.; Mor M.; Starowicz K.; Di Marzo V.; Ligresti A.; Corelli F. | |
| Differential Effects of Saikosaponins A, B-2, B-4, C and D on Alcohol and Chocolate Self-Administration in Rats | 1-gen-2020 | Maccioni, Paola; Lorrai, Irene; Fara, Federica; Carai, Mauro A. M.; Gessa, Gian Luigi; Chin, YoungWon; Lee, Jung Hwan; Kwon, Hak Cheol; Corelli, Federico; Colombo, Giancarlo | |
| The GABAB receptor positive allosteric modulator COR659: In vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives | 1-gen-2020 | Ferlenghi, F; Maccioni, P; Mugnaini, C; Brizzi, A; Fara, F; Mostallino, R; Maccioni, Paola; Colombo, G; Mor, M; Vacondio, F; Corelli, F |