CNR Institutional Research Information System

MILARDI, DANILO
 Distribuzione geografica
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Continente #
AS - Asia 3.473
NA - Nord America 1.913
EU - Europa 912
SA - Sud America 686
Continente sconosciuto - Info sul continente non disponibili 247
AF - Africa 57
OC - Oceania 3
Totale 7.291
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Nazione #
US - Stati Uniti d'America 1.799
SG - Singapore 1.587
CN - Cina 701
BR - Brasile 558
VN - Vietnam 390
HK - Hong Kong 353
IT - Italia 237
FR - Francia 219
NL - Olanda 157
KR - Corea 105
JP - Giappone 65
DE - Germania 61
IN - India 59
AR - Argentina 51
CA - Canada 51
GB - Regno Unito 50
FI - Finlandia 49
BD - Bangladesh 44
ID - Indonesia 28
PL - Polonia 28
MX - Messico 23
IL - Israele 20
EC - Ecuador 18
ZA - Sudafrica 18
RU - Federazione Russa 17
SA - Arabia Saudita 17
IQ - Iraq 16
CL - Cile 15
ES - Italia 13
CO - Colombia 12
EG - Egitto 11
UA - Ucraina 11
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
AT - Austria 10
JM - Giamaica 10
SE - Svezia 9
TR - Turchia 9
IE - Irlanda 8
PK - Pakistan 8
PY - Paraguay 8
PE - Perù 7
PH - Filippine 7
CH - Svizzera 6
CZ - Repubblica Ceca 6
KE - Kenya 6
TT - Trinidad e Tobago 6
UZ - Uzbekistan 6
DO - Repubblica Dominicana 5
KZ - Kazakistan 5
MA - Marocco 5
MY - Malesia 5
NP - Nepal 5
RO - Romania 5
TH - Thailandia 5
TN - Tunisia 5
BO - Bolivia 4
BY - Bielorussia 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
AU - Australia 3
AZ - Azerbaigian 3
CR - Costa Rica 3
CY - Cipro 3
DK - Danimarca 3
DZ - Algeria 3
HN - Honduras 3
HR - Croazia 3
IR - Iran 3
JO - Giordania 3
KG - Kirghizistan 3
LB - Libano 3
PA - Panama 3
PT - Portogallo 3
AM - Armenia 2
BG - Bulgaria 2
GT - Guatemala 2
NI - Nicaragua 2
OM - Oman 2
SV - El Salvador 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AO - Angola 1
BH - Bahrain 1
BN - Brunei Darussalam 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
GA - Gabon 1
GE - Georgia 1
GN - Guinea 1
GP - Guadalupe 1
GR - Grecia 1
KW - Kuwait 1
LT - Lituania 1
LV - Lettonia 1
MQ - Martinica 1
MZ - Mozambico 1
NO - Norvegia 1
PR - Porto Rico 1
Totale 7.042
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Città #
Singapore 891
Hong Kong 346
Santa Clara 325
Hefei 265
San Jose 252
Ashburn 207
Dallas 200
Lauterbourg 176
Beijing 146
Ho Chi Minh City 125
Hanoi 110
Seoul 104
Los Angeles 81
São Paulo 49
New York 45
Tokyo 44
Amsterdam 28
Cavallino 26
Frankfurt am Main 25
Buffalo 24
Milan 23
Da Nang 21
Helsinki 21
Warsaw 20
Naples 17
Rio de Janeiro 17
Orem 16
Minamishinagawa 15
Phoenix 15
Turin 15
Denver 14
Haiphong 14
Turku 14
Chennai 13
Lappeenranta 13
Rome 13
Bengaluru 12
Genoa 12
Biên Hòa 10
Charlotte 10
Miami 10
Brasília 9
Campinas 9
Johannesburg 9
Atlanta 8
Baghdad 8
Curitiba 8
Dublin 8
Montreal 8
Nuremberg 8
Phủ Lý 8
Santiago 8
Buenos Aires 7
Chicago 7
Riyadh 7
Stockholm 7
Boston 6
Bắc Ninh 6
Catania 6
Council Bluffs 6
Guayaquil 6
Houston 6
Kingston 6
Las Vegas 6
Nairobi 6
Nha Trang 6
Poplar 6
Recife 6
Seattle 6
Thái Bình 6
Vienna 6
Washington 6
Bauru 5
Belo Horizonte 5
Canoas 5
City of London 5
Columbus 5
Dammam 5
Dhaka 5
Dubai 5
Guangzhou 5
Hangzhou 5
Jakarta 5
Jeddah 5
Mumbai 5
Munich 5
Porto Alegre 5
Quito 5
Salvador 5
San Francisco 5
Tashkent 5
Xi'an 5
Baltimore 4
Bratislava 4
Brooklyn 4
Cairo 4
Caracas 4
Caruaru 4
Casandrino 4
Changsha 4
Totale 4.131
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Nome #
SUMO-2 activity is inhibited by non-covalent interactions with the Aβ peptide: an exploration of potential pathogenic mechanisms in Alzheimer's disease 216
Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug 109
Copper, differently from zinc, affects the conformation, oligomerization state and activity of bradykinin. 101
Amyloid-Mediated Mechanisms of Membrane Disruption 87
The interplay between lipid and A? amyloid homeostasis in Alzheimer's Disease: risk factors and therapeutic opportunities 84
Stretching the chains: the destabilizing impact of Cu2+ and Zn2+ ions on K48-linked diubiquitin 84
A VEGF fragment encompassing residues 10-30 inhibits A1-42 amyloid aggregation and exhibits neuroprotective properties matching the full-length protein 80
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from ?-Amyloid Toxicity 77
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment 73
The double faced role of copper in A beta homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration 72
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells 71
The effect of copper/zinc replacement on the folding free energy of wild type and Cys3Ala/Cys26Ala azurin 70
Metal ions and the clearance of misfolded proteins 70
Structural characterization of the thermal unfolding pathway of human VEGFR1 D2 domain 70
SASDSF2 - K48-linked diubiquitin 70
Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology 70
Exploring the therapeutic potential of Aloin: unraveling neuroprotective and anticancer mechanisms, and strategies for enhanced stability and delivery 70
Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end 69
New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway 69
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States 68
SASDSG2 - K48-linked diubiquitin in the presence of zinc ion 67
. Ubiquitin stability and lys63-linked polyubiquitination site are comprised on copper binding 66
Dipyridamole for tracking amyloidogenic proteins aggregation and enhancing polyubiquitination 66
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges 66
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence 65
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? 63
Targeting immunoproteasome in neurodegeneration: A glance to the future 61
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies 61
Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario 59
Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Ab Aggregates 59
Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution 58
Probing the helical stability in a VEGF-mimetic peptide 57
Editorial 56
Symmetry-breaking transitions in the early steps of protein self-assembly 56
Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition 56
Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles 56
Inorganic Stressors of Ubiquitin 54
SASDSH2 - K48-linked diubiquitin in the presence of copper (II) ion 54
Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions 54
Cracking the Ubiquitin code: CuII and ZnII differently affect K63- and K48-pUb chains elongations 54
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins 53
Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) 53
Insulin Has Multiple Antiamyloidogenic Effects on Human Neuronal Cells 53
beta and gamma-Cyclodextrin dimers: design, characterization and in silico studies to explore the cooperative effect of the cavities 52
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations 51
Tetra-anionic porphyrin mimics protein-protein interactions between regulatory particles and the catalytic core, allosterically activating human 20S proteasome 51
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study 51
Molecular basis of the toxic potential of amyloidogenic peptides: the effect of hIAPP on the liquid-crystalline structure of membranes 50
Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes 50
Extended theoretical analysis of the irreversible thermal unfolding of proteins 50
Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design 49
Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology 49
Ubiquitin binds the amyloid b peptide and interferes with its clearance pathways 49
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 48
Silybins are stereospecific regulators of the 20S proteasome 48
Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins 48
Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging 47
Membrane Interactions and Conformational Preferences of Human and Avian Prion N-terminal tandem repeats: the role of copper(II) ions, pH, and membrane mimicking 46
Electrostatic Map of Proteasome ?-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding 46
Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions 45
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases 43
Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities 43
Investigation on the solid-phase synthesis of silybin prodrugs and their timed-release 43
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides 42
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S 42
The role of Cu(II) ions in the conformational preferences and membrane interaction of human and avian prion proteins N-terminal tandem repeat peptides 41
Synthesis of New Tyrosol-Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability 39
Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins 38
The change of conditions does not affect Ros87 downhill folding mechanism 37
Calorimetric evidences of the different structural role of Glu132 and Glu133 residues in human Superoxide Dismutase 36
Metal ions in neurodegeneration 36
Zinc to cadmium replacement in the prokaryotic zinc-finger domain 36
Modulating Ab aggregation by tyrosol-based ligands: The crucial role of the catechol moiety 35
Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes 35
Site directed mutagenesis of insulin-degrading enzyme allows singling out the molecular basis of peptidase versus E1-like activity: the role of metal ions 34
Environmental effects on conformational diseases. Reactive oxygen species and membrane interactions with prion, amylin and their peptide fragments 34
A combined scanning dilatometric and differential scanning calorimetric study of the thermal unfolding of bovine serum albumin 34
Interaction of prion peptide PrP 180-193 with DPPC model membranes: a thermodynamic study. 33
Deciphering the zinc coordination properties of the prokaryotic zinc finger domain: The solution structure characterization of Ros87 H42A functional mutant 33
Computational comparison of imidazoline association with the I2 binding site in human monoamine oxidases 32
The active role of Ca2+ ions in A?-mediated membrane damage 32
Effect of scan rate and protein concentration on DSC thermograms of Bovine SuperoxideDismutase 32
Functional and structural characterization of the N_terminal peptide of the mitochondrial 32
Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality 32
The Role of Cholesterol in Driving IAPP-Membrane Interactions 31
Environmental effects on a prion's helix II domain: Copper(II) and membrane interactions with PrP180-193 and its analogues 31
The interaction of prion peptide PrP 180-193 with model membranes is modulated by copper: a DSC study 30
The Influence of Metallostasis on Insulin Degrading Enzyme Activity 30
Molecular dynamics: New advances in drug discovery 30
Thermodynamics of azurin folding: the role of the copper ion 30
Interaction of Human Amylin with Phosphatidylcholine and Phosphatydylserine Membranes 30
Copper binding to ubiquitin: an NMR characterization 30
Structural and dynamical determinants of a ?-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein 30
Long range Trp-Trp interaction initiates the folding pathway of a pro-angiogenic ?-hairpin peptide 29
Thermodynamics and kinetics of globular protein thermal unfolding 29
Aspetti termodinamici e cinetici della denaturazione termica dell'Azurina in acqua pesante 28
Inhibition of A? Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry 28
Unveiling the Potential of a New β‐Cyclodextrin‐Suxibuzone Conjugate in Proteasome Regulation 28
Metal binding to Prion protein 28
Interaction of fibrillogenic hIAPP fragments with liquid-crystalline membranes 28
Totale 5.201
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Categoria #
all - tutte 27.190
article - articoli 19.763
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 722
Totale 47.675
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 16 0 12 1
2024/20252.544 11 12 230 117 357 95 25 219 68 150 695 565
2025/20264.405 188 393 612 689 788 167 663 218 212 271 105 99
2026/2027313 215 98 0 0 0 0 0 0 0 0 0 0
Totale 7.291