CNR Institutional Research Information System

MILARDI, DANILO
 Distribuzione geografica
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Continente #
AS - Asia 3.418
NA - Nord America 1.610
EU - Europa 858
SA - Sud America 664
AF - Africa 57
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 6.613
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Nazione #
SG - Singapore 1.576
US - Stati Uniti d'America 1.529
CN - Cina 700
BR - Brasile 550
VN - Vietnam 383
HK - Hong Kong 354
FR - Francia 217
IT - Italia 196
NL - Olanda 152
KR - Corea 105
JP - Giappone 65
DE - Germania 60
IN - India 59
AR - Argentina 50
FI - Finlandia 49
GB - Regno Unito 48
CA - Canada 35
PL - Polonia 27
BD - Bangladesh 23
ID - Indonesia 23
MX - Messico 21
IL - Israele 20
ZA - Sudafrica 18
RU - Federazione Russa 17
IQ - Iraq 16
SA - Arabia Saudita 16
EC - Ecuador 15
CL - Cile 13
ES - Italia 12
EG - Egitto 11
AE - Emirati Arabi Uniti 10
AT - Austria 10
UA - Ucraina 10
CO - Colombia 9
SE - Svezia 9
TR - Turchia 9
IE - Irlanda 8
PK - Pakistan 8
PY - Paraguay 8
JM - Giamaica 7
VE - Venezuela 7
CH - Svizzera 6
CZ - Repubblica Ceca 6
KE - Kenya 6
PE - Perù 6
UZ - Uzbekistan 6
MA - Marocco 5
PH - Filippine 5
RO - Romania 5
TN - Tunisia 5
TT - Trinidad e Tobago 5
BO - Bolivia 4
BY - Bielorussia 4
DO - Repubblica Dominicana 4
KZ - Kazakistan 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
TH - Thailandia 4
AU - Australia 3
AZ - Azerbaigian 3
CY - Cipro 3
DK - Danimarca 3
DZ - Algeria 3
HR - Croazia 3
JO - Giordania 3
KG - Kirghizistan 3
LB - Libano 3
MY - Malesia 3
NP - Nepal 3
PT - Portogallo 3
AM - Armenia 2
BG - Bulgaria 2
HN - Honduras 2
OM - Oman 2
PA - Panama 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AO - Angola 1
BH - Bahrain 1
BN - Brunei Darussalam 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CW - ???statistics.table.value.countryCode.CW??? 1
GA - Gabon 1
GE - Georgia 1
GN - Guinea 1
GP - Guadalupe 1
GR - Grecia 1
GT - Guatemala 1
IR - Iran 1
KW - Kuwait 1
LT - Lituania 1
LV - Lettonia 1
MZ - Mozambico 1
NI - Nicaragua 1
NO - Norvegia 1
PS - Palestinian Territory 1
RS - Serbia 1
SI - Slovenia 1
Totale 6.611
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Città #
Singapore 885
Hong Kong 348
Santa Clara 313
Hefei 265
San Jose 233
Dallas 199
Lauterbourg 175
Beijing 146
Ashburn 145
Ho Chi Minh City 120
Hanoi 109
Seoul 104
Los Angeles 79
São Paulo 49
New York 44
Tokyo 44
Amsterdam 28
Cavallino 26
Frankfurt am Main 25
Buffalo 22
Da Nang 21
Helsinki 21
Warsaw 20
Rio de Janeiro 17
Naples 16
Orem 16
Milan 15
Minamishinagawa 15
Haiphong 14
Turku 14
Chennai 13
Lappeenranta 13
Bengaluru 12
Denver 12
Phoenix 12
Genoa 11
Turin 11
Biên Hòa 10
Campinas 9
Johannesburg 9
Rome 9
Baghdad 8
Brasília 8
Charlotte 8
Curitiba 8
Dublin 8
Nuremberg 8
Phủ Lý 8
Atlanta 7
Buenos Aires 7
Riyadh 7
Stockholm 7
Boston 6
Bắc Ninh 6
Council Bluffs 6
Guayaquil 6
Montreal 6
Nairobi 6
Nha Trang 6
Poplar 6
Recife 6
Santiago 6
Thái Bình 6
Vienna 6
Bauru 5
Belo Horizonte 5
Canoas 5
Catania 5
City of London 5
Dammam 5
Dubai 5
Guangzhou 5
Hangzhou 5
Jakarta 5
Miami 5
Mumbai 5
Munich 5
Porto Alegre 5
Salvador 5
Tashkent 5
Xi'an 5
Bratislava 4
Cairo 4
Caruaru 4
Casandrino 4
Changsha 4
Columbus 4
Dakar 4
Dhaka 4
Düsseldorf 4
Florianópolis 4
Fortaleza 4
Hortolândia 4
Ipatinga 4
Jeddah 4
Karachi 4
Las Vegas 4
Manaus 4
Manchester 4
Mexico City 4
Totale 3.966
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Nome #
SUMO-2 activity is inhibited by non-covalent interactions with the Aβ peptide: an exploration of potential pathogenic mechanisms in Alzheimer's disease 207
Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug 104
Copper, differently from zinc, affects the conformation, oligomerization state and activity of bradykinin. 99
Amyloid-Mediated Mechanisms of Membrane Disruption 84
The interplay between lipid and A? amyloid homeostasis in Alzheimer's Disease: risk factors and therapeutic opportunities 82
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from ?-Amyloid Toxicity 76
A VEGF fragment encompassing residues 10-30 inhibits A1-42 amyloid aggregation and exhibits neuroprotective properties matching the full-length protein 75
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells 71
Stretching the chains: the destabilizing impact of Cu2+ and Zn2+ ions on K48-linked diubiquitin 70
The double faced role of copper in A beta homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration 70
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment 69
SASDSF2 - K48-linked diubiquitin 68
The effect of copper/zinc replacement on the folding free energy of wild type and Cys3Ala/Cys26Ala azurin 67
Metal ions and the clearance of misfolded proteins 67
New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway 67
Structural characterization of the thermal unfolding pathway of human VEGFR1 D2 domain 67
Exploring the therapeutic potential of Aloin: unraveling neuroprotective and anticancer mechanisms, and strategies for enhanced stability and delivery 66
. Ubiquitin stability and lys63-linked polyubiquitination site are comprised on copper binding 65
SASDSG2 - K48-linked diubiquitin in the presence of zinc ion 65
Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end 64
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States 64
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges 64
Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology 63
Dipyridamole for tracking amyloidogenic proteins aggregation and enhancing polyubiquitination 62
Targeting immunoproteasome in neurodegeneration: A glance to the future 60
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies 60
Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution 58
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? 58
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence 57
Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Ab Aggregates 57
Editorial 55
Probing the helical stability in a VEGF-mimetic peptide 55
Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario 55
SASDSH2 - K48-linked diubiquitin in the presence of copper (II) ion 53
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins 52
Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) 52
Insulin Has Multiple Antiamyloidogenic Effects on Human Neuronal Cells 52
Cracking the Ubiquitin code: CuII and ZnII differently affect K63- and K48-pUb chains elongations 51
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations 50
Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition 50
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study 50
Molecular basis of the toxic potential of amyloidogenic peptides: the effect of hIAPP on the liquid-crystalline structure of membranes 49
Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes 49
Extended theoretical analysis of the irreversible thermal unfolding of proteins 49
Inorganic Stressors of Ubiquitin 49
Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design 48
beta and gamma-Cyclodextrin dimers: design, characterization and in silico studies to explore the cooperative effect of the cavities 48
Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles 48
Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions 48
Silybins are stereospecific regulators of the 20S proteasome 47
Tetra-anionic porphyrin mimics protein-protein interactions between regulatory particles and the catalytic core, allosterically activating human 20S proteasome 47
Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology 47
Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins 47
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 46
Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging 46
Membrane Interactions and Conformational Preferences of Human and Avian Prion N-terminal tandem repeats: the role of copper(II) ions, pH, and membrane mimicking 45
Ubiquitin binds the amyloid b peptide and interferes with its clearance pathways 45
Electrostatic Map of Proteasome ?-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding 44
Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions 42
Investigation on the solid-phase synthesis of silybin prodrugs and their timed-release 42
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides 41
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases 39
The role of Cu(II) ions in the conformational preferences and membrane interaction of human and avian prion proteins N-terminal tandem repeat peptides 39
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S 38
Symmetry-breaking transitions in the early steps of protein self-assembly 37
Calorimetric evidences of the different structural role of Glu132 and Glu133 residues in human Superoxide Dismutase 36
Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes 35
Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities 35
Metal ions in neurodegeneration 35
Environmental effects on conformational diseases. Reactive oxygen species and membrane interactions with prion, amylin and their peptide fragments 34
Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins 34
Synthesis of New Tyrosol-Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability 34
A combined scanning dilatometric and differential scanning calorimetric study of the thermal unfolding of bovine serum albumin 33
Site directed mutagenesis of insulin-degrading enzyme allows singling out the molecular basis of peptidase versus E1-like activity: the role of metal ions 32
Functional and structural characterization of the N_terminal peptide of the mitochondrial 32
Zinc to cadmium replacement in the prokaryotic zinc-finger domain 32
Deciphering the zinc coordination properties of the prokaryotic zinc finger domain: The solution structure characterization of Ros87 H42A functional mutant 31
The change of conditions does not affect Ros87 downhill folding mechanism 31
Interaction of prion peptide PrP 180-193 with DPPC model membranes: a thermodynamic study. 30
Computational comparison of imidazoline association with the I2 binding site in human monoamine oxidases 30
The interaction of prion peptide PrP 180-193 with model membranes is modulated by copper: a DSC study 30
Thermodynamics of azurin folding: the role of the copper ion 30
The active role of Ca2+ ions in A?-mediated membrane damage 30
Interaction of Human Amylin with Phosphatidylcholine and Phosphatydylserine Membranes 30
Copper binding to ubiquitin: an NMR characterization 29
Modulating Ab aggregation by tyrosol-based ligands: The crucial role of the catechol moiety 28
Long range Trp-Trp interaction initiates the folding pathway of a pro-angiogenic ?-hairpin peptide 28
Environmental effects on a prion's helix II domain: Copper(II) and membrane interactions with PrP180-193 and its analogues 28
Thermodynamics and kinetics of globular protein thermal unfolding 28
Metal binding to Prion protein 28
Aspetti termodinamici e cinetici della denaturazione termica dell'Azurina in acqua pesante 27
Molecular dynamics: New advances in drug discovery 27
The Role of Cholesterol in Driving IAPP-Membrane Interactions 27
Effect of scan rate and protein concentration on DSC thermograms of Bovine SuperoxideDismutase 27
Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality 27
Structural and dynamical determinants of a ?-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein 27
Interaction of fibrillogenic hIAPP fragments with liquid-crystalline membranes 27
Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study. 26
Solvent isotope effect on Azurin thermal unfolding 26
The inorganic side of Alzheimer's disease 26
Totale 4.911
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Categoria #
all - tutte 23.285
article - articoli 16.980
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 632
Totale 40.897
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 16 0 12 1
2024/20252.536 11 12 230 116 357 95 25 218 68 150 693 561
2025/20264.288 187 392 610 687 786 167 661 217 210 271 100 0
Totale 6.853