SACCOCCIA, FULVIO
SACCOCCIA, FULVIO
Istituto di Biochimica e Biologia Cellulare - IBBC
Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites
2022 Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
2022 Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors
2021 Campiani, Giuseppe; Cavella, Caterina; Osko Jeremy, D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach Katy, M; Altucci, Lucia; Bradding, Peter; Christianson David, W; Gemma, Sandra; Prasse, Antje
(+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages
2020 Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma
Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy
2020 Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone
2020 Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation
2020 Relitti, Nicola; Prasanth Saraswati, A; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Herp, Daniel; Schmidtkunz, Karin; Saccoccia, Fulvio; Ruberti, Giovina; Ulivieri, Cristina; Vanni, Francesca; Sarno, Federica; Altucci, Lucia; Lamponi, Stefania; Jung, Manfred; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation
2020 Prasanth Saraswati, A; Relitti, Nicola; Brindisi, Margherita; D Osko, Jeremy; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; H McCabe, Niamh; C Turkington, Richard; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; P Kelly, Vincent; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; W Christianson, David; Campiani, Giuseppe
Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents
2019 Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G
Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability.
2019 Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G.
Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production
2018 Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G
Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.
2017 Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Comparative metabolic profiling by H-1-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites | 1-gen-2022 | Fustaino, Valentina; Gimmelli, Roberto; Guidi, Alessandra; Lentini, Sara; Saccoccia, Fulvio; Petrella, Greta; Cicero Daniel, Oscar; Ruberti, Giovina | |
| Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors | 1-gen-2022 | Saccoccia, F; Pozzetti, L; Gimmelli, R; Butini, S; Guidi, A; Papoff, G; Giannaccari, M; Brogi, S; Scognamiglio, V; Gemma, S; Ruberti, G; Campiani, G | |
| Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors | 1-gen-2021 | Campiani, Giuseppe; Cavella, Caterina; Osko Jeremy, D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach Katy, M; Altucci, Lucia; Bradding, Peter; Christianson David, W; Gemma, Sandra; Prasse, Antje | |
| (+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages | 1-gen-2020 | Alessandra Guidi ; A Prasanth Saraswati ; Nicola Relitti ; Roberto Gimmelli ; Fulvio Saccoccia ; Carmina Sirignano ; Orazio TaglialatelaScafati ; Giuseppe Campiani ; Giovina Ruberti ; Sandra Gemma | |
| Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy | 1-gen-2020 | Guidi, A; Petrella, G; Fustaino, V; Saccoccia, F; Lentini, S; Gimmelli, R; Di Pietro, G; Bresciani, A; Cicero, Do; Ruberti, G | |
| Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone | 1-gen-2020 | Imperatore C.; Gimmelli R.; Persico M.; Casertano M.; Guidi A.; Saccoccia F.; Ruberti G.; Luciano P.; Aiello A.; Parapini S.; Avunduk S.; Basilico N.; Fattorusso C.; Menna M. | |
| Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation | 1-gen-2020 | Relitti, Nicola; Prasanth Saraswati, A; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Herp, Daniel; Schmidtkunz, Karin; Saccoccia, Fulvio; Ruberti, Giovina; Ulivieri, Cristina; Vanni, Francesca; Sarno, Federica; Altucci, Lucia; Lamponi, Stefania; Jung, Manfred; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe | |
| Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation | 1-gen-2020 | Prasanth Saraswati, A; Relitti, Nicola; Brindisi, Margherita; D Osko, Jeremy; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; H McCabe, Niamh; C Turkington, Richard; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; P Kelly, Vincent; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; W Christianson, David; Campiani, Giuseppe | |
| Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents | 1-gen-2019 | Saccoccia, F; Brindisi, M; Gimmelli, R; Relitti, N; Guidi, A; Saraswati, Ap; Cavella, C; Brogi, S; Chemi, G; Butini, S; Papoff, G; Senger, J; Herp, D; Jung, M; Campiani, G; Gemma, S; Ruberti, G | |
| Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability. | 1-gen-2019 | Gimmelli R; Persico M; Imperatore C; Saccoccia F; Guidi A; Casertano M; Luciano P; Pietrantoni A; Bertuccini L; Paladino A; Papoff G; Menna M; Fattorusso C; Ruberti G. | |
| Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production | 1-gen-2018 | Guidi, A; Saccoccia, F; Gennari, N; Gimmelli, R; Nizi, E; Lalli, C; Paonessa, G; Papoff, G; Bresciani, A; Ruberti, G | |
| Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production. | 1-gen-2017 | Guidi, A; Lalli, C; Gimmelli, R; Nizi, E; Andreini, M; Gennari, N; Saccoccia, F; Harper, S; Bresciani, A; Ruberti, G |