Clarkson disease: a rare syndrome for a first approach to the scientific research

the Systemic Capillary Leakage Syndrome is analyzed both deepening literature data analysis and resorting to new data. A five day period of weight oscillation, strongly present in the untreated patient, does appear, even if less precise in frequency and lower in amplitude, in the last two weeks of the recorded month for two healthy females living together, suggesting that SCLS may be the pathological amplification of a physiological behavior. A possible gender difference in the K or Lambda chains in the monoclonal Immunoglobuline expressed by patients could suggest where to narrow search for the still unknown pathological agent in the episodic serum