The Genes-to-Systems Breast Cancer (G2SBC) Database is a bioinformatics resource that collects and integrates data about genes, transcripts and proteins which have been reported in literature to be altered in breast cancer cells. Moreover, the resource includes a section dedicated to mathematical models related to cancerogenesis, tumour growth and tumour response to treatments. The G2SBC Database is a multilevel resource dedicated to the molecular and systems biology of breast cancer, including both the building-blocks level (genes, transcripts and proteins) and the systems level (molecular and cellular systems, cell populations). Taking advantage from the multilevel approach and from a series of tools for the analysis of the database content, the G2SBC Database enables predictions which may induce new experiments.
The Genes-to-Systems Breast Cancer (G2SBC) Database
Ettore Mosca;Roberta Alfieri;Ivan Merelli;Federica Viti;Luciano Milanesi
2010
Abstract
The Genes-to-Systems Breast Cancer (G2SBC) Database is a bioinformatics resource that collects and integrates data about genes, transcripts and proteins which have been reported in literature to be altered in breast cancer cells. Moreover, the resource includes a section dedicated to mathematical models related to cancerogenesis, tumour growth and tumour response to treatments. The G2SBC Database is a multilevel resource dedicated to the molecular and systems biology of breast cancer, including both the building-blocks level (genes, transcripts and proteins) and the systems level (molecular and cellular systems, cell populations). Taking advantage from the multilevel approach and from a series of tools for the analysis of the database content, the G2SBC Database enables predictions which may induce new experiments.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


