FIORANI, PAOLA
 Distribuzione geografica
Continente #
AS - Asia 1.086
NA - Nord America 537
EU - Europa 138
SA - Sud America 126
AF - Africa 25
OC - Oceania 2
Totale 1.914
Nazione #
US - Stati Uniti d'America 521
CN - Cina 404
SG - Singapore 350
BR - Brasile 103
HK - Hong Kong 91
KR - Corea 84
VN - Vietnam 75
FR - Francia 35
IN - India 20
FI - Finlandia 19
IT - Italia 19
NL - Olanda 15
JP - Giappone 14
GB - Regno Unito 13
DE - Germania 12
IL - Israele 12
CA - Canada 11
AR - Argentina 7
TN - Tunisia 6
BD - Bangladesh 5
EC - Ecuador 5
ID - Indonesia 5
RU - Federazione Russa 5
SA - Arabia Saudita 5
DZ - Algeria 4
KZ - Kazakistan 4
PL - Polonia 4
PY - Paraguay 4
SE - Svezia 4
TR - Turchia 4
ES - Italia 3
KE - Kenya 3
MX - Messico 3
ZA - Sudafrica 3
AL - Albania 2
AT - Austria 2
AU - Australia 2
BG - Bulgaria 2
CL - Cile 2
UZ - Uzbekistan 2
VE - Venezuela 2
AE - Emirati Arabi Uniti 1
AO - Angola 1
AZ - Azerbaigian 1
BB - Barbados 1
BW - Botswana 1
CO - Colombia 1
EG - Egitto 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GR - Grecia 1
GT - Guatemala 1
IQ - Iraq 1
JO - Giordania 1
KG - Kirghizistan 1
MU - Mauritius 1
MY - Malesia 1
NG - Nigeria 1
NP - Nepal 1
OM - Oman 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
SN - Senegal 1
TG - Togo 1
TW - Taiwan 1
UY - Uruguay 1
Totale 1.914
Città #
Hefei 242
Santa Clara 237
Singapore 208
Hong Kong 90
Seoul 84
Ashburn 44
Beijing 41
San Jose 37
Lauterbourg 33
Los Angeles 30
Council Bluffs 27
Ho Chi Minh City 27
Hanoi 17
Amsterdam 12
Bengaluru 11
Minamishinagawa 11
New York 11
Helsinki 10
Dallas 9
Lappeenranta 8
São Paulo 8
Denver 6
Montreal 6
Orem 6
Biên Hòa 5
Buffalo 5
Brasília 4
Frankfurt am Main 4
London 4
Chicago 3
Da Nang 3
Guayaquil 3
Jeddah 3
Miami 3
Nairobi 3
Phoenix 3
Rome 3
Stockholm 3
Tokyo 3
Warsaw 3
Alatri 2
Astana 2
Atlanta 2
Bauru 2
Belo Horizonte 2
Brooklyn 2
Chengdu 2
Chennai 2
Haiphong 2
Houston 2
Jakarta 2
Johannesburg 2
Katueté 2
Lấp Vò 2
Manchester 2
Milan 2
Mumbai 2
Ninh Bình 2
Poplar 2
Porto Alegre 2
Portsmouth 2
Resistencia 2
Reyhanlı 2
São Carlos 2
Tashkent 2
Thái Bình 2
Tirana 2
Tunis 2
Abaetetuba 1
Aberdeen 1
Adelaide 1
Algiers 1
Amman 1
Ankara 1
Apiaí 1
Aracaju 1
Arapiraca 1
Artur Nogueira 1
Athens 1
Bady Bassitt 1
Baghdad 1
Bahir Dar 1
Baku 1
Barnaul 1
Barueri 1
Beau Bassin-Rose Hill 1
Ben Arous 1
Blida 1
Bloomfield 1
Blumenau 1
Boa Esperança 1
Bogotá 1
Boston 1
Brescia 1
Bridgetown 1
Brusciano 1
Buritis 1
Bến Tre 1
Cairo 1
Cajazeiras 1
Totale 1.358
Nome #
Role of flexibility and long range communication on the function of human topoisomerase I 110
Cow Milk Extracellular Vesicle Effects on an In Vitro Model of Intestinal Inflammation 109
From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica 94
The open state of human topoisomerase I as probed by molecular dynamics simulation. 93
Natural compounds as therapeutic agents: The case of human topoisomerase ib 90
Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity 89
Dimethylmyricacene: An In Vitro and In Silico Study of a Semisynthetic Non-Camptothecin Derivative Compound, Targeting Human DNA Topoisomerase 1B 87
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations. 84
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance. 82
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation 77
Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I. 68
Topoisomerase IB: a relaxing enzyme for stressed DNA 59
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 52
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance 52
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study. 46
Mechanisms of DNA topoisomerase I-induced cell killing in the yeast: Saccharomyces cerevisiae 46
In vitro and in silico characterization of an antimalarial compound with antitumor activity targeting human DNA topoisomerase IB 46
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 44
Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate 44
Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing plasmodium parasites based on enzyme activity measurement 43
Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin. 41
In Silico Structural Modeling of the HuR-mRNA Complex: Insights into Structural and Functional Regulation 41
Replacement of the Human Topoisomerase Linker Domain with the Plasmodial Counterpart Renders the Enzyme Camptothecin Resistant 41
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation 39
Study of yeast DNA topoisomerase II and its truncation derivatives by transmission electron microscopy 38
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 37
The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons. 37
Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge Artemisina plumosa 37
Interaction between natural compounds and human topoisomerase i 37
CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I-mediated DNA damage 36
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 36
Protein concerted motions in the DNA-human topoisomerase I complex 35
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant. 35
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity 34
Camptothecin Resistance from a Single Mutation Changing Glycine 363 of Human DNA Topoisomerase I to Cysteine 34
Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification. 34
Mutations of human DNA topoisomerase I at poly (ADP-ribose) binding sites: Modulation of camptothecin activity by ADP-ribose polymers 33
Single Mutation in the Linker Domain Confers Protein Flexibility and Camptothecin Resistance to Human Topoisomerase I 29
Drug-induced stabilization of covalent DNA topoisomerase I-DNA intermediates - DNA cleavage assays 29
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant 28
Totale 2.126
Categoria #
all - tutte 6.046
article - articoli 5.785
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 96
Totale 11.927


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/2024197 0 0 0 0 0 0 0 0 0 0 0 197
2024/2025700 2 4 48 19 202 40 0 34 5 9 184 153
2025/20261.229 107 189 99 210 198 72 169 47 39 74 25 0
Totale 2.126