ALTERIO, VINCENZO
ALTERIO, VINCENZO
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
2023 Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo
Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
2022 Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella
α-CAs from Photosynthetic Organisms
2022 Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
2021 DE SIMONE, Giuseppina; Alterio, Vincenzo
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
2021 Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
2020 Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy
2020 Nocentini, Alessio; Alterio, Vincenzo; Bua, Silvia; Micheli, Laura; Esposito, Davide; Buonanno, Martina; Bartolucci, Gianluca; Osman, Sameh M.; ALOthman, Zeid A.; Cirilli, Roberto; Pierini, Marco; Monti, Simona Maria; Mannelli, Lorenzo Di Cesare; Gratteri, Paola; Ghelardini, Carla; De Simone, Giuseppina; Supuran, Claudiu T.
ALPHA-CARBONIC ANHYDRASES
2019 DI FIORE, Anna; D'Ambrosio, Katia; Ayoub, Joelle; Alterio, Vincenzo; DE SIMONE, Giuseppina
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex
2019 Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity
2019 Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna
Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor
2018 Alterio V.; Esposito D.; Monti S.M.; Supuran C.T.; De Simone G.
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one
2018 Supuran, Claudiu T.; Alterio, Vincenzo; Di Fiore, Anna; D' Ambrosio, Katia; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina
Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding
2018 De Simone, Giuseppina; Angeli, Andrea; Bozdag, Murat; Supuran, Claudiu T.; Winum, JeanYves; Monti, Simona Maria; Alterio, Vincenzo
Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements.
2017 Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G
Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations
2017 DE SIMONE, Giuseppina; Langella, Emma; Esposito, Davide; Supuran Claudiu, T; Monti, SIMONA MARIA; Winum Jean, Yves; Alterio, Vincenzo
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides
2017 Bruno, Elvira; Buemi Maria, Rosa; DI FIORE, Anna; De Luca, Laura; Ferro, Stefania; Angeli, Andrea; Cirilli, Roberto; Sadutto, Daniele; Alterio, Vincenzo; Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina; Gitto, Rosaria
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition
2016 Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors
2016 Vullo, Daniela; Supuran Claudiu, T; Scozzafava, Andrea; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; Carta, Fabrizio
The anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies
2016 Di Fiore, Anna; De Simone, Giuseppina; Alterio, Vincenzo; Riccio, Vincenzo; Winum, JeanYves; Carta, Fabrizio; Supuran, Claudiu T.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors | 1-gen-2023 | Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo | |
| Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion | 1-gen-2022 | Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella | |
| α-CAs from Photosynthetic Organisms | 1-gen-2022 | Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia | |
| Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule | 1-gen-2021 | DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? | 1-gen-2021 | Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site | 1-gen-2020 | Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo | |
| A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity | 1-gen-2020 | Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella | |
| Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy | 1-gen-2020 | Nocentini, Alessio; Alterio, Vincenzo; Bua, Silvia; Micheli, Laura; Esposito, Davide; Buonanno, Martina; Bartolucci, Gianluca; Osman, Sameh M.; ALOthman, Zeid A.; Cirilli, Roberto; Pierini, Marco; Monti, Simona Maria; Mannelli, Lorenzo Di Cesare; Gratteri, Paola; Ghelardini, Carla; De Simone, Giuseppina; Supuran, Claudiu T. | |
| ALPHA-CARBONIC ANHYDRASES | 1-gen-2019 | DI FIORE, Anna; D'Ambrosio, Katia; Ayoub, Joelle; Alterio, Vincenzo; DE SIMONE, Giuseppina | |
| Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex | 1-gen-2019 | Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina | |
| Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity | 1-gen-2019 | Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna | |
| Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor | 1-gen-2018 | Alterio V.; Esposito D.; Monti S.M.; Supuran C.T.; De Simone G. | |
| Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one | 1-gen-2018 | Supuran, Claudiu T.; Alterio, Vincenzo; Di Fiore, Anna; D' Ambrosio, Katia; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina | |
| Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding | 1-gen-2018 | De Simone, Giuseppina; Angeli, Andrea; Bozdag, Murat; Supuran, Claudiu T.; Winum, JeanYves; Monti, Simona Maria; Alterio, Vincenzo | |
| Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements. | 1-gen-2017 | Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G | |
| Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations | 1-gen-2017 | DE SIMONE, Giuseppina; Langella, Emma; Esposito, Davide; Supuran Claudiu, T; Monti, SIMONA MARIA; Winum Jean, Yves; Alterio, Vincenzo | |
| Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides | 1-gen-2017 | Bruno, Elvira; Buemi Maria, Rosa; DI FIORE, Anna; De Luca, Laura; Ferro, Stefania; Angeli, Andrea; Cirilli, Roberto; Sadutto, Daniele; Alterio, Vincenzo; Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina; Gitto, Rosaria | |
| Benzoxaborole as a new chemotype for carbonic anhydrase inhibition | 1-gen-2016 | Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves | |
| Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors | 1-gen-2016 | Vullo, Daniela; Supuran Claudiu, T; Scozzafava, Andrea; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; Carta, Fabrizio | |
| The anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies | 1-gen-2016 | Di Fiore, Anna; De Simone, Giuseppina; Alterio, Vincenzo; Riccio, Vincenzo; Winum, JeanYves; Carta, Fabrizio; Supuran, Claudiu T. |