CNR Institutional Research Information System

COLOMBO, GIORGIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 1.016
AS - Asia 484
EU - Europa 243
OC - Oceania 3
SA - Sud America 3
Totale 1.749
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.009
SG - Singapore 452
IT - Italia 177
FI - Finlandia 12
DE - Germania 10
GB - Regno Unito 10
CN - Cina 8
HK - Hong Kong 6
NL - Olanda 6
LT - Lituania 5
BE - Belgio 4
JP - Giappone 4
CA - Canada 3
LV - Lettonia 3
PA - Panama 3
SE - Svezia 3
BR - Brasile 2
IE - Irlanda 2
KR - Corea 2
NZ - Nuova Zelanda 2
PH - Filippine 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
EE - Estonia 1
FR - Francia 1
IS - Islanda 1
JM - Giamaica 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MY - Malesia 1
PE - Perù 1
PK - Pakistan 1
PT - Portogallo 1
RO - Romania 1
RU - Federazione Russa 1
UA - Ucraina 1
UZ - Uzbekistan 1
Totale 1.749
Salva come PNG Salva come JPEG
Città #
Santa Clara 866
Singapore 245
Milan 68
Brescia 29
Helsinki 12
Alzano Lombardo 10
Los Angeles 10
London 6
Naples 6
Phoenix 6
Hong Kong 5
Padova 5
Bergamo 4
Brussels 4
Cirimido 4
Frankfurt am Main 4
Guangzhou 3
Riga 3
Scandicci 3
Toronto 3
Amsterdam 2
Ancona 2
Ashburn 2
Auckland 2
Bologna 2
Casalecchio di Reno 2
Cavallino 2
Cavaria con Premezzo 2
Dublin 2
Falkenstein 2
Kaunas 2
Manila 2
Pavia 2
Pieve a Nievole 2
Rome 2
Seoul 2
Tokyo 2
Abu Dhabi 1
Afragola 1
Almaty 1
Aversa 1
Baku 1
Bishkek 1
Campinas 1
Casandrino 1
Central 1
Colombo 1
Florence 1
Forest City 1
Islamabad 1
Kuala Lumpur 1
Lima 1
Lisbon 1
Luxembourg 1
Panama City 1
Paris 1
Ponzano Veneto 1
Prague 1
Reston 1
Reykjavik 1
Seattle 1
Tallinn 1
Tashkent 1
Tirana 1
Turin 1
Varese 1
Vargem Grande Paulista 1
Vientiane 1
Yerevan 1
Zurich 1
Totale 1.363
Salva come PNG Salva come JPEG
Nome #
Entropically-Driven Co-assembly of l-Histidine and l-Phenylalanine to Form Supramolecular Materials 39
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions 32
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1 28
Machine Learning of Allosteric Effects: The Analysis of Ligand-Induced Dynamics to Predict Functional Effects in TRAP1 26
The Answer Lies in the Energy: How Simple Atomistic Molecular Dynamics Simulations May Hold the Key to Epitope Prediction on the Fully Glycosylated SARS-CoV-2 Spike Protein 26
Transcription factor protein interactomes reveal genetic determinants in heart disease 25
Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells 24
Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute 23
Recipes for Inducing Cold Denaturation in an Otherwise Stable Protein 23
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 23
Chemical chaperones modulate the formation of metabolite assemblies 21
Simple Model of Protein Energetics to Identify Ab Initio Folding Transitions from All-Atom MD Simulations of Proteins 21
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view 20
SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern 20
Biocompatible graft copolymers from bacterial poly(?-glutamic acid) and poly(lactic acid) 19
HIF1alfa-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia 18
Visualizing the Dynamics of a Protein Folding Machinery: The Mechanism of Asymmetric ATP Processing in Hsp90 and its Implications for Client Remodelling 17
Machine Learning Prediction of Allosteric Drug Activity from Molecular Dynamics 16
Mechanisms of Metabolite Amyloid Formation: Computational Studies for Drug Design against Metabolic Disorders 16
Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data 15
The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation 14
Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE. 14
Integrating Protein Interaction Surface Prediction with a Fragment-Based Drug Design: Automatic Design of New Leads with Fragments on Energy Surfaces 14
Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes 13
BEPPE: an online tool for B and T-cell epitope prediction 13
Crystal Structure of the DFNKF Segment of Human Calcitonin Unveils Aromatic Interactions between Phenylalanines 13
Targeting the mitochondrial chaperone TRAP1: strategies and therapeutic perspectives 13
Tuning the molecular mechanism of hsp70 via a new allosteric network 12
Are amyloid fibrils RNA-traps? A molecular dynamics perspective 12
Exploiting the Burkholderia pseudomallei Acute Phase Antigen BPSL2765 for Structure-Based Epitope Discovery/Design in Structural Vaccinology 12
Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pa13 Epitope 12
Peptides for immunological purposes: design, strategies and applications 12
Understanding Allostery to Design New Drugs 12
Ligand Binding, Unbinding, and Allosteric Effects: Deciphering Small-Molecule Modulation of HSP90 12
The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin ?v?3 12
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro 12
The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2) 12
Protein design: from computer models to artificial intelligence 11
Design of allosteric stimulators of the HSP90 ATPase as novel anticancer leads 11
Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule 11
Computational analysis of dengue virus envelope protein (E) reveals an epitope with flavivirus immunodiagnostic potential in peptide microarrays 11
Novel PARP-1 Inhibitor scaffolds disclosed by a dynamic structure-based pharmacophore approach 11
Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy 11
Enzyme Reactivity Studied by Computer Simulations 11
Designing Chemical Tools with Computational Chemistry 11
Sequence- and Structure-Based Immunoreactive Epitope Discovery for Burkholderia pseudomallei Flagellin 11
Designing Probes for Immunodiagnostics: Structural Insights into an Epitope Targeting Burkholderia Infections 11
Atomistic Simulations of the Mechanisms of the Poorly Catalytic Mitochondrial Chaperone Trap1: Insights into the Effects of Structural Asymmetry on Reactivity 11
Evolving immune-sensing on peptide microarrays: application to Zika virus diagnostics 11
Enzyme reactivity studied by computer simulations 10
Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations 10
DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations. 10
Conformational Behavior of SARS-Cov-2 Spike Protein Variants: Evolutionary Jumps in Sequence Reverberate in Structural Dynamic Differences 10
Peptides for Infectious Diseases: From Probe Design to Diagnostic Microarrays 10
Rational epitope design for protein targeting 10
Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90 10
How the Ligand-Induced Reorganization of Protein Internal Energies Is Coupled to Conformational Events 10
Design of Disruptors of the Hsp90-Cdc37 Interface 10
Structure-based approach for identification of novel phenylboronic acids as serine-?-lactamase inhibitors 10
Structure-based design of a B cell antigen from B. pseudomallei 10
Analyzing dynamic and energetic preorganization to study protein interactions 10
EGFR kinase: what oncogenic mutation can unveil about activation state" XIX International school of pure and applied biophysics on "Theoretical and computational approaches to biophysics 9
Predicting Interaction Sites from the Energetics of Isolated Proteins: A New Approach to Epitope Mapping 9
Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer 9
Identification of Domains in Protein Structures from the Analysis of Intramolecular Interactions 9
Evolving serodiagnostics by rationally designed peptide arrays: The Burkholderia paradigm in Cystic Fibrosis 9
Surface energetics and protein-protein interactions: Analysis and mechanistic implications 9
Inactivation of TEM-1 by avibactam (NXL-104): Insights from quantum mechanics/molecular mechanics metadynamics simulations 9
Synthesis of Functionalized 2-(4-Hydroxyphenyl)-3-methylbenzofuran Allosteric Modulators of Hsp90 Activity 9
Screening Complex Biological Samples with Peptide Microarrays: the Favorable Impact of Probe Orientation via Chemoselective Immobilization Strategies on Clickable Polymeric Coatings. 9
Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors. An integrated strategy for the development of new antiangiogenic compounds 9
Study of the villin headpiece folding dynamics by combining coarse-grained Monte Carlo evolution and all-atom molecular dynamics 9
Chemo-enzymatic synthesis of (: E)-2,3-diaryl-5-styryl- trans -2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90) 9
From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook-associated protein FlgK 9
A structure based pattern recognition on antibodies 9
Combined in silico and experimental approach for drug design: the binding mode of peptidic and non-peptidic inhibitors to hsp90 N-terminal domain. 9
BPSL 1626: Reverse and Structural vaccinology reveal a novel candidate for vaccine design against burkholderia pseudomallei 9
understanding allostery to design new drugs 9
SAGE: A Fast Computational Tool for Linear Epitope Grafting onto a Foreign Protein Scaffold 9
Mechanisms of differential allosteric modulation in homologous proteins: Insights from the analysis of internal dynamics and energetics of PDZ domains 9
Structure and Computation in Immunoreagent Design: From Diagnostics to Vaccines. 9
The role of surface energetics in the formation of protein-protein intercations 9
Enhancing Antibody Serodiagnosis Using a Controlled Peptide Coimmobilization Strategy 9
Computational approaches elucidate the allosteric mechanism of human aromatase inhibition: A novel possible route to small-molecule regulation of cyp450s activities? 8
N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules 8
Structural Determinants of the Unusual Helix Stability of a De Novo Engineered Vascular Endothelial Growth Factor (VEGF) Mimicking Peptide 8
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors 8
The Dynamics of the Folding Machinery 8
The Five-To-Six-Coordination Transition of Ferric Human Serum Heme-Albumin Is Allosterically-Modulated by Ibuprofen and Warfarin: A Combined XAS and MD Study 8
N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease 8
Dynamics-based discovery of allosteric inhibitors: selection of new ligands for the C-terminal domain of Hsp90 8
Synthesis, Structure and Conformation of Partially-Modified Retro and Retro-inverso psi[NHCH(CF3)]Gly-Peptides 8
Folding and mis-folding of peptides and proteins: Insights from molecular simulations 8
Investigating dynamic and energetic determinants of protein nucleic acid recognition: Analysis of the zinc finger zif268-DNA complexes 8
Unveiling the secret of allosteric modulation at trap1 through molecular dynamics studies on a new promising series of inhibitor 8
Cracking the chaperone code through the computational microscope 8
A Multiscale Approach to Characterize the Early Aggregation Steps of the Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35 8
Integrating computational and chemical biology tools in the discovery of antiangiogenic small molecule ligands of FGF2 derived from endogenous inhibitors 8
Enzymatic and inhibition mechanism of human aromatase (CYP19A1) enzyme. A computational perspective from QM/MM and classical molecular dynamics simulations 8
The Interplay between Structural Stability and Plasticity Determines Mutation Profiles and Chaperone Dependence in Protein Kinases 8
Totale 1.252
Salva come PNG Salva come JPEG
Categoria #
all - tutte 8.637
article - articoli 6.392
book - libri 105
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 332
Totale 15.466
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202430 0 0 0 0 0 0 0 0 8 0 6 16
2024/20251.902 13 16 257 155 689 332 70 273 97 0 0 0
Totale 1.932