CNR Institutional Research Information System

ILARI, ANDREA
 Distribuzione geografica
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Continente #
AS - Asia 1.927
NA - Nord America 754
SA - Sud America 465
EU - Europa 319
AF - Africa 42
OC - Oceania 2
Totale 3.509
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Nazione #
SG - Singapore 843
US - Stati Uniti d'America 724
CN - Cina 423
BR - Brasile 381
HK - Hong Kong 223
VN - Vietnam 179
IT - Italia 107
KR - Corea 92
NL - Olanda 53
IN - India 44
DE - Germania 26
AR - Argentina 25
FI - Finlandia 24
FR - Francia 22
GB - Regno Unito 22
JP - Giappone 22
EC - Ecuador 21
BD - Bangladesh 15
IL - Israele 14
ID - Indonesia 12
PY - Paraguay 12
EG - Egitto 11
CA - Canada 10
ZA - Sudafrica 10
MX - Messico 9
PE - Perù 8
SA - Arabia Saudita 8
SE - Svezia 8
TR - Turchia 8
AT - Austria 7
ES - Italia 7
IQ - Iraq 7
RU - Federazione Russa 7
VE - Venezuela 7
PK - Pakistan 6
UZ - Uzbekistan 6
AZ - Azerbaigian 5
JO - Giordania 4
KE - Kenya 4
LT - Lituania 4
LU - Lussemburgo 4
MA - Marocco 4
UY - Uruguay 4
AL - Albania 3
CL - Cile 3
CO - Colombia 3
IE - Irlanda 3
KZ - Kazakistan 3
PL - Polonia 3
PT - Portogallo 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
CH - Svizzera 2
CR - Costa Rica 2
EE - Estonia 2
ET - Etiopia 2
LV - Lettonia 2
PH - Filippine 2
TH - Thailandia 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BM - Bermuda 1
BO - Bolivia 1
BS - Bahamas 1
BY - Bielorussia 1
CM - Camerun 1
CZ - Repubblica Ceca 1
DZ - Algeria 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HT - Haiti 1
IS - Islanda 1
JM - Giamaica 1
KG - Kirghizistan 1
LK - Sri Lanka 1
MD - Moldavia 1
MV - Maldive 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
RO - Romania 1
RW - Ruanda 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SV - El Salvador 1
TG - Togo 1
TT - Trinidad e Tobago 1
UA - Ucraina 1
UG - Uganda 1
Totale 3.509
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Città #
Singapore 490
Santa Clara 363
Hefei 248
Hong Kong 221
Seoul 92
Beijing 76
Ho Chi Minh City 67
Rome 59
Ashburn 48
San Jose 48
Hanoi 41
São Paulo 34
Los Angeles 28
Dallas 20
Bengaluru 19
Rio de Janeiro 14
Helsinki 13
Minamishinagawa 13
Frankfurt am Main 12
Haiphong 10
New York 10
Brooklyn 9
Da Nang 9
Lappeenranta 9
Tokyo 9
Campinas 8
Johannesburg 8
Porto Alegre 8
Quito 7
Stockholm 7
Amsterdam 6
Buffalo 6
Damanhur 6
Düsseldorf 6
Lima 6
Tashkent 6
Asunción 5
Baghdad 5
Belo Horizonte 5
Brasília 5
Curitiba 5
Guarulhos 5
Guayaquil 5
Portsmouth 5
Riyadh 5
Amman 4
Baku 4
Chennai 4
Ciudad del Este 4
Denver 4
Duque de Caxias 4
Fortaleza 4
Lauterbourg 4
London 4
Mexico City 4
Millepini 4
Montreal 4
Nairobi 4
Oklahoma City 4
Orem 4
Pescara 4
Recife 4
San Francisco 4
Thái Bình 4
Thái Nguyên 4
Biên Hòa 3
Bắc Ninh 3
Caxias do Sul 3
Cleveland 3
Cotia 3
Dhaka 3
Hyderabad 3
Manaus 3
Milan 3
Nova Iguaçu 3
Nuremberg 3
Osasco 3
Paris 3
Phoenix 3
Piracicaba 3
Portogruaro 3
Vienna 3
Vitória da Conquista 3
Warsaw 3
Addis Ababa 2
Almaty 2
Ankara 2
Aracaju 2
Atlanta 2
Bangkok 2
Barra Bonita 2
Barra do Piraí 2
Bellaria-Igea Marina 2
Bogotá 2
Boston 2
Bragança Paulista 2
Buon Ma Thuot 2
Bình Phước 2
Cabo Frio 2
Cairo 2
Totale 2.250
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Nome #
The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target 99
Identification of the pyridoxal 5?-phosphate allosteric site in human pyridox(am)ine 5?-phosphate oxidase 92
Study of manganese binding to the ferroxidase centre of human H-type ferritin 77
Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. 76
Iron incorporation into Escherichia coli Dps gives rise to a ferritin-like microcrystalline core 64
Two different crystal forms of sorcin, a penta-EF-hand Ca2+-binding protein 63
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 61
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 58
The Crystal Structure of Giardia duodenalis 14-3-3 in the Apo Form: When Protein Post-Translational Modifications Make the Difference 56
Covid-19: biologia molecolare e infezioni virali 54
AI is a viable alternative to high throughput screening: a 318-target study 53
Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors 51
Reassessment of Protein Stability, DNA Binding, and Protection of Mycobacterium smegmatis Dps. 50
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 50
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming 50
Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa 49
Escherichia coli flavohemoglobin is an efficient alkylhydroperoxide reductase. 48
Silver ion incorporation and nanoparticle formation inside the cavity of Pyrococcus furiosus ferritin: structural and size-distribution analyses. 47
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 47
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design 46
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach 46
A Practical Approach to Protein Crystallography. 45
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 45
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin 43
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 42
Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands 42
The Salmonella enterica ZinT structure, zinc affinity and interaction with the high-affinity Uptake protein ZnuA provide insight into the management of periplasmic zinc 41
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 41
Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing. A study with site-specific mutants 40
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 40
ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds 39
Addition to C-N Bonds 37
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 37
The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site 36
Structural studies on flavohemoglobins. 36
. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs. 36
Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum. 36
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity. 36
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 35
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. 35
Sorcin 34
ITMI20120980 (A1) - PYRROLYL-HYDROXAMATES FOR USE IN THE PREVENTION AND/OR TREATMENT OF BACTERIAL INFECTIONS 34
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target 34
ZnuA, the soluble component of the bacterial Zn(II) ABC transporter, a possible target for novel antibiotics 33
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 33
Protein structure determination by x-ray crystallography 33
Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system. 31
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase 31
Thermosynechococcus elongatus DpsA binds Zn(II) at a unique three histidine-containing ferroxidase center and utilizes O2 as iron oxidant with very high efficiency, unlike the typical Dps proteins 30
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 30
Role of a Conserved Active Site Cation-pi Interaction in Escherichia coli Serine Hydroxymethyltransferase. 29
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme 29
Structural basis of enzymatic S-norcoclaurine biosynthesis. 29
A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca 29
The truncated oxygen-avid hemoglobin from Bacillus subtilis: X-ray structure and ligand binding properties. 28
Metals and metal derivatives in medicine 28
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 28
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures 28
The crystal structure of the sorcin calcium binding domain provides a model of Ca2+-dependent processes in the full-length protein 28
The X-ray structure of the zinc transporter ZnuA from Salmonella enterica discloses a unique triad of zinc-coordinating histidines 27
Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis 27
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 26
Target highlights in CASP14: Analysis of models by structure providers 26
Crystal structure and ligand binding properties of the truncated hemoglobin from Geobacillus stearothermophilus. 25
What is the future of the CNR? 25
Plasticity of secondary structure in the N-terminal region of beta-dystroglycan 24
The Dps protein of Agrobacterium tumefaciens does not bind to DNA but protects it toward oxidative cleavage: x-ray crystal structure, iron binding, and hydroxyl-radical scavenging properties. 24
Plasticity of secondary structure in the N-terminal region of beta-dystroglycan. 24
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress 24
Unusual heme iron-lipid acyl chain coordination in Escherichia coli flavohemoglobin. 23
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 23
The unusual intersubunit ferroxidase center of Listeria innocua Dps is required for hydrogen peroxide detoxification but not for iron uptake. A study with site-specific mutants. 23
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 23
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. 23
Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells 22
New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism 22
The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unexpected geometry of the distal heme pocket 22
Disclosing the Molecular Mechanism of Iron Incorporation in Listeria innocua Dps by EPR Spectroscopy 22
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming 21
Biomimetic Materials Synthesis from Ferritin-Related, Cage-Shaped Proteins 21
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions 21
Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells - A ferritin-like DNA-binding protein of Escherichia coli 21
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 21
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 20
Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins 20
Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation 20
Polyamine metabolism in Leishmania: from arginine to trypanothione 20
The antioxidant Dps protein from the thermophilic cyanobacterium Thermosynechococcus elongatus: an intrinsically stable cage-like structure endowed with enhanced stability 20
Structural basis of Sorcin-mediated calcium-dependent signal transduction. 19
Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter 19
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition 19
Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage 19
Engineered ferritin for lanthanide binding 19
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 18
Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening 18
Iron oxidation and hydrolysis reactions of a novel ferritin from Listeria innocua 18
Targeting polyamine metabolism for finding new drugs against leishmaniasis: A review 18
Iron and proteins for iron storage and detoxification. 18
Trypanothione reductase from Leishmania infantum: cloning, expression, purification, crystallization and preliminary X-ray data analysis. 17
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus--structural basis of substrate recognition. 17
Totale 3.437
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Categoria #
all - tutte 12.424
article - articoli 11.590
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 735
Totale 24.749
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/20246 0 0 0 0 0 0 0 0 1 0 0 5
2024/20251.740 5 7 132 64 340 127 46 110 75 96 394 344
2025/20261.868 145 329 274 477 480 103 60 0 0 0 0 0
Totale 3.614