Nanoparticles with a biogenic surface Extracellular vesicles (EVs) are the universal shuttles of intercellular communication, transferring lipids, proteins and nucleic acids, mediating physiological processes and spreading various diseases, including cancer and infections. The main goal of the EU-funded BOW project is to explore and develop the technology capable of lending the biological surface precision, circulation and targeting abilities of EVs to superparamagnetic nanodevices by coating them with a single- or multi-layer EV membrane. This technology aims to advance implantable nanodevices and nanomaterials towards sustainable production and clinical translation, proving the possibility of recapitulating biomimetic functions on any synthetic nanodevice.
BOW - Biogenic Organotropic Wetsuits
Antonella Bongiovanni;Paolo Colombo;Daniele Romancino;Manno Mauro;Valle Francesco;Elia Di Schiavi;
2020
Abstract
Nanoparticles with a biogenic surface Extracellular vesicles (EVs) are the universal shuttles of intercellular communication, transferring lipids, proteins and nucleic acids, mediating physiological processes and spreading various diseases, including cancer and infections. The main goal of the EU-funded BOW project is to explore and develop the technology capable of lending the biological surface precision, circulation and targeting abilities of EVs to superparamagnetic nanodevices by coating them with a single- or multi-layer EV membrane. This technology aims to advance implantable nanodevices and nanomaterials towards sustainable production and clinical translation, proving the possibility of recapitulating biomimetic functions on any synthetic nanodevice.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.