We developed a library of single neuron models for rat CA1 hippocampal neurons. The model morphologies were based on three-dimensional morphological reconstructions obtained in a previous study. Electrophysiological features of interest were extracted from experimental traces using custom code exploiting the open source Electrophysiological Feature Extraction Library (eFEL). Extracted features were then used for multi-objective model parameter optimizations performed using the open source Blue Brain Python Optimization Library (BluePyOpt). Entries for the individual models are available in the EBRAINS repository. This dataset groups the code for all models, together with all outputs from the optimization process.

Optimization of single neuron models for CA1 hippocampal neurons in rat (v4.0.5)

Luca L. Bologna
Primo
Data Curation
;
Rosanna Migliore
Secondo
Formal Analysis
;
Carmen A. Lupascu
Penultimo
Data Curation
;
2024

Abstract

We developed a library of single neuron models for rat CA1 hippocampal neurons. The model morphologies were based on three-dimensional morphological reconstructions obtained in a previous study. Electrophysiological features of interest were extracted from experimental traces using custom code exploiting the open source Electrophysiological Feature Extraction Library (eFEL). Extracted features were then used for multi-objective model parameter optimizations performed using the open source Blue Brain Python Optimization Library (BluePyOpt). Entries for the individual models are available in the EBRAINS repository. This dataset groups the code for all models, together with all outputs from the optimization process.
2024
Istituto di Biofisica - IBF - Sede Secondaria Palermo
rat, hippocampus, computational models
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/538536
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