CNR Institutional Research Information System

ILARI, ANDREA
 Distribuzione geografica
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Continente #
AS - Asia 2.366
NA - Nord America 990
EU - Europa 510
SA - Sud America 481
AF - Africa 47
OC - Oceania 3
Totale 4.397
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Nazione #
SG - Singapore 978
US - Stati Uniti d'America 950
CN - Cina 608
BR - Brasile 392
HK - Hong Kong 249
VN - Vietnam 229
IT - Italia 153
FR - Francia 121
KR - Corea 93
NL - Olanda 61
IN - India 48
JP - Giappone 39
FI - Finlandia 32
DE - Germania 30
AR - Argentina 26
GB - Regno Unito 26
EC - Ecuador 21
BD - Bangladesh 20
CA - Canada 18
ID - Indonesia 14
IL - Israele 14
PY - Paraguay 12
EG - Egitto 11
TR - Turchia 11
ZA - Sudafrica 11
VE - Venezuela 10
ES - Italia 9
MX - Messico 9
SA - Arabia Saudita 9
AT - Austria 8
IQ - Iraq 8
PE - Perù 8
PK - Pakistan 8
SE - Svezia 8
RU - Federazione Russa 7
LT - Lituania 6
UZ - Uzbekistan 6
AZ - Azerbaigian 5
JO - Giordania 5
KE - Kenya 5
CH - Svizzera 4
HU - Ungheria 4
IE - Irlanda 4
LU - Lussemburgo 4
MA - Marocco 4
PL - Polonia 4
TN - Tunisia 4
UY - Uruguay 4
AL - Albania 3
CL - Cile 3
CO - Colombia 3
ET - Etiopia 3
KZ - Kazakistan 3
LV - Lettonia 3
PH - Filippine 3
PT - Portogallo 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
BO - Bolivia 2
BY - Bielorussia 2
CR - Costa Rica 2
EE - Estonia 2
HR - Croazia 2
JM - Giamaica 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
TH - Thailandia 2
UA - Ucraina 2
AM - Armenia 1
AO - Angola 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BE - Belgio 1
BM - Bermuda 1
BS - Bahamas 1
CM - Camerun 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
DZ - Algeria 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
HT - Haiti 1
IS - Islanda 1
KG - Kirghizistan 1
LB - Libano 1
LK - Sri Lanka 1
LY - Libia 1
MD - Moldavia 1
MT - Malta 1
MV - Maldive 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
RO - Romania 1
RW - Ruanda 1
Totale 4.391
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Città #
Singapore 547
Santa Clara 365
Hefei 248
Hong Kong 246
San Jose 121
Lauterbourg 99
Seoul 92
Beijing 87
Ho Chi Minh City 86
Ashburn 76
Rome 63
Hanoi 51
Los Angeles 45
São Paulo 35
Tokyo 26
Dallas 22
New York 22
Bengaluru 19
Lappeenranta 17
Frankfurt am Main 15
Da Nang 14
Rio de Janeiro 14
Helsinki 13
Minamishinagawa 13
Amsterdam 11
Brooklyn 11
Haiphong 11
Johannesburg 9
Porto Alegre 9
Campinas 8
Montreal 8
Buffalo 7
Quito 7
Stockholm 7
Council Bluffs 6
Damanhur 6
Düsseldorf 6
Guarulhos 6
Lima 6
Orem 6
Tashkent 6
Thái Bình 6
Amman 5
Asunción 5
Baghdad 5
Belo Horizonte 5
Brasília 5
Chennai 5
Curitiba 5
Guayaquil 5
Jilin 5
London 5
Milan 5
Nairobi 5
Paris 5
Portsmouth 5
Riyadh 5
Shanghai 5
Baku 4
Bắc Ninh 4
Ciudad del Este 4
Denver 4
Dublin 4
Duque de Caxias 4
Fortaleza 4
Manaus 4
Mexico City 4
Millepini 4
Nuremberg 4
Oklahoma City 4
Pescara 4
Recife 4
San Francisco 4
Thái Nguyên 4
Turin 4
Vienna 4
Warsaw 4
Zurich 4
Addis Ababa 3
Biên Hòa 3
Caxias do Sul 3
Changsha 3
Cleveland 3
Cotia 3
Dhaka 3
Hyderabad 3
Islamabad 3
Istanbul 3
Jeddah 3
Kingston 3
Madrid 3
Manchester 3
Newark 3
Ninh Bình 3
Nova Iguaçu 3
Osasco 3
Phoenix 3
Piracicaba 3
Poplar 3
Portogruaro 3
Totale 2.698
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Nome #
Identification of the pyridoxal 5?-phosphate allosteric site in human pyridox(am)ine 5?-phosphate oxidase 114
The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target 109
Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. 84
Study of manganese binding to the ferroxidase centre of human H-type ferritin 82
Covid-19: biologia molecolare e infezioni virali 77
Iron incorporation into Escherichia coli Dps gives rise to a ferritin-like microcrystalline core 73
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 71
Two different crystal forms of sorcin, a penta-EF-hand Ca2+-binding protein 69
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming 68
AI is a viable alternative to high throughput screening: a 318-target study 66
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 64
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 63
Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors 61
The Crystal Structure of Giardia duodenalis 14-3-3 in the Apo Form: When Protein Post-Translational Modifications Make the Difference 60
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 59
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design 59
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach 59
Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa 58
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 57
A Practical Approach to Protein Crystallography. 55
Escherichia coli flavohemoglobin is an efficient alkylhydroperoxide reductase. 55
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin 55
Reassessment of Protein Stability, DNA Binding, and Protection of Mycobacterium smegmatis Dps. 54
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 54
Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands 54
The Salmonella enterica ZinT structure, zinc affinity and interaction with the high-affinity Uptake protein ZnuA provide insight into the management of periplasmic zinc 52
ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds 52
Silver ion incorporation and nanoparticle formation inside the cavity of Pyrococcus furiosus ferritin: structural and size-distribution analyses. 51
Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing. A study with site-specific mutants 51
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 51
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 49
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 47
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase 47
Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum. 44
Addition to C-N Bonds 43
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 42
Structural basis of enzymatic S-norcoclaurine biosynthesis. 42
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. 42
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target 42
. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs. 41
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 41
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity. 41
ITMI20120980 (A1) - PYRROLYL-HYDROXAMATES FOR USE IN THE PREVENTION AND/OR TREATMENT OF BACTERIAL INFECTIONS 41
ZnuA, the soluble component of the bacterial Zn(II) ABC transporter, a possible target for novel antibiotics 40
Structural studies on flavohemoglobins. 40
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme 39
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 39
Protein structure determination by x-ray crystallography 39
The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site 38
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 38
Thermosynechococcus elongatus DpsA binds Zn(II) at a unique three histidine-containing ferroxidase center and utilizes O2 as iron oxidant with very high efficiency, unlike the typical Dps proteins 38
Sorcin 38
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 36
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 36
The X-ray structure of the zinc transporter ZnuA from Salmonella enterica discloses a unique triad of zinc-coordinating histidines 35
Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system. 35
A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca 35
Role of a Conserved Active Site Cation-pi Interaction in Escherichia coli Serine Hydroxymethyltransferase. 34
Metals and metal derivatives in medicine 34
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures 34
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress 34
The crystal structure of the sorcin calcium binding domain provides a model of Ca2+-dependent processes in the full-length protein 34
Target highlights in CASP14: Analysis of models by structure providers 33
Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis 32
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 31
The truncated oxygen-avid hemoglobin from Bacillus subtilis: X-ray structure and ligand binding properties. 31
Plasticity of secondary structure in the N-terminal region of beta-dystroglycan 31
Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells 31
The Dps protein of Agrobacterium tumefaciens does not bind to DNA but protects it toward oxidative cleavage: x-ray crystal structure, iron binding, and hydroxyl-radical scavenging properties. 30
Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells - A ferritin-like DNA-binding protein of Escherichia coli 30
The X-ray structure of trypanothione reductase in complex with NADPH and Sb(III) discloses the molecular basis of antimony treatment in leishmaniasis 30
Crystal structure and ligand binding properties of the truncated hemoglobin from Geobacillus stearothermophilus. 29
What is the future of the CNR? 29
Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis 29
Plasticity of secondary structure in the N-terminal region of beta-dystroglycan. 29
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming 28
Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation 28
Polyamine metabolism in Leishmania: from arginine to trypanothione 28
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions 28
Disclosing the Molecular Mechanism of Iron Incorporation in Listeria innocua Dps by EPR Spectroscopy 28
Unusual heme iron-lipid acyl chain coordination in Escherichia coli flavohemoglobin. 27
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. 27
Biomimetic Materials Synthesis from Ferritin-Related, Cage-Shaped Proteins 26
New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism 26
Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter 26
Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage 26
The unusual intersubunit ferroxidase center of Listeria innocua Dps is required for hydrogen peroxide detoxification but not for iron uptake. A study with site-specific mutants. 26
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 26
The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unexpected geometry of the distal heme pocket 25
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 25
The antioxidant Dps protein from the thermophilic cyanobacterium Thermosynechococcus elongatus: an intrinsically stable cage-like structure endowed with enhanced stability 25
Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening 24
Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins 23
Structural basis of Sorcin-mediated calcium-dependent signal transduction. 23
Targeting polyamine metabolism for finding new drugs against leishmaniasis: A review 23
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition 23
Iron and proteins for iron storage and detoxification. 22
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? 22
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 21
Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis 21
Totale 4.217
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Categoria #
all - tutte 15.022
article - articoli 14.006
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 896
Totale 29.924
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/20246 0 0 0 0 0 0 0 0 1 0 0 5
2024/20251.740 5 7 132 64 340 127 46 110 75 96 394 344
2025/20262.759 145 329 274 477 480 103 411 178 141 148 70 3
Totale 4.505