D'AMBROSIO, KATIA
D'AMBROSIO, KATIA
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview
2025 D'Ambrosio, Katia; Di Fiore, Anna; Langella, Emma
Multiple Binding Modes of Inhibitors to Human Carbonic Anhydrases: An Update on the Design of Isoform-Specific Modulators of Activity
2025 D'Ambrosio, Katia; Di Fiore, Anna; Alterio, Vincenzo; Langella, Emma; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina
Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain
2022 Akgül, Özlem; Lucarini, Elena; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; D'Ambrosio, Katia; Buonanno, Martina; Monti, Simona Maria; De Simone, Giuseppina; Angeli, Andrea; Supuran, Claudiu T.; Carta, Fabrizio
α-CAs from Photosynthetic Organisms
2022 Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia
The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development
2021 D'Ambrosio, Katia; DI FIORE, Anna; Buonanno, Martina; Kumari, Shikha; Tiwari, Manisha; Supuran Claudiu, T; Mishra Chandra, Bhushan; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
Catechols: a new class of carbonic anhydrase inhibitors
2020 D'Ambrosio, Katia; Carradori, Simone; Cesa, Stefania; Angeli, Andrea; Monti Simona, M; Supuran Claudiu, T; DE SIMONE, Giuseppina
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity
2019 Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna
Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases?
2018 D'Ambrosio, Katia; Supuran Claudiu, T; DE SIMONE, Giuseppina
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one
2018 Supuran Claudiu, T; Alterio, Vincenzo; DI FIORE, Anna; D'Ambrosio, Katia; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
Recent Advances in the Development of New Therapeutic Tools Against Major Parasitic Diseases
2018 DE SIMONE, Giuseppina; D'Ambrosio, Katia
The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior
2018 Buonanno, Martina; DI FIORE, Anna; Langella, Emma; D'Ambrosio, Katia; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases
2016 Langella, Emma; D'Ambrosio, Katia; D'Ascenzio, Melissa; Carradori, Simone; Monti Simona, M; Supuran Claudiu, T; DE SIMONE, Giuseppina
Bacterial Metallo-Enzymes as Drug Targets
2016 Monti Simona, M; D'Ambrosio, Katia; DE SIMONE, Giuseppina
L-Histidinol Dehydrogenase as a New Target for Old Diseases
2016 Monti, Simona M.; De Simone, Giuseppina; D'Ambrosio, Katia
Out of the active site binding pocket for carbonic anhydrase inhibitors
2015 D'Ambrosio, K; Carradori, S; Monti, Sm; Buonanno, M; Secci, D; Vullo, D; Supuran, Ct; De Simone, G
Thermostable carbonic anhydrases in biotechnological applications
2015 Di Fiore, A; Alterio, V; Monti, Sm; De Simone, G; D'Ambrosio, K
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis.
2014 D'Ambrosio, K; Lopez, M; Dathan, Na; Ouahranibettache, S; Köhler, S; Ascione, G; Monti, Sm; Winum, Jy; De Simone, G
Sulfolobus solfataricus thiol redox puzzle: Characterization of an atypical protein disulfide oxidoreductase
2014 Limauro, D; De Simone, G; Pirone, L; Bartolucci, S; D'Ambrosio, K; Pedone, E
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.
2012 D'Ambrosio K; Smaine FZ; Carta F; De Simone G; Winum JY; Supuran CT.
Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms?
2012 Alterio V.; Di Fiore A.; D'Ambrosio K.; Supuran C.T.; De Simone G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview | 1-gen-2025 | D'Ambrosio, Katia; Di Fiore, Anna; Langella, Emma | |
| Multiple Binding Modes of Inhibitors to Human Carbonic Anhydrases: An Update on the Design of Isoform-Specific Modulators of Activity | 1-gen-2025 | D'Ambrosio, Katia; Di Fiore, Anna; Alterio, Vincenzo; Langella, Emma; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina | |
| Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain | 1-gen-2022 | Akgül, Özlem; Lucarini, Elena; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; D'Ambrosio, Katia; Buonanno, Martina; Monti, Simona Maria; De Simone, Giuseppina; Angeli, Andrea; Supuran, Claudiu T.; Carta, Fabrizio | |
| α-CAs from Photosynthetic Organisms | 1-gen-2022 | Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia | |
| The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development | 1-gen-2021 | D'Ambrosio, Katia; DI FIORE, Anna; Buonanno, Martina; Kumari, Shikha; Tiwari, Manisha; Supuran Claudiu, T; Mishra Chandra, Bhushan; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| Catechols: a new class of carbonic anhydrase inhibitors | 1-gen-2020 | D'Ambrosio, Katia; Carradori, Simone; Cesa, Stefania; Angeli, Andrea; Monti Simona, M; Supuran Claudiu, T; DE SIMONE, Giuseppina | |
| Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity | 1-gen-2019 | Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna | |
| Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases? | 1-gen-2018 | D'Ambrosio, Katia; Supuran Claudiu, T; DE SIMONE, Giuseppina | |
| Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one | 1-gen-2018 | Supuran Claudiu, T; Alterio, Vincenzo; DI FIORE, Anna; D'Ambrosio, Katia; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| Recent Advances in the Development of New Therapeutic Tools Against Major Parasitic Diseases | 1-gen-2018 | DE SIMONE, Giuseppina; D'Ambrosio, Katia | |
| The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior | 1-gen-2018 | Buonanno, Martina; DI FIORE, Anna; Langella, Emma; D'Ambrosio, Katia; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases | 1-gen-2016 | Langella, Emma; D'Ambrosio, Katia; D'Ascenzio, Melissa; Carradori, Simone; Monti Simona, M; Supuran Claudiu, T; DE SIMONE, Giuseppina | |
| Bacterial Metallo-Enzymes as Drug Targets | 1-gen-2016 | Monti Simona, M; D'Ambrosio, Katia; DE SIMONE, Giuseppina | |
| L-Histidinol Dehydrogenase as a New Target for Old Diseases | 1-gen-2016 | Monti, Simona M.; De Simone, Giuseppina; D'Ambrosio, Katia | |
| Out of the active site binding pocket for carbonic anhydrase inhibitors | 1-gen-2015 | D'Ambrosio, K; Carradori, S; Monti, Sm; Buonanno, M; Secci, D; Vullo, D; Supuran, Ct; De Simone, G | |
| Thermostable carbonic anhydrases in biotechnological applications | 1-gen-2015 | Di Fiore, A; Alterio, V; Monti, Sm; De Simone, G; D'Ambrosio, K | |
| Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis. | 1-gen-2014 | D'Ambrosio, K; Lopez, M; Dathan, Na; Ouahranibettache, S; Köhler, S; Ascione, G; Monti, Sm; Winum, Jy; De Simone, G | |
| Sulfolobus solfataricus thiol redox puzzle: Characterization of an atypical protein disulfide oxidoreductase | 1-gen-2014 | Limauro, D; De Simone, G; Pirone, L; Bartolucci, S; D'Ambrosio, K; Pedone, E | |
| Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups. | 1-gen-2012 | D'Ambrosio K; Smaine FZ; Carta F; De Simone G; Winum JY; Supuran CT. | |
| Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? | 1-gen-2012 | Alterio V.; Di Fiore A.; D'Ambrosio K.; Supuran C.T.; De Simone G. |