CLEMENTI, FRANCESCO
CLEMENTI, FRANCESCO
Istituto di Neuroscienze - IN -
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based alpha7- and alpha9-nicotinic ligands on glioblastoma cells
2022 Pucci S.; Bolchi C.; Bavo F.; Pallavicini M.; De Palma C.; Renzi M.; Fucile S.; Benfante R.; Di Lascio S.; Lattuada D.; Bessereau J.L.; D'Alessandro M.; Risson V.; Zoli M.; Clementi F.; Gotti C.
Choline and nicotine increase glioblastoma cell proliferation by binding and activating alpha 7-and alpha 9-containing nicotinic receptors
2021 Pucci, Susanna; Fasoli, Francesca; Moretti, Milena; Benfante, Roberta; Di Lascio, Simona; Viani, Paola; Daga, Antonio; Gordon Thomas, J; Mcintosh, Michael; Zoli, Michele; Clementi, Francesco; Gotti, Cecilia
Persistent cognitive and affective alterations at late withdrawal stages after long-term intermittent exposure to tobacco smoke or electronic cigarette vapour: Behavioural changes and their neurochemical correlates
2020 Ponzoni, Luisa; Braida, Daniela; Carboni, Lucia; Moretti, Milena; Viani, Paola; Clementi, Francesco; Zoli, Michele; Gotti, Cecilia; Sala, Mariaelvina
Increased sensitivity to Delta(9)-THC-induced rewarding effects after seven-week exposure to electronic and tobacco cigarettes in mice
2019 Ponzoni, L.; Moretti, M.; Braida, D.; Zoli, M.; Clementi, F.; Viani, P.; Sala, M.; Gotti, C.
alfa9- and alfa7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line
2018 Mucchietto, V; Fasoli, F; Pucci, S; Moretti, M; Benfante, R; Maroli, A; Di Lascio, S; Bolchi, C; Pallavicini, M; Dowell, C; Mcintosh, M; Clementi, F; Gotti, C
Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an alpha 7-nAChR, alpha 9-nAChR Antagonist and of a Pro-Oxidant Mitocan
2018 Bavo, Francesco; Pucci, Susanna; Fasoli, Francesca; Lammi, Carmen; Moretti, Milena; Mucchietto, Vanessa; Lattuada, Donatella; Viani, Paola; De Palma, Clara; Budriesi, Roberta; Corradini, Irene; Dowell, Cheryl; Mcintosh, J Michael; Clementi, Francesco; Bolchi, Cristiano; Gotti, Cecilia; Pallavicini, Marco
In vivo chronic nicotine exposure differentially and reversibly affects upregulation and stoichiometry of ?4?2 nicotinic receptors in cortex and thalamus
2016 Fasoli, F; Moretti, M; Zoli, M; Pistillo, F; Crespi, A; Clementi, F; Mc ClureBegley, T; Marks, Mj; Gotti, C
Neuronal acetylcholine nicotinic receptors as new targets for lung cancer treatment
2016 Mucchietto, V; Crespi, A; Fasoli, F; Clementi, F; Gotti, C
Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice
2015 Ponzoni, L; Moretti, M; Sala, M; Fasoli, F; Mucchietto, V; Lucini, V; Cannazza, G; Gallesi, G; Castellana, Cn; Clementi, F; Zoli, M; Gotti, C; Braida, D
Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: Focus on nicotine effects
2015 Pistillo, F.; Clementi, F.; Zoli, M.; Gotti, C.
The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors
2014 Ponzoni, L; Braida, D; Pucci, L; Andrea, D; Fasoli, F; Manfredi, I; Papke, Rl; Stokes, C; Cannazza, G; Clementi, F; Gotti, C; Sala, M
CC4, a dimer of cytisine, is a selective partial agonist at alpha4beta2/alpha6beta2 nAChR with improved selectivity for tobacco smoking cessation
2013 Sala, Mariaelvina; Braida, Daniela; Pucci, Luca; Manfredi, Irene; J Marks, Michael; R Wageman, Charles; R Grady, Sharon; Loi, Barbara; Fucile, Sergio; Fasoli, Francesca; Zoli, Michele; Tasso, Bruno; Sparatore, Fabio; Clementi, Francesco; Gotti, Cecilia
Nicotine-modulated subunit stoichiometry affects stability and trafficking of alpha3beta4 nicotinic receptor
2013 Mazzo, Francesca; Pistillo, Francesco; Grazioso, Giovanni; Clementi, Francesco; Borgese, Nica; Gotti, Cecilia; Colombo, SARA FRANCESCA
Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2-isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors.
2011 Dallanoce C; Magrone P; Matera C; Frigerio F; Grazioso G; De Amici M; Fucile S; Piccari V; Frydenvang K; Pucci L; Gotti C; Clementi F;De Micheli; C
Engineering of alpha-conotoxin MII-derived peptides with increased selectivity for native alpha 6 beta 2*nicotinic acetylcholine receptors
2011 Pucci, Luca; Grazioso, Giovanni; Dallanoce, Clelia; Rizzi, Luca; De Micheli, Carlo; Clementi, Francesco; Bertrand, Sonia; Bertrand, Daniel; Longhi, Renato; De Amici, Marco; Gotti, Cecilia
Expression of the alpha7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.
2011 Benfante, R; Antonini, ; R, A; De Pizzol, M; Gotti, C; Clementi, F; Locati, M; Fornasari, DIEGO MARIA MICHELE; D,
New spirocyclic Delta(2)-isoxazoline derivatives related to selective agonists of alpha7 neuronal nicotinic acetylcholine receptors.
2011 Dallanoce, C; Frigerio, F; Grazioso, G; Matera, C; Visconti, Gl; De Amici, M; Pucci, L; Pistillo, F; Fucile, S; Gotti, C; Clementi, F; De Micheli, C
A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes.
2010 Moretti M ; Mugnaini M; Tessari M ; Zoli M ; Gaimarri A; Manfredi I ; Pistillo F; Clementi F;Gotti C
Nicotinic Acetylcholine Receptors in the Mesolimbic Pathway: Primary Role of Ventral Tegmental Area alpha 6 beta 2*Receptors in Mediating Systemic Nicotine Effects on Dopamine Release, Locomotion, and Reinforcement
2010 Gotti C; Guiducci S; Tedesco V ; Corbioli S; Zanetti L; Moretti M; Zanardi A; Rimondini R; Mugnaini M; Clementi F; Chiamulera C;Zoli M
Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes.
2010 Dallanoce, C; Frigerio, F; Martelli, G; Grazioso, G; Matera, C; Pome, Dy; Pucci, L; Clementi, F; Gotti, C; Amici, Md
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based alpha7- and alpha9-nicotinic ligands on glioblastoma cells | 1-gen-2022 | Pucci S.; Bolchi C.; Bavo F.; Pallavicini M.; De Palma C.; Renzi M.; Fucile S.; Benfante R.; Di Lascio S.; Lattuada D.; Bessereau J.L.; D'Alessandro M.; Risson V.; Zoli M.; Clementi F.; Gotti C. | |
| Choline and nicotine increase glioblastoma cell proliferation by binding and activating alpha 7-and alpha 9-containing nicotinic receptors | 1-gen-2021 | Pucci, Susanna; Fasoli, Francesca; Moretti, Milena; Benfante, Roberta; Di Lascio, Simona; Viani, Paola; Daga, Antonio; Gordon Thomas, J; Mcintosh, Michael; Zoli, Michele; Clementi, Francesco; Gotti, Cecilia | |
| Persistent cognitive and affective alterations at late withdrawal stages after long-term intermittent exposure to tobacco smoke or electronic cigarette vapour: Behavioural changes and their neurochemical correlates | 1-gen-2020 | Ponzoni, Luisa; Braida, Daniela; Carboni, Lucia; Moretti, Milena; Viani, Paola; Clementi, Francesco; Zoli, Michele; Gotti, Cecilia; Sala, Mariaelvina | |
| Increased sensitivity to Delta(9)-THC-induced rewarding effects after seven-week exposure to electronic and tobacco cigarettes in mice | 1-gen-2019 | Ponzoni, L.; Moretti, M.; Braida, D.; Zoli, M.; Clementi, F.; Viani, P.; Sala, M.; Gotti, C. | |
| alfa9- and alfa7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line | 1-gen-2018 | Mucchietto, V; Fasoli, F; Pucci, S; Moretti, M; Benfante, R; Maroli, A; Di Lascio, S; Bolchi, C; Pallavicini, M; Dowell, C; Mcintosh, M; Clementi, F; Gotti, C | |
| Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an alpha 7-nAChR, alpha 9-nAChR Antagonist and of a Pro-Oxidant Mitocan | 1-gen-2018 | Bavo, Francesco; Pucci, Susanna; Fasoli, Francesca; Lammi, Carmen; Moretti, Milena; Mucchietto, Vanessa; Lattuada, Donatella; Viani, Paola; De Palma, Clara; Budriesi, Roberta; Corradini, Irene; Dowell, Cheryl; Mcintosh, J Michael; Clementi, Francesco; Bolchi, Cristiano; Gotti, Cecilia; Pallavicini, Marco | |
| In vivo chronic nicotine exposure differentially and reversibly affects upregulation and stoichiometry of ?4?2 nicotinic receptors in cortex and thalamus | 1-gen-2016 | Fasoli, F; Moretti, M; Zoli, M; Pistillo, F; Crespi, A; Clementi, F; Mc ClureBegley, T; Marks, Mj; Gotti, C | |
| Neuronal acetylcholine nicotinic receptors as new targets for lung cancer treatment | 1-gen-2016 | Mucchietto, V; Crespi, A; Fasoli, F; Clementi, F; Gotti, C | |
| Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice | 1-gen-2015 | Ponzoni, L; Moretti, M; Sala, M; Fasoli, F; Mucchietto, V; Lucini, V; Cannazza, G; Gallesi, G; Castellana, Cn; Clementi, F; Zoli, M; Gotti, C; Braida, D | |
| Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: Focus on nicotine effects | 1-gen-2015 | Pistillo, F.; Clementi, F.; Zoli, M.; Gotti, C. | |
| The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors | 1-gen-2014 | Ponzoni, L; Braida, D; Pucci, L; Andrea, D; Fasoli, F; Manfredi, I; Papke, Rl; Stokes, C; Cannazza, G; Clementi, F; Gotti, C; Sala, M | |
| CC4, a dimer of cytisine, is a selective partial agonist at alpha4beta2/alpha6beta2 nAChR with improved selectivity for tobacco smoking cessation | 1-gen-2013 | Sala, Mariaelvina; Braida, Daniela; Pucci, Luca; Manfredi, Irene; J Marks, Michael; R Wageman, Charles; R Grady, Sharon; Loi, Barbara; Fucile, Sergio; Fasoli, Francesca; Zoli, Michele; Tasso, Bruno; Sparatore, Fabio; Clementi, Francesco; Gotti, Cecilia | |
| Nicotine-modulated subunit stoichiometry affects stability and trafficking of alpha3beta4 nicotinic receptor | 1-gen-2013 | Mazzo, Francesca; Pistillo, Francesco; Grazioso, Giovanni; Clementi, Francesco; Borgese, Nica; Gotti, Cecilia; Colombo, SARA FRANCESCA | |
| Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2-isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors. | 1-gen-2011 | Dallanoce C; Magrone P; Matera C; Frigerio F; Grazioso G; De Amici M; Fucile S; Piccari V; Frydenvang K; Pucci L; Gotti C; Clementi F;De Micheli; C | |
| Engineering of alpha-conotoxin MII-derived peptides with increased selectivity for native alpha 6 beta 2*nicotinic acetylcholine receptors | 1-gen-2011 | Pucci, Luca; Grazioso, Giovanni; Dallanoce, Clelia; Rizzi, Luca; De Micheli, Carlo; Clementi, Francesco; Bertrand, Sonia; Bertrand, Daniel; Longhi, Renato; De Amici, Marco; Gotti, Cecilia | |
| Expression of the alpha7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS. | 1-gen-2011 | Benfante, R; Antonini, ; R, A; De Pizzol, M; Gotti, C; Clementi, F; Locati, M; Fornasari, DIEGO MARIA MICHELE; D, | |
| New spirocyclic Delta(2)-isoxazoline derivatives related to selective agonists of alpha7 neuronal nicotinic acetylcholine receptors. | 1-gen-2011 | Dallanoce, C; Frigerio, F; Grazioso, G; Matera, C; Visconti, Gl; De Amici, M; Pucci, L; Pistillo, F; Fucile, S; Gotti, C; Clementi, F; De Micheli, C | |
| A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes. | 1-gen-2010 | Moretti M ; Mugnaini M; Tessari M ; Zoli M ; Gaimarri A; Manfredi I ; Pistillo F; Clementi F;Gotti C | |
| Nicotinic Acetylcholine Receptors in the Mesolimbic Pathway: Primary Role of Ventral Tegmental Area alpha 6 beta 2*Receptors in Mediating Systemic Nicotine Effects on Dopamine Release, Locomotion, and Reinforcement | 1-gen-2010 | Gotti C; Guiducci S; Tedesco V ; Corbioli S; Zanetti L; Moretti M; Zanardi A; Rimondini R; Mugnaini M; Clementi F; Chiamulera C;Zoli M | |
| Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes. | 1-gen-2010 | Dallanoce, C; Frigerio, F; Martelli, G; Grazioso, G; Matera, C; Pome, Dy; Pucci, L; Clementi, F; Gotti, C; Amici, Md |