MARI, ANDREA
MARI, ANDREA
Istituto di Neuroscienze - IN -
At any Level of Adiposity, Relatively Elevated Leptin Concentrations Are Associated With Decreased Insulin Sensitivity
2024 Chiriaco, M.; Nesti, L.; Flyvbjerg, A.; Golay, A.; Nazare, J. -A.; Anderwald, C. -H.; Mitrakou, A.; Bizzotto, R.; Mari, A.; Natali, A.
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study
2024 Sharma, S.; Dong, Q.; Haid, M.; Adam, J.; Bizzotto, R.; Fernandez-Tajes, J. J.; Jones, A. G.; Tura, A.; Artati, A.; Prehn, C.; Kastenmüller, G.; Koivula, R. W.; Franks, P. W.; Walker, M.; Forgie, I. M.; Giordano, G.; Pavo, I.; Ruetten, H.; Dermitzakis, M.; Mccarthy, M. I.; Pedersen, O.; Schwenk, J. M.; Tsirigos, K. D.; De Masi, F.; Brunak, S.; Viñuela, A.; Mari, A.; Mcdonald, T. J.; Kokkola, T.; Adamski, J.; Pearson, E. R.; Grallert, H.
The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study
2024 Eriksen, Rebeca; White, Margaret C; Dawed, Adem Y; Perez, Isabel Garcia; Posma, Joram M; Haid, Mark; Sharma, Sapna; Prehn, Cornelia; Thomas, E Louise; Koivula, Robert W; Bizzotto, Roberto; Mari, Andrea; Giordano, Giuseppe N; Pavo, Imre; Schwenk, Jochen M; De Masi, Federico; Tsirigos, Konstantinos D; Brunak, Søren; Viñuela, Ana; Mahajan, Anubha; Mcdonald, Timothy J; Kokkola, Tarja; Rutters, Femke; Beulens, Joline; Muilwijk, Mirthe; Blom, Marieke; Elders, Petra; Hansen, Tue H; Fernandez-Tajes, Juan; Jones, Angus; Jennison, Chris; Walker, Mark; Mccarthy, Mark I; Pedersen, Oluf; Ruetten, Hartmut; Forgie, Ian; Holst, Jens J; Thomsen, Henrik S; Ridderstråle, Martin; Bell, Jimmy D; Adamski, Jerzy; Franks, Paul W; Hansen, Torben; Holmes, Elaine; Frost, Gary; Pearson, Ewan R
Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models (Nature Biotechnology, (2023), 41, 3, (399-408), 10.1038/s41587-022-01520-x)
2023 Allesoe, R. L.; Lundgaard, A. T.; Hernandez Medina, R.; Aguayo-Orozco, A.; Johansen, J.; Nissen, J. N.; Brorsson, C.; Mazzoni, G.; Niu, L.; Biel, J. H.; Leal Rodriguez, C.; Brasas, V.; Webel, H.; Benros, M. E.; Pedersen, A. G.; Chmura, P. J.; Jacobsen, U. P.; Mari, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J. F.; Sharma, S.; Haid, M.; Hong, M. -G.; Musholt, P. B.; De Masi, F.; Vogt, J.; Pedersen, H. K.; Gudmundsdottir, V.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, E. L.; Frost, G.; Thomsen, H.; Hansen, E.; Hansen, T. H.; Vestergaard, H.; Muilwijk, M.; Blom, M. T.; 't Hart, L. M.; Pattou, F.; Raverdy, V.; Brage, S.; Kokkola, T.; Heggie, A.; Mcevoy, D.; Mourby, M.; Kaye, J.; Hattersley, A.; Mcdonald, T.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G. N.; Pavo, I.; Ruetten, H.; Pedersen, O.; Hansen, T.; Dermitzakis, E.; Franks, P. W.; Schwenk, J. M.; Adamski, J.; Mccarthy, M. I.; Pearson, E.; Banasik, K.; Rasmussen, S.; Brunak, S.; Froguel, P.; Thomas, C. E.; Haussler, R.; Beulens, J.; Rutters, F.; Nijpels, G.; van Oort, S.; Groeneveld, L.; Elders, P.; Giorgino, T.; Rodriquez, M.; Nice, R.; Perry, M.; Bianzano, S.; Graefe-Mody, U.; Hennige, A.; Grempler, R.; Baum, P.; Staerfeldt, H. -H.; Shah, N.; Teare, H.; Ehrhardt, B.; Tillner, J.; Dings, C.; Lehr, T.; Scherer, N.; Sihinevich, I.; Cabrelli, L.; Loftus, H.; Bizzotto, R.; Tura, A.; Dekkers, K.; van Leeuwen, N.; Groop, L.; Slieker, R.; Ramisch, A.; Jennison, C.; Mcvittie, I.; Frau, F.; Steckel-Hamann, B.; Adragni, K.; Thomas, M.; Pasdar, N. A.; Fitipaldi, H.; Kurbasic, A.; Mutie, P.; Pomares-Millan, H.; Bonnefond, A.; Canouil, M.; Caiazzo, R.; Verkindt, H.; Holl, R.; Kuulasmaa, T.; Deshmukh, H.; Cederberg, H.; Laakso, M.; Vangipurapu, J.; Dale, M.; Thorand, B.; Nicolay, C.; Fritsche, A.; Hill, A.; Hudson, M.; Thorne, C.; Allin, K.; Arumugam, M.; Jonsson, A.; Engelbrechtsen, L.; Forman, A.; Dutta, A.; Sondertoft, N.; Fan, Y.; Gough, S.; Robertson, N.; Mcrobert, N.; Wesolowska-Andersen, A.; Brown, A.; Davtian, D.; Dawed, A.; Donnelly, L.; Palmer, C.; White, M.; Ferrer, J.; Whitcher, B.; Artati, A.; Prehn, C.; Adam, J.; Grallert, H.; Gupta, R.; Sackett, P. W.; Nilsson, B.; Tsirigos, K.; Eriksen, R.; Jablonka, B.; Uhlen, M.; Gassenhuber, J.; Baltauss, T.; de Preville, N.; Klintenberg, M.; Abdalla, M.
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits
2023 Brown, A. A.; Fernandez-Tajes, J. J.; Hong, M. -G.; Brorsson, C. A.; Koivula, R. W.; Davtian, D.; Dupuis, T.; Sartori, A.; Michalettou, T. -D.; Forgie, I. M.; Adam, J.; Allin, K. H.; Caiazzo, R.; Cederberg, H.; De Masi, F.; Elders, P. J. M.; Giordano, G. N.; Haid, M.; Hansen, T.; Hansen, T. H.; Hattersley, A. T.; Heggie, A. J.; Howald, C.; Jones, A. G.; Kokkola, T.; Laakso, M.; Mahajan, A.; Mari, A.; Mcdonald, T. J.; Mcevoy, D.; Mourby, M.; Musholt, P. B.; Nilsson, B.; Pattou, F.; Penet, D.; Raverdy, V.; Ridderstrale, M.; Romano, L.; Rutters, F.; Sharma, S.; Teare, H.; 't Hart, L.; Tsirigos, K. D.; Vangipurapu, J.; Vestergaard, H.; Brunak, S.; Franks, P. W.; Frost, G.; Grallert, H.; Jablonka, B.; Mccarthy, M. I.; Pavo, I.; Pedersen, O.; Ruetten, H.; Walker, M.; Adragni, K.; Allesoe, R. L. L.; Artati, A. A.; Arumugam, M.; Atabaki-Pasdar, N.; Baltauss, T.; Banasik, K.; Barnett, A. L.; Baum, P.; Bell, J. D.; Beulens, J. W.; Bianzano, S. B.; Bizzotto, R.; Bonnefond, A.; Cabrelli, L.; Dale, M.; Dawed, A. Y.; de Preville, N.; Dekkers, K. F.; Deshmukh, H. A.; Dings, C.; Donnelly, L.; Dutta, A.; Ehrhardt, B.; Engelbrechtsen, L.; Eriksen, R.; Fan, Y.; Ferrer, J.; Fitipaldi, H.; Forman, A.; Fritsche, A.; Froguel, P.; Gassenhuber, J.; Gough, S.; Graefe-Mody, U.; Grempler, R.; Groeneveld, L.; Groop, L.; Gudmundsdottir, V.; Gupta, R.; Hennige, A. M. H.; Hill, A. V.; Holl, R. W.; Hudson, M.; Jacobsen, U. P.; Jennison, C.; Johansen, J.; Jonsson, A.; Karaderi, T.; Kaye, J.; Kennedy, G.; Klintenberg, M.; Kuulasmaa, T.; Lehr, T.; Loftus, H.; Lundgaard, A. T. T.; Mazzoni, G.; Mcrobert, N.; Mcvittie, I.; Nice, R.; Nicolay, C.; Nijpels, G.; Palmer, C. N.; Pedersen, H. K.; Perry, M. H.; Pomares-Millan, H.; Prehn, C. P.; Ramisch, A.; Rasmussen, S.; Robertson, N.; Rodriquez, M.; Sackett, P.; Scherer, N.; Shah, N.; Sihinevich, I.; Slieker, R. C.; Sondertoft, N. B.; Steckel-Hamann, B.; Thomas, M. K.; Thomas, C. E. E.; Thomas, E. L. L.; Thorand, B.; Thorne, C. E.; Tillner, J.; Tura, A.; Uhlen, M.; van Leeuwen, N.; van Oort, S.; Verkindt, H.; Vogt, J.; Wad Sackett, P. W.; Wesolowska-Andersen, A.; Whitcher, B.; White, M. W.; Adamski, J.; Schwenk, J. M.; Pearson, E. R.; Dermitzakis, E. T.; Vinuela, A.
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials
2023 Dawed Adem, Y; Mari, Andrea; Brown, Andrew; McDonald Timothy, J; Li, Lin; Wang, Shuaicheng; Hong Mun, Gwan; Sharma, Sapna; Robertson Neil, R; Mahajan, Anubha; Wang, Xuan; Walker, Mark; Gough, Stephen; Hart Leen, M'T; Zhou, Kaixin; Forgie, Ian; Ruetten, Hartmut; Pavo, Imre; Bhatnagar, Pallav; Jones Angus, G; Pearson Ewan, R; 't Hart, L M; Abdalla, M; Adam, J; Adamski, J; Adragni, K; Allin, K H; Arumugam, M; Atabaki Pasdar, N; Baltauss, T; Banasik, K B; Baum, P; Bell, J D; Bergstrom, M; Beulens, J W; Bianzano, S; Bizzotto, R; Bonneford, A; Brorsson, C AB; Brown, A A; Brunak, S B; Cabrelli, L; Caiazzo, R; Canouil, M; Dale, M; Davtian, D; Dawed Adem, Y; De Masi, F M; de Preville, N; Dekkers, K F; Dermitzakis, E T; Deshmukh, H A; Dings, C; Donnelly, L; Dutta, A; Ehrhardt, B; Elders, P JM; Engel Thomas, C ET; Engelbrechtsen, L; Eriksen, R G; Eriksen, R E; Fan, Y; Fernandez, J; Ferrer, J; Fitipaldi, H; Forgie, Ian; Forman, A; Franks, P W; Frau, F; Fritsche, A; Froguel, P; Frost, G; Gassenhuber, J; Giordano, G N; Giorgino, T; Gough, S; Graefemody, U; Grallert, H; Grempler, R; Groeneveld, L; Groop, L; Gudmundsdóttir, V G; Gupta, R G; Haid, M; Hansen, T; Hansen, T H; Hattersley, A T; Haussler, R S; Heggie, A J; Hennige, A M; Hill, A V; Holl, R W; Hong, M G; Hudson, M; Jablonka, B; Jennison, C; Jiao, J; Johansen, J J; Jones, A G; Jonsson, A
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
2022 Wesolowska-Andersen, A.; Brorsson, C. A.; Bizzotto, R.; Mari, A.; Tura, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J. F.; Sharma, S.; Haid, M.; Prehn, C.; Artati, A.; Hong, M. -G.; Musholt, P. B.; Kurbasic, A.; De Masi, F.; Tsirigos, K.; Pedersen, H. K.; Gudmundsdottir, V.; Thomas, C. E.; Banasik, K.; Jennison, C.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, L.; Frost, G.; Thomsen, H.; Allin, K.; Hansen, T. H.; Vestergaard, H.; Hansen, T.; Rutters, F.; Elders, P.; T'Hart, L.; Bonnefond, A.; Canouil, M.; Brage, S.; Kokkola, T.; Heggie, A.; Mcevoy, D.; Hattersley, A.; Mcdonald, T.; Teare, H.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G. N.; Froguel, P.; Pavo, I.; Ruetten, H.; Pedersen, O.; Dermitzakis, E.; Franks, P. W.; Schwenk, J. M.; Adamski, J.; Pearson, E.; Mccarthy, M. I.; Brunak, S.
Lipid-induced glucose intolerance is driven by impaired glucose kinetics and insulin metabolism in healthy individuals
2022 Trico, D.; Mengozzi, A.; Baldi, S.; Bizzotto, R.; Olaniru, O.; Toczyska, K.; Huang, G. C.; Seghieri, M.; Frascerra, S.; Amiel, S. A.; Persaud, S.; Jones, P.; Mari, A.; Natali, A.
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
2021 Deshmukh Harshal, A; Madsen Anne, Lundager; Vinuela, Ana; Have Christian, Theil; Grarup, Niels; Tura, Andrea; Mahajan, Anubha; Heggie Alison, J; Koivula Robert, W; De Masi, Federico; Tsirigos Konstantinos, K; Linneberg, Allan; Drivsholm, Thomas; Pedersen, Oluf; Sorensen Thorkild, I A; Astrup, Arne; Gjesing Anette, A P; Pavo, Imre; Wood Andrew, R; Ruetten, Hartmut; Jones Angus, G; Koopman Anitra, D M; Cederberg, Henna; Rutters, Femke; Ridderstrale, Martin; Laakso, Markku; McCarthy Mark, I; Frayling Tim, M; Ferrannini, Eleuterio; Franks Paul, W; Pearson Ewan, R; Mari, Andrea; Hansen, Torben; Walker, Mark
Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
2021 Gitelman, Se; Bundy, Bn; Ferrannini, E; Lim, N; Blanchfield, Jl; Dimeglio, La; Felner, Ei; Gaglia, Jl; Gottlieb, Pa; Long, Sa; Mari, A; Mirmira, Rg; Raskin, P; Sanda, S; Tsalikian, E; Wentworth, Jm; Willi, Sm; Krischer, Jp; Bluestone, Ja; Barr, M; Buchanan, J; Cabbage, J; Coleman, P; De La Vega, M; Evansmolina, C; Ferrara, C; Healy, F; Higgins, L; Hildinger, M; Jenkins, M; Kayton Bryant, N; Kinderman, A; Koshy, N; Kost, B; Krishfield, S; Kucheruk, O; Lindsley, K; Mantravadi, M; Mesfin, S; Michels, A; Migre, Me; Minnock, P; Mohammednur, E; Nelson, J; Nursing, A; O'Donnell, R; Olivos, D; Parker, M; Redl, L; Reed, N; Resnick, B; Sayre, P; Serti, E; Sims, E; Smith, K; Soppe, C; Stuart, F; Szubowicz, S; Tansey, M; Terrell, J; Tersey, S; Torok, C; Watson, K; Wesch, R; Willi, S; Woerner, S
New insights on the interactions between insulin clearance and the main glucose homeostasis mechanisms
2021 Bizzotto, R; Trico, D; Natali, A; Gastaldelli, A; Muscelli, E; De Fronzo, Ra; Arslanian, S; Ferrannini, E; Mari, A
Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans
2021 Cinti F.; Mezza T.; Severi I.; Suleiman M.; Cefalo C.M.A.; Sorice G.P.; Moffa S.; Impronta F.; Quero G.; Alfieri S.; Mari A.; Pontecorvi A.; Marselli L.; Cinti S.; Marchetti P.; Giaccari A.
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
2021 Bizzotto, Roberto; Jennison, Christopher; Jones, Angus G.; Kurbasic, Azra; Tura, Andrea; Kennedy, Gwen; Bell, Jimmy D.; Thomas, E. Louise; Frost, Gary; Eriksen, Rebeca; Koivula, Robert W.; Brage, Soren; Kaye, Jane; Hattersley, Andrew T.; Heggie, Alison; McEvoy, Donna; 't Hart, Leen M.; Beulens, Joline W.; Elders, Petra; Musholt, Petra B.; Ridderstrale, Martin; Hansen, Tue H.; Allin, Kristine H.; Hansen, Torben; Vestergaard, Henrik; Lundgaard, Agnete T.; Thomsen, Henrik S.; De Masi, Federico; Tsirigos, Konstantinos D.; Brunak, Soren; Vinuela, Ana; Mahajan, Anubha; McDonald, Timothy J.; Kokkola, Tarja; Forgie, Ian M.; Giordano, Giuseppe N.; Pavo, Imre; Ruetten, Hartmut; Dermitzakis, Emmanouil; McCarthy, Mark I.; Pedersen, Oluf; Schwenk, Jochen M.; Adamski, Jerzy; Franks, Paul W.; Walker, Mark; Pearson, Ewan R.; Mari, Andrea
Association of artificially sweetened and sugar-sweetened soft drinks with ?-cell function, insulin sensitivity, and type 2 diabetes: the Maastricht Study
2020 den Biggelaar L.J.C.J.; Sep S.J.S.; Mari A.; Ferrannini E.; van Dongen M.C.J.M.; Wijckmans N.E.G.; Schram M.T.; van der Kallen C.J.; Schaper N.; Henry R.M.A.; van Greevenbroek M.M.; Stehouwer C.D.A.; Eussen S.J.P.M.
Beta-cells in youth with impaired glucose tolerance or early type 2 diabetes secrete more insulin and are more responsive than in adults
2020 Utzschneider, Km; Tripputi, Mt; Kozedub, A; Mather, Kj; Nadeau, Kj; Edelstein, Sl; Hannon, Ts; Arslanian, Sa; Creegreen, M; Buchanan, Ta; Caprio, S; Mari, A
Brain substrate metabolism and ß-cell function in humans: A positron emission tomography study
2020 Rebelos, E; Mari, A; Bucci, M; Honka, Mj; Hannukainen, Jc; Virtanen, Ka; Hirvonen, J; Nummenmaa, L; Heni, M; Iozzo, P; Ferrannini, E; Nuutila, P
Circulating palmitoleic acid is an independent determinant of insulin sensitivity, beta cell function and glucose tolerance in non-diabetic individuals: a longitudinal analysis
2020 Trico D.; Mengozzi A.; Nesti L.; Hatunic M.; Gabriel Sanchez R.; Konrad T.; Lalic K.; Lalic N.M.; Mari A.; Natali A.
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study
2020 Eriksen R.; Perez I.G.; Posma J.M.; Haid M.; Sharma S.; Prehn C.; Thomas L.E.; Koivula R.W.; Bizzotto R.; Mari A.; Giordano G.N.; Pavo I.; Schwenk J.M.; De Masi F.; Tsirigos K.D.; Brunak S.; Vinuela A.; Mahajan A.; McDonald T.J.; Kokkola T.; Rutter F.; Teare H.; Hansen T.H.; Fernandez J.; Jones A.; Jennison C.; Walker M.; McCarthy M.I.; Pedersen O.; Ruetten H.; Forgie I.; Bell J.D.; Pearson E.R.; Franks P.W.; Adamski J.; Holmes E.; Frost G.
Different mechanisms of GIP and GLP-1 action explain their different therapeutic efficacy in type 2 diabetes
2020 Grespan, Eleonora; Giorgino, Toni; Natali, Andrea; Ferrannini, Eleuterio; Mari, Andrea
Disruption of fasting and post-load glucose homeostasis are largely independent and sustained by distinct and early major beta-cell function defects: a cross-sectional and longitudinal analysis of the Relationship between Insulin Sensitivity and Cardiovascular risk (RISC) study cohort
2020 Mengozzi, A; Trico, D; Nesti, L; Petrie, J; Hojlund, K; Mitrakou, A; Krebs, M; Mari, A; Natali, A
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| At any Level of Adiposity, Relatively Elevated Leptin Concentrations Are Associated With Decreased Insulin Sensitivity | 1-gen-2024 | Chiriaco, M.; Nesti, L.; Flyvbjerg, A.; Golay, A.; Nazare, J. -A.; Anderwald, C. -H.; Mitrakou, A.; Bizzotto, R.; Mari, A.; Natali, A. | |
| Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study | 1-gen-2024 | Sharma, S.; Dong, Q.; Haid, M.; Adam, J.; Bizzotto, R.; Fernandez-Tajes, J. J.; Jones, A. G.; Tura, A.; Artati, A.; Prehn, C.; Kastenmüller, G.; Koivula, R. W.; Franks, P. W.; Walker, M.; Forgie, I. M.; Giordano, G.; Pavo, I.; Ruetten, H.; Dermitzakis, M.; Mccarthy, M. I.; Pedersen, O.; Schwenk, J. M.; Tsirigos, K. D.; De Masi, F.; Brunak, S.; Viñuela, A.; Mari, A.; Mcdonald, T. J.; Kokkola, T.; Adamski, J.; Pearson, E. R.; Grallert, H. | |
| The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study | 1-gen-2024 | Eriksen, Rebeca; White, Margaret C; Dawed, Adem Y; Perez, Isabel Garcia; Posma, Joram M; Haid, Mark; Sharma, Sapna; Prehn, Cornelia; Thomas, E Louise; Koivula, Robert W; Bizzotto, Roberto; Mari, Andrea; Giordano, Giuseppe N; Pavo, Imre; Schwenk, Jochen M; De Masi, Federico; Tsirigos, Konstantinos D; Brunak, Søren; Viñuela, Ana; Mahajan, Anubha; Mcdonald, Timothy J; Kokkola, Tarja; Rutters, Femke; Beulens, Joline; Muilwijk, Mirthe; Blom, Marieke; Elders, Petra; Hansen, Tue H; Fernandez-Tajes, Juan; Jones, Angus; Jennison, Chris; Walker, Mark; Mccarthy, Mark I; Pedersen, Oluf; Ruetten, Hartmut; Forgie, Ian; Holst, Jens J; Thomsen, Henrik S; Ridderstråle, Martin; Bell, Jimmy D; Adamski, Jerzy; Franks, Paul W; Hansen, Torben; Holmes, Elaine; Frost, Gary; Pearson, Ewan R | |
| Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models (Nature Biotechnology, (2023), 41, 3, (399-408), 10.1038/s41587-022-01520-x) | 1-gen-2023 | Allesoe, R. L.; Lundgaard, A. T.; Hernandez Medina, R.; Aguayo-Orozco, A.; Johansen, J.; Nissen, J. N.; Brorsson, C.; Mazzoni, G.; Niu, L.; Biel, J. H.; Leal Rodriguez, C.; Brasas, V.; Webel, H.; Benros, M. E.; Pedersen, A. G.; Chmura, P. J.; Jacobsen, U. P.; Mari, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J. F.; Sharma, S.; Haid, M.; Hong, M. -G.; Musholt, P. B.; De Masi, F.; Vogt, J.; Pedersen, H. K.; Gudmundsdottir, V.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, E. L.; Frost, G.; Thomsen, H.; Hansen, E.; Hansen, T. H.; Vestergaard, H.; Muilwijk, M.; Blom, M. T.; 't Hart, L. M.; Pattou, F.; Raverdy, V.; Brage, S.; Kokkola, T.; Heggie, A.; Mcevoy, D.; Mourby, M.; Kaye, J.; Hattersley, A.; Mcdonald, T.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G. N.; Pavo, I.; Ruetten, H.; Pedersen, O.; Hansen, T.; Dermitzakis, E.; Franks, P. W.; Schwenk, J. M.; Adamski, J.; Mccarthy, M. I.; Pearson, E.; Banasik, K.; Rasmussen, S.; Brunak, S.; Froguel, P.; Thomas, C. E.; Haussler, R.; Beulens, J.; Rutters, F.; Nijpels, G.; van Oort, S.; Groeneveld, L.; Elders, P.; Giorgino, T.; Rodriquez, M.; Nice, R.; Perry, M.; Bianzano, S.; Graefe-Mody, U.; Hennige, A.; Grempler, R.; Baum, P.; Staerfeldt, H. -H.; Shah, N.; Teare, H.; Ehrhardt, B.; Tillner, J.; Dings, C.; Lehr, T.; Scherer, N.; Sihinevich, I.; Cabrelli, L.; Loftus, H.; Bizzotto, R.; Tura, A.; Dekkers, K.; van Leeuwen, N.; Groop, L.; Slieker, R.; Ramisch, A.; Jennison, C.; Mcvittie, I.; Frau, F.; Steckel-Hamann, B.; Adragni, K.; Thomas, M.; Pasdar, N. A.; Fitipaldi, H.; Kurbasic, A.; Mutie, P.; Pomares-Millan, H.; Bonnefond, A.; Canouil, M.; Caiazzo, R.; Verkindt, H.; Holl, R.; Kuulasmaa, T.; Deshmukh, H.; Cederberg, H.; Laakso, M.; Vangipurapu, J.; Dale, M.; Thorand, B.; Nicolay, C.; Fritsche, A.; Hill, A.; Hudson, M.; Thorne, C.; Allin, K.; Arumugam, M.; Jonsson, A.; Engelbrechtsen, L.; Forman, A.; Dutta, A.; Sondertoft, N.; Fan, Y.; Gough, S.; Robertson, N.; Mcrobert, N.; Wesolowska-Andersen, A.; Brown, A.; Davtian, D.; Dawed, A.; Donnelly, L.; Palmer, C.; White, M.; Ferrer, J.; Whitcher, B.; Artati, A.; Prehn, C.; Adam, J.; Grallert, H.; Gupta, R.; Sackett, P. W.; Nilsson, B.; Tsirigos, K.; Eriksen, R.; Jablonka, B.; Uhlen, M.; Gassenhuber, J.; Baltauss, T.; de Preville, N.; Klintenberg, M.; Abdalla, M. | |
| Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits | 1-gen-2023 | Brown, A. A.; Fernandez-Tajes, J. J.; Hong, M. -G.; Brorsson, C. A.; Koivula, R. W.; Davtian, D.; Dupuis, T.; Sartori, A.; Michalettou, T. -D.; Forgie, I. M.; Adam, J.; Allin, K. H.; Caiazzo, R.; Cederberg, H.; De Masi, F.; Elders, P. J. M.; Giordano, G. N.; Haid, M.; Hansen, T.; Hansen, T. H.; Hattersley, A. T.; Heggie, A. J.; Howald, C.; Jones, A. G.; Kokkola, T.; Laakso, M.; Mahajan, A.; Mari, A.; Mcdonald, T. J.; Mcevoy, D.; Mourby, M.; Musholt, P. B.; Nilsson, B.; Pattou, F.; Penet, D.; Raverdy, V.; Ridderstrale, M.; Romano, L.; Rutters, F.; Sharma, S.; Teare, H.; 't Hart, L.; Tsirigos, K. D.; Vangipurapu, J.; Vestergaard, H.; Brunak, S.; Franks, P. W.; Frost, G.; Grallert, H.; Jablonka, B.; Mccarthy, M. I.; Pavo, I.; Pedersen, O.; Ruetten, H.; Walker, M.; Adragni, K.; Allesoe, R. L. L.; Artati, A. A.; Arumugam, M.; Atabaki-Pasdar, N.; Baltauss, T.; Banasik, K.; Barnett, A. L.; Baum, P.; Bell, J. D.; Beulens, J. W.; Bianzano, S. B.; Bizzotto, R.; Bonnefond, A.; Cabrelli, L.; Dale, M.; Dawed, A. Y.; de Preville, N.; Dekkers, K. F.; Deshmukh, H. A.; Dings, C.; Donnelly, L.; Dutta, A.; Ehrhardt, B.; Engelbrechtsen, L.; Eriksen, R.; Fan, Y.; Ferrer, J.; Fitipaldi, H.; Forman, A.; Fritsche, A.; Froguel, P.; Gassenhuber, J.; Gough, S.; Graefe-Mody, U.; Grempler, R.; Groeneveld, L.; Groop, L.; Gudmundsdottir, V.; Gupta, R.; Hennige, A. M. H.; Hill, A. V.; Holl, R. W.; Hudson, M.; Jacobsen, U. P.; Jennison, C.; Johansen, J.; Jonsson, A.; Karaderi, T.; Kaye, J.; Kennedy, G.; Klintenberg, M.; Kuulasmaa, T.; Lehr, T.; Loftus, H.; Lundgaard, A. T. T.; Mazzoni, G.; Mcrobert, N.; Mcvittie, I.; Nice, R.; Nicolay, C.; Nijpels, G.; Palmer, C. N.; Pedersen, H. K.; Perry, M. H.; Pomares-Millan, H.; Prehn, C. P.; Ramisch, A.; Rasmussen, S.; Robertson, N.; Rodriquez, M.; Sackett, P.; Scherer, N.; Shah, N.; Sihinevich, I.; Slieker, R. C.; Sondertoft, N. B.; Steckel-Hamann, B.; Thomas, M. K.; Thomas, C. E. E.; Thomas, E. L. L.; Thorand, B.; Thorne, C. E.; Tillner, J.; Tura, A.; Uhlen, M.; van Leeuwen, N.; van Oort, S.; Verkindt, H.; Vogt, J.; Wad Sackett, P. W.; Wesolowska-Andersen, A.; Whitcher, B.; White, M. W.; Adamski, J.; Schwenk, J. M.; Pearson, E. R.; Dermitzakis, E. T.; Vinuela, A. | |
| Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials | 1-gen-2023 | Dawed Adem, Y; Mari, Andrea; Brown, Andrew; McDonald Timothy, J; Li, Lin; Wang, Shuaicheng; Hong Mun, Gwan; Sharma, Sapna; Robertson Neil, R; Mahajan, Anubha; Wang, Xuan; Walker, Mark; Gough, Stephen; Hart Leen, M'T; Zhou, Kaixin; Forgie, Ian; Ruetten, Hartmut; Pavo, Imre; Bhatnagar, Pallav; Jones Angus, G; Pearson Ewan, R; 't Hart, L M; Abdalla, M; Adam, J; Adamski, J; Adragni, K; Allin, K H; Arumugam, M; Atabaki Pasdar, N; Baltauss, T; Banasik, K B; Baum, P; Bell, J D; Bergstrom, M; Beulens, J W; Bianzano, S; Bizzotto, R; Bonneford, A; Brorsson, C AB; Brown, A A; Brunak, S B; Cabrelli, L; Caiazzo, R; Canouil, M; Dale, M; Davtian, D; Dawed Adem, Y; De Masi, F M; de Preville, N; Dekkers, K F; Dermitzakis, E T; Deshmukh, H A; Dings, C; Donnelly, L; Dutta, A; Ehrhardt, B; Elders, P JM; Engel Thomas, C ET; Engelbrechtsen, L; Eriksen, R G; Eriksen, R E; Fan, Y; Fernandez, J; Ferrer, J; Fitipaldi, H; Forgie, Ian; Forman, A; Franks, P W; Frau, F; Fritsche, A; Froguel, P; Frost, G; Gassenhuber, J; Giordano, G N; Giorgino, T; Gough, S; Graefemody, U; Grallert, H; Grempler, R; Groeneveld, L; Groop, L; Gudmundsdóttir, V G; Gupta, R G; Haid, M; Hansen, T; Hansen, T H; Hattersley, A T; Haussler, R S; Heggie, A J; Hennige, A M; Hill, A V; Holl, R W; Hong, M G; Hudson, M; Jablonka, B; Jennison, C; Jiao, J; Johansen, J J; Jones, A G; Jonsson, A | |
| Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study | 1-gen-2022 | Wesolowska-Andersen, A.; Brorsson, C. A.; Bizzotto, R.; Mari, A.; Tura, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J. F.; Sharma, S.; Haid, M.; Prehn, C.; Artati, A.; Hong, M. -G.; Musholt, P. B.; Kurbasic, A.; De Masi, F.; Tsirigos, K.; Pedersen, H. K.; Gudmundsdottir, V.; Thomas, C. E.; Banasik, K.; Jennison, C.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, L.; Frost, G.; Thomsen, H.; Allin, K.; Hansen, T. H.; Vestergaard, H.; Hansen, T.; Rutters, F.; Elders, P.; T'Hart, L.; Bonnefond, A.; Canouil, M.; Brage, S.; Kokkola, T.; Heggie, A.; Mcevoy, D.; Hattersley, A.; Mcdonald, T.; Teare, H.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G. N.; Froguel, P.; Pavo, I.; Ruetten, H.; Pedersen, O.; Dermitzakis, E.; Franks, P. W.; Schwenk, J. M.; Adamski, J.; Pearson, E.; Mccarthy, M. I.; Brunak, S. | |
| Lipid-induced glucose intolerance is driven by impaired glucose kinetics and insulin metabolism in healthy individuals | 1-gen-2022 | Trico, D.; Mengozzi, A.; Baldi, S.; Bizzotto, R.; Olaniru, O.; Toczyska, K.; Huang, G. C.; Seghieri, M.; Frascerra, S.; Amiel, S. A.; Persaud, S.; Jones, P.; Mari, A.; Natali, A. | |
| Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity | 1-gen-2021 | Deshmukh Harshal, A; Madsen Anne, Lundager; Vinuela, Ana; Have Christian, Theil; Grarup, Niels; Tura, Andrea; Mahajan, Anubha; Heggie Alison, J; Koivula Robert, W; De Masi, Federico; Tsirigos Konstantinos, K; Linneberg, Allan; Drivsholm, Thomas; Pedersen, Oluf; Sorensen Thorkild, I A; Astrup, Arne; Gjesing Anette, A P; Pavo, Imre; Wood Andrew, R; Ruetten, Hartmut; Jones Angus, G; Koopman Anitra, D M; Cederberg, Henna; Rutters, Femke; Ridderstrale, Martin; Laakso, Markku; McCarthy Mark, I; Frayling Tim, M; Ferrannini, Eleuterio; Franks Paul, W; Pearson Ewan, R; Mari, Andrea; Hansen, Torben; Walker, Mark | |
| Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial | 1-gen-2021 | Gitelman, Se; Bundy, Bn; Ferrannini, E; Lim, N; Blanchfield, Jl; Dimeglio, La; Felner, Ei; Gaglia, Jl; Gottlieb, Pa; Long, Sa; Mari, A; Mirmira, Rg; Raskin, P; Sanda, S; Tsalikian, E; Wentworth, Jm; Willi, Sm; Krischer, Jp; Bluestone, Ja; Barr, M; Buchanan, J; Cabbage, J; Coleman, P; De La Vega, M; Evansmolina, C; Ferrara, C; Healy, F; Higgins, L; Hildinger, M; Jenkins, M; Kayton Bryant, N; Kinderman, A; Koshy, N; Kost, B; Krishfield, S; Kucheruk, O; Lindsley, K; Mantravadi, M; Mesfin, S; Michels, A; Migre, Me; Minnock, P; Mohammednur, E; Nelson, J; Nursing, A; O'Donnell, R; Olivos, D; Parker, M; Redl, L; Reed, N; Resnick, B; Sayre, P; Serti, E; Sims, E; Smith, K; Soppe, C; Stuart, F; Szubowicz, S; Tansey, M; Terrell, J; Tersey, S; Torok, C; Watson, K; Wesch, R; Willi, S; Woerner, S | |
| New insights on the interactions between insulin clearance and the main glucose homeostasis mechanisms | 1-gen-2021 | Bizzotto, R; Trico, D; Natali, A; Gastaldelli, A; Muscelli, E; De Fronzo, Ra; Arslanian, S; Ferrannini, E; Mari, A | |
| Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans | 1-gen-2021 | Cinti F.; Mezza T.; Severi I.; Suleiman M.; Cefalo C.M.A.; Sorice G.P.; Moffa S.; Impronta F.; Quero G.; Alfieri S.; Mari A.; Pontecorvi A.; Marselli L.; Cinti S.; Marchetti P.; Giaccari A. | |
| Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study | 1-gen-2021 | Bizzotto, Roberto; Jennison, Christopher; Jones, Angus G.; Kurbasic, Azra; Tura, Andrea; Kennedy, Gwen; Bell, Jimmy D.; Thomas, E. Louise; Frost, Gary; Eriksen, Rebeca; Koivula, Robert W.; Brage, Soren; Kaye, Jane; Hattersley, Andrew T.; Heggie, Alison; McEvoy, Donna; 't Hart, Leen M.; Beulens, Joline W.; Elders, Petra; Musholt, Petra B.; Ridderstrale, Martin; Hansen, Tue H.; Allin, Kristine H.; Hansen, Torben; Vestergaard, Henrik; Lundgaard, Agnete T.; Thomsen, Henrik S.; De Masi, Federico; Tsirigos, Konstantinos D.; Brunak, Soren; Vinuela, Ana; Mahajan, Anubha; McDonald, Timothy J.; Kokkola, Tarja; Forgie, Ian M.; Giordano, Giuseppe N.; Pavo, Imre; Ruetten, Hartmut; Dermitzakis, Emmanouil; McCarthy, Mark I.; Pedersen, Oluf; Schwenk, Jochen M.; Adamski, Jerzy; Franks, Paul W.; Walker, Mark; Pearson, Ewan R.; Mari, Andrea | |
| Association of artificially sweetened and sugar-sweetened soft drinks with ?-cell function, insulin sensitivity, and type 2 diabetes: the Maastricht Study | 1-gen-2020 | den Biggelaar L.J.C.J.; Sep S.J.S.; Mari A.; Ferrannini E.; van Dongen M.C.J.M.; Wijckmans N.E.G.; Schram M.T.; van der Kallen C.J.; Schaper N.; Henry R.M.A.; van Greevenbroek M.M.; Stehouwer C.D.A.; Eussen S.J.P.M. | |
| Beta-cells in youth with impaired glucose tolerance or early type 2 diabetes secrete more insulin and are more responsive than in adults | 1-gen-2020 | Utzschneider, Km; Tripputi, Mt; Kozedub, A; Mather, Kj; Nadeau, Kj; Edelstein, Sl; Hannon, Ts; Arslanian, Sa; Creegreen, M; Buchanan, Ta; Caprio, S; Mari, A | |
| Brain substrate metabolism and ß-cell function in humans: A positron emission tomography study | 1-gen-2020 | Rebelos, E; Mari, A; Bucci, M; Honka, Mj; Hannukainen, Jc; Virtanen, Ka; Hirvonen, J; Nummenmaa, L; Heni, M; Iozzo, P; Ferrannini, E; Nuutila, P | |
| Circulating palmitoleic acid is an independent determinant of insulin sensitivity, beta cell function and glucose tolerance in non-diabetic individuals: a longitudinal analysis | 1-gen-2020 | Trico D.; Mengozzi A.; Nesti L.; Hatunic M.; Gabriel Sanchez R.; Konrad T.; Lalic K.; Lalic N.M.; Mari A.; Natali A. | |
| Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study | 1-gen-2020 | Eriksen R.; Perez I.G.; Posma J.M.; Haid M.; Sharma S.; Prehn C.; Thomas L.E.; Koivula R.W.; Bizzotto R.; Mari A.; Giordano G.N.; Pavo I.; Schwenk J.M.; De Masi F.; Tsirigos K.D.; Brunak S.; Vinuela A.; Mahajan A.; McDonald T.J.; Kokkola T.; Rutter F.; Teare H.; Hansen T.H.; Fernandez J.; Jones A.; Jennison C.; Walker M.; McCarthy M.I.; Pedersen O.; Ruetten H.; Forgie I.; Bell J.D.; Pearson E.R.; Franks P.W.; Adamski J.; Holmes E.; Frost G. | |
| Different mechanisms of GIP and GLP-1 action explain their different therapeutic efficacy in type 2 diabetes | 1-gen-2020 | Grespan, Eleonora; Giorgino, Toni; Natali, Andrea; Ferrannini, Eleuterio; Mari, Andrea | |
| Disruption of fasting and post-load glucose homeostasis are largely independent and sustained by distinct and early major beta-cell function defects: a cross-sectional and longitudinal analysis of the Relationship between Insulin Sensitivity and Cardiovascular risk (RISC) study cohort | 1-gen-2020 | Mengozzi, A; Trico, D; Nesti, L; Petrie, J; Hojlund, K; Mitrakou, A; Krebs, M; Mari, A; Natali, A |