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LIGRESTI, ALESSIA

LIGRESTI, ALESSIA  

Istituto di Chimica Biomolecolare - ICB - Sede Pozzuoli  

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DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation 1-gen-2024 Alberga, Domenico; Lamanna, Giuseppe; Graziano, Giovanni; Delre, Pietro; Cristina Lomuscio, Maria; Corriero, Nicola; Ligresti, Alessia; Siliqi, Dritan; Saviano, Michele; Contino, Marialessandra; Stefanachi, Angela; Mangiatordi, GIUSEPPE FELICE
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization 1-gen-2024 Butini, Stefania; Grether, Uwe; Jung, Kwang-Mook; Ligresti, Alessia; Allarà, Marco; Postmus, Annemarieke G. J.; Maramai, Samuele; Brogi, Simone; Papa, Alessandro; Carullo, Gabriele; Sykes, David; Veprintsev, Dmitry; Federico, Stefano; Grillo, Alessandro; Di Guglielmo, Bruno; Ramunno, Anna; Floor Stevens, Anna; Heer, Dominik; Lamponi, Stefania; Gemma, Sandra; Benz, Jörg; DI MARZO, Vincenzo; van der Stelt, Mario; Piomelli, Daniele; Giuseppe Campiani, And
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R) 1-gen-2024 Intranuovo, F; Majellaro, M; Mastropasqua, F; Delre, P; Abatematteo, Fs; Mangiatordi, Gf; Stefanachi, A; Brea, J; Loza, Mi; Riganti, C; Ligresti, A; Kumar, P; Esposito, D; Cristino, L; Nicois, A; González, L; Perrone, Mg; Colabufo, Na; Sotelo, E; Abate, C; Contino, M.
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo 1-gen-2024 Mugnaini, Claudia; Brizzi, Antonella; Paolino, Marco; Scarselli, Enrico; Castelli, Riccardo; de Candia, Modesto; Gambacorta, Nicola; Nicolotti, Orazio; Kostrzewa, Magdalena; Kumar, Poulami; Mohamed, ALI MOKHTAR MAHMOUD; Borgonetti, Vittoria; Iannotta, Monica; Morace, Andrea; Galeotti, Nicoletta; Maione, Sabatino; Altomare, Cosimo D.; Ligresti, Alessia; Corelli, Federico
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone 1-gen-2024 Di Micco, Simone; Ciaglia, Tania; Salviati, Emanuela; Michela, Perrone; Kostrzewa, Magdalena; Musella, Simona; Moriello, Aniello Schiano; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Capolupo, Ilaria; Infantino, Rosmara; Bifulco, Giuseppe; Pepe, Giacomo; Sommella, Eduardo M; Kumar, Poulami; Basilicata, Manuela Giovanna; Allarà, Marco; Sanchez-Fernandez, Nuria; Aso, Ester; Gomez-Monterrey, Isabel; Campiglia, Pietro; Ostacolo, Carmine; Maione, Sabatino; Ligresti, Alessia; Bertamino, Alessia
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer 1-gen-2023 Mohamed, ALI MOKHTAR MAHMOUD; Kostrzewa, M.; Marolda, V.; Cerasuolo, M.; Maccarinelli, F.; Coltrini, D.; Rezzola, S.; Giacomini, A.; Mollica, M. P.; Motta, A.; Paris, D.; Zorzano, A.; Di Marzo, V.; Ronca, R.; Ligresti, A.
Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor 1-gen-2023 Bouma, Jara; D Broekhuis, Jeremy; van der Horst, Cas; Kumar, Poulami; Ligresti, Alessia; van der Stelt, Mario; H Heitman, Laura
Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer 1-gen-2023 Maccarinelli, Federica; Coltrini, Daniela; Mussi, Silvia; Bugatti, Mattia; Turati, Marta; Chiodelli, Paola; Giacomini, Arianna; De Cillis, Floriana; Cattane, Nadia; Cattaneo, Annamaria; Ligresti, Alessia; Asperti, Michela; Poli, Maura; Vermi, William; Presta, Marco; Ronca, Roberto
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists 1-gen-2023 Cho Analia Young, Hwa; Chung, Hery; Romeroparra, Javier; Kumar, Poulami; Allarà, Marco; Ligresti, Alessia; Gallardogarrido, Carlos; Pessoamahana, Hernán; Faúndez, Mario; PessoaMahana Carlos, David
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs 1-gen-2023 Graziano, Giovanni; Stefanachi, Angela; Contino, Marialessandra; Prietodíaz, Rubén; Ligresti, Alessia; Kumar, Poulami; Scilimati, Antonio; Sotelo, Eddy; Leonetti, Francesco
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) 1-gen-2023 Graziano, G; Delre, P; Carofiglio, F; Brea, J; Ligresti, A; Kostrzewa, M; Riganti, C; Gioegallo, C; Majellaro, M; Nicolotti, O; Colabufo, Na; Abate, C; Loza, Mi; Sotelo, E; Mangiatordi, Gf; Contino, M; Stefanachi, A; Leonetti, F
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor 1-gen-2023 Mugnaini, Claudia; Kostrzewa, Magdalena; Casini, Marta; Kumar, Poulami; Catallo, Valeria; Allarà, Marco; Guastaferro, Laura; Brizzi, Antonella; Paolino, Marco; Tafi, Andrea; Kapatais, Christelos; Giorgi, Gianluca; Vacondio, Federica; Mor, Marco; Corelli, Federico; Ligresti, Alessia
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 1-gen-2022 Intranuovo, Francesca; Brunetti, Leonardo; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Loza Maria, Isabel; Sotelo, Eddy; Saviano, Michele; Colabufo Nicola, Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra
FGFR blockade by pemigatinib treats naïve and castration resistant prostate cancer 1-gen-2022 Chiodelli, P; Coltrini, D; Turati, M; Cerasuolo, M; Maccarinelli, F; Rezzola, S; Grillo, E; Giacomini, A; Taranto, S; Mussi, S; Ligresti, A; Presta, M; Ronca, R
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation 1-gen-2022 Gianquinto, Eleonora; Sodano, Federica; Rolando, Barbara; Kostrzewa, Magdalena; Allara, Marco; Mohamed, ALI MOKHTAR MAHMOUD; Kumar, Poulami; Spyrakis, Francesca; Ligresti, Alessia; Chegaev, Konstantin
Biosynthesis of the novel endogenous 15-lipoxygenase metabolites N-13-hydroxy-octodecadienoyl-ethanolamine and 13-hydroxy-octodecadienoyl-glycerol by human neutrophils and Eosinophils 1-gen-2021 Archambault, As; Tinto, F; Dumais, E; Rakotoarivelo, V; Kostrzewa, M; Plante, Pl; Martin, C; Simard, M; Silvestri, C; Pouliot, R; Laviolette, M; Boulet, Lp; Vitale, Rm; Ligresti, A; Di Marzo, V; Flamand, N
Modulation of endocannabinoid tone in osteoblastic differentiation of mc3t3-e1 cells and in mouse bone tissue over time 1-gen-2021 Kostrzewa M.; Mahmoud A.M.; Verde R.; Di Carlo F.S.; Gianfrancesco F.; Piscitelli F.; Ligresti A.
New Coumarin derivatives as cholinergic and cannabinoid system modulators 1-gen-2021 Montanari, S; Allara, M; Scalvini, L; Kostrzewa, M; Belluti, F; Gobbi, S; Naldi, M; Rivara, S; Bartolini, M; Ligresti, A; Bisi, A; Rampa, A
Sesquiterpene lactones with the 12,8-guaianolide skeleton from algerian Centaurea omphalotricha 1-gen-2021 Kebbi, S.; Ciavatta, M. L.; Mahmoud, A. M.; Carbone, M.; Ligresti, A.; Seghiri, R.; Gavagnin Capoggiani, M.
Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva 1-gen-2021 Tinto, F; Archambault, As; Dumais, E; Rakotoarivelo, V; Kostrzewa, M; Martin, C; Plante, Pl; Desjardins, Y; Simard, M; Pouliot, R; De Petrocellis, L; Ligresti, A; Di Marzo, V; Flamand, N