EXERTIER, CECILE
EXERTIER, CECILE
Istituto di Biologia e Patologia Molecolari - IBPM
Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis
2025 Exertier, Cecile; Antonelli, Lorenzo; Brufani, Vittorio; Colotti, Gianni; Ilari, Andrea; Fiorillo, Annarita
Gaseous ligand binding to Porphyromonas gingivalis HmuY hemophore-like protein in complex with heme
2025 Exertier, Cecile; Montemiglio, Linda Celeste; Tognaccini, Lorenzo; Zamparelli, Carlotta; Vallone, Beatrice; Olczak, Teresa; Śmiga, Michał; Smulevich, Giulietta; Malatesta, Francesco
Molecular Insights into IAHSP: Influence of the R1611W Mutation on the VPS9 Domain of Alsin
2025 Miceli, Marcello; Exertier, Cecile; Gugole, Elena; Vallone, Beatrice; Agostino Deriu, Marco
Specialty grand challenges in theoretical modeling, structure prediction and design
2025 Exertier, C.; Ilari, A.
Binding of steroid substrates reveals the key to the productive transition of the cytochrome P450 OleP
2024 Costanzo, Antonella; Fata, Francesca; Freda, Ida; De Sciscio, Maria Laura; Gugole, Elena; Bulfaro, Giovanni; Di Renzo, Matteo; Barbizzi, Luca; Exertier, Cécile; Parisi, Giacomo; D'Abramo, Marco; Vallone, Beatrice; Savino, Carmelinda; Montemiglio, Linda Celeste
ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds
2024 Zineddu, S.; Geri, A.; Ilari, A.; Colotti, G.; Exertier, C.; Fiorillo, A.; Antonelli, L.; Messori, L.
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis
2024 Exertier, Cecile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance
2024 Exertier, C.; Antonelli, L.; Fiorillo, A.; Bernardini, R.; Colotti, B.; Ilari, A.; Colotti, G.
7ZLA: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation
2023 Freda I.; Montemiglio L.C.; Tramonti A.; Contestabile R.; Vallone B.; Savino C.; Exertier C.; Bolognesi M.; Chaves Sanjuan A.
7ZN5: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry
2023 Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A
7ZPA: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C1 symmetry
2023 Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A
7ZTH: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation
2023 Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A
Effect of salts on the conformational dynamics of the cytochrome P450 OleP
2023 De Sciscio, M L; Nardi, A N; Parisi, G; Bulfaro, G; Costanzo, A; Gugole, E; Exertier, C; Freda, I; Savino, C; Vallone, B; Montemiglio, LINDA CELESTE; D'Abramo, M
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site
2023 Madia, Vn; Ialongo, D; Patacchini, E; Exertier, C; Antonelli, L; Colotti, G; Messore, A; Tudino, V; Saccoliti, F; Scipione, L; Ilari, A; Costi, R; Di Santo, R
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR
2023 Freda, I; Exertier, C; Barile, A; Chavessanjuan, A; Vega, Mv; Isupov, Mn; Harmer, Nj; Gugole, E; Swuec, P; Bolognesi, M; Scipioni, A; Savino, C; Di Salvo, Ml; Contestabile, R; Vallone, B; Tramonti, A; Montemiglio, Lc
7Q6R: OleP mutant E89Y in complex with 6DEB
2022 Savino, C; Montemiglio, LINDA CELESTE; L, C; Vallone, B; Exertier, C; Freda, I; Gugole, ; E,
7Q6X: OleP mutant S240Y in complex with 6DEB
2022 Savino, C; Montemiglio, LINDA CELESTE; L, C; Vallone, B; Exertier, C; Freda, I; Gugole, ; E,
7Q89 OleP mutant G92W in complex with 6DEB
2022 Savino C; Montemiglio; L C; Vallone B; Exertier C; Freda I; Gugole; E
ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules
2022 Miceli, Marcello; Exertier, Cecile; Cavaglià, Marco; Gugole, Elena; Boccardo, Marta; Casaluci, Rossana Rita; Ceccarelli, Noemi; De Maio, Alessandra; Vallone, Beatrice; Deriu, Marco A.
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design
2022 Fiorillo, A; Colotti, G; Exertier, C; Liuzzi, A; Seghetti, F; Salerno, A; Caciolla, J; Ilari, A
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis | 1-gen-2025 | Exertier, Cecile; Antonelli, Lorenzo; Brufani, Vittorio; Colotti, Gianni; Ilari, Andrea; Fiorillo, Annarita | |
| Gaseous ligand binding to Porphyromonas gingivalis HmuY hemophore-like protein in complex with heme | 1-gen-2025 | Exertier, Cecile; Montemiglio, Linda Celeste; Tognaccini, Lorenzo; Zamparelli, Carlotta; Vallone, Beatrice; Olczak, Teresa; Śmiga, Michał; Smulevich, Giulietta; Malatesta, Francesco | |
| Molecular Insights into IAHSP: Influence of the R1611W Mutation on the VPS9 Domain of Alsin | 1-gen-2025 | Miceli, Marcello; Exertier, Cecile; Gugole, Elena; Vallone, Beatrice; Agostino Deriu, Marco | |
| Specialty grand challenges in theoretical modeling, structure prediction and design | 1-gen-2025 | Exertier, C.; Ilari, A. | |
| Binding of steroid substrates reveals the key to the productive transition of the cytochrome P450 OleP | 1-gen-2024 | Costanzo, Antonella; Fata, Francesca; Freda, Ida; De Sciscio, Maria Laura; Gugole, Elena; Bulfaro, Giovanni; Di Renzo, Matteo; Barbizzi, Luca; Exertier, Cécile; Parisi, Giacomo; D'Abramo, Marco; Vallone, Beatrice; Savino, Carmelinda; Montemiglio, Linda Celeste | |
| ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds | 1-gen-2024 | Zineddu, S.; Geri, A.; Ilari, A.; Colotti, G.; Exertier, C.; Fiorillo, A.; Antonelli, L.; Messori, L. | |
| Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis | 1-gen-2024 | Exertier, Cecile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura | |
| Sorcin in Cancer Development and Chemotherapeutic Drug Resistance | 1-gen-2024 | Exertier, C.; Antonelli, L.; Fiorillo, A.; Bernardini, R.; Colotti, B.; Ilari, A.; Colotti, G. | |
| 7ZLA: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation | 1-gen-2023 | Freda I.; Montemiglio L.C.; Tramonti A.; Contestabile R.; Vallone B.; Savino C.; Exertier C.; Bolognesi M.; Chaves Sanjuan A. | |
| 7ZN5: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry | 1-gen-2023 | Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A | |
| 7ZPA: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C1 symmetry | 1-gen-2023 | Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A | |
| 7ZTH: Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation | 1-gen-2023 | Freda, I; Montemiglio, Lc; Tramonti, A; Contestabile, R; Vallone, B; Savino, C; Exertier, C; Bolognesi, M; Chaves Sanjuan, A | |
| Effect of salts on the conformational dynamics of the cytochrome P450 OleP | 1-gen-2023 | De Sciscio, M L; Nardi, A N; Parisi, G; Bulfaro, G; Costanzo, A; Gugole, E; Exertier, C; Freda, I; Savino, C; Vallone, B; Montemiglio, LINDA CELESTE; D'Abramo, M | |
| Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site | 1-gen-2023 | Madia, Vn; Ialongo, D; Patacchini, E; Exertier, C; Antonelli, L; Colotti, G; Messore, A; Tudino, V; Saccoliti, F; Scipione, L; Ilari, A; Costi, R; Di Santo, R | |
| Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR | 1-gen-2023 | Freda, I; Exertier, C; Barile, A; Chavessanjuan, A; Vega, Mv; Isupov, Mn; Harmer, Nj; Gugole, E; Swuec, P; Bolognesi, M; Scipioni, A; Savino, C; Di Salvo, Ml; Contestabile, R; Vallone, B; Tramonti, A; Montemiglio, Lc | |
| 7Q6R: OleP mutant E89Y in complex with 6DEB | 1-gen-2022 | Savino, C; Montemiglio, LINDA CELESTE; L, C; Vallone, B; Exertier, C; Freda, I; Gugole, ; E, | |
| 7Q6X: OleP mutant S240Y in complex with 6DEB | 1-gen-2022 | Savino, C; Montemiglio, LINDA CELESTE; L, C; Vallone, B; Exertier, C; Freda, I; Gugole, ; E, | |
| 7Q89 OleP mutant G92W in complex with 6DEB | 1-gen-2022 | Savino C; Montemiglio; L C; Vallone B; Exertier C; Freda I; Gugole; E | |
| ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules | 1-gen-2022 | Miceli, Marcello; Exertier, Cecile; Cavaglià, Marco; Gugole, Elena; Boccardo, Marta; Casaluci, Rossana Rita; Ceccarelli, Noemi; De Maio, Alessandra; Vallone, Beatrice; Deriu, Marco A. | |
| Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design | 1-gen-2022 | Fiorillo, A; Colotti, G; Exertier, C; Liuzzi, A; Seghetti, F; Salerno, A; Caciolla, J; Ilari, A |