Application of Spectroscopic Techniques to Metabolomic Research- Applied Sciences (MDPI)

Special Issue "Application of Spectroscopic Techniques to Metabolomic Research" Applied Sciences - MDPI Special Issue Information Dear Colleagues, Metabolomics is no longer an emerging technology; it is an established powerful approach that can be extended to a wide range of biological investigations. Even if the study of small molecules is more ancient than that of large bio-molecules, its application in terms of whole metabolome is quite recent. It is, in fact, the youngest amongst the "omics" tools. NMR- and MS-based metabolomics strategies allow for the contemporary analysis (both qualitative and quantitative) of the 'metabolic profile', including many metabolites (hundreds to thousands) within (at least in principle) any kind of biological specimens (bacteria, eukaryotic cells, tissues, biological fluids, culture medium, food, etc). The metabolome is the ultimate product of the cellular metabolism, reflecting the overall state of the studied cell/organism/ecosystem, and hence a metabolomic analysis of biological samples allows for the identification of a specific set of metabolites permitting their classification according to the levels of selected molecules expressed within the data. Therefore, the analysis can provide insights about the distinct pathways that are altered as a consequence (direct and/or indirect) of a specific disease/drug/chemical/environmental condition/stimulus/genetic background, etc. We would like to contribute this Special Issue to spread recent advances in the field. We encourage you to submit either papers concerning the novel application of the already assessed protocols (for the study of new biological systems, cellular models, etc.) or papers regarding the improvement of the protocols and/or the methodologies. Dr. Giuseppina Andreotti Dr. Debora Paris Guest Editors