CNR Institutional Research Information System

COLOMBO, GIORGIO
 Distribuzione geografica
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Continente #
AS - Asia 3.685
NA - Nord America 1.668
SA - Sud America 884
EU - Europa 584
AF - Africa 61
OC - Oceania 4
Totale 6.886
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Nazione #
SG - Singapore 1.704
US - Stati Uniti d'America 1.591
BR - Brasile 724
CN - Cina 636
HK - Hong Kong 482
VN - Vietnam 368
IT - Italia 214
KR - Corea 137
IN - India 126
AR - Argentina 78
NL - Olanda 78
GB - Regno Unito 54
FI - Finlandia 45
DE - Germania 41
BD - Bangladesh 35
JP - Giappone 34
FR - Francia 30
MX - Messico 29
ID - Indonesia 25
ZA - Sudafrica 25
CA - Canada 22
EC - Ecuador 22
IL - Israele 22
IQ - Iraq 17
TR - Turchia 15
CO - Colombia 14
UA - Ucraina 14
AT - Austria 13
PE - Perù 13
PL - Polonia 11
RU - Federazione Russa 11
SA - Arabia Saudita 11
UZ - Uzbekistan 11
VE - Venezuela 11
PY - Paraguay 10
SE - Svezia 10
ES - Italia 9
PK - Pakistan 9
CL - Cile 7
LT - Lituania 7
MA - Marocco 7
JM - Giamaica 6
JO - Giordania 6
PH - Filippine 6
TN - Tunisia 6
AE - Emirati Arabi Uniti 5
BE - Belgio 5
NP - Nepal 5
AZ - Azerbaigian 4
BG - Bulgaria 4
CZ - Repubblica Ceca 4
DZ - Algeria 4
ET - Etiopia 4
IE - Irlanda 4
KE - Kenya 4
KZ - Kazakistan 4
PA - Panama 4
TT - Trinidad e Tobago 4
AL - Albania 3
BH - Bahrain 3
BO - Bolivia 3
EG - Egitto 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
PT - Portogallo 3
RO - Romania 3
TH - Thailandia 3
BB - Barbados 2
BY - Bielorussia 2
CH - Svizzera 2
CR - Costa Rica 2
CV - Capo Verde 2
GT - Guatemala 2
HN - Honduras 2
HU - Ungheria 2
KG - Kirghizistan 2
LB - Libano 2
LK - Sri Lanka 2
MY - Malesia 2
NI - Nicaragua 2
NO - Norvegia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
AM - Armenia 1
AU - Australia 1
BN - Brunei Darussalam 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GE - Georgia 1
GH - Ghana 1
GR - Grecia 1
IR - Iran 1
IS - Islanda 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LY - Libia 1
MK - Macedonia 1
MN - Mongolia 1
MT - Malta 1
Totale 6.877
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Città #
Singapore 1.038
Santa Clara 850
Hong Kong 481
Hefei 312
Beijing 151
Seoul 136
Ho Chi Minh City 129
Hanoi 95
Ashburn 92
San Jose 78
Milan 75
Mumbai 62
São Paulo 61
Dallas 48
Los Angeles 46
Rio de Janeiro 32
Brescia 30
Lappeenranta 24
Minamishinagawa 20
New York 20
Bengaluru 17
Belo Horizonte 14
Brasília 14
Chicago 14
Curitiba 14
Johannesburg 14
Buffalo 13
Da Nang 13
Dhaka 13
Helsinki 13
Ninh Bình 13
Phoenix 13
Frankfurt am Main 12
Denver 11
Alzano Lombardo 10
Haiphong 10
Lima 10
Tashkent 10
Tokyo 10
Warsaw 10
Arese 9
Campinas 9
Guarulhos 9
Guayaquil 9
Houston 9
London 9
Nuremberg 9
Thái Nguyên 9
Atlanta 8
Porto Alegre 8
Recife 8
Ribeirão Preto 8
Riyadh 8
Sorocaba 8
Turku 8
Brooklyn 7
Düsseldorf 7
Goiânia 7
Naples 7
Poplar 7
Quito 7
Stockholm 7
Amman 6
Baghdad 6
Blumenau 6
Chennai 6
Lauterbourg 6
Montreal 6
Orem 6
Pelotas 6
Praia Grande 6
Biên Hòa 5
Boston 5
Brussels 5
Cape Town 5
Guarujá 5
Ha Long 5
Hải Dương 5
Istanbul 5
Manaus 5
Mexico City 5
Padova 5
Phủ Lý 5
Portsmouth 5
Salvador 5
Thái Bình 5
Toronto 5
Vienna 5
Addis Ababa 4
Amsterdam 4
Aracaju 4
Asunción 4
Baku 4
Bergamo 4
Bogotá 4
Campo Grande 4
Caracas 4
Cirimido 4
Colombo 4
Jakarta 4
Totale 4.392
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Nome #
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions 97
The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation 92
Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells 66
Protein design: from computer models to artificial intelligence 65
Entropically-Driven Co-assembly of l-Histidine and l-Phenylalanine to Form Supramolecular Materials 62
PPI predictions and epitope design: what can computational biology tell us? 59
Design of allosteric stimulators of the HSP90 ATPase as novel anticancer leads 59
The Answer Lies in the Energy: How Simple Atomistic Molecular Dynamics Simulations May Hold the Key to Epitope Prediction on the Fully Glycosylated SARS-CoV-2 Spike Protein 59
Chemical chaperones modulate the formation of metabolite assemblies 58
Exploring protein folding and misfolding with molecular simulations 57
Allosteric Modulators of HSP90 and HSP70: Dynamics Meets Function through Structure-Based Drug Design 57
Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity 54
Insights from molecular dynamics simulations for the development of modulators of mitochondrial Hsp90 (Trap1) activity 54
HIF1alfa-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia 54
N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules 53
Recipes for Inducing Cold Denaturation in an Otherwise Stable Protein 53
Computational approaches elucidate the allosteric mechanism of human aromatase inhibition: A novel possible route to small-molecule regulation of cyp450s activities? 52
Visualizing the Dynamics of a Protein Folding Machinery: The Mechanism of Asymmetric ATP Processing in Hsp90 and its Implications for Client Remodelling 52
Machine Learning of Allosteric Effects: The Analysis of Ligand-Induced Dynamics to Predict Functional Effects in TRAP1 52
Designing Molecular Spanners to Throw in the Protein Networks 50
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1 50
Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute 50
Corresponding functional dynamics across the Hsp90 family: insights from a multiscale analysis of MD simulations 48
Transcription factor protein interactomes reveal genetic determinants in heart disease 48
Biocompatible graft copolymers from bacterial poly(?-glutamic acid) and poly(lactic acid) 48
Investigating the mechanism of peptide aggregation: Insights from mixed Monte Carlo-Molecular dynamics simulations 47
Integrating Protein Interaction Surface Prediction with a Fragment-Based Drug Design: Automatic Design of New Leads with Fragments on Energy Surfaces 47
Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule 46
The Interplay between Structural Stability and Plasticity Determines Mutation Profiles and Chaperone Dependence in Protein Kinases 46
The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin ?v?3 46
Are amyloid fibrils RNA-traps? A molecular dynamics perspective 45
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view 44
Simple Model of Protein Energetics to Identify Ab Initio Folding Transitions from All-Atom MD Simulations of Proteins 44
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 44
Molecular Mechanism of Allosteric Communication in Hsp70 Revealed by Molecular Dynamics Simulations 43
Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif 43
Computational analysis of dengue virus envelope protein (E) reveals an epitope with flavivirus immunodiagnostic potential in peptide microarrays 43
Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease 43
Crystal Structure of the DFNKF Segment of Human Calcitonin Unveils Aromatic Interactions between Phenylalanines 43
Tuning the molecular mechanism of hsp70 via a new allosteric network 42
Designing Chemical Tools with Computational Chemistry 42
The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2) 42
Investigating Dynamic and Energetic Determinants of Protein Nucleic Acid Recognition: Analysis of the Zinc Finger Zif268-DNA Complexes 41
Design of New Anticancer Agents 40
Exploiting the Burkholderia pseudomallei Acute Phase Antigen BPSL2765 for Structure-Based Epitope Discovery/Design in Structural Vaccinology 40
Predicting interaction sites from the energetics of isolated proteins: a new approach to epitope mapping 39
How the Ligand-Induced Reorganization of Protein Internal Energies Is Coupled to Conformational Events 39
Assessing the influence of electrostatic schemes on molecular dynamics simulations of secondary structure forming peptides 38
Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90 38
N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease 37
Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE. 37
Mechanisms of Metabolite Amyloid Formation: Computational Studies for Drug Design against Metabolic Disorders 37
Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data 37
Ligand Binding, Unbinding, and Allosteric Effects: Deciphering Small-Molecule Modulation of HSP90 37
DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations. 36
Advancing Molecular Simulations: Merging Physical Models, Experiments, and AI to Tackle Multiscale Complexity 35
The Dynamics of the Folding Machinery 35
Machine Learning Prediction of Allosteric Drug Activity from Molecular Dynamics 35
Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pa13 Epitope 35
Peptides for immunological purposes: design, strategies and applications 35
Enhancing Antibody Serodiagnosis Using a Controlled Peptide Coimmobilization Strategy 35
Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes 34
Surface energetics and protein-protein interactions: Analysis and mechanistic implications 34
Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors. An integrated strategy for the development of new antiangiogenic compounds 34
Enzyme Reactivity Studied by Computer Simulations 34
Design of Disruptors of the Hsp90-Cdc37 Interface 34
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro 34
Designing Probes for Immunodiagnostics: Structural Insights into an Epitope Targeting Burkholderia Infections 34
Modifying protein functions with computational and synthetic chemistry 33
Unveiling the secret of allosteric modulation at trap1 through molecular dynamics studies on a new promising series of inhibitor 33
Chemo-enzymatic synthesis of (: E)-2,3-diaryl-5-styryl- trans -2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90) 33
Energetic and Dynamic Aspects of the Affinity Maturation Process: Characterizing Improved Variants from the Bevacizumab Antibody with Molecular Simulations 33
Structural analysis of a helical peptide unfolding pathway 32
The Subtle Trade-Off between Evolutionary and Energetic Constraints in Protein-Protein Interactions 32
Sequence- and Structure-Based Immunoreactive Epitope Discovery for Burkholderia pseudomallei Flagellin 32
Atomistic Simulations of the Mechanisms of the Poorly Catalytic Mitochondrial Chaperone Trap1: Insights into the Effects of Structural Asymmetry on Reactivity 32
Enzyme reactivity studied by computer simulations 31
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors 31
Conformational Behavior of SARS-Cov-2 Spike Protein Variants: Evolutionary Jumps in Sequence Reverberate in Structural Dynamic Differences 31
Peptides for Infectious Diseases: From Probe Design to Diagnostic Microarrays 31
SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern 31
Structure-based design of a B cell antigen from B. pseudomallei 31
Structure and Computation in Immunoreagent Design: From Diagnostics to Vaccines. 31
Evolving immune-sensing on peptide microarrays: application to Zika virus diagnostics 31
The chaperone TRAP1 as a modulator of the mitochondrial adaptations in cancer cells 30
From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook-associated protein FlgK 30
BEPPE: an online tool for B and T-cell epitope prediction 29
Evolving serodiagnostics by rationally designed peptide arrays: The Burkholderia paradigm in Cystic Fibrosis 29
Targeting the mitochondrial chaperone TRAP1: strategies and therapeutic perspectives 29
Rational epitope design for protein targeting 29
Understanding Allostery to Design New Drugs 29
BPSL 1626: Reverse and Structural vaccinology reveal a novel candidate for vaccine design against burkholderia pseudomallei 29
SAGE: A Fast Computational Tool for Linear Epitope Grafting onto a Foreign Protein Scaffold 29
Novel PARP-1 Inhibitor scaffolds disclosed by a dynamic structure-based pharmacophore approach 28
Screening Complex Biological Samples with Peptide Microarrays: the Favorable Impact of Probe Orientation via Chemoselective Immobilization Strategies on Clickable Polymeric Coatings. 28
Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1 28
An atomistic view of Hsp70 allosteric crosstalk: From the nucleotide to the substrate binding domain and back 28
The role of surface energetics in the formation of protein-protein intercations 28
Analyzing dynamic and energetic preorganization to study protein interactions 28
Structural Determinants of the Unusual Helix Stability of a De Novo Engineered Vascular Endothelial Growth Factor (VEGF) Mimicking Peptide 27
Totale 4.109
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Categoria #
all - tutte 24.796
article - articoli 18.526
book - libri 255
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 763
Totale 44.340
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202430 0 0 0 0 0 0 0 0 8 0 6 16
2024/20253.707 13 16 253 151 670 328 70 272 97 143 916 778
2025/20263.349 244 443 483 847 1.090 141 101 0 0 0 0 0
Totale 7.086