CRESPAN, EMMANUELE
CRESPAN, EMMANUELE
Istituto di Genetica Molecolare "Luigi Luca Cavalli Sforza"
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023 Poggialini F; Vagaggini C; Brai A; Pasqualini C; Crespan E; Maga G; Perini C; Cabella N; Botta L; Musumeci F; Frosini M; Schenone S; Dreassi E
Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor
2023 Contadini, C; Cirotti, C; Carbone, A; Norouzi, M; Cianciusi, A; Crespan, E; Perini, C; Maga, G; Barilà, D; Musumeci, F; Schenone, S
Truncating Variants in RFC1 in Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome
2023 Ronco R; Perini C; Curro' R; Dominik N; Facchini S; Gennari A; Simone R; Stuart S; Nagy S; Vegezzi E; Quartesan I; ElSaddig A; Lavin T; Tucci A; Szymura A; Novis De Farias LE; Gary A; Delfeld M; Kandikatla P; Niu N; Tawde S; Shaw J; Polke J; Reilly MM; Wood NW; Crespan E; Gomez C; Chen JYH; Schmahmann JD; Gosal D; Houlden H; Das S; Cortese A.
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment
2022 Di Maria, S; Picarazzi, F; Mori, M; Cianciusi, A; Carbone, A; Crespan, E; Perini, C; Sabetta, S; Deplano, S; Poggialini, F; Molinari, A; Aronne, R; Maccioni, E; Maga, G; Angelucci, A; Schenone, S; Musumeci, F; Dreassi, E
Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors
2022 Princiotto, S; Musso, L; Manetti, F; Marcellini, V; Maga, G; Crespan, E; Perini, C; Zaffaroni, N; Beretta, Gl; Dallavalle, S
A Role for Human DNA Polymerase lambda in Alternative Lengthening of Telomeres
2021 Mentegari, E; Bertoletti, F; Kissova, M; Zucca, E; Galli, S; Tagliavini, G; Garbelli, A; Maffia, A; Bione, S; Ferrari, E; d'Adda di Fagagna, F; Francia, S; Sabbioneda, S; Chen, Ly; Lingner, J; Bergoglio, V; Hoffmann, Js; Hubscher, U; Crespan, E; Maga, G
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIII beta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses
2021 Grazia Martina M; Vicenti I; Bauer L; Crespan E; Rango E; Boccuto A; Olivieri N; Incerti M; Zwaagstra M; Allodi M; Bertoni S; Dreassi E; Zazzi M; van Kuppeveld FJM; Maga G; Radi M.
High flexibility of rnaseh2 catalytic activity with respect to non-canonical dna structures
2021 Dede, M; Napolitano, S; Melati, A; Pirota, V; Maga, G; Crespan, E
Selective binding and redox-activity on parallel g-quadruplexes by pegylated naphthalene diimide-copper complexes
2021 Pirota, V; Lunghi, E; Benassi, A; Crespan, E; Freccero, M; Doria, F
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2
2021 Vicenti, I; Martina, Mg; Boccuto, A; De Angelis, M; Giavarini, G; Dragoni, F; Marchi, S; Trombetta, Cm; Crespan, E; Maga, G; Eydoux, C; Decroly, E; Montomoli, E; Nencioni, L; Zazzi, M; Radi, M
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains
2020 Nalli, M; Armijos Rivera, Ji; Masci, D; Coluccia, A; Badia, R; Riveiramuñoz, E; Brambilla, A; Cinquina, E; Turriziani, O; Falasca, F; Catalano, M; Limatola, C; Esté, Ja; Maga, G; Silvestri, R; Crespan, E; La Regina, G
Effect of alpha-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)-ones
2019 Nawrozkij M; Forgione M; Yablokov AS; Lucidi A; Tomaselli D; Patsilinakos A; Panella C; Hailu GS; Kirillov IA; Badia R; Riveira Muñoz E; Crespan E; ArmijosRivera JI; Cirilli R; Ragno R; Este JA; Maga G; Mai A; Rotili D.
Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines
2019 Fallacara AL; Passannanti R; Mori M; Iovenitti G; Musumeci F; Greco C; Crespan E; Kissova M; Maga G; Tarantelli C; Spriano F; Gaudio E; Bertoni F; Botta M; Schenone S.
Molecular docking, design, synthesis and biological evaluation of novel 2,3-aryl-thiazolidin-4-ones as potent NNRTIs
2019 Geronikaki A; Petrou A; Kartsev V; Eleftheriou P; Boga R; Bartolo B; Crespan E; Franco G; Maga G.
Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach +
2019 Tassini, S; Langron, E; Delang, L; Mirabelli, C; Lanko, K; Crespan, E; Kissova, M; Tagliavini, G; Fontò, G; Bertoni, S; Palese, S; Giorgio, C; Ravanetti, F; Ragionieri, L; Zamperini, C; Mancini, A; Dreassi, E; Maga, G; Vergani, P; Neyts, J; Radi, M
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
2018 Molinari, A; Fallacara, Al; Di Maria, S; Zamperini, C; Poggialini, F; Musumeci, F; Schenone, S; Angelucci, A; Colapietro, A; Crespan, E; Kissova, M; Maga, G; Botta, M
Identification of Broad-Spectrum Dengue/Zika Virus Replication Inhibitors by Functionalization of Quinoline and 2,6-Diaminopurine Scaffolds
2018 Kaptein S.J.F.; Vincetti P.; Crespan E.; Rivera J.I.A.; Costantino G.; Maga G.; Neyts J.; Radi M.
p15PAF binding to PCNA modulates the DNA sliding surface
2018 De March, M; Barreravilarmau, S; Crespan, E; Mentegari, E; Merino, N; Gonzalezmagana, A; Romanomoreno, M; Maga, G; Crehuet, R; Onesti, S; Blanco, Fj; De Biasio, A
How to win the HIV-1 drug resistance hurdle race: Running faster or jumping higher?
2017 Garbelli, A; Riva, V; Crespan, E; Maga, G
Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma
2017 Musumeci, Francesca; Fallacara Anna, Lucia; Brullo, Chiara; Grossi, Giancarlo; Botta, Lorenzo; Calandro, Pierpaolo; Chiariello, Mario; Kissova, Miroslava; Crespan, Emmanuele; Maga, Giovanni; Schenone, Silvia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini F; Vagaggini C; Brai A; Pasqualini C; Crespan E; Maga G; Perini C; Cabella N; Botta L; Musumeci F; Frosini M; Schenone S; Dreassi E | |
| Identification and Biological Characterization of the Pyrazolo[3,4-<i>d</i>]pyrimidine Derivative SI388 Active as Src Inhibitor | 1-gen-2023 | Contadini, C; Cirotti, C; Carbone, A; Norouzi, M; Cianciusi, A; Crespan, E; Perini, C; Maga, G; Barilà, D; Musumeci, F; Schenone, S | |
| Truncating Variants in RFC1 in Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome | 1-gen-2023 | Ronco R; Perini C; Curro' R; Dominik N; Facchini S; Gennari A; Simone R; Stuart S; Nagy S; Vegezzi E; Quartesan I; ElSaddig A; Lavin T; Tucci A; Szymura A; Novis De Farias LE; Gary A; Delfeld M; Kandikatla P; Niu N; Tawde S; Shaw J; Polke J; Reilly MM; Wood NW; Crespan E; Gomez C; Chen JYH; Schmahmann JD; Gosal D; Houlden H; Das S; Cortese A. | |
| Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment | 1-gen-2022 | Di Maria, S; Picarazzi, F; Mori, M; Cianciusi, A; Carbone, A; Crespan, E; Perini, C; Sabetta, S; Deplano, S; Poggialini, F; Molinari, A; Aronne, R; Maccioni, E; Maga, G; Angelucci, A; Schenone, S; Musumeci, F; Dreassi, E | |
| Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors | 1-gen-2022 | Princiotto, S; Musso, L; Manetti, F; Marcellini, V; Maga, G; Crespan, E; Perini, C; Zaffaroni, N; Beretta, Gl; Dallavalle, S | |
| A Role for Human DNA Polymerase lambda in Alternative Lengthening of Telomeres | 1-gen-2021 | Mentegari, E; Bertoletti, F; Kissova, M; Zucca, E; Galli, S; Tagliavini, G; Garbelli, A; Maffia, A; Bione, S; Ferrari, E; d'Adda di Fagagna, F; Francia, S; Sabbioneda, S; Chen, Ly; Lingner, J; Bergoglio, V; Hoffmann, Js; Hubscher, U; Crespan, E; Maga, G | |
| Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIII beta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses | 1-gen-2021 | Grazia Martina M; Vicenti I; Bauer L; Crespan E; Rango E; Boccuto A; Olivieri N; Incerti M; Zwaagstra M; Allodi M; Bertoni S; Dreassi E; Zazzi M; van Kuppeveld FJM; Maga G; Radi M. | |
| High flexibility of rnaseh2 catalytic activity with respect to non-canonical dna structures | 1-gen-2021 | Dede, M; Napolitano, S; Melati, A; Pirota, V; Maga, G; Crespan, E | |
| Selective binding and redox-activity on parallel g-quadruplexes by pegylated naphthalene diimide-copper complexes | 1-gen-2021 | Pirota, V; Lunghi, E; Benassi, A; Crespan, E; Freccero, M; Doria, F | |
| System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2 | 1-gen-2021 | Vicenti, I; Martina, Mg; Boccuto, A; De Angelis, M; Giavarini, G; Dragoni, F; Marchi, S; Trombetta, Cm; Crespan, E; Maga, G; Eydoux, C; Decroly, E; Montomoli, E; Nencioni, L; Zazzi, M; Radi, M | |
| New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains | 1-gen-2020 | Nalli, M; Armijos Rivera, Ji; Masci, D; Coluccia, A; Badia, R; Riveiramuñoz, E; Brambilla, A; Cinquina, E; Turriziani, O; Falasca, F; Catalano, M; Limatola, C; Esté, Ja; Maga, G; Silvestri, R; Crespan, E; La Regina, G | |
| Effect of alpha-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)-ones | 1-gen-2019 | Nawrozkij M; Forgione M; Yablokov AS; Lucidi A; Tomaselli D; Patsilinakos A; Panella C; Hailu GS; Kirillov IA; Badia R; Riveira Muñoz E; Crespan E; ArmijosRivera JI; Cirilli R; Ragno R; Este JA; Maga G; Mai A; Rotili D. | |
| Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines | 1-gen-2019 | Fallacara AL; Passannanti R; Mori M; Iovenitti G; Musumeci F; Greco C; Crespan E; Kissova M; Maga G; Tarantelli C; Spriano F; Gaudio E; Bertoni F; Botta M; Schenone S. | |
| Molecular docking, design, synthesis and biological evaluation of novel 2,3-aryl-thiazolidin-4-ones as potent NNRTIs | 1-gen-2019 | Geronikaki A; Petrou A; Kartsev V; Eleftheriou P; Boga R; Bartolo B; Crespan E; Franco G; Maga G. | |
| Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach + | 1-gen-2019 | Tassini, S; Langron, E; Delang, L; Mirabelli, C; Lanko, K; Crespan, E; Kissova, M; Tagliavini, G; Fontò, G; Bertoni, S; Palese, S; Giorgio, C; Ravanetti, F; Ragionieri, L; Zamperini, C; Mancini, A; Dreassi, E; Maga, G; Vergani, P; Neyts, J; Radi, M | |
| Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment | 1-gen-2018 | Molinari, A; Fallacara, Al; Di Maria, S; Zamperini, C; Poggialini, F; Musumeci, F; Schenone, S; Angelucci, A; Colapietro, A; Crespan, E; Kissova, M; Maga, G; Botta, M | |
| Identification of Broad-Spectrum Dengue/Zika Virus Replication Inhibitors by Functionalization of Quinoline and 2,6-Diaminopurine Scaffolds | 1-gen-2018 | Kaptein S.J.F.; Vincetti P.; Crespan E.; Rivera J.I.A.; Costantino G.; Maga G.; Neyts J.; Radi M. | |
| p15PAF binding to PCNA modulates the DNA sliding surface | 1-gen-2018 | De March, M; Barreravilarmau, S; Crespan, E; Mentegari, E; Merino, N; Gonzalezmagana, A; Romanomoreno, M; Maga, G; Crehuet, R; Onesti, S; Blanco, Fj; De Biasio, A | |
| How to win the HIV-1 drug resistance hurdle race: Running faster or jumping higher? | 1-gen-2017 | Garbelli, A; Riva, V; Crespan, E; Maga, G | |
| Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma | 1-gen-2017 | Musumeci, Francesca; Fallacara Anna, Lucia; Brullo, Chiara; Grossi, Giancarlo; Botta, Lorenzo; Calandro, Pierpaolo; Chiariello, Mario; Kissova, Miroslava; Crespan, Emmanuele; Maga, Giovanni; Schenone, Silvia |