CNR Institutional Research Information System

COLOMBO, GIORGIO
 Distribuzione geografica
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Continente #
AS - Asia 4.447
NA - Nord America 2.131
SA - Sud America 906
EU - Europa 895
AF - Africa 70
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.454
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Nazione #
US - Stati Uniti d'America 2.032
SG - Singapore 2.026
CN - Cina 820
BR - Brasile 740
HK - Hong Kong 512
VN - Vietnam 502
FR - Francia 263
IT - Italia 258
KR - Corea 139
IN - India 138
NL - Olanda 81
AR - Argentina 78
JP - Giappone 77
GB - Regno Unito 56
DE - Germania 55
BD - Bangladesh 52
FI - Finlandia 45
CA - Canada 33
MX - Messico 33
ZA - Sudafrica 28
EC - Ecuador 25
ID - Indonesia 24
IL - Israele 22
IQ - Iraq 22
TR - Turchia 16
UA - Ucraina 16
CO - Colombia 15
AT - Austria 13
PE - Perù 13
RU - Federazione Russa 13
PL - Polonia 12
UZ - Uzbekistan 12
ES - Italia 11
PK - Pakistan 11
SA - Arabia Saudita 11
VE - Venezuela 11
PY - Paraguay 10
SE - Svezia 10
CL - Cile 8
JM - Giamaica 8
JO - Giordania 8
AE - Emirati Arabi Uniti 7
LT - Lituania 7
MA - Marocco 7
PH - Filippine 7
TN - Tunisia 7
IE - Irlanda 6
NP - Nepal 6
BE - Belgio 5
DZ - Algeria 5
ET - Etiopia 5
KE - Kenya 5
KZ - Kazakistan 5
PA - Panama 5
AZ - Azerbaigian 4
BG - Bulgaria 4
BH - Bahrain 4
BO - Bolivia 4
CZ - Repubblica Ceca 4
EG - Egitto 4
LV - Lettonia 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
AL - Albania 3
CR - Costa Rica 3
GT - Guatemala 3
NI - Nicaragua 3
NO - Norvegia 3
NZ - Nuova Zelanda 3
RO - Romania 3
TH - Thailandia 3
BB - Barbados 2
BY - Bielorussia 2
CH - Svizzera 2
CV - Capo Verde 2
HN - Honduras 2
HU - Ungheria 2
KG - Kirghizistan 2
LB - Libano 2
LK - Sri Lanka 2
MY - Malesia 2
QA - Qatar 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
AM - Armenia 1
AO - Angola 1
AU - Australia 1
BN - Brunei Darussalam 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GE - Georgia 1
GH - Ghana 1
GR - Grecia 1
HR - Croazia 1
IR - Iran 1
IS - Islanda 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
Totale 8.439
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Città #
Singapore 1.170
Santa Clara 849
Hong Kong 507
Hefei 312
San Jose 252
Lauterbourg 225
Ho Chi Minh City 177
Beijing 161
Ashburn 140
Seoul 136
Hanoi 130
Los Angeles 84
Milan 81
Mumbai 63
São Paulo 63
Dallas 49
Tokyo 48
New York 41
Brescia 32
Rio de Janeiro 32
Lappeenranta 24
Frankfurt am Main 22
Minamishinagawa 20
Da Nang 18
Bengaluru 17
Buffalo 16
Johannesburg 16
Orem 16
Guangzhou 15
Belo Horizonte 14
Brasília 14
Chicago 14
Curitiba 14
Haiphong 14
Ninh Bình 14
Dhaka 13
Helsinki 13
Phoenix 13
Montreal 12
Brooklyn 11
Chennai 11
Denver 11
Nuremberg 11
Tashkent 11
Warsaw 11
Alzano Lombardo 10
Arese 10
Atlanta 10
Houston 10
Lima 10
London 10
Thái Nguyên 10
Campinas 9
Guarulhos 9
Guayaquil 9
Naples 9
Sorocaba 9
Baghdad 8
Goiânia 8
Porto Alegre 8
Quito 8
Recife 8
Ribeirão Preto 8
Riyadh 8
Turku 8
Amman 7
Amsterdam 7
Düsseldorf 7
Poplar 7
Stockholm 7
Biên Hòa 6
Blumenau 6
Bologna 6
Council Bluffs 6
Elk Grove Village 6
Hải Dương 6
Kyiv 6
Mexico City 6
Praia Grande 6
Rome 6
Salvador 6
Addis Ababa 5
Bergamo 5
Boston 5
Brussels 5
Cape Town 5
Guarujá 5
Ha Long 5
Istanbul 5
Joinville 5
Manaus 5
Nairobi 5
Osaka 5
Padova 5
Pelotas 5
Phủ Lý 5
Portsmouth 5
Quận Một 5
Shenzhen 5
Thái Bình 5
Totale 5.292
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Nome #
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions 106
The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation 98
Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity 83
Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells 77
Protein design: from computer models to artificial intelligence 75
Entropically-Driven Co-assembly of l-Histidine and l-Phenylalanine to Form Supramolecular Materials 75
Chemical chaperones modulate the formation of metabolite assemblies 71
The Answer Lies in the Energy: How Simple Atomistic Molecular Dynamics Simulations May Hold the Key to Epitope Prediction on the Fully Glycosylated SARS-CoV-2 Spike Protein 68
Allosteric Modulators of HSP90 and HSP70: Dynamics Meets Function through Structure-Based Drug Design 66
PPI predictions and epitope design: what can computational biology tell us? 64
Exploring protein folding and misfolding with molecular simulations 64
Design of allosteric stimulators of the HSP90 ATPase as novel anticancer leads 63
Recipes for Inducing Cold Denaturation in an Otherwise Stable Protein 63
Visualizing the Dynamics of a Protein Folding Machinery: The Mechanism of Asymmetric ATP Processing in Hsp90 and its Implications for Client Remodelling 62
N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules 61
Computational approaches elucidate the allosteric mechanism of human aromatase inhibition: A novel possible route to small-molecule regulation of cyp450s activities? 60
Machine Learning of Allosteric Effects: The Analysis of Ligand-Induced Dynamics to Predict Functional Effects in TRAP1 60
Insights from molecular dynamics simulations for the development of modulators of mitochondrial Hsp90 (Trap1) activity 59
Integrating Protein Interaction Surface Prediction with a Fragment-Based Drug Design: Automatic Design of New Leads with Fragments on Energy Surfaces 58
Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute 58
HIF1alfa-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia 57
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view 57
Biocompatible graft copolymers from bacterial poly(?-glutamic acid) and poly(lactic acid) 56
Designing Molecular Spanners to Throw in the Protein Networks 55
Corresponding functional dynamics across the Hsp90 family: insights from a multiscale analysis of MD simulations 54
Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease 54
Computational analysis of dengue virus envelope protein (E) reveals an epitope with flavivirus immunodiagnostic potential in peptide microarrays 53
Transcription factor protein interactomes reveal genetic determinants in heart disease 53
The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin ?v?3 53
Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule 52
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1 52
How the Ligand-Induced Reorganization of Protein Internal Energies Is Coupled to Conformational Events 52
Simple Model of Protein Energetics to Identify Ab Initio Folding Transitions from All-Atom MD Simulations of Proteins 52
Investigating the mechanism of peptide aggregation: Insights from mixed Monte Carlo-Molecular dynamics simulations 51
Are amyloid fibrils RNA-traps? A molecular dynamics perspective 51
Crystal Structure of the DFNKF Segment of Human Calcitonin Unveils Aromatic Interactions between Phenylalanines 51
The Interplay between Structural Stability and Plasticity Determines Mutation Profiles and Chaperone Dependence in Protein Kinases 49
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 49
Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif 48
N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease 48
Molecular Mechanism of Allosteric Communication in Hsp70 Revealed by Molecular Dynamics Simulations 47
Design of New Anticancer Agents 47
Designing Chemical Tools with Computational Chemistry 47
The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2) 47
DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations. 46
Tuning the molecular mechanism of hsp70 via a new allosteric network 46
Peptides for immunological purposes: design, strategies and applications 46
Investigating Dynamic and Energetic Determinants of Protein Nucleic Acid Recognition: Analysis of the Zinc Finger Zif268-DNA Complexes 45
Exploiting the Burkholderia pseudomallei Acute Phase Antigen BPSL2765 for Structure-Based Epitope Discovery/Design in Structural Vaccinology 45
Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90 45
The Five-To-Six-Coordination Transition of Ferric Human Serum Heme-Albumin Is Allosterically-Modulated by Ibuprofen and Warfarin: A Combined XAS and MD Study 44
Predicting interaction sites from the energetics of isolated proteins: a new approach to epitope mapping 43
Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes 43
Conformational Behavior of SARS-Cov-2 Spike Protein Variants: Evolutionary Jumps in Sequence Reverberate in Structural Dynamic Differences 43
Ligand Binding, Unbinding, and Allosteric Effects: Deciphering Small-Molecule Modulation of HSP90 43
Atomistic Simulations of the Mechanisms of the Poorly Catalytic Mitochondrial Chaperone Trap1: Insights into the Effects of Structural Asymmetry on Reactivity 43
Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE. 42
Mechanisms of Metabolite Amyloid Formation: Computational Studies for Drug Design against Metabolic Disorders 42
Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data 42
Assessing the influence of electrostatic schemes on molecular dynamics simulations of secondary structure forming peptides 41
Peptides for Infectious Diseases: From Probe Design to Diagnostic Microarrays 41
Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pa13 Epitope 41
Chemo-enzymatic synthesis of (: E)-2,3-diaryl-5-styryl- trans -2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90) 41
Designing Probes for Immunodiagnostics: Structural Insights into an Epitope Targeting Burkholderia Infections 41
Advancing Molecular Simulations: Merging Physical Models, Experiments, and AI to Tackle Multiscale Complexity 40
The Dynamics of the Folding Machinery 40
Enzyme Reactivity Studied by Computer Simulations 40
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro 40
Enzyme reactivity studied by computer simulations 39
Unveiling the secret of allosteric modulation at trap1 through molecular dynamics studies on a new promising series of inhibitor 39
Energetic and Dynamic Aspects of the Affinity Maturation Process: Characterizing Improved Variants from the Bevacizumab Antibody with Molecular Simulations 39
Enhancing Antibody Serodiagnosis Using a Controlled Peptide Coimmobilization Strategy 39
Structural analysis of a helical peptide unfolding pathway 38
The chaperone TRAP1 as a modulator of the mitochondrial adaptations in cancer cells 38
Machine Learning Prediction of Allosteric Drug Activity from Molecular Dynamics 38
Surface energetics and protein-protein interactions: Analysis and mechanistic implications 38
Design of Disruptors of the Hsp90-Cdc37 Interface 38
Evolving immune-sensing on peptide microarrays: application to Zika virus diagnostics 38
Screening Complex Biological Samples with Peptide Microarrays: the Favorable Impact of Probe Orientation via Chemoselective Immobilization Strategies on Clickable Polymeric Coatings. 37
Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors. An integrated strategy for the development of new antiangiogenic compounds 37
molecular dynamics simulations reveal the mechanisms of allosteric activation of Hsp90 by designed ligands 37
The Subtle Trade-Off between Evolutionary and Energetic Constraints in Protein-Protein Interactions 37
Sequence- and Structure-Based Immunoreactive Epitope Discovery for Burkholderia pseudomallei Flagellin 37
Modifying protein functions with computational and synthetic chemistry 36
Understanding Allostery to Design New Drugs 36
Structure-based design of a B cell antigen from B. pseudomallei 36
Analyzing dynamic and energetic preorganization to study protein interactions 36
Evolving serodiagnostics by rationally designed peptide arrays: The Burkholderia paradigm in Cystic Fibrosis 35
Understanding Complex Mechanisms of Enzyme Reactivity: The Case of Limonene-1,2-Epoxide Hydrolases 35
SAGE: A Fast Computational Tool for Linear Epitope Grafting onto a Foreign Protein Scaffold 35
Structural Determinants of the Unusual Helix Stability of a De Novo Engineered Vascular Endothelial Growth Factor (VEGF) Mimicking Peptide 34
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors 34
Targeting the mitochondrial chaperone TRAP1: strategies and therapeutic perspectives 34
Rational epitope design for protein targeting 34
BPSL 1626: Reverse and Structural vaccinology reveal a novel candidate for vaccine design against burkholderia pseudomallei 34
SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern 34
Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1 34
An atomistic view of Hsp70 allosteric crosstalk: From the nucleotide to the substrate binding domain and back 34
Structure and Computation in Immunoreagent Design: From Diagnostics to Vaccines. 34
The structural intolerance of the PrP ±-fold for palar substitution of the helix-3 methionines 33
Totale 4.806
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Categoria #
all - tutte 29.019
article - articoli 21.678
book - libri 306
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 918
Totale 51.921
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202430 0 0 0 0 0 0 0 0 8 0 6 16
2024/20253.698 13 16 253 150 666 328 70 272 97 142 914 777
2025/20264.929 244 441 480 846 1.088 140 830 246 219 246 149 0
Totale 8.657