SACCOCCIA, FULVIO
SACCOCCIA, FULVIO
Istituto di Biochimica e Biologia Cellulare - IBBC - Sede Secondaria Monterotondo
Characterizing a-GAL Mutants: Fom Misfolding to Rescue
2024 Monticelli, M.; Hay Mele, B.; Ogbodo John, O.; Saccoccia, F.; Papoff, G.; Cubellis, M. V.; Andreotti, G.
Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages
2024 Gimmelli, Roberto; Papoff, Giuliana; Saccoccia, Fulvio; Lalli, Cristiana; Gemma, Sandra; Campiani, Giuseppe; Ruberti, Giovina
100x100CNR. Incontri mattutini a IBBC con 100 studenti liceali del territorio
2023 DI LORENZO, Paolo; DI PIETRO, Chiara; Falchetti, MARIA LAURA; Marazziti, Daniela; Marinelli, Sara; Massimi, Marzia; Matteoni, Rafaele; Micheli, Laura; Mongiardi, MARIA PATRIZIA; Papoff, Giuliana; Parisi, Chiara; Pellegrini, Manuela; Saccoccia, Fulvio; Trono, Paola; Donati Tommaso Nastasi, Viola
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability
2022 A, Stefano Federico; A, Tuhina Khan; A, Anna Fontana; B, Simone Brogi; C, Rosaria Benedetti; C, Federica Sarno; A, Gabriele Carullo; D, Alex Pezzotta; A, Akella Prasanth Saraswati; C, Eugenia Passaro; A, Luca Pozzetti; A, Alessandro Papa; E, Nicola Relitti; A, Sandra Gemma; A, Stefania Butini; D, Anna Pistocchi; F, Anna Ramunno; G, Fabrizio Vincenzi; G, Katia Varani; H, Vanessa Tatangelo; H, Laura Patrussi; Baldari h, Cosima T.; H, Simona Saponara; H, Beatrice Gorelli; A, Stefania Lamponi; H, Massimo Valoti; Saccoccia, Fulvio; Giannaccari, Marialaura; Ruberti, Giovina; J, Daniel Herp; J, Manfred Jung; Altucci ck, Lucia; A, Giuseppe Campiani
Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites
2022 Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
2022 Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors
2021 Campiani, Giuseppe; Cavella, Caterina; Osko Jeremy, D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach Katy, M; Altucci, Lucia; Bradding, Peter; Christianson David, W; Gemma, Sandra; Prasse, Antje
(+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages
2020 Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma
Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy
2020 Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone
2020 Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation
2020 Relitti, Nicola; Prasanth Saraswati, A; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Herp, Daniel; Schmidtkunz, Karin; Saccoccia, Fulvio; Ruberti, Giovina; Ulivieri, Cristina; Vanni, Francesca; Sarno, Federica; Altucci, Lucia; Lamponi, Stefania; Jung, Manfred; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation
2020 Prasanth Saraswati, A; Relitti, Nicola; Brindisi, Margherita; D Osko, Jeremy; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; H McCabe, Niamh; C Turkington, Richard; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; P Kelly, Vincent; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; W Christianson, David; Campiani, Giuseppe
Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents
2019 Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G
Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability.
2019 Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G.
Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production
2018 Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G
Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.
2017 Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures
2014 Angelucci, Francesco; Morea, Veronica; Angelaccio, Sebastiana; Saccoccia, Fulvio; Contestabile, Roberto; Ilari, Andrea
Regulation of gene expression in the liver and adipose tissue by a new dual PPARalpha/gamma agonist
2009 Gilardi, F; Scotti, E; Mitro, N; Godio, C; Pochetti, G; Montanari, R; Saccoccia, F; Loiodice, F; Fracchiolla, G; Tortorella, P; Laghezza, A; Lavecchia, A; Novellino, E; Mazza, F; Crestani, M
Crystal Structure of PPARgamma Ligand Binding Domain complexed with a novel Partial Agonist: a new region of the hydrophobic pocket could be exploited for drug design
2008 Montanari R; Saccoccia F; Scotti E; Crestani M; Godio C; Gilardi F; Loiodice F; Fracchiolla G; Laghezza A; Tortorella P; Lavecchia A; Novellino E; Mazza F; Aschi M; Pochetti G.
Crystal structure of the PPAR-gamma ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design
2008 Montanari, R; Saccoccia, F; Scotti, E; Crestani, M; Godio, C; Gilardi, F; Loiodice, F; Fracchiolla, G; Laghezza, A; Tortorella, P; Lavecchia, A; Novellino, E; Mazza, F; Pochetti, G
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Characterizing a-GAL Mutants: Fom Misfolding to Rescue | 1-gen-2024 | Monticelli, M.; Hay Mele, B.; Ogbodo John, O.; Saccoccia, F.; Papoff, G.; Cubellis, M. V.; Andreotti, G. | |
| Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages | 1-gen-2024 | Gimmelli, Roberto; Papoff, Giuliana; Saccoccia, Fulvio; Lalli, Cristiana; Gemma, Sandra; Campiani, Giuseppe; Ruberti, Giovina | |
| 100x100CNR. Incontri mattutini a IBBC con 100 studenti liceali del territorio | 1-gen-2023 | DI LORENZO, Paolo; DI PIETRO, Chiara; Falchetti, MARIA LAURA; Marazziti, Daniela; Marinelli, Sara; Massimi, Marzia; Matteoni, Rafaele; Micheli, Laura; Mongiardi, MARIA PATRIZIA; Papoff, Giuliana; Parisi, Chiara; Pellegrini, Manuela; Saccoccia, Fulvio; Trono, Paola; Donati Tommaso Nastasi, Viola | |
| Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability | 1-gen-2022 | A, Stefano Federico; A, Tuhina Khan; A, Anna Fontana; B, Simone Brogi; C, Rosaria Benedetti; C, Federica Sarno; A, Gabriele Carullo; D, Alex Pezzotta; A, Akella Prasanth Saraswati; C, Eugenia Passaro; A, Luca Pozzetti; A, Alessandro Papa; E, Nicola Relitti; A, Sandra Gemma; A, Stefania Butini; D, Anna Pistocchi; F, Anna Ramunno; G, Fabrizio Vincenzi; G, Katia Varani; H, Vanessa Tatangelo; H, Laura Patrussi; Baldari h, Cosima T.; H, Simona Saponara; H, Beatrice Gorelli; A, Stefania Lamponi; H, Massimo Valoti; Saccoccia, Fulvio; Giannaccari, Marialaura; Ruberti, Giovina; J, Daniel Herp; J, Manfred Jung; Altucci ck, Lucia; A, Giuseppe Campiani | |
| Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites | 1-gen-2022 | Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina | |
| Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors | 1-gen-2022 | Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G | |
| Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors | 1-gen-2021 | Campiani, Giuseppe; Cavella, Caterina; Osko Jeremy, D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach Katy, M; Altucci, Lucia; Bradding, Peter; Christianson David, W; Gemma, Sandra; Prasse, Antje | |
| (+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages | 1-gen-2020 | Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma | |
| Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy | 1-gen-2020 | Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G | |
| Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone | 1-gen-2020 | Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M. | |
| Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation | 1-gen-2020 | Relitti, Nicola; Prasanth Saraswati, A; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Herp, Daniel; Schmidtkunz, Karin; Saccoccia, Fulvio; Ruberti, Giovina; Ulivieri, Cristina; Vanni, Francesca; Sarno, Federica; Altucci, Lucia; Lamponi, Stefania; Jung, Manfred; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe | |
| Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation | 1-gen-2020 | Prasanth Saraswati, A; Relitti, Nicola; Brindisi, Margherita; D Osko, Jeremy; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; H McCabe, Niamh; C Turkington, Richard; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; P Kelly, Vincent; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; W Christianson, David; Campiani, Giuseppe | |
| Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents | 1-gen-2019 | Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G | |
| Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability. | 1-gen-2019 | Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G. | |
| Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production | 1-gen-2018 | Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G | |
| Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production. | 1-gen-2017 | Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G | |
| The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures | 1-gen-2014 | Angelucci, Francesco; Morea, Veronica; Angelaccio, Sebastiana; Saccoccia, Fulvio; Contestabile, Roberto; Ilari, Andrea | |
| Regulation of gene expression in the liver and adipose tissue by a new dual PPARalpha/gamma agonist | 1-gen-2009 | Gilardi, F; Scotti, E; Mitro, N; Godio, C; Pochetti, G; Montanari, R; Saccoccia, F; Loiodice, F; Fracchiolla, G; Tortorella, P; Laghezza, A; Lavecchia, A; Novellino, E; Mazza, F; Crestani, M | |
| Crystal Structure of PPARgamma Ligand Binding Domain complexed with a novel Partial Agonist: a new region of the hydrophobic pocket could be exploited for drug design | 1-gen-2008 | Montanari R; Saccoccia F; Scotti E; Crestani M; Godio C; Gilardi F; Loiodice F; Fracchiolla G; Laghezza A; Tortorella P; Lavecchia A; Novellino E; Mazza F; Aschi M; Pochetti G. | |
| Crystal structure of the PPAR-gamma ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design | 1-gen-2008 | Montanari, R; Saccoccia, F; Scotti, E; Crestani, M; Godio, C; Gilardi, F; Loiodice, F; Fracchiolla, G; Laghezza, A; Tortorella, P; Lavecchia, A; Novellino, E; Mazza, F; Pochetti, G |