CNR Institutional Research Information System

FIORANI, PAOLA
 Distribuzione geografica
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Continente #
EU - Europa 3
AS - Asia 1
Totale 4
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Nazione #
IT - Italia 3
SG - Singapore 1
Totale 4
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Città #
Milan 2
Florence 1
Totale 3
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Nome #
Role of flexibility and long range communication on the function of human topoisomerase I 9
Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification. 9
The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons. 7
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 7
Natural compounds as therapeutic agents: The case of human topoisomerase ib 7
Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I. 6
The open state of human topoisomerase I as probed by molecular dynamics simulation. 6
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study. 6
Topoisomerase IB: a relaxing enzyme for stressed DNA 6
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 6
Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin. 6
CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I-mediated DNA damage 6
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations. 6
Single Mutation in the Linker Domain Confers Protein Flexibility and Camptothecin Resistance to Human Topoisomerase I 6
Study of yeast DNA topoisomerase II and its truncation derivatives by transmission electron microscopy 6
Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing plasmodium parasites based on enzyme activity measurement 6
Protein concerted motions in the DNA-human topoisomerase I complex 6
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity 6
Camptothecin Resistance from a Single Mutation Changing Glycine 363 of Human DNA Topoisomerase I to Cysteine 6
Mechanisms of DNA topoisomerase I-induced cell killing in the yeast: Saccharomyces cerevisiae 6
Interaction between natural compounds and human topoisomerase i 6
Replacement of the Human Topoisomerase Linker Domain with the Plasmodial Counterpart Renders the Enzyme Camptothecin Resistant 6
In vitro and in silico characterization of an antimalarial compound with antitumor activity targeting human DNA topoisomerase IB 6
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant. 6
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance. 5
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance 4
From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica 4
Drug-induced stabilization of covalent DNA topoisomerase I-DNA intermediates - DNA cleavage assays 4
Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity 3
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation 3
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 3
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation 3
Dimethylmyricacene: An In Vitro and In Silico Study of a Semisynthetic Non-Camptothecin Derivative Compound, Targeting Human DNA Topoisomerase 1B 3
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant 3
Cow Milk Extracellular Vesicle Effects on an In Vitro Model of Intestinal Inflammation 3
Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate 3
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 3
Mutations of human DNA topoisomerase I at poly (ADP-ribose) binding sites: Modulation of camptothecin activity by ADP-ribose polymers 3
Totale 200
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Categoria #
all - tutte 606
article - articoli 569
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 14
Totale 1.189
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/2024197 0 0 0 0 0 0 0 0 0 0 0 197
2024/20253 2 1 0 0 0 0 0 0 0 0 0 0
Totale 200