SMARTool - Interim Progress Report 1

The work performed in the first six-month of the project life, has been strategically directed to achieve the first three scientific milestones of the project MS1.1, MS 2.1 and MS 2.3 (Month 18). The progress towards the achievement of these milestones passed through a devised and well-coordinated execution of tasks and sub-tasks under the relevant WPs, namely WP1 and WP2. The main and common objective of WP1 and WP2 to reach MS1.1-2.3 is the patient specific imaging (CCTA) and non-imaging (clinical, genetics and circulatory markers) data collection at two time points (retrospectivebaseline and prospective-follow up). During M1-M6 the Consortium discussed and agreed on: ? A unified clinical study protocol to be submitted for ethics application to center-specific Committees for follow up patient recruitment and data acquisition ? The eligibility criteria and the exclusion criteria (clinical and technical ones) for SMARTool study to be applied for selection to EVINCI cohort (515 patients collected in EVINCI study) ? Collection and organization of baseline imaging and non imaging data of the selected population ? Requirements and creation of an online Data entry platform for secure storage of patient information (baseline and follow up) and data sharing.