Knowledge of the three-dimensional (3D) structure of biological macromolecules (proteins, nucleic acids, and complex macromolecular assemblies) is essential to understand their function and therefore the metabolic process to which they belong. Moreover, the structural information of protein targets involved in physio-pathological processes can be used for structure-based drug design.

Specialty grand challenges in theoretical modeling, structure prediction and design

Exertier C.;Ilari A.
2025

Abstract

Knowledge of the three-dimensional (3D) structure of biological macromolecules (proteins, nucleic acids, and complex macromolecular assemblies) is essential to understand their function and therefore the metabolic process to which they belong. Moreover, the structural information of protein targets involved in physio-pathological processes can be used for structure-based drug design.
2025
Istituto di Biologia e Patologia Molecolari - IBPM
structure prediction, MD simulation, NMR, X-ray crystallography, cryo-electron microscopy structure-based-drug-design
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/559870
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