Preclinical imaging has become a powerful tool in biomedical research, allowing the non-invasive detection of biomarkers of disease. It enables the collection of anatomical, functional and dynamic imaging data from living experimental animals, including genetically modified models. Preclinical imaging approaches provide the unique opportunity to perform longitudinal studies of the same animal, minimizing experimental variability and number of animals per study, refining preclinical research procedures in agreement with the 3Rs principles. Moreover, imaging represents a valuable translational tool between preclinical research and clinical trials.
PRECLINICAL IMAGING FACILITY-IBB website
Sara Gargiulo
2018
Abstract
Preclinical imaging has become a powerful tool in biomedical research, allowing the non-invasive detection of biomarkers of disease. It enables the collection of anatomical, functional and dynamic imaging data from living experimental animals, including genetically modified models. Preclinical imaging approaches provide the unique opportunity to perform longitudinal studies of the same animal, minimizing experimental variability and number of animals per study, refining preclinical research procedures in agreement with the 3Rs principles. Moreover, imaging represents a valuable translational tool between preclinical research and clinical trials.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
